Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joseph Kizito BADA
ID:
FOSTERING DIGITAL LEARNING ENVIRONMENT FOR ADOLESCENT REPRODUCTIVE HEALTH EDUCATION
REFNo: SS1489ES

Specific Objectives
1) To sensitize and introduce a select sample of 14 teachers from 7 schools to multimedia teaching material and digital stories for teenage reproductive and mental health education with the goal of expanding teachers’ knowledge and skills in use of digital stories and multimedia content as pedagogical tools.
2) To provide hands on training on e-content curriculum creation, multimedia content development, digital stories development and digital game design for teenage reproductive and mental health education.
3) To implement multimedia educational content, multimedia content and digital stories in the 7 schools and train a total of 400 students in reproductive health education.
4) To evaluate effectiveness and impact of cartoon-based stories and multimedia educational materials on the higher level cognitive skills developent of the students.
5) To mentor 10 junior teaching staff in action research through participation in project implementation activities and disseminate the outcomes of the project in the form of online resources, academic and professional publications, conference presentations as well as policy briefs to the government agencies.

 Uganda 2022-11-11 17:20:33 2025-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jonathan Marino
ID:
How the social and material conditions of teaching influence early grades teachers’ implementation of reading pedagogies
REFNo: SS1509ES

To understand how social and material conditions shape the way teachers think about these reading pedagogies and their own teaching practice.,To understand how early primary educators in Uganda make sense of various reading pedagogies they are asked to undertake, such as mother-tongue instruction and child centered pedagogies.,To understand what are the social and material conditions of teaching experienced by early primary educators in Uganda. and how the COVID-19 pandemic has influenced these conditions.,The goal of this study is to explore how early primary teachers in Uganda make sense of and implement new pedagogical approaches to teaching reading and how the social and material constraints of their teaching environment influence their reading instruction.,
 USA 2022-11-11 17:18:21 2025-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
GRACE  MUSINGUZI
ID:
Relationship between family support and self efficacy on resilience among school going adolescent victims of trauma in Kampala, Uganda
REFNo: SS1475ES

Purpose of the study The purpose of this study is to examine the relationship between family support, self-efficacy and resilience among adolescents facing trauma in Kampala, Uganda. Specific objectives 1.To find out the prevalence of trauma among adolescents in Kampala District. 2.To find out the relationship between family support and resilience among adolescent trauma victims. 3.To find out the relationship between family breakdown and resilience among adolescent trauma victims. 4.To find out the relationship between self-efficacy and resilience among adolescent victims of trauma. 5.To explore strategies that can be put in place to foster resilience among traumatised adolescents in broken families in Kampala District.
Uganda 2022-11-11 17:16:15 2025-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi+Adherence4Youth: Optimizing the Suubi Intervention for Adherence to HIV Treatment for Youth Living with HIV in Uganda
REFNo: SS1449ES

The proposed Suubi+Adherence4Youth study seeks to unpack the Suubi intervention to identify the most impactful and sustainable components: economic vs. psychosocial components, for adolescents living with HIV (ALHIV) across the HIV care continuum. The Suubi intervention was tested as a package of four components: 1) Financial Literacy Training (FLT); 2) Incentivized Matched Youth Savings Accounts (YSA) with income-generating activities (IGAs); 3) a manualized and visual-based intervention for ART adherence and stigma reduction; and 4) Engagement with HIV treatment-experienced role models. We propose a factorial experiment to unpack and optimize the Suubi intervention to enhance scale up in health systems using the multi-phase optimization strategy (MOST) -an engineering-inspired intervention framework. Our ultimate goal is to build Suubi version 2.0 that meaningfully improves viral suppression while performing efficiently, affordably, and at scale for a sustained impact.

Aim 1. Conduct a factorial experiment (optimization trial) to test the main effects of each of the four Suubi intervention components and combinations of components (interactions) on viral suppression (primary outcome).

Aim 2. Test mediators and explore moderators that explain and modify the relationship between each of the four Suubi intervention components and viral suppression.

Aim 3. Compare the cost and cost-effectiveness of each of the four Suubi intervention components and every combination of components.

 Uganda 2022-11-11 17:11:59 2025-11-11 Social Science and Humanities Clinical Trial Non-degree Award
Moses Adriko
ID: UNCST-2019-R001787
 Field testing of a portable low-cost diagnostic for the automated diagnosis of soil transmitted helminth infections from Kato-Katz thick faecal smears
REFNo: HS2431ES

Our plan of work is to travel to Uganda, where we will initially stay in Kampala, Uganda to prepare any equipment that needs to be purchased in-country (including reagents, consumables and treatment), and engage with stakeholders at the MOHU and Vector Control Division (VCD). We will then embark on a 14-day field study, travelling to an endemic area in the Tororo district. Samples will be taken from patients and analysed using gold standard diagnostic methods and the novel portable diagnostic. Clinical diagnoses will be made using gold standard microscopy by trained technician, and the efficacy of the investigational device will be compared to these diagnoses. Feedback of technicians will also be gathered during practical demonstrations, to inform a development and translation roadmap.
 Uganda 2022-11-11 17:02:30 2025-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OKELLO DAMOI JOSEPH
ID: UNCST-2022-R011560
 The implementation of ambulatory surgery in a rural setting in Eastern Uganda
REFNo: HS2489ES

