Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Susan Kironde Kizito
ID:
THE ROLE, KNOWLEDGE, ATTITUDE AND PRACTICES OF TRADITIONAL HEALERS IN THE MANAGEMENT OF SNAKE BITES: A CASE OF GULU AND KAMULI DISTRICTS, UGANDA
REFNo: HS1434ES

1.Describe the role of traditional healers in the management of snakebites. 2.Assess the knowledge traditional healers have on snakes, snake bite symptoms and signs, and management of snakebite envenoming. 3.Describe the attitude traditional healers have about snakes, and the modes of first aid they use for management of snakebites. 4.Document traditional healers’ practices when providing first aid to snakebite victims. 5.Establish the willingness of traditional healers to contribute towards establishing a community surveillance system for snakebites in Uganda.
Uganda 2021-08-04 2024-08-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 An open label, Phase 2 study to evaluate the safety and immunogenicity of an Ad26.ZEBOV booster dose in Human Immunodeficiency Virus Positive (HIV+) adults previously vaccinated with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen
REFNo: HS1350ES

• To assess the safety and tolerability of a Ad26.ZEBOV booster dose in HIV positive adults previously vaccinated with the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen.

• To assess humoral responses induced by the booster dose against EBOV glycoprotein (GP), as measured by Filovirus Animal Non-Clinical Group (FANG) Enzyme-Linked Immunosorbent Assay (ELISA) at 7 and 21 days.

 Uganda 2021-08-04 2024-08-04 Medical and Health Sciences Clinical Trial Non-degree Award
Sarah Zalwango Karen
ID: UNCST-2021-R005660
 Identifying adolescents at high risk of neurocognitive disorder: Development and validation of composite risk index.
REFNo: HS1532ES

a. To develop a CRI by combining intake data on nutrition, immune parameters and HIV status and their interactions and perform internal and external validation of CRI as predictor of ND at 12 months. We hypothesize that the CRI evaluated at intake will successfully predict progressive/incident ND 12 months later.

b. To further internally and externally validate CRI for “out-of-time-window” prediction from 24 to 36 months. We hypothesize that the CRI developed at intake but evaluated at 24 months will successfully predict progressive/incident ND at 36 months.

c. For HEU and HIV-infected children, to refine CRI into CRI-HEU and CRI-HIV, respectively, by including type of maternal ART, viral genome parameters, current cART regimen/adherence (as applicable), and their interactions. We hypothesize that the CRI-HEU and CRI-HIV developed at intake and evaluated at intake and 24 months will successfully predict ND and ND/HAND respectively, 12 months later.

 Uganda 2021-08-04 2024-08-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Goretti Nakabugo Goretti
ID: UNCST-2021-R013051
 DEVELOPING SUSTAINABLE MODELS FOR COMMUNITY-BASED PRESCHOOLS IN UGANDA
REFNo: SS714ES

The purpose of this study is to identify and refine models of ECCE provision which can help to increase its availability and enhance its quality in the context of Uganda. It is intended that these models should involve community ownership and management as far as possible and should be suitable for public subsidy in the future.

The main research questions are as follows and will apply to a variety of cases selected for in-depth and comparative study:

1. What structures, practices and resources can enable the preschool to be controlled by, and accountable to, representatives of a local community or other relevant community?

2. What structures, resources and system of funding can help to make the preschool accessible and affordable to all or most households in the locality? How far can these elements be sourced within the community?

3. What are the essential human and physical resources for the preschool to be of acceptable quality and how should the standards for these be stated for purposes of management and evaluation? How far can the community provide these resources?

4. Given the existing provision of resources, what should be the priorities for improving leadership, teaching and care in the preschool?

5. How can the preschool best be linked with schools, health and social welfare services and existing demand-side interventions?

 Uganda 2021-08-03 2024-08-03 Social Science and Humanities Non-degree Award
ANN NANTEZA SENGENDO
ID:
Assessment of integrated control of East Coast fever (ECF) by induction of acquired immunity in Ankole cattle after natural infection by early diagnosis and early treatment
REFNo: A134ES

Mainobjective
To investigate the performance of early diagnosis and early treatment of ECF as a method of reducing calf mortality and enhancing conditions for the development of endemic stability
Specific objectives
i. To determine the prevalence of ECF based on microscopic, ELISA and PCR methods.
ii. To determine the efficiency of early symptom diagnosis and early chemotherapy approach in treating natural ECF cases and induction of protective immunity against ECF in Ankole cattle in an endemic area.
iii. To design a diagnostic regimen/protocol that farmers can use to minimize cattle losses due to ECF by integrating early case symptom detection and early treatment in the routine control strategy in an endemic area.


 Uganda 2021-08-03 2024-08-03 Agricultural Sciences Non-Clinical Trial Non-degree Award
Kenneth Rubango
ID:
Feasibility Study of Nanomedicine in Uganda
REFNo: HS1485ES

Design a nanomedicine promotion package that will be shared with Makerere University, the Ministry of Health and the other healthcare providers. ,Study and evaluate the effectiveness of nanomedicine towards the existing medical education in the selected medical schools. Under this aim, the teaching staff e.g Assistant lecturers, Lecturers, Associate Professors or Professors will be interviewed for the necessary information.,Engage employers and employees in designing the feasibility study towards nanomedicine at their workplaces. Under this aim, the employers e.g Administrators, Principals or Human resource managers will be interviewed for the necessary information.,Assess employer’s willingness to support interventions geared at promoting nanomedicine at their workplaces. Under this aim, the employers e.g Administrators, Principals or Human resource managers will be interviewed for the necessary information.,Conduct formative research to assess existing and needed support for nanomedicine in the selected medical schools. Under this aim, the Key Informant person from each medical school will be interviewed. ,To design and evaluate the feasibility study of nanomedicine in the selected Ugandan medical schools.,
 Uganda 2021-08-03 2024-08-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Cally Tann
ID: UNCST-2023-R008021
 Transitioning a Bundle for Early Detection and Intervention for Children with Developmental Disability to Scale for Low-Resource Settings
REFNo: SS910ES

WS1: To develop harmonised training materials to promote and support high fidelity implementation of the PDC and ABAaNA EIP at scale.
WS2: To further develop the Ubuntu multi-media web platform including development of a pilot mobile tablet application to promote programme accessibility and fidelity.
WS3: To identify existing approaches to livelihood support for caregivers of children with developmental disability in low- and middle-income countries to inform the development of a livelihoods component to the EIP.
WS4: To develop a scale-up strategy, business model and marketing strategy to disseminate the PDC and EIP approaches to a wider audience.
WS5: To define a sustainable monitoring, evaluation and learning strategy to track implementation of the PDC and EIP at scale

 UK 2021-08-03 2024-08-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick Kijjambu Nsambu
ID:
PERFORMANCE OF MICROFINANCE DEPOSIT TAKING INSTITUTIONS; A MACROECONOMIC AND INSTITUTIONAL PERSPECTIVE IN UGANDA
REFNo: SS932ES

5To establish the relationship between ownership structure and performance of MDI in Uganda. ,i4 To establish the competition on the performance of MDIs in Uganda.,3To establish the impact of outreach on performance of MDIs in Uganda.,To establish the impact of external factors on the performance of MDIs in Uganda.,To establish the impact of internal factors on the performance of MDIs in Uganda.,To establish performance of microfinance deposit taking institutions in Uganda,
 Uganda 2021-08-03 2024-08-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
 Validation of the new BP- TB LAM LFA test in well-defined urine and plasma samples collected from TB patients irrespective of HIV status
REFNo: HS1527ES

Primary:
• To collect urine and plasma samples for validation studies on the selection of the best prototype among the six TB LAM LFA prototypes generated by Biopromic (BP)

Secondary:
• To create a biobank of plasma and urine for future validation of novel TB diagnostics

 Uganda 2021-08-03 2024-08-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
TUKAMUHABWA EVARISTO
ID:
Curriculum innovation, school environment and physics teacher effectiveness. The case of the SESEMAT program in Kabale Municipality, Uganda
REFNo: SS837ES

1. To establish the relationship between curriculum innovation and teacher effectiveness.
2. To find out the relationship between school environment and teacher effectiveness.
3. To establish whether school environment has a moderating effect on the relationship between curriculum innovation and teacher effectiveness.

Uganda 2021-08-02 2024-08-02 Social Science and Humanities Non-Clinical Trial Degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 Uganda Overseas Labor Recruitment—Forced Labor Prevalence Study
REFNo: SS940ES

Specific objectives
In specific terms, the study will generate data that establishes the:

a) Prevalence of forced labour and labour exploitation among overseas (middle east) labour returnees to Uganda

b) Characteristics of overseas labor, including hours worked, renumeration, freedom of movement, and recruitment among others

c) Determining the profiles of the different segments in the subpopulations among labour migrants
 Uganda 2021-08-02 2024-08-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniella CHUSYD Elyse
ID:
Anthropogenic related stress on reproduction in African forest elephants (Loxodonta africana cyclostis)
REFNo: NS137ES

(i) To determine how human activity influences elephant stress and reproduction.

(ii) To assess Elephants’ allostatic load (measure of the wear and tear on the body) in relation to proximity to humans.

(iii) To determine Elephants’ reproductive cycling status (is the elephant cycling or not) in relation to the elephant’s allostatic load.

USA 2021-07-30 2024-07-30 Natural Sciences Non-degree Award
Joeri Smits Smits
ID: UNCST-2021-R013841
 Reducing comparison frictions in the Ugandan credit market
REFNo: SS733ES

• To evaluate the source of comparison frictions for borrowers in the Ugandan credit market: cognitive cost of calculating the total cost of credit versus a lack of information on cost (components).
• To elicit valuations (Willingness-To-Pay (WTP))
• To evaluate the effectiveness of three types of interventions in terms of the extent to which they can help (potential) borrowers’ access cheaper and/or larger loans:
- Price aggregator tool, requiring the user to collect the pricing data him/herself
- Information provision, in the form of a table showing the potential borrower the interest rate, its calculation method, and the various fees and charges associated with a comparable loan from different institutions.
- A price aggregator that at once provides the Total Cost of Credit for a comparable loan across institutions.
 Netherlands 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Obot Obot
ID:
Uptake of Public Health Practices for Prevention of COVID-19 among Refugees, Pastoralist Communities, Truck Drivers and Slum Dwellers in Uganda
REFNo: SS838ES

1) Establish how culture, information, attitudes and practices unique to targeted communities influence the risk of COVID-19 transmission.
2) Promote culturally sensitive radio and mobile phone communication to enhance awareness of the COVID-19 prevention; specifically, the relevance and the importance of community engagement and local solutions.


3) Examine the role of trust in health organization with the aim to build local community capacity to respond to pandemics, and to gather local evidence that can inform health policy and humanitarian response.

 Uganda 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Semulimi Weil Matabi
ID: UNCST-2021-R013568
 SERUM BIOMARKERS OF VASCULAR ENDOTHELIAL CELL ACTIVATION AMONG PEOPLE LIVING WITH HIV ON LONG-TERM ANTI-RETROVIRAL THERAPY IN UGANDA.
REFNo: HS1468ES

• To describe the serum levels of biomarkers associated with vascular endothelial cell activation among PLWHA on long term ART.
• To determine the factors associated with vascular endothelial cell activation among PLWHA on long term ART.

 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adrian Muwonge
ID:
Tracking Haulage in East Africa to support COVID-19 surveillance- THEA-C19
REFNo: HS1565ES

The objectives of this study is to develop and test a digital track and trace system(DTTS) tailored to haulage in Uganda which is at the centre of the East African haulage network. By consultatively doing this, we ensure it meets the recommended standards of DTTS but also examine its impact on sector, public benefit, as well as the legal, ethical and individual rights boundaries.
 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
 Expert Clients’ delivered Cognitive Behavioral Therapy for Reducing Self-Stigma among HIV positive Pregnant Young Women and Adolescent Girls Living in Slums Areas of Kampala, Uganda
REFNo: HS1488ES

This research broadly aims to provide evidence about expert client-delivered CBT model for reducing HIV Self-stigma in a resource limited setting.To achieve this, four interrelated questions are proposed;
1) How effective is the expert client-delivered CBT model in reducing or influencing self-stigma?
2) Can trained expert clients effectively provide CBT sessions?
3) Can expert client-delivered CBT model be accepted by clients and implementers?
4) What are the factors that contribute to acceptance of CBT delivered by expert clients?
5) What are the contextual factors that favor or hinder implementation of the expert client-delivered CBT model?

 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
 A collaborative research program between Michigan State University and Makerere University psychiatry departments on climate change and gender-based violence in Uganda
REFNo: HS1517ES

To conduct key-informant interviews with key personnel in the identified organizations and other stakeholders.,To identify institutions and stakeholders in based in Kampala but who work in other Ugandan regions as well related to climate change mitigation and adaptation and GBV prevention.,To establish the initial activities and steps for the development of a joint MSU-MU research program in mental health factors associated with GBV and climate change. ,
 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 Implementation Science and Impact evaluation of the parenting for respectability programmes: A hybrid CRCT Design”
REFNo: SS900ES

The overall objective of this study is to conduct a cRCT evaluation of PfR to test its effectiveness and cost-effectiveness for reducing violence against children and gender based violence.

1. Test the effectiveness of PfR in modifying key outcomes on parent-child relationships and relationships between partners that underlie violence against children and girls/women.
2. Examine the cost effectiveness of PfR using incremental cost-effectiveness analyses (CEA) based both on the primary outcomes of harsh parenting and partner conflict as well as on disability-adjusted life years (DALYs).
3. Examine how three implementation variables – rural vs peri-urban locality, previously established groups vs new groups, and professional vs non-professional facilitators – affect participation, programme fidelity, and quality of delivery (measured quantitatively);
4. Examine the impact of implementation variables – participant engagement and quality of delivery by facilitators – on primary outcomes of parent- and child-report of harsh parenting and partner conflict.
5. Qualitatively investigate the five elements of implementation: (i) what training facilitators need (length, follow-up, who delivers training, location, etc.); (ii) what supervision facilitators need (frequency, by whom, nature of feedback, etc.); (iii) targeting of PfR at the most vulnerable families and how this can be done; (iv) disseminating PfR’s messages beyond those participating in group sessions to operate at a community, as well as individual, level; (v) differences between Wakiso and Amuru Districts in facilitative and hindering contextual factors. We will explore how these affect participation, programme fidelity, quality of delivery, participant response and community-wide impact.

 Uganda 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Erisa Mwaka Sabakaki
ID: UNCST-2019-R001625
 DESIGN AND FABRICATION OF A LUMBAR MODIFIED SPINAL BRACE
REFNo: HS1558ES

Our main objective is to design, fabricate and test a modified fit-for-purpose lumbar orthosis through use of locally available raw materials whose design can be adopted by different orthopaedic workshops in low income countries. This will be achieved through the following sub aims;
1. Conduct a needs assessment to determine the needs and requirements of people with low back pain and derive specifications for a modified brace well suited for use by people in LICs.
2. Test and assess the functionality of the modified brace using simulations.
3. Fabricate a sturdy brace with locally sourced components that suits the specifications derived from the simulations so as to make it suitable for use in low income countries.