Identify factors contributing to utilization of surgical care,Develop new strategies to improve ambulatory surgery based on the results of these studies,Access the logistics and infrastructure needed to run an ambulatory surgery centre,Access surgical outcomes performed at an ambulatory surgery centre,Assess preoperative considerations for ambulatory surgery,Assess differences in outcomes of surgeries at Kyabirwa Surgical Centre,Longitudinally collect an extensive medical history, intra-operative details, clinical outcomes of the patients undergoing ambulatory procedure at KSC,Understand the prevalence of surgical diseases in the community, as compared to the prevalence of surgical diseases treated in the Centre,Analyze the data for correlative factors. The correlative factors could be the impact of demographics, medical treatment history, and/or surgical technique,Understand the needs of the patient and the community in providing better healthcare,
 Uganda 2022-11-11 17:01:15 2025-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
RICHARD NABONGO
ID:
EXPERIMENTING WITH POTTERY DESIGNS TO PRESERVE FRUITS AND VEGETABLES IN THE RURAL COMMUNITIES OF JINJA AND IGANGA DISTRICTS IN UGANDA
REFNo: SS1084ES

The aim of this study is to explore and experiment with pottery design to preserve fruits and vegetables in the rural communities of Jinja and Iganga districts through creation of a practice based pottery product.,To establish a practice-based pottery prototype product for selected villages of Jinja and Iganga districts.,To evaluate the extent to which modern technology has influenced food production and preservation practices in the local communities of Jinja and Iganga districts.,To examine the contribution of pottery to the local communities in Jinja and Iganga districts in Uganda.,To assess the influence of pottery design in today’s contemporary world. ,
 Uganda 2022-11-11 16:59:14 2025-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Namulema Edith
ID:
Feasibility of using Continuous Positive Airway Pressure via the ‘LeVe CPAP System’ among Children with Acute Hypoxemic Respiratory Failure at Mengo Hospital Kampala Uganda: A mixed methods study
REFNo: HS2478ES

1) To assess the acceptability of the LeVe CPAP system to deliver continuous positive airway pressure among children with acute hypoxemic respiratory failure at Mengo Hospital Uganda.
2) To assess the safety of LeVe CPAP system among children with acute hypoxemic respiratory failure at Mengo Hospital Uganda.

Uganda 2022-11-09 13:49:10 2025-11-09 Medical and Health Sciences Clinical Trial Non-degree Award
Zula Namubiru
ID:
HARNESSING FISHERS' KNOWLEDGE FOR SUSTAINABLE FISHERY ON LAKE VICTORIA: A CASE OF KIGUNGU FISHING GROUND WAKISO DISTRICT
REFNo: SS1511ES

1.To assess fishers’ perceived attitude, knowledge and practice on illegal fishing on Lake Victoria
2. To engage fishers especially the youth on what they can do and how best they can be enabled to sustain the fishery resource
3. To discuss with fishers’ wives/ spouses and female fish smokers on what they can do and how best they can be enabled to sustain the fishery resource
4. To understand how different stakeholders can best support fishers for the sustainable conservation of the fishery resources
Uganda 2022-11-08 14:17:17 2025-11-08 Social Science and Humanities Non-Clinical Trial Degree Award
Francis Garuzooka John
ID:
Work and learning experiences of graduates from Technical and vocational Training Institutions in Uganda. A case Study
REFNo: SS1507ES

is to understand the work and learning experiences of graduates of TVET institutions in Uganda with a view of proposing strategies for recognizing and validating non-formal workplace learning and improving productivity,4. To Evaluate how TVET graduates balance work, training apprentices and learning at their workplaces.,3. To3. To analyse the progression of TVET graduates to higher level competences and qualifications as they work. ,2. To explain the relevance of the knowledge and skills acquired by graduates of TVET institutions to the current tasks they perform at their workplaces. ,1. To find out how TVET institutions prepare their learners for work and continuous learning,
 Uganda 2022-11-08 14:14:34 2025-11-08 Social Science and Humanities Non-Clinical Trial Degree Award
Enock Matovu
ID:
COntrolling and progressively Minimizing the Burden of Animal Trypanosomiasis in Uganda [COMBAT-U]
REFNo: A237ES

i. To determine the burden, socioeconomic importance, factors driving transmission network pathways of AAT and the knowledge gaps that exist in AAT vector identification
ii. To determine the differencesin the immune responses, metabolic and genetic profiles in trypanotolerant and susceptible cattle breeds
iii. To identify molecular determinants of trypanocidal drug resistance in Trypanosoma congolense field isolates in order to develop novel molecular test(s) to detect such drug resistant strains.

 Uganda 2022-11-08 14:11:16 2025-11-08 Agricultural Sciences Non-Clinical Trial Non-degree Award
Harriet Opondo
ID: UNCST-2022-R010927
 Mental Health needs Assessment of Children ages 0-5 years Living with HIV in an Urban setting in Uganda.
REFNo: SS1484ES

1. To describe and assess the spectrum of mental health needs (magnitude and prevalence) among children living with HIV ages 0-5 years. 2. To establish the awareness of health care workers regarding mental health needs among CLHIV (0-5) years and establish existing resources and capacities to respond to these needs. 3. To explore parent training needs of parents/primary caregivers of CLHIV (0-5) years who are presenting with mental health needs.
Uganda 2022-11-08 14:09:12 2025-11-08 Social Science and Humanities Non-Clinical Trial Degree Award
lydia Bunalema
ID: UNCST-2020-R014729
 Identification and validation of anti-plasmodial activity and artemisinin pharmacokinetic enhancement potential of medicinal plants used by Ugandan communities to treat malaria symptoms
REFNo: NS431ES

To formulate a herbal product for treatment of malaria To establish the protective effect of above herbal extracts against metabolic clearance of Dihydroartemisinin in a rabbit model To determine the susceptibility (RSA0-3h and IC50) of Plasmodium falciparum to the five most common herbal extracts used in treatment of malaria symptoms across Uganda To establish through a systematic review and ethnobotanical survey medicinal plants used in treatment of malaria symptoms in communities To investigate the anti-plasmodial activity and artemisinin pharmacokinetic enhancement potential of medicinal plants used by communities across Uganda in treatment of malaria symptoms,
 Uganda 2022-11-08 14:05:34 2025-11-08 Natural Sciences Non-Clinical Trial Non-degree Award
Wilson Mugizi
ID: UNCST-2022-R009877
 Resource Based View Approach in Implementation of E-Learning in Selected Ugandan Public Universities
REFNo: SS1454ES

i. To examine the relationship between universities tangible resources and e-learning implementation during and beyond Covid-19 pandemic era in Uganda
ii. To evaluate the relationship between the universities intangible resources and e-learning implementation during and beyond Covid-19 pandemic era in Uganda.
iii. To assess the relationship between universities capabilities and e-learning implementation during and beyond Covid-19 pandemic era in Uganda.
iv. To suggest the strategies for management of e-waste resulting from implementation e-learning implementation.

Uganda 2022-11-08 14:03:00 2025-11-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kananura  Muhumuza Rornald
ID: UNCST-2019-R000239
 Improving Quality and Use of Newborn Indicators (IMPULSE): A two-phase project to describe and improve the quality and use of facility-level newborn indicators in African countries.
REFNo: HS2473ES

1. Map newborn indicator data availability in existing routine health information systems (RHIS) 2. Assess newborn key indicator data quality in existing RHIS. 3. Understand newborn indicator data use by different stakeholders in existing RHIS. 4. Analyse technical, organizational and behavioural enabling factors in RHIS to improve newborn indicator data quality and use 5. Measure the effect of the COVID-19 pandemic on newborn RHIS data
Uganda 2022-11-08 14:00:16 2025-11-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Francis Ekwan Uzu
ID: UNCST-2022-R009805
 Co-creating a Culturally Relevant Programme for Enabling Participation of Children with Brain Injury in Uganda (CEBU)
REFNo: HS2509ES

To explore the participants’ thoughts, feelings, and perceptions of the current intervention programme at the KWB-HTC.,To generate a culturally relevant programme (CRP) for enabling participation of children with brain injury in the KWB-HTC.,To describe the consequences and limitations of a CRP for children with brain injury in the KWB-HTC.,To describe how the participants co-create a Culturally Relevant Programme (CRP) enabling participation of children with brain injury in the KWB-HTC.,
 Uganda 2022-11-08 13:54:18 2025-11-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Godfrey  Siu
ID: UNCST-2021-R005439
 STRENGTHENING THE HEALTH SECTOR SYSTEMS WORKFORCE IN THE PREVENTION AND RESPONSE TO VIOLENCE AGAINST CHILDREN: A PILOT PROJECT IN MAYUGE AND AMURU DISTRICTS
REFNo: SS1497ES

3. To measure impact and key outcomes of these interventions on health worker knowledge, attitudes, and competences in VAC service improvement and delivery.,2. To deliver a package of VAC interventions that is realistic, relevant and acceptable to health workers, including leadership development, training, dissemination of existing guidelines and the use of lay workers as case advocates to provide basic information and escort survivors to various referral points.,1. To explore, both qualitatively and quantitatively, the knowledge, practices and attitudes towards VAC prevention and response work, services offered, roles and current capacities, and barriers to involvement. ,Our aim is to collaboratively design and test the acceptability, feasibility, and scalability of a health worker capacity building and leadership strengthening VAC intervention in Mayuge and Amuru districts in eastern and northern Uganda.,
 Uganda 2022-11-08 13:49:21 2025-11-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Mugagga Isaac
ID:
Empowerment Beyond the Household: Measuring and Comparing the Collective Agency of Groups and Individuals
REFNo: A194ES

a) Measure the degree to which group members and the group as a whole verbally express and/or behaviorally indicate a sense of collective agency
b)Identify features of groups and external factors, including targeted interventions, that can successfully increase women’s collective agency
c)Understand how intersectionality affects the ability of women and men of different backgrounds to participate in, and benefit from, group processes
d)Understand the impacts of increased collective agency in terms of outcomes for individual women and their groups
e)Better understand linkages between empowerment within and outside the household


 Uganda 2022-11-08 13:36:34 2025-11-08 Agricultural Sciences Non-Clinical Trial Non-degree Award
Andreas Madestam
ID:
Closing the gender Gap in Agriculture: Experimental Evidence from Uganda
REFNo: SS1360ES

To evaluate if the gender gap in agriculture productivity is caused by lack of soft skills among female farmers in Uganda.
 Sweden 2022-11-08 13:32:20 2025-11-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 A Phase II Multicenter Study of Pomalidomide Monotherapy in HIV-Positive Individuals with Kaposi Sarcoma (KS) in Sub-Saharan Africa (SSA)
REFNo: HS2367ES

To evaluate if changes in serum cytokine levels correlate with clinical response.,To assess the effect of pomalidomide treatment on serum cytokine levels.,To evaluate the effects of pomalidomide monotherapy on standard measures of HIV control, i.e., CD4 counts and HIV viral loads, in this participant population.,To determine if pomalidomide monotherapy induces a minimal level of antitumor efficacy to justify its further development for HIV-associated KS in sub-Saharan Africa and is safe and tolerable.,
 Uganda 2022-11-08 13:27:55 2025-11-08 Medical and Health Sciences Clinical Trial Non-degree Award
Simons  Ezajobo
ID: UNCST-2021-R012010
 Uptake of HIV Testing Services through Assisted Partner Notification (APN) among Men in Wakiso District.
REFNo: HS2537ES

2.To understand the preferred partner notification approaches to help men feel more comfortable and confident in getting tested for HIV.,1.To assess the experience of males during the process of HIV testing services provision.,To identify barriers and facilitators to HIV testing among men in Uganda,
 Uganda 2022-11-08 13:23:56 2025-11-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
 PHARMACOKINETICS OF DRUGS USED TO TREAT UNCOMPLICATED MALARIA IN BREASTFEEDING MOTHER-INFANT PAIRS
REFNo: HS2392ES