 Uganda 2021-07-30 2024-07-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allen Kabagenyi
ID:
Accelerating Covid-19 Vaccine Acceptance and Uptake in Uganda: Snapshot Study
REFNo: SS951ES

(3) To assess the community perceptions and barriers towards COVID-19 vaccine uptake.,The general objective of the study is to explore the factors and facilitators for COVID-19 vaccination acceptance and uptake. ,To explore the demographic and socio-economic factors associated with accelerated uptake and acceptance to receive a COVID-19 vaccination. ,(1) Examine the preparedness of the population and essential workers to receive the COVID-19 vaccine. ,
 Uganda 2021-07-30 2024-07-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Abubakar Mustafa Sadik
ID: UNCST-2021-R013642
 Willingness to use genetically modified crops: Case study of communities in Uganda
REFNo: SS738ES

General objective: To evaluate the willingness of communities in Uganda to use genetically modified (GM) crops in order to inform policies and develop targeted interventions and programs towards the introduction and scaling up of GM crops in the Ugandan market. Specific objectives: a) To assess level of knowledge of communities of GM crops in Bushenyi, Jinja and Wakiso districts b) To evaluate perceptions of communities towards GM crops in Bushenyi, Jinja and Wakiso districts c) To assess the factors that contribute towards the knowledge and perceptions of communities towards GM crops in Bushenyi, Jinja and Wakiso districts d)To link willingness to use GM crops with the knowledge and perceptions of communities in Bushenyi, Jinja and Wakiso districts
 Uganda 2021-07-29 2024-07-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hanifah Nabbanja
ID:
Characterizing oncology-related emergencies among cancer patients attending the emergency unit of Uganda Cancer Institute, Kampala, Uganda in 2019
REFNo: HS1282ES

(1) To describe the demographics and tumor characteristics, laboratory markers, and the presenting signs and symptoms in cancer patients attending the emergency unit of the Uganda Cancer Institute (UCI), Uganda from 01 January 2019 to 31 December 2019.

(2) To determine the factors associated with the different clinical presentations of oncology-related emergencies among cancer patients attending the emergency unit of the Uganda Cancer Institute (UCI), Uganda from 01 January 2019 to 31 December 2019.
 Uganda 2021-07-29 2024-07-29 Medical and Health Sciences Non-degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Nutritional Quality and Safety of Complementary Foods for Children in Landslide-prone Bududa District
REFNo: HS982ES

(i) Describe the diversity of meals and food combinations commonly used in the complementary feeding of children 6-23 months old in Bududa district. (ii) Analyse the nutrient and chemical composition of commonly used raw and cooked complementary foods. (iii) Identify the type and levels of micro-organisms in the food and water commonly used for complementary feeding.
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
 COVID-19: Assessment of the COVID-19 Response in Eastern, Central and Western Africa
REFNo: HS1121ES

The aim of this research is to assess and curate the (i) response to the COVID-19 pandemic in Africa and the outcomes in terms of COVID-19 control and (ii) continuity of essential non-COVID-19 services within the COVID-19 period, to inform the COVID-19 response and recovery as well as health system resilience to future disease outbreaks in Africa.
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-degree Award
Diane Nabikolo
ID:
DEVELOPMENT OF A SAFE READY TO EAT BHAJIA SNACK FORTIFIED WITH GRASSHOPPER (Ruspolia differens) FLOUR IN UGANDA
REFNo: A121ES

i. To establish food safety knowledge, attitudes and indigenous practices associated with safe harvesting and processing of R. differens at the household level.
ii. To determine potential allergens associated with R. differens and prevalence of allergic reactions from their consumption and handling
iii. To evaluate the effect of processing on quality and safety of bhajia snack enriched with R. differens flour
iv. To determine consumer preferences and willingness to pay for value-added ready to eat bhajia snack fortified with R. differens flour.

 Uganda 2021-07-28 2024-07-28 Agricultural Sciences Non-Clinical Trial Degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 Pregnancy Associated Tuberculosis: Immunological and Clinical Outcomes of Exposed Infants.
REFNo: HS1396ES

4. To determine TB treatment outcomes of mothers with pregnancy associated tuberculosis.,3. To determine the prevalence of maternal comorbidities such as hyperglycaemia, malaria, HIV, syphilis and anaemia.,2. To explore the concept of congenital TB (defined as TB acquired during the intrauterine period or during the normal birth process) among infants born to women with active TB.,Secondary objectives 1. To estimate the prevalence of active TB among pregnant and postpartum mothers seeking care from antenatal clinics and TB treatment units.,3. To describe the clinical outcomes of the women with pregnancy associated TB (defined as a diagnosis of TB during pregnancy or within six months of the postpartum period) and their exposed infants at the different time points. ,2. To explore, in a subset of infants, T cell, B cell and NK cell responses following stimulation with TB antigens.,Primary objectives 1. To compare antibody vaccine responses to BCG, measles, tetanus among children born of mothers diagnosed with TB infection or disease during pregnancy or mothers on TB treatment within a six months’ postpartum period.,To compare antibody vaccine responses in children born of mothers diagnosed with diagnosed with TB infection or disease during pregnancy or mothers on TB treatment within a six months’ postpartum period.,
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Evaluating the acceptability of the Aqua Research STREAM Disinfection Generator in healthcare facilities in Uganda
REFNo: HS1467ES

The proposed acceptability study will evaluate levels of user and key stakeholder acceptability of the STREAM at the end of the initial introduction stage. Results will inform national STREAM introduction strategies
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
 Prevalence of Soil transmitted HElminths and correlation with Cardiovascular risk factors among patients with drug resistant TuBerculosis in Uganda: a cross sectional multi-center study (SHEC-TB study)
REFNo: HS1521ES

2. To establish the correlation between soil transmitted helminths co-infection and BMI, HbA1C, blood pressure, serum lipids and the CVR score among patients with DR-TB in Uganda,1. To determine the burden of soil transmitted helminths co-infection among patients with DR-TB in Uganda,
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
 Rapid Research in Diagnostics Development for TB Network (R2D2 TB Network) Study
REFNo: HS1482ES

1. To evaluate early and late prototypes of novel TB diagnostics to provide feedback to developers on performance and usability, inform further development and identify potential strategies for use in endemic settings.
2. To conduct large-scale, multi-center assessments of the accuracy and usability of design-locked novel TB diagnostics, including in special populations, to facilitate World Health Organization (WHO) policy review.
3. To assess the potential costs and epidemiological impact of novel TB diagnostics alone or in combination with current tests and algorithms to inform their further assessment and/or the WHO policy review process.
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhona Baingana Kezabu
ID: UNCST-2021-R013638
 THE 2021 DHS-8 PILOT
REFNo: HS1529ES

To compare hemoglobin concentrations between venous blood, a single drop of capillary blood, and a pooled capillary blood sample in children age 6-59 months and non-pregnant women age 15-49 in a laboratory setting and a field setting,To program and pilot collection of other types of data (for assessing/ensuring interview data quality),To improve various aspects of the CAPI data capture process,To test the computer-assisted personal interviewing (CAPI) data collection application for new sections of the questionnaire ,To understand the performance of selected new core questions and modules with respect to aspects that can be assessed through cognitive interviewing: comprehension, retrieval, judgement, and response,To test selected core questions, new modules, the Domestic Violence module, and a number of the CAPI innovations under field conditions for the eighth round of The Demographic and Health Surveys (DHS) Program. ,
 Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Namale
ID:
Post-discharge Care for Stroke patients in Uganda: barriers and enablers of appropriate secondary preventive care, coping mechanisms and access to rehabilitation service
REFNo: HS1522ES

Overall aim
To improve the quality of life of stroke survivors in Uganda by examining the barriers and enablers of appropriate care and support following discharge from hospital.