Primary Objectives;
1. To define transfer of lumefantrine and its active metabolite, desbutyl-lumefantrine from mother to breastfed infant.
2. To determine the clearance, AUC, and volume of distribution of lumefantrine and desbutyl-lumefantrine
Secondary Objectives
1. To describe covariates influencing drug exposure in maternal plasma, breast milk and infant plasma
2. To develop a population pharmacokinetic model including the breast and the infant as compartments, which will both enable optimal use of sparse data from future studies and enable simulations of different doses or combinations.
3. To assess depression and anxiety levels among breastfeeding mothers on first line antimalarial drugs.
4. Beliefs about medicines in breastfeeding mothers receiving antimalarial treatment



 UK 2022-11-04 16:05:41 2025-11-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
 Innovations for continuity of HIV, TB and malaria services during the COVID-19 pandemic in Uganda
REFNo: HS2477ES

The goal of this research is to collate and assess the impact of innovative people-centred and community-based approaches adopted during the covid-19 pandemic to ensure continued HIV, TB and malaria services in Uganda. This will inform the ongoing and future pandemic/epidemic response actions.
Specific objectives are:
1. To identify innovations used to mitigate the impact of the covid-19 pandemic on the provision, access, and utilization of HIV, TB and Malaria services in Uganda.
2. To assess the impact of innovations to mitigate the impact of the COVID-19 pandemic on HIV, TB, and Malaria services provision, access, and utilization.
3. To document the lessons learnt in innovating to mitigate the impact of COVID-19 on HIV, TB and malaria services in Uganda during the pandemic.

 Uganda 2022-11-03 12:21:51 2025-11-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Albert Munyeshyaka
ID:
Cosmological studies in modified Gauss-Bonnet gravity
REFNo: NS434ES

To determine evolution of overdensities and velocity perturbations in f (G) grav- ity,To analyse perturbations of a Chaplygin gas model in f (G) gravity,To analyse covariant velocity and overdensities of quasi-Newtonian cosmological model in f (G) gravity,To derive evolution of 1 + 3 covariant linear perturbation equations in f (G) gravity.,The aim of this study is to explore cosmological studies in modified Gauss-Bonnet gravity.,
 Rwanda 2022-11-03 12:09:30 2025-11-03 Natural Sciences Non-Clinical Trial Degree Award
MICHAEL JACKSON WAKWABUBI
ID:
Financial distress in local governments in Uganda
REFNo: SS1429ES

To establish the relationship between local government delivery system and financial distress in local governments in Uganda To assess the relationship between revenue concentration and financial distress in local governments in Uganda To examine the relationship between revenue concentration, local governance, corruption and LG delivery system in local governments in Uganda To assess the mediating effect of LG delivery system in the relationship between revenue concentration, local governance, corruption and financial distress in local governments in Uganda To establish the relationship between local governance and financial distress in local governments in Uganda To establish the relationship between corruption and financial distress in local governments in Uganda
Uganda 2022-11-03 11:38:10 2025-11-03 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 ‘Remdesivir: Monitored Emergency Use for Filoviral Disease’
REFNo: HS2531ES

To offer patients with laboratory-confirmed filovirus disease (e.g. Ebola virus [EBOV], Bundibugyo virus [BDBV], Marburg virus [MARV] disease, and Sudan virus [SUDV]) under the clinical supervision of the protocol Principal Investigator or their designated physicians, access to treatment with Remdesivir under monitored conditions.
Uganda 2022-11-02 17:30:52 2025-11-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 Efficacy, Safety and Effectiveness of Injectable Cabotegravir/Rilpivirine in Improving HIV Control in Sub-Saharan Africa: A pragmatic Phase 3 Open-label Randomized Controlled Trial.
REFNo: HS2475ES

Primary objective:
To demonstrate the non-inferior efficacy of switching to every 2 months (Q2M) intramuscular (IM) injection of cabotegravir (CAB) long acting (LA) plus rilpivirine (RPV) LA compared with continuation of first-line oral ART over 12 months in people living with HIV (PLHIV) with a history of, or at risk of, sub-optimal HIV control.

Secondary objectives:
1) To demonstrate the antiviral activity and the impact on retention in HIV care of switching to Q2M CAB LA + RPV LA compared with continuation of oral ART over 12 and 24 months in PLHIV with a history of, or at risk of, sub-optimal ART adherence or engagement in care.

2) To demonstrate the immunological activity of switching to Q2M CAB LA + RPV LA compared with continuation of oral ART over 12 and 24 months in PLHIV with a history of, or at risk of, sub-optimal ART adherence or engagement in care. This will be measured through change in CD4+ T cell count and incidence of HIV disease progression.

3) To evaluate the safety and tolerability of switching to Q2M CAB LA + RPV LA compared to continuation of oral ART.

4) To assess genotypic viral resistance in participants experiencing protocol-defined confirmed virological failure (plasma HIV-1 RNA >200 c/ml) and its impact on future treatment options including proportion who resuppress on dolutegravir.

5) To evaluate the effect of Q2M CAB LA + RPV LA on health-related quality of live, treatment satisfaction and treatment adherence. To describe cost-effectiveness and acceptability of the regimen.

Uganda 2022-11-02 17:27:11 2025-11-02 Medical and Health Sciences Clinical Trial Non-degree Award
Clare Bangirana Ahabwe
ID: UNCST-2021-R012842
 Violence Against Children and Youth Surveys (VACS) Cognitive Testing of Gender Attitude and Norm Measures Among Youths in Humanitarian Settings in Uganda
REFNo: SS1486ES

• To evaluate participants’ interpretation of the gender measures, consider and weigh relevant aspects of their lives and formulate a response based on those considerations.
• To test and refine gender measures that are understandable to 13-24-year-old study participants for inclusion in the core VACS questionnaire and future VACS administration.
• To identify context specific relevance of proposed gender measures in the administration of VACS in a humanitarian setting within Uganda.

Uganda 2022-11-02 10:14:05 2025-11-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Achilles Kiwanuka
ID:
Comparative Analysis of Health Information Systems Approaches in Use in Uganda
REFNo: HS2521ES

1. Describe the achievements, challenges, lessons learned and prospects for using the paper based HMIS, Smart Paper Technology and fully digitalized approaches for managing health information in Uganda.
2. Assess performance, usability and functionality of the fully digitalised and paper based HMIS approaches at the community level and Smart Paper Technology at the health facility level using the Performance of Routine Information System Management (PRISM) framework.
3. Analyze the cost benefit of using Smart Paper Technology and fully digitalised approaches of health information systems in Uganda.
4. Analyze the cost effectiveness of using Smart Paper Technology and fully digitalised approaches over the paper based HMIS for managing health information in Uganda.
5. Assess the impact on the budget after adopting Smart Paper Technology or fully digitalised approaches for managing health information with a focus to community health information systems in Uganda.
6. Evaluate the scalability of the Smart Paper Technology and fully digitalised approaches considering geographic scale and integration with other HMIS components

 Uganda 2022-11-01 18:27:02 2025-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Okee Margaret Jill
ID:
USING INFORMATION AND COMMUNICATION TECHNOLOGY FOR LEARNING ENHANCEMENT IN HIGHER EDUCATION INSTITUTIONS: CASE OF KAMPALA METROPOLITAN AREA
REFNo: SIR144ES

1.To determine the relationship between e-learning pedagogy and learning enhancement.
2.To determine the relationship between motivation of students and learning enhancement.
3.To determine the relationship between ICT systems characteristics and learning enhancement.
4.To determine the combined effects of the relations of e-learning pedagogy and ICT systems characteristics on motivation of students.
5.To determine the combined effects of the relationships of e-learning pedagogy, motivation of students and ICT characteristics on learning enhancement.
6.To establish the intermediating role of the e-learning policy between institutional support and learning enhancement.
 Uganda 2022-10-31 15:34:11 2025-10-31 Engineering and Technology Non-Clinical Trial Degree Award
Charles Drago Kato Drago
ID: UNCST-2021-R012897
 Development and evaluation of a community-based bat-human interface monitoring program for zoonotic spillover early warning and response in Uganda
REFNo: HS2428ES

1) To build a community-created map of bat-human interfaces in Bundibugyo.
2) Establish an ecological baseline on the bats and human- bat interactions in Bundibugyo district
3) Establishing a sustainable bat-human interface monitoring program
 Uganda 2022-10-31 15:31:18 2025-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dr. Betty Kwagala
ID: UNCST-2022-R009048
 Economic and Health impact and the resilience of last mile populations in artisanal and small- scale mining unplanned settlements in Sub-Saharan Africa before, during and after COVID-19: The case of Ghana and Uganda
REFNo: SS1496ES

4) To identify, co-develop and pilot test one context specific priority intervention to strengthen last mile adolescent girls’ resilience during future crises,3) To describe the interventions proposed by these populations and literature for strengthening adolescent girls’ coping skills and fostering resilience during the COVID-19 pandemic recovery and their applicability to future crises,2) To identify the coping mechanisms adolescent girls used to support their health and economic wellbeing during the pandemic.,1) To assess the economic and health impacts of the COVID-19 pandemic on the last-mile adolescent girls living in unplanned mining communities in Uganda and Ghana. To describe and assess the economic, health impacts and the resilience of adolescent girls in unplanned mining communities and coping mechanisms during the COVID-19 pandemic to support their future resilience and ability to cope during recovery and in similar future crises.
Uganda 2022-10-28 15:09:30 2025-10-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 A randomized, double-blind, positive-controlled Phase III clinical trial to evaluate the efficacy and safety of SCTV01E (A COVID-19 Alpha/Beta/Delta/Omicron Variants S-Trimer Vaccine) in population previously unvaccinated with COVID-19 vaccine and aged ≥18 years
REFNo: HS2508ES

To evaluate the protective efficacy of SCTV01E against symptomatic COVID-19 occurring from 14 days after the 2nd dose in population
previously unvaccinated with COVID-19 vaccine.


To evaluate the protective efficacy of SCTV01E against symptomatic COVID-19 occurring from 7 days after the 3rd dose in population previously unvaccinated with COVID-19 vaccine
 Uganda 2022-10-28 15:05:42 2025-10-28 Medical and Health Sciences Clinical Trial Non-degree Award
DAVID KITYA
ID: UNCST-2022-R009620
 ASSESSMENT OF NEURAL TUBE DEFECTS AMONG NEWBORNS IN UGANDA: A STUDY OF PREVALENCE, RISK FACTORS, AND THE ROLE OF GENE-ENVIRONMENTAL INTERACTIONS (NTDS IN UGANDA)
REFNo: HS2479ES

Determine the proportion of newborns with neural tube defects.
2. Assess the correlation of common NTD risk factors in the development of NTDs.
3. Evaluate the environmental-gene interactions in the development of NTDs.