Specific objectives
1. To examine the barriers and enablers of stroke survivors’ participation in self-reported home-based physical activity and adherence to clinic follow-up schedules post-discharge

2. To document the experiences and opinions of facility-based health care providers on post-discharge follow-up and care for stroke patients

3. To describe the coping mechanisms among stroke survivors and their caregivers after discharge (a) adjustment to lifestyle behaviour post-stroke b) needs and concerns; c) depression symptoms

4. To document barriers and facilitators related with access to rehabilitation services among stroke patients post-discharge

Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Agaba
ID:
A framework for improving the effectiveness of integrated nutrition interventions in Uganda
REFNo: HS1549ES

1. Evaluate the program design, selected nutrition, and health outcomes among women and children under 5 years at baseline and at the end of the Community Connector interventions.
2. Explore the experiences of the implementers and the beneficiaries of the Community Connector interventions.
3. Evaluate the effectiveness of the Community Connector interventions on nutrition and health outcomes among women and children under 5 years.
4. Develop and validate a framework for improving effectiveness of integrated nutrition interventions for implementation in resource-poor settings.

Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Degree Award
Lore Vandewalle
ID: UNCST-2021-R014028
 Small Firm Diaries with carpenters in Uganda
REFNo: SS919ES

The main objective of this research is to understand the frictions in the market for outputs that hamper the growth of small-scale carpenters in Uganda. We will write a descriptive paper that outlines the frictions we observed. Given the large number of programs targeting MSMEs to foster employment growth in low-income countries, the recommendations that will emerge from our project will be useful to policy makers operating at local, national and supra-national levels. The second objective is designing an intervention tailored to remove the most important friction we observed in the market for outputs. We will test this intervention using a randomized control trial and will estimate its causal effect on the growth of small-scale carpenters. Growth will be measured through changes in revenues, profits, productivity and employment. This should be informative to both academics and policy makers as well. The intervention is not yet defined, as we want to use the data to identify the most prominent friction in the market for outputs that limits the growth of carpenters. We will request an amendment to this IRB as soon as it has been designed. The final objective is assembling unique data on small-scale carpenters in Uganda. As detailed in the methodology subsection below, we will create two unique panels that will allow us to map a complete, real-time characterization of the performance of small enterprises, decision-making and shock responses of entrepreneurs, inputs’ usage and business relationships, including partner-specific trade interactions. These datasets are instrumental to accomplish the first two objectives: it provides the information needed to understand the frictions in the markets for outputs (main objective) and to define the intervention (objective 2). We list the datasets as a separate objective, as these will become public and can thus be used by policy makers, other researchers and students as well.
Belgium 2021-07-27 2024-07-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ronald Twongyirwe
ID:
Analysis of past and projected future land use change and its impact on sediment fluxes in the Rwizi catchment
REFNo: NS147ES

. Firstly, the project aims at strengthening the academic research capacity at the universities of Mbarara and Gulu (Uganda) by means of the training of two PhD-researchers and several postdoctoral researchers in the field of integrated watershed management. Secondly, the project will develop fundamental research on the, hitherto largely overlooked, coupling between demographic developments on the one hand, and the degradation of soil and water resources on the other hand. Thirdly, the results from this fundamental research will be translated into landscape transformation models that will allow land managers and policymakers to evaluate alternative devel-opment pathways for the catchment.
Uganda 2021-07-26 2024-07-26 Natural Sciences Degree Award
SHANI BUDIGOLI DEODATUS
ID:
Prevalence, clinical manifestations, relationship with viral load of cutaneous disorders among children and adolescents living with HIV attending Mbarara Regional Referral Hospital.
REFNo: HS1265ES

1. To determine the prevalence of cutaneous disorders among children and adolescents living with HIV attending pediatric infectious Diseases' clinic at MRRH.
2. To describe the clinical manifestations of cutaneous disorders among children and adolescents living with HIV attending paediatric infectious Diseases’ clinic at MRRH.
3. To determine the relationship of cutaneous disorders and viral load among children and adolescents living with HIV attending pediatric infectious Diseases’ clinic at MRRH.
4. To assess the relationship between cutaneous disorders and CD4 counts among children and adolescents living with HIV attending pediatric infectious Diseases’ clinic at MRRH.



 Tanzania 2021-07-26 2024-07-26 Medical and Health Sciences Degree Award
Timothy Kiyemba
ID:
Protocol for conducting the beneficiary survey for the USAID Defeat TB project.
REFNo: HS1518ES

The purpose of this beneficiary survey is to assess the results of project implementation with regard to health workers, TB patients and the general community after 3 years of activity implementation in Kampala, Wakiso and Mukono districts.
 Uganda 2021-07-26 2024-07-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda  Boonabaana
ID:
Developing and displacing the 21st century city: mapping the spatial strategies and impacts of global retail investment
REFNo: SS916ES

1.To understand the geographic contexts of global retail capital investment; 2. To trace and understand its geographic transformations; 3. To understand and create grounded and sustainable responses.
Uganda 2021-07-26 2024-07-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Samuel Kabwigu
ID: UNCST-2020-R014735
 ENHANCING UNDERSTANDING OF ADOLESCENT PREGNANCY IN UGANDA: TOWARDS FUTURE IMPLEMENTATION
REFNo: HS859ES

1. Examine how familial relationships influence adolescent pregnancy in Luuka district.
2. Explore factors in the community, (such as ICTS, policies and regulation, or health services) that influence adolescent pregnancies in Luuka District.
3. Assess ways of enhancing familial relationships as a meditative approach that will reduce rates of adolescent pregnancies in Luuka district.

 Uganda 2021-07-23 2024-07-23 Medical and Health Sciences Non-Clinical Trial Degree Award
Rottenberg Esther Sophia
ID:
Making evidence on antimicrobial resistance: a historical and ethnographic study across the UK and Uganda
REFNo: SS622ES

To show how evidence on antimicrobial resistance is produced with the help of a model.
2) To understand how the context of Hoima shapes the production of knowledge on antimicrobial resistance.
3) To investigate the negotiations taking place within the context of a transnational, interdisciplinary research collaboration.
Germany 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Jonathan Kajjimu
ID: UNCST-2021-R013696
 MATERNITY CARE FOR WOMEN REFUGEES FROM NAKIVALE REFUGEE RESETTLEMENT: A NEEDS ASSESSMENT
REFNo: SS874ES

1. To determine the socio-demographic characteristics of pregnant refugee women and recently delivered refugee mothers from Nakivale refugee settlement. 2. To describe the experiences of pre-pregnancy, pregnancy, childbirth, postnatal periods, and maternity services available to refugee pregnant women and newly delivered refugee mothers from Nakivale. 3. To identify gaps in maternity care delivered to refugee pregnant women and newly delivered refugee mothers from Nakivale refugee settlement. 4. To acquire opinions of maternity services providers, and refugee pregnant women, and newly delivered refugee mothers from Nakivale refugee settlement on how to improve the refugee pregnancy outcomes.
Uganda 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Katherine Fiorillo Fiorillo
ID:
Measuring Women's Empowerment in Agroforestry Activities in Northern Uganda
REFNo: SS799ES

Research Questions:

● What is the baseline level of women’s empowerment in agroforestry in the project target area?
● How can project activities better address issues of women’s empowerment in agroforestry in the target area?
The main objectives of this research study, listed above, are to understand the baseline level of women’s empowerment and how the project can better respond to these issues. The baseline will be used to both inform and to monitor the project progress towards women’s empowerment. A strong evidence base will allow Kijani to adapt programming to better meet the needs of the community. Qualitative protocols will ensure that the community’s needs and values are being expressed fully in the research process.

USA 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Alex Bakenga
ID: UNCST-2021-R014039
 Outcomes of treatment with ADT and chemotherapy in patients with metastatic prostate cancer at the Uganda cancer institute
REFNo: HS1542ES

Objective 1: To describe the biochemical response (TPSA) of patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute. Objective 2: To determine the 1, 3 and 5-year survival among patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute. Objective 3: To determine predictors of 1, 3 and 5-year survival among patients with metastatic prostate cancer treated with ADT and chemotherapy at the Uganda cancer institute.
Uganda 2021-07-22 2024-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
SARAH NAWOOVA
ID:
COACHING AND LECTURERS' SUPERVISION SKILLS IN NATIONAL TEACHERS' COLLEGES IN UGANDA
REFNo: SS891ES

1. TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' REFLECTIVE QUESTIONING SKILLS.
1.TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' OBSERVATION SKILLS.
3.TO EXAMINE THE RELATIONSHIP BETWEEN COACHING AND LECTURERS' FEED BACKING SKILLS.

 Uganda 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Degree Award
Benon Asiimwe Byamugisha
ID:
COVID-19 and Antimicrobial Resistance in East Africa: impact and response (CARE)
REFNo: HS1519ES

To establish how community members have received and responded to health messages on COVID-19,To examine how the COVID-19 crisis is affecting patient treatment seeking, drug use, and understanding of illness, and how this is affecting the wider landscape of AMR,To the establish antibiotic provision landscape from the perspective of drug sellers, pharmacists, traditional medicine providers, and formal healthcare workers,To investigate how COVID-19 may be modifying patients’ treatment seeking behaviour, their usage of medicines/ABs and affecting access to and provision of ABs in the therapy landscape in Uganda,
 Uganda 2021-07-22 2024-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mauro Giacomazzi
ID:
Effectiveness of the Whole School System Approach in Fostering Critical Thinking among Learners in Ugandan Secondary Schools
REFNo: SS931ES

Main objective To investigate how the whole school system approach to critical thinking contributes to the development of leaners’ cognitive abilities in Ugandan secondary schools. Specific objectives (i) To establish the meaning of critical thinking in the Ugandan context. (ii) To explore how teachers can improve their teaching and learning through the critical thinking activation approach. (iii) To explore how critical thinking can be appropriately assessed in the Ugandan secondary school context. (iv) To establish the extent to which the whole school system approach contributes to the development of critical thinking abilities of Ugandan secondary school learners. (v) To establish individual, school and home related factors that influence critical thinking abilities of Ugandan secondary school learners. (vi) To explore the strategies that Ugandan secondary school teachers use in preparing and delivering critical thinking augmented lessons.
 Italy 2021-07-22 2024-07-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robert Opika Opoka
ID: UNCST-2021-R014036
 The role of prolonged exposure to parasitemia in the high morbidity in children with Sickle cell anaemia in Uganda
REFNo: HS1496ES

Primary Aims
1. To determine the rate of parasite clearance during artesunate therapy in children with sickle cell anaemia compared to children without SCA.
We hypothesize that children with SCA will experience parasite clearance half-life times exceeding the WHO-defined standard of 5 hours when treated with artemisinins for P. falciparum malaria, whereas children without SCA will not experience this delayed parasite clearance.

2. To determine the association between parasite clearance rate and risk of vaso-occlusive crisis, severe anaemia, and any hospitalisation in children with SCA.
We hypothesize that prolonged parasite clearance will correlate with increased risk of SCA-related sequelae.

3. To determine the association between kidney and splenic function and parasite clearance half-life during artesunate treatment for malaria.
We hypothesize that impaired renal function (estimated creatinine clearance) and splenic function (presence of Howell-Jolly bodies) will correlate with increased parasite clearance half-life.

Secondary Aims
1. To determine the incidence of treatment failure (new clinical malaria within a 28-day follow-up period after microscopy-confirmed parasite clearance) after artemisinin combination therapy for malaria
2. To detect and measure the prevalence of parasite genetic markers of artemisinin resistance in Jinja

 Uganda 2021-07-21 2024-07-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Nyonyintono Mwangwa
ID: UNCST-2023-R005636
 Feasibility of Use of the PATH bCPAP Kit including Oxygen Blenders in a Neonatal Population in Uganda
REFNo: HS650ES

Primary Objectives: 1. To assess the operational feasibility of using the PATH bCPAP kit including, when appropriate, in-line oxygen blending on neonatal patients. 2. To assess the usability and acceptability of the PATH bCPAP kit with oxygen blenders by healthcare workers. Secondary Objective: 1. To report clinical characteristics, demographics and outcomes of patients treated with the PATH bCPAP kit and blenders in a newborn care unit in rural Uganda.
 Uganda 2021-07-19 2024-07-19 Medical and Health Sciences Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
 Using a behavioural approach to design an antimicrobial stewardship intervention in healthcare facilities in Kampala, Mukono and Luwero Districts, Uganda
REFNo: HS1303ES

1. To explore the barriers to and facilitators for rational use of antibiotics and setting up AMS programs in HCFs in Uganda.
2. To develop, pilot an AMS behavioural intervention and assess its acceptability, feasibility and effect to foster appropriate antibiotic prescription in HCFs in Uganda.
3. To assess the cost of the intervention in fostering rational use of antibiotics in Uganda.

 Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Non-degree Award
Shevin  Jacob Thomas
ID:
AN OBSERVATIONAL STUDY TO ASSESS THE UTILITY OF BEDSIDE ULTRASOUND SCAN IN SEPSIS TREATMENT AMONG HOSPITALIZED ADULTS IN UGANDA
REFNo: HS1499ES

General objective: To describe the potential utility of bedside ultrasound scanning in evaluating adult patients with suspected sepsis admitted to hospitals in Uganda Specific objectives: 1. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings consistent with intravascular fluid depletion. 2. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings suggestive of intolerance to high volume intravenous fluid. 3. Estimate the proportion of patients admitted to the medical emergency unit with suspected sepsis who have ultrasound findings that identify a potential source of infection. 4. Determine the feasibility of delivering POCUS to evaluate non-pregnant adult patients with sepsis by clinicians who are not specialized in radiology.
USA 2021-07-16 2024-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Conrad Muzoora Kihembe
ID: UNCST-2019-R001432
 Determination of Adequate TUberculosis Regimen in Adults and adolescents hospitalised with HIV-associated severe immune suppression (Acronym: DATURA).
REFNo: HS1487ES

Primary objective: To estimate the impact of an intensified initial phase of tuberculosis (TB) treatment on mortality at 48 weeks among HIV-infected adults and adolescents hospitalised for TB with CD4 ≤ 100 cells/μL in comparison with the standard TB regimen. Secondary objectives: To estimate the impact of an intensified initial phase of TB treatment, in comparison with the standard TB regimen, on: ¥ Mortality at weeks 8 and 24 ¥ Adverse events, including: - All grade 3-4 events - Selected grade 2 events of interest - Drug-related adverse events - AIDS defining illnesses - Paradoxical TB-associated immune reconstitution inflammatory syndrome (IRIS) ¥ TB treatment success ¥ TB recurrence ¥ Antiretroviral treatment (ART) response in terms of virological success and immunological response ¥ Adherence to TB treatment and ART ¥ Peak plasma concentrations of rifampicin and isoniazid (and its N-acetyl-metabolite) at day 3, day 7 and week. ¥ Plasma concentrations of efavirenz and dolutegravir at week 4 (i.e. 2 weeks after the onset of ART)
Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Clinical Trial Non-degree Award
Davis Ntulume Roland
ID:
A Cross Sectional Study on Exploring the Lifestyle of Makerere University Staff With an Aim of developing a Bespoke Healthy Living Program for people in Academia
REFNo: HS1500ES