 Uganda 2022-10-28 13:30:38 2025-10-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 AMC-104, Feasibility study of ocular surface squamous neoplasia (OSSN) surgical excision in people living with HIV in sub-Saharan Africa (SSA)
REFNo: HS2366ES

To assess the feasibility of conducting multi-center prospective studies on surgical excision of suspected OSSN lesions in SSA in people living with HIV/AIDS (PLWHA).,
 Uganda 2022-10-28 13:28:27 2025-10-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clovice Kankya
ID: UNCST-2020-R010154
 Capacitating One Health in Eastern and Southern Africa (COHESA)
REFNo: SS1482ES

To understand One Health performance, capacity, and bottlenecks within Uganda,To understand Current One Health Research and Innovation within Uganda,To understand One Health challenges, gaps and capacities within Uganda,
 Uganda 2022-10-27 9:26:54 2025-10-27 Social Science and Humanities Clinical Trial Non-degree Award
EDITH  NAKKU-JOLOBA NAKKU
ID: UNCST-2021-R013931
 MULT-COUNTRY AETIOLOGY OF GENITAL ULCER STUDY
REFNo: HS2498ES

To determine the prevalence of other sexually transmitted infections in individuals with GUD,To assess the Aetiology of genital ulcer diseases in Low and Middle Income Countries.,
 Uganda 2022-10-27 7:52:03 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 STANDARD i-Q COVID-19 Ag Home Test - Laymen study including Usability.
REFNo: HS2511ES

The objective of this laymen study is to establish the usability of the STANDARD i-Q COVID-19 Ag Home Test in a self-testing environment. More specifically, the study will assess whether the instructions for use and labels are clear and understandable and whether the test can be performed correctly by laypersons.,
 Uganda 2022-10-27 7:48:55 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Daniel Kibuuka Musoke
ID: UNCST-2021-R011749
 Survey Protocol Zone of Influence Survey Uganda 2022 Feed the Future Phase Two Zone of Influence and Resilience Focus Zone Midline Indicator Assessment
REFNo: A232ES

The Midline Survey will collect primary data to generate estimates for a total of 25 indicators—14 Feed the Future P2-ZOI indicators, plus a new indicator on water security, and 10 RFZ indicators, which will only be collected in the RFZ. ,
 Uganda 2022-10-27 7:38:03 2025-10-27 Agricultural Sciences Non-Clinical Trial Non-degree Award
David Musoke
ID:
Experiences of Village Taskforce members and Community Health Workers in COVID-19 prevention and control in Uganda
REFNo: HS2502ES

To assess the experiences of village task force members and community health workers (CHWs) in response to COVID-19 so as to provide information to strengthen community response to the pandemic in Uganda.
Uganda 2022-10-27 7:35:53 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Clara HOZER
ID: UNCST-2022-R010004
 Inter-individual variation in sleep strategies and consequences for fitness and cognition in wild chimpanzees (Pan troglodytes)
REFNo: NS433ES

- To assess whether chimpanzees display inter-individual variation in sleep strategies
- To determine if these strategies are driven by endogenous and social factors
- To explore if these sleep strategies have specific fitness consequences
- To investigate if these sleep strategies are in a trade-off relation with cognitive performance

 France 2022-10-27 7:33:37 2025-10-27 Natural Sciences Non-Clinical Trial Degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 Feasibility, Usability and Acceptability of stool-based qPCR to diagnose TB in children aged up to 8-years and HIV- positive adults in Mozambique, Eswatini and Uganda: a qualitative study
REFNo: SS1492ES

To identify cultural, socioeconomic and health system barriers and facilitators to the diagnostic tool’s implementation and uptake,To assess healthcare professionals’ perception of usefulness and applicability and related factors,To assess patients’ compliance and satisfaction with the intervention,To assess the participants’ (caretakers and PLWHA)/health professionals’ interpretation of a procedure involving stool collection for TB diagnosis in the light of current information, education communication messages regarding TB transmission,To describe participants’ views on, experiences with, and reactions towards the intervention,To explore participant’s perceptions and attitudes regarding TB in general and diagnosis in particular,To assess the feasibility of stool-based TB diagnostics from the healthcare professionals, patients and caregiver’s perspective in Uganda, Eswatini and Mozambique,
 Uganda 2022-10-27 7:29:40 2025-10-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paul Kiptis Kipyator
ID:
PITYRIASIS ROSEA: PREVALENCE, CLINICAL VARIANTS, AND DERMOSCOPIC FEATURES AMONG PATIENTS ATTENDING THE SKIN CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL, UGANDA
REFNo: NS435ES

To describe the dermoscopic features of Pityriasis rosea at MRRH Skin clinic.,To describe the clinical variants of Pityriasis rosea at MRRH Skin clinic.,To determine the prevalence of Pityriasis rosea at MRRH Skin clinic.,To determine the prevalence, clinical variants, and dermoscopic features of Pityriasis rosea among patients attending the Skin clinic at MRRH.,
 Kenya 2022-10-27 7:26:09 2025-10-27 Natural Sciences Non-Clinical Trial Degree Award
Allison Ross
ID:
Behavioral Nudges to Encourage Appropriate Antibiotic Use Among Health Professionals in Uganda
REFNo: HS2429ES

Collect immediate post-intervention and follow up data to analyze and assess the short- and medium-term impact of the behavioral intervention. Implement the behavioral intervention developed in Phase II to impact prescribing behaviors. Develop a culturally appropriate behavioral intervention based on findings from Phase I. Gain an improved understanding of the cultural context around prescriptions in Ugandan hospitals to inform intervention development. Additionally, collect baseline data on prescribing behaviors among staff. Increase adherence to national antibiotic prescribing guidelines among hospital-based health care providers in Uganda by implementing a behavioral “nudge” intervention, contributing to the containment of AMR in the country.
 USA 2022-10-27 7:21:19 2025-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jordan Lwanga Byekwaso
ID:
Towards an inclusive higher education for non-traditional students in Uganda
REFNo: SS1458ES

4) To develop a model of teaching-learning strategies that Makerere University can use to support learners to succeed in rapidly changing learning and working environments,3) To explain the different opportunities that the enrollment and participation of NTS at Makerere University provide to re-align HE systems and practices for inclusivity,2) To explain the different understandings of the central meaning of NTS’s return for higher education at Makerere University ,1) To establish an understanding of what Makerere University conceptualises as the target and purpose of widening access routes for its admission for undergraduate studies,
 Uganda 2022-10-25 5:14:45 2025-10-25 Social Science and Humanities Non-Clinical Trial Degree Award
Derrick Mimbe Emmanuel
ID:
Evaluate the existing Digital Tools to support COVID-19 response in Uganda
REFNo: SIR140ES