Our main goal is to identify and understand the key factors that attribute a typical working day of Makerere University and inhibitors of following a heathy living programme and use this feedback
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to design a contextually appropriate and bespoke programme for adoption in the field of academia and other sectors at large. This will be achieved in the following sub aims:
1. To establish the dietary and physical activity patterns of overweight and obese staff at Makerere University College of Health Sciences staff.
2. To support overweight and obese individuals to adopt an energy restricted diet and weekly physical exercise while establishing the behavioural and social determinants of compliance to the programme.
3. To establish the effect of change on food and activity body weight and health status and recommend a bespoke healthy living programme that puts into consideration the routine, perceptions and inhibitors to living a healthy lifestyle that works for Academic staff nationwide.
 Uganda 2021-07-16 2024-07-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jude Ssempebwa
ID:
COVID-19 and the Youth Question in Africa: Piloting a Vertically Integrated Social Accountability and Advocacy Framework in the IGAD Region (COYOQA)
REFNo: SS921ES

1. To carry out a comprehensive gender analysis of the current social mobilization of youth in informing, co-designing and supporting COVID-19 pandemic emergency preparedness and response, capacity, key gaps and support needs among IGAD Member States (Ethiopia, Kenya and Uganda).
2. To build the capacity of male and female Youth Volunteers for Behavior Change (YOV4BC) in emergency preparedness, response (disaster risk reduction and management) and building resilience to impacts of COVID-19 so that they are well informed, resourced and educated about COVID-19 and its prevention measures.
3. To partner with the youth to take action within their communities through developing and institutionalizing a standardized and harmonized COVID-19 Vertically Integrated Social Accountability and Advocacy Framework for monitoring the IGAD Regional Response Strategy(IRRS) for COVID-19 Pandemic in Kenya, Uganda and Ethiopia.
4. To investigate and track gender differentiated sectoral socio-economic impacts of COVID-19 on youth and their communities and document community perceptions and response strategies.
5. To facilitate meaningful policy engagement between male and female youth and policy makers through enhanced national, sub-national and regional knowledge sharing platforms.

 Uganda 2021-07-16 2024-07-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Roselline Achola
ID:
Decision making about Family Planning use by refugee and host populations in Adjumani district, Uganda
REFNo: SS809ES

1.To explore decision making processes for FP use by refugee and host population in Adjumani district
2.To establish factors associated with FP use by women and men in the refugee and host populations in Adjumani
3.To develop and evaluate an intervention to increase FP use by refugee and host populations

Uganda 2021-07-15 2024-07-15 Social Science and Humanities Non-Clinical Trial Degree Award
Richard Munana
ID:
Chronic Kidney Disease among Patients with Diabetes and Hypertension in Nakaseke District Rural Uganda: Assessing Patient Characteristics and the Diagnostic Performance of Saliva Urea Nitrogen Strips in Chronic Kidney Disease Diagnosis When Combined with a Chronic Kidney Disease Case Finding Questionnaire and Machine Learning.
REFNo: HS1387ES

1) To determine the diagnostic performance of Saliva Urea Nitrogen (SUN) strips when combined with a chronic kidney disease case-finding questionnaires and machine learning in the diagnosis of chronic kidney diseases among patients with diabetes and or hypertension in Nakaseke district, rural Uganda. 2)To establish a Chronic Kidney Disease patients’ cohort based in the Rural Uganda Non-Communicable Disease (RUNCD) Cohort in Nakaseke, Uganda.
 Uganda 2021-07-15 2024-07-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Betty OKOT
ID: UNCST-2021-R013938
 Echoes of Antiquity in Acholiland: The Return to Te-Kwaro (Tradition) after the Civil War in Northern Uganda: RefNo:GUREC-2021-57
REFNo: SS833ES

ii. Highlight how memories, practices and unwritten laws reinforce land rights through links and attachment to the past actively conveyed in return migrations; ,3.Examine the roles and disputed effectiveness of traditional chiefs as latter-day custodians of traditional laws in modern times.,1. Recapture and retell the past through specific stories of return to abandoned homesteads ,
 Uganda 2021-07-15 2024-07-15 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charles Kiyaga
ID:
Establishing universal screening and early interventions for SCD within the selected clinical networks for prevention of early mortality in Uganda.
REFNo: HS1362ES

Primary Objectives

a)To pilot newborn screening for SCD within the clinical networks of Jinja and Lira regional referral hospital in Uganda.

b)To register patient data and medical history of babies diagnosed with SCD within the first three months of life in a shared database.

c)To initiate antibacterial and antimalarial prophylaxis among the identified SCD infants within the first three months of life.

d)To ensure that the identified SCD infants are each immunized against pneumococcus and Haemophilus influenzae type b.

e)To monitor each patient at required intervals (every three months until age two years; every four to six months from age three to five years) and update patient record in registry after each visit.

f)To estimate the incidence of SCD among infants and children identified in Jinja and Lira regional referral hospitals and identify the specific hemoglobin genotypes.

Secondary Objectives

a)To measure the 5-year survival rate of children enrolled in the newborn screening cohorts.

b)To assess the costs of newborn screening and early interventions for each site or network

 Uganda 2021-07-14 2024-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
 Using realist evaluation principles to explore existing local innovations for improving timely attendance of first antenatal care among slum dwellers of Kampala, Uganda
REFNo: SS869ES

1) To identify the existing local innovations for increasing timely attendance of first antenatal care visit and their perceived success.
2) To describe the theories of change for the innovations perceived to be successful at increasing timely attendance of first antenatal care visit.
3) To explore the underlying mechanisms (generalizable contextual factors) that favored success of innovations perceived to be successful at increasing timely attendance of first antenatal care visit among slum dwellers.

Uganda 2021-07-14 2024-07-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Naome Wandera Namakula
ID:
Assessing the effectiveness of a course for men on Women’s Land Rights Social Norms in Kenya, Tanzania and Uganda- Endline Assessment in Uganda
REFNo: SS889ES

To document the current status of knowledge, attitudes, self-efficacy, intentions and perceptions of peer norms related to women’s land and property rights among men that participated in the SYFF course in Kenya and Uganda. The changes at end-line, if any, in knowledge, attitudes, self-efficacy, intentions and perceptions of peer norms related to women’s land and property rights among participants in the SYFF course in each country will be compared to baseline status.
 Uganda 2021-07-14 2024-07-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Janet SEELEY
ID:
Menstrual health interventions, schooling and mental health symptoms among Ugandan students (MENISCUS): a school-based cluster-randomised trial.
REFNo: HS1525ES

1. To evaluate whether the MENISCUS intervention improves educational attainment and reduces mental health symptoms (primary outcomes) among Secondary girls in Uganda.

2. To evaluate whether the MENISCUS intervention improves: i) knowledge of puberty and menstruation; attitudes towards menstruation (girls and boys); ii) menstrual practices at last menstrual period (LMP); iii) knowledge and practice of pain management during LMP; iv) self-efficacy in addressing menstrual needs experiences at LMP; v) quality of life and happiness; vi) school and class absence during menses (nested cohort); vii) school and class absence overall (nested cohort); viii) prevalence of urogenital infections (bacterial vaginosis, vaginal yeast and urinary tract infections)
3. To evaluate the costs of setting up and running the intervention package, the unit cost per female student reached, and the incremental cost-effectiveness of the intervention per unit increase in selected policy-relevant outcomes, relative to optimised usual care
4. To assess whether the intervention was implemented with fidelity, and to understand the contextual factors affecting implementation, the acceptability to participants, and the intervention mechanisms. We will achieve this through a process evaluation including quantitative indicators and qualitative data collected from in-depth interviews and focus group discussions.
5. To assess the policy environment around menstrual health in Uganda, focusing on how implementing the intervention contributes to, and aligns with, the attainment of the Government policy objectives on menstruation management in schools. We will assess the policy/regulatory frameworks to which the outcomes of the intervention contribute, identify the supportive and constraining factors to the implementation of the policy guidelines and how the findings of the intervention inform refinement of current policy.

 UK 2021-07-14 2024-07-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Damalie Nakanjako
ID: UNCST-2019-R000383
 Mobile Phone-based patient follow-up Package with Medical Intervention for HIV-infected adults to promote social distancing during and after the COVID19 pandemic lockdown crisis
REFNo: HS945ES

Objectives
1.To pilot use of a Mobile Phone-based patient follow-up Package with virtual Medical Interventions (PMI) among adults receiving antiretroviral therapy (ART) at the Mulago ISS clinic.
2.To determine the effect of a PMI on the number of physical clinical visits by patients receiving ART at the Mulago ISS clinic during the one-year study period.
3.To determine the effect of PMI on continuity of ART medication during the COVID19 pandemic crisis period.
4.To determine the acceptability of the PMI approach to follow up of patients receiving long-term ART by patients and care providers at the Mulago ISS clinic

Uganda 2021-07-13 2024-07-13 Medical and Health Sciences Non-degree Award
Christina Bergey Marie
ID: UNCST-2020-R014338
 Genetic survey of bloodborne pathogens and investigation of malaria response in sanctuary chimpanzees
REFNo: NS139ES

Our proposed study has three main objectives:

1. To determine which blood-borne pathogens sanctuary chimpanzees carry, with a particular interest in those which can be transmitted from human to chimpanzee (anthroponoses) and vice versa (zoonoses);

2. To diagnose malaria infection in sanctuary chimpanzees and determine which malaria parasite species are present, with a particular interest in human malaria that may be infecting the chimpanzees; and

3. To describe the genetic mechanisms underlying the chimpanzee immune system response to malaria, and contrast this with that of humans.
 USA 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Anthony  Fuller
ID:
Assessment of Accuracy, Precision, and Feasibility of a Handheld Near-Infrared Light Device (InfraScanner 2000â„¢) in Detecting Subdural and Epidural Hematomas in Patients Admitted to Mbarara Regional Referral Hospital
REFNo: HS1010ES

Aim 1: Determine whether the InfraScanner 2000â„¢ detects epidural and/or subdural hematomas with adequate precision relative to CT scans to be used as a diagnostic tool for epidural and/or subdural hematomas.

Aim 2: Use these findings to inform the feasibility of conducting a future trial in which the InfraScanner 2000â„¢ is used as a stand-alone diagnostic tool for intracranial hematomas, and therein, to determine candidacy for decompressive craniotomies in patients who suffer TBIs in places where CT scans are not available.
 USA 2021-07-13 2024-07-13 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Vittorio Bassi
ID:
Covid-19 and the value of relationships in informal economies
REFNo: SS633ES

The overall goal of the study is to implement two exploratory phone surveys of a representative sample of Micro, Small and Medium enterprises (MSMEs) and their employees in Uganda. The survey is designed to document challenges firms are facing in investing and hiring workers during the covid-19 pandemic. In addition, the first phone survey will also embed a nudging experiment aimed at helping workers search for jobs and regain employment in the wake of the pandemic. This is an urgent study that forms a continued commitment of the researchers under BRAC Uganda partnership with Ministry of Trade, Industry and Cooperatives under Directorate of Micro and Small Medium Enterprises (MSMEs) to provide insights and learning on how the covid-19 shock has affected firm owners and employees’ relationships during the lockdown.
 Italy 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Ismay Milford Milford
ID:
The ‘Information Sector’ in East Africa, 1950s-70s: The professionalisation of journalism, broadcasting and information officers
REFNo: SS730ES

This project is a history of the ‘information sector’ as it emerged in dialogue with global patterns over the period of decolonisation in East Africa (c. 1950s-70s). I understand information not as a given technology inevitable to the language of the developmentalist state in mid-twentieth century Africa, but as a culturally constructed and moulded idea through which we can access connections that East African people of various ‘information professions’ forged with the wider world. This is in some sense a pre-history of the global debates around information that resulted in the call for a ‘New World Information and Communication Order’ in the 1970s. It argues that East Africa played an important role in the disciplinary shift from ‘information science’ to ‘mass communication’, and in the understandings of knowledge production that informed postcolonial theory.
UK 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Pierre ABOMO
ID:
Strengthening national capacity for tsetse control in Uganda
REFNo: SS725ES

1) Conduct semi-structured interviews with key personnel at COCTU and the District level to fully understand the current level of execution of the action plan for strengthening the capacity to for implementing tsetse control in Uganda

2) Conduct participatory workshops at COCTU and the District level to collaboratively assess the progress towards the establishment of a stronger and independent tsetse control system in Uganda (based on findings from objective 1).
UK 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
Eddie Wampande Mujjwiga
ID:
An evaluation of African swine fever presentation and distribution in Uganda
REFNo: NS266ES

i. Conduct a serologic, clinical, pathological, and molecular diagnostic survey of swine at a large slaughterhouse near Entebbe and Kampala, Uganda to understand the relationship between the disease status and the diagnostic status of the animals as related to Africa swine fever.
ii. Conduct a serologic analysis slaughterhouse swine to measure the immune response against exposure to the Ornithodoros moubata tick, the ASF reservoir vector in Africa.
iii. Conduct trace back to hotspots to evaluate biosecurity and conduct training of veterinarians and producers on the clinical and pathological signs of Africa swine fever.
iv. Sequence PCR positive samples to better characterize the ASF genotype and strain and its disease presentation.
v. Discuss the findings with the Ministry of Agriculture, Animal Industries, and Fisheries.

 Uganda 2021-07-13 2024-07-13 Natural Sciences Non-degree Award
Charles Batte
ID: UNCST-2021-R013587
 ASSESSING THE SOCIO-ECONOMIC IMPACT OF COVID-19 PANDEMIC ON SMALLHOLDER FARMERS’ HOUSEHOLDS AND SCHOOL-GOING CHILDREN IN BUDUDA DISTRICT, UGANDA.
REFNo: SS789ES

To assess the impact of the COVID-19 pandemic on school-going children in Bududa district.,To assess the socio-economic impact of the COVID-19 pandemic on smallholder farmers’ households in Bududa district.,
 Uganda 2021-07-13 2024-07-13 Social Science and Humanities Non-degree Award
omia Obel Francis Patrick
ID:
MULTI-STAKEHOLDER PARTICIPATION IN NATIONAL BUDGETING IN UGANDA By Francis Patrick Omia
REFNo: SS870ES

The purpose of this study is to assess the effect of multi-stakeholder participation in national budget preparation
The specific objectives of the study are as follows;
1. To examine mechanisms for Multi-stakeholder participation in budget preparation planning.
2. To analyze Multi-stakeholder participation in budget deliberation.
3. To assess Multi-stakeholder participation in budget preparation outcomes.