Provide recommendation on performance and use of existing digital tools including ODK, mTrac, and RDS applications to improve results dispatching, contact tracing, and case reporting., Evaluate existing COVID-19 digital tools to understand their core determinants and their operational usability and acceptability among key end-users to improve the COVID-19 response in Uganda.,
 Uganda 2022-10-25 5:13:07 2025-10-25 Engineering and Technology Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Extension of SEARCH SAPPHIRE Dynamic Choice Prevention Study
REFNo: HS2447ES

To compare biomedical prevention coverage achieved using a Dynamic prevention model that includes a patient-centered CAB-LA delivery intervention to biomedical prevention coverage under the standard of care over 48 weeks.

Secondary Objectives: To determine the reach, effectiveness, adoption, implementation and maintenance of a patient-centered CAB-LA program embedded in 3 ongoing trials in the setting of antenatal clinic, outpatient clinic, and community.

Tertiary Objectives: To evaluate change in knowledge, awareness and acceptability/satisfaction at the staff and provider level with CAB-LA before and after provider and staff training and education in CAB-LA with patient-centered delivery model.


 Uganda 2022-10-25 15:31:11 2025-10-25 Medical and Health Sciences Clinical Trial Non-degree Award
Terence Odoch
ID: UNCST-2022-R010584
 AN EXPLORATIVE INVESTIGATION TO IDENTIFY ECONOMIC, BEHAVIOURAL, SOCIO-CULTURAL AND GENDER-BASED RISK FACTORS FOR DISEASE SPILLOVER AT BAT-HUMAN INTERFACE IN BUNDIBUGYO, UGANDA
REFNo: HS2472ES

To explore the community behavioural, socio-cultural and gender-based factors that contribute to increased risk of human-bat interaction,To describe local knowledge and beliefs about bat species, risks, and benefits,To explore and document economic, behavioral, socio-cultural and gender-based risk factors that expose and enhance spillover of zoonotic disease pathogens at bat-human interface,To determine the level of bat-human interaction in Bundibugyo district by age and gender,
 Uganda 2022-10-25 14:56:35 2025-10-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Angelina Kakooza-Mwesige
ID: UNCST-2020-R014529
 Epilepsy in Uganda: Clinical characterization and co-morbidities, their relation to stigma among adolescents and impact of a community-based engagement program. (AWE Change project) REF: TASO-2022-102
REFNo: HS2421ES

1.TO CLINICALLY CHARACTERIZE EPILEPSY AND ITS IMPACTS AMONG CHILDREN AND ADULT CASES IN UGANDA. 2.DESCRIBE THE MAGNITUDE, DRIVERS, AND IMPACT OF EPILEPSY-RELATED STIGMA ON ADOLESCENTS IN UGANDA. 3.TO CO-CREATE AND EVALUATE THE IMPACT OF A COMMUNITY-BASED ENGAGEMENT PROGRAM TO REDUCE STIGMA ON EPILEPSY AMONG ADOLESCENTS IN UGANDA.
 Uganda 2022-10-25 14:54:28 2025-10-25 Medical and Health Sciences Clinical Trial Non-degree Award
JULIET SSEMATIMBA
ID:
INDIGENOUS SALT MAKING TECHNOLOGY AT KIBIRO SALT GARDENS IN BUNYORO 1894-2015.
REFNo: SS1450ES

The main objective of the study is to investigate and discuss the historical trends of indigenous salt making technology , its persistence and how that shapes the gender relation at kibiro salt gardens.
 Uganda 2022-10-21 17:04:00 2025-10-21 Social Science and Humanities Non-Clinical Trial Degree Award
Jemimah Kyeyune Kiboss
ID: UNCST-2021-R013163
 Prevalence of Metabolic Syndrome and Associated Factors Among Corporate Company Employees in Uganda
REFNo: HS2098ES

III. To determine the lifestyle factors associated with metabolic syndrome among corporate company employees in Kampala.,II. To identify individual factors associated with metabolic syndrome among corporate company employees in Kampala.,I. To assess the prevalence of metabolic syndrome among corporate employees in Kampala.,The main aim of this study will be to evaluate the prevalence of metabolic syndrome and its associated factors among corporate company employees in Kampala, Uganda.,I. To assess the prevalence of metabolic syndrome among corporate employees in Kampala. II. To identify individual factors associated with metabolic syndrome among corporate company employees in Kampala. III. To determine the lifestyle factors associated with metabolic syndrome among corporate company employees in Kampala.,
 Kenya 2022-10-21 17:01:28 2025-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Opondo
ID: UNCST-2022-R010446
 A Monitoring and Evaluation of Managing Animal Health and Acaricides for a Better Africa (MAHABA): A landscaping study in Uganda
REFNo: A233ES

Assess protocols selected in controlling ticks and tickborne diseases, Assess acaricide availability to the farmers ,Assess extent of farmer observed acaricide resistance and treatment failures, Determine farm size and management systems of farmers, Determine the number and proportion of farmers using acaricides ,Assess other production constraints among farmers ,Assess the cost controlling of ticks and tick borne diseases among farmers, Assess farmers practices, knowledge, perceptions, attitudes and challenges on use of acaricide products for cattle in the control of Ticks and tickborne diseases in selected districts of Uganda with high burden of ticks and tickborne diseases, Assess the role of gender in ticks and tick borne disease management, Assess opportunities for developing new routes for communication, Determine sources of information on acaricides, ticks and tickborne diseases
 Uganda 2022-10-21 14:11:50 2025-10-21 Agricultural Sciences Non-Clinical Trial Non-degree Award
Fredrick Kabi
ID:
EVALUATION OF THE SAFETY, EFFICACY AND EFFECTIVENESS OF THE SUBOLESIN BASED ANTI-TICK VACCINE: A RANDOMISED DOUBLE BLINDED MULTI-SITE CONFINED FIELD TRIAL
REFNo: A191ES

OVERALL OBJECTIVE
Evaluation of the Safety, Efficacy and Effectiveness of Subolesin based Anti-tick Vaccine for control of ticks naturally infesting different cattle breeds under confined field conditions in Uganda.