Uganda 2021-07-13 2024-07-13 Social Science and Humanities Non-Clinical Trial Degree Award
Nitin Wadhwa
ID:
Investigating crop raiding and ranging of habituated mountain gorillas close to park boundaries in the Buhoma sector of Bwindi National Park, Uganda.
REFNo: NS263ES

1. In this proposed study, we will walk jungle trails taken by forest rangers in the Buhoma sector to find and map signs of gorilla presence and human related activity. 2. Based on the spatial mapping exercise and density of recorded signs in a particular area, we will identify areas of high gorilla movement and ascertain how close to park boundaries gorillas are venturing and also how high are disturbance factors like human activity along the boundaries of the park. 3. We will also walk and survey the approximately 10 kms of park boundary relevant to our study (See Figure 3 in Appendix) in the Buhoma sector to map land use and cropping pattern along the edges of park (upto 150 metres). 4. Based on the the survey excersise along the boundaries of the park, we will map the land use patters and crops planted along the boundaries to create a spatial map to understand human activities along the edge park. 5. We will use data obtained from previous objectives and extrapolating it in conjunction with already existing research, we will draw conclusions and give recommendations.
India 2021-07-13 2024-07-13 Natural Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Mapping service pathways across the cancer disease trajectory in Kampala; a retrospective cohort study of timing and access to services
REFNo: HS805ES

1. To determine the number of patients accessing cancer services at Uganda Cancer Institute, Mulago Palliative care Unit, Kawempe Home Care and Hospice Africa Uganda from 2018 across 2019
2. To Identify source of referrals and target of onward referrals across these above services
3. To determine case mix across cancer services
4. To determine median number of days between referral to cancer care services and death for the study sample
5. To Identify variation in access to and referrals to cancer services by sex, age, ethnicity, diagnosis, and geographical location of residence
6. To Depict cancer pathway for patients from diagnosis to death in Kampala, Uganda

Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-degree Award
Franklin Higenyi
ID:
Gender and Public Health Space:A case of Female Doctor's career progression in Uganda Public Medical Services
REFNo: SS732ES

The study will investigate the factors that determine FDs’ career progression in UPMS.
1.4.1. Specific Objectives
1.4.1.1. To assess gender differences in career progression of female and male doctors in UPMS.
1.4.1.2. To analyze the socio-cultural and institutional factors that influence career progression of FDs in UPMS space.
1.4.1.3. To asses lived experiences of those who have managed to have career progression.
 Uganda 2021-07-12 2024-07-12 Social Science and Humanities Degree Award
Cosmas Mwikirize
ID:
Efficacy of a Deep Learning-aided Platform for Diagnosis of Breast Cancer using Ultrasound Images in the Ugandan Population
REFNo: SIR57ES

General Objective: To develop and evaluate the efficacy of a deep learning-based computer-aided platform for screening of breast cancer in the Ugandan population. Specific Objectives: 1. To collect, and curate and label breast US data from ECUREI Radiology department. 2. To develop deep learning models for lesion detection and pixel-wise segmentation in breast US images. 3. To integrate the learned models in an offline computer-aided detection platform for breast cancer, and clinically evaluate its performance. 4. To develop and integrate learned models for breast cancer detection, in a real-time portable ultrasound imaging platform.
Uganda 2021-07-12 2024-07-12 Engineering and Technology Non-degree Award
Onesmus  Ahabwe Magezi
ID:
COMMON CAUSES OF ABNORMAL VAGINAL DISCHARGE AND ANTIBIOTIC SUSCEPTIBILITY AMONG WOMEN ATTENDING THE GYGAECOLOGICAL OUTPATIENT CLINIC OF MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1456ES

1.To determine the common bacterial isolates among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital.
2.To describe the antibiotic susceptibility patterns of bacterial isolates among women with abnormal vaginal discharge attending the gynecological clinic of Mbarara Regional Referral Hospital.
3.To identify the factors associated with antibiotic resistance to commonly used antibiotics among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital

 Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Josylin Ekochu Arimpa Bananuka
ID:
Corporate Governance Practices and Performance of Pharmaceutical Manufacturing Firms in Uganda
REFNo: SS571ES

i. To analyze the effect of corporate leadership on the performance of pharmaceutical manufacturing firms in Uganda
ii. To assess the effect of boards of directors on the performance of pharmaceutical manufacturing firms in Uganda
iii. To investigate the consequences internal control systems have on the performance of pharmaceutical manufacturing firms in Uganda

Uganda 2021-07-09 2024-07-09 Social Science and Humanities Degree Award
Francis Ocheng
ID:
Helichrysum odoratissimum: Isolation and identification of bioactive compounds and their effects on oral bacteria
REFNo: HS1441ES

2-To determine whether the isolated and purified compounds from Helichrysum odoratissimum maintain their antibacterial effects on oral bacteria,1-To isolate and identify the bioactive compounds in the plant Helichrysum odoratissimum plant extracts ,The general objective of the study is to isolate and identify the bioactive compounds in the Helichrysum odoratissimum plant extracts and also further investigate the effects of the isolated compounds on oral bacteria ,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 Implementation of a "bundle of care" to improve anticoagulation control in patients receiving warfarin in Uganda and South Africa
REFNo: HS1422ES

Primary objective is to evaluate whether implementation of warfarin bundle improves time in therapeutic range

Secondary objectives are:
-To evaluate whether implementation of the warfarin bundle improves time to achieving a therapeutic INR
-Whether implementation of the warfarin bundle affects the occurrence of adverse events(death, bleeding and thrombotic events)
-whether staff find the interventions contained in the bundle acceptable
-To explore patients' experiences and acceptability of the package of care, and
-Whether the bundle represents good value for money
 UK 2021-07-09 2024-07-09 Medical and Health Sciences Clinical Trial Non-degree Award
Maureen Ayikoru
ID:
REVISED PROPOSAL IN RESPONSE TO THE OUTCOME OF ROUND 1 OF COMMITTEE REVIEW OF THE PROJECT “INDIRECT IMPACTS OF COVID-19 ON HEALTHCARE SYSTEMS: A CASE STUDY OF UGANDA’S HEALTHCARE PROFESSIONALS”
REFNo: HS1524ES

To document what lessons can be learnt from Uganda’s response to COVID-19,To analyse the impact of information and communication technologies and the media, including digital, print and broadcast media in containing the COVID-19 pandemic in Uganda.,To analyse what if any, political economy factors influence misinformation, resource reallocation and prioritisation during the ongoing pandemic and to document the perceived effects on the entire healthcare system including those most vulnerable,To identify what threats COVID-19 has had on physical, psychosocial, and overall well being of HCPs and to assess what if any formal and informal coping mechanisms have so far been available to them,To generate empirical evidence on the indirect impacts of Uganda’s response to COVID-19, focusing on the healthcare professionals.,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 Efficacy and safety of artemether-lumefantrine, pyronaridine-artesunate, artesunate-amodiaquine and dihydroartemisinin – piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda.
REFNo: HS1363ES

The general objective of this study is to assess the therapeutic efficacy and safety of artemether-lumefantrine (AL), pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP) for the treatment of uncomplicated P. falciparum malaria in three sentinel sites in Uganda.
The primary objectives are:
• to measure the clinical and parasitological efficacy of 4 artemisinin-based combination therapies (ACT), artemether-lumefantrine (AL) Pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP).
• to differentiate recrudescence from new infection of Plasmodium falciparum by molecular techniques.
The secondary objectives are:
• to evaluate the incidence of adverse events; and
• to determine the polymorphism of molecular markers mediating resistance for Artemsinin, Pyronaridine, Piperaquine and Lumefantrine resistance.
• to determine the blood concentration of Lumefantrine after treatment with Artemether- Lumefantrine .


 Uganda 2021-07-08 2024-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aubryn Sidle Allyn
ID:
Emplacing Agency in Girls' Education Practice: An Evaluation of Impact
REFNo: SS651ES

1. To evaluate the impact of CDOs’ programs on girls' Agency outcomes.
2. To understand how and why programs influence agency in adolescent girls, and what aspects of program design impede or speed this development.
3. To understand the relationship between girls’ agency and educational outcomes.
4. To evaluate the relationship between girls’ agency and teenage pregnancy incidence and determine what effect, if any, increased agency has on teenage pregnancy.
 USA 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
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