SPECIFIC OBJECTIVES
I. To determine the safety of the injectable Subolesin based Anti-tick vaccine for control of tick infestations under natural confined field conditions.
II. To determine the efficacy of the injectable Subolesin based Anti-tick vaccine for control of tick infestations under natural confined field conditions.
III. To determine the effectiveness of the injectable Subolesin based Anti-tick vaccine for control of tick infestations under natural confined field conditions.

 Uganda 2022-10-21 12:58:12 2025-10-21 Agricultural Sciences Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 A Phase Ib trial to evaluate the safety and immunogenicity of R21/Matrix-MTM in African children living with HIV.
REFNo: HS2496ES

Primary objective a) To assess the safety and reactogenicity profile of the malaria vaccine candidate R21/Matrix-MTM in 5-36-month-old African children living with HIV Secondary objectives a) To assess the humoral immunogenicity of R21/Matrix- MTM in 5-36-month-old African children, comparing children living with HIV with HIV negative children b) To assess the impact of vaccination on HIV reservoir c) To assess whether increasing age and nadir CD4 count are associated with immunogenicity of R21/Matrix-MTM in 5-36- month-old African children living with HIV Tertiary objectives a) To assess the immunogenicity profile of R21/Matrix-MTM in 5- 36-month-old African children, comparing children living with HIV with HIV negative children
 Uganda 2022-10-20 18:13:49 2025-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Rukundo NSHAKIRA
ID: UNCST-2021-R012277
 Humanitarian Aid and Refugee Self-reliance
REFNo: SS1470ES

The overall objective of this study is to evaluate the impact of each of the interventions (see protocol) on selected socioeconomic and psychological wellbeing outcomes ,What are the mechanisms through which the interventions affect the primary and secondary outcomes? ,Which intervention is the most cost-effective in helping refugees improve their primary and secondary outcomes?,What is the impact of the interventions on school attandance and performance, aspirations and future orientation and self esteem and remittances (secondary outcomes),What is the impact of each if the interventions on economic prosperity, psychological wellbeing and ability to cope with adversity? (primary outcomes),
 Uganda 2022-10-20 18:11:16 2025-10-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Proscovia Namuwenge Mukonzo
ID:
Assessing causes of mortality and loss to follow-up among people living with HIV in Uganda
REFNo: HS2499ES

To examine causes of death contributing to mortality among PLHIV. ,To describe the reasons patients discontinue treatment and no longer remain active in care.,
 Uganda 2022-10-20 18:07:40 2025-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Kalyesubula
ID:
Human-centered design to adapt and inform an integrated chronic disease management program in Uganda using mobile payment services. (Acronym: IMPEDE CVD)
REFNo: HS2445ES

1)To understand patient and provider perspectives on the potential and acceptability of financing schemes and mHealth interventions aimed at strengthening behavior in relation to ideal drug availability and uptake among NCD patients (Work Package (WP) 1a).
2)To develop together with end-users a prototype for a mobile phone-based solution (including mobile-based nudges) to increase the availability and uptake of NCD drugs (WPs 1b, and 2).
3)To test the prototype, establishing proof of concept, and to assess end-users’ experiences interacting with two versions of the prototype (comparing two saving models), including how users make and evaluate payment management decisions, in preparation for a subsequent study (WP 3).
 Uganda 2022-10-20 18:01:35 2025-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
James Hintson
ID: UNCST-2022-R010009
 Service Delivery and Public Infrastructure in Northern Uganda
REFNo: SS1476ES

The primary objective of the study is to describe and explain increases in service delivery, public infrastructure, and state-society interactions in Northern Uganda over time. The secondary objectives are to document community leaders’ satisfaction with the expansion of service delivery and public infrastructure construction, and to validate a separately collected dataset on public infrastructure throughout sub-Saharan Africa over time, as derived from satellite imagery.
 USA 2022-10-19 10:58:32 2025-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Lydia Nakiyingi
ID: UNCST-2022-R010102
 Understanding the impact of COVID-19 on women in the global healthcare workforce: a mixed methods study
REFNo: HS2415ES

To describe the impact of COVID-19 on female HCWs in resource-limited settings

To explore and contextualize the impact of COVID-19 on female healthcare workers to inform implementation of interventions to decrease female HCWs’ burden



 Uganda 2022-10-19 10:55:07 2025-10-19 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MIRIAH KEMIGISHA
ID: UNCST-2022-R009927
 VACCINE WASTAGE: THE MAGNITUDE, CAUSES AND ASSOCIATED FACTORS IN HEALTH FACILITIES OF RUKUNGIRI DISTRICT, SOUTH WESTERN UGANDA.
REFNo: HS2406ES

General Objective To determine the magnitude of vaccine wastage when immunizing infants, its causes and associated factors in health facilities of Rukungiri District, South Western Uganda. Specific Objectives. 1)- To determine the wastage rates of the different vaccines used in immunizing infants in health facilities of Rukungiri District, South Western Uganda. 2)-To identify the common causes of vaccine wastage when immunizing infants in health facilities of Rukungiri District, South Western Uganda. 3)-To explore the factors associated with vaccine wastage when immunizing infants in health facilities of Rukungiri District, South Western Uganda
Uganda 2022-10-19 10:51:20 2025-10-19 Medical and Health Sciences Non-Clinical Trial Degree Award
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