Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Gloria Kirungi Kasozi Kasozi
ID:
School-Based Sexual and Reproductive Health Services for Prevention of Adolescent Pregnancy in Hoima District, Uganda: a cluster randomized controlled trial
REFNo: HS247ES

1. To investigate the effect of School Based SRH services on occurrence of adolescent pregnancy among school girls aged 15-19 years in Hoima District, Uganda. 2. To evaluate the effect of School Based SRH services on sexual behavioral change for prevention of adolescent pregnancy among school girls aged 15-19 years in Hoima District, Uganda. 3. To analyze the effect of School Based SRH services on utilization of SRH services among school girls aged 15-19 years in Hoima District, Uganda. 4. To develop a School Based SRH services model for the prevention of adolescent pregnancy among school girls in Uganda
Uganda 2018-11-30 2021-11-30 Medical and Health Sciences Degree Award
BOSCO AGABA BEKIITA
ID: UNCST-2019-R000549
Molecular Epidemiological Surveillance of pfhrp2 and pfhrp3 Gene Deletions in Plasmodium falciparum Parasite Population in Uganda
REFNo: HS271ES

(i) To determine prevalence of pfhrp2/3 gene deletions in P. falciparum parasites in Uganda. (ii) To determine the distribution and geographical spread of pfhrp2/pfhrp3 gene deletions in P. falciparum parasites in Uganda. (iii) To determine the factors associated with pfhrp2/pfhrp3 gene deletions in P. falciparum parasites in Uganda. (iv) To determine diagnostic accuracy of malaria RDTs as compared to blood smear microscopy and PCR in settings where there are pfhrp2/pfhrp3 gene deletions in Uganda. (v) To determine the multiplicity of infections in P. falciparum strains with pfhrp2/ pfhrp3 gene deletions in Uganda. (vi) To determine the genetic diversity of P. falciparum Histidine-Rich Protein-2/3 genes in Parasite populations in Uganda. (vii) To determine the origin and relatedness of pfhrp2/pfhrp3 gene deleted P.falciparum strains in Uganda.
Uganda 2018-11-30 2021-11-30 Medical and Health Sciences Degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
One Dollar Incentive to Improve Tuberculosis Treatment Outcomes in a Programmatic Setting (ODITOPS trial)
REFNo: HS254ES

Primary objectives: 1. To determine the effect of a one dollar incentive on the TB treatment success rate of patients receiving TB treatment in rural hospitals of Uganda and Kenya. 2. To determine the effect of a one dollar incentive on TB loss to follow up rate of patients receiving TB treatment at rural hospitals in Uganda and Kenya Secondary Objectives: 1. To determine the effect of a one dollar incentive on TB death rate of TB patients receiving TB treatment at rural hospitals in Uganda and Kenya. 2. To evaluate the impact of a one dollar incentive on the TB treatment failure rate of TB patients receiving TB treatment at rural hospitals in Uganda and Kenya
Uganda 2018-11-13 2021-11-13 Medical and Health Sciences Non-degree Award
Hindum Lanyero
ID:
Monitoring antibacterial use in children under five in rural Communities of northern Uganda.
REFNo: HS235ES

General Objective To investigate antibacterial use among children under five in rural communities of northern Uganda and develop a method that can be used to validate the reported use. Specific objectives 1. To determine antibacterial medicine use patterns as reported by caregivers of children under five who present with symptoms of acute respiratory tract infections and/or diarrhea in rural communities of northern Uganda (sub-study I). 2. To develop a chromatographic method for simultaneous identification of multiple antibacterial medicines in whole blood and urine spotted on filter paper (Sub-study II). 3. To establish the validity of self-reports in monitoring antibacterial use in children under five who are brought to health facilities with symptoms of acute respiratory tract infections and/or diarrhea in rural communities of northern Uganda (sub-study III)
Uganda 2018-11-06 2021-11-06 Medical and Health Sciences Degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
Pictures of ageing in Uganda: A pilot study to explore demography, healthy ageing phenotype and self-perception in a community of older people in Uganda
REFNo: SS246ES

Primary objective: To determine the feasibility of combining demographic, phenotypic and artistic methods in understanding the picture of Ageing of community dwelling elderly individuals in Uganda. Secondary objectives: 1) To assess the accuracy of age-reporting among older people (>60 years) living in a Wakiso District community and investigate how the accuracy of age-reporting is linked to health, capabilities, social status and residential circumstances. 2) To pilot test data collection tool for demographic assessment of older people in Uganda (culturally, linguistically, historically appropriate). 3) To pilot test data collection tools for phenotypic assessment of older people in Uganda (health status, frailty, cognition, capabilities, quality of life, co-morbidities including HIV, access to health and other services). 4) To assess feasibility and acceptability of undertaking cognitive testing using electronic tablets in older people living in a Wakiso District community. 5) To assess feasibility and acceptability of engaging older people through visual / performing arts activities. 6) To explore perceptions and attitudes to a community based participatory research in older people building on discussions/ interviews conducted in the context of 1-4 above. 7) To develop an exhibition of artwork by established artists and older people to express their perceptions of older age.
Uganda 2018-11-06 2021-11-06 Social Science and Humanities Non-degree Award
Sarah Baliddawa
ID:
Household members’ role and experiences during MDR-TB patients care at Mbarara Regional Referral Hospital, Uganda
REFNo: HS253ES

General objective:  To explore the roles and experiences of household members during the care of MDR-TB patients attending MRRH Specific objectives:  To explore household members’ definition of MDR-TB  To explore the roles played by household members in care of MDR-TB patients  To explore the experiences of household members during care of MDR-TB patients
Uganda 2018-11-06 2021-11-06 Medical and Health Sciences Degree Award
Nelson TING
ID:
Genetic identity of elephant migrants across a forest-savanna mosaic of protected areas in Western Uganda
REFNo: NS72ES

To generate baseline knowledge of elephant movement, habitat use, and population size in and among the forested protected areas of western Uganda.
USA 2018-10-30 2021-10-30 Natural Sciences Non-degree Award
Proscovia Nabunya
ID: UNCST-2019-R000970
Social Support Systems and Community Resource Utilization for Children and Families Affected by HIV/AIDS in Uganda: A Stakeholder Perspectives Study.
REFNo: SS182ES

The overall aim of this research is to examine the social support systems and community resources available to orphaned children and families affected by HIV/AIDS in Southwestern Uganda. Specifically, utilizing a stakeholder perspective, the objectives of this research are: 1) To identify and examine the available social support systems and resources available to children and families affected by HIV; 2) To examine both family-level and community-level facilitators and barriers to access and utilization of community resources; and 3) To identify resource gaps and ways to improve social support systems for children and families affected by HIV. The long-term goal of this proposed research is to inform a developmental research grant application (R21), to test the feasibility, acceptability, and preliminary impact of a social support intervention that can address HIV-related stigma and social isolation, and its impact on the overall social and health wellbeing of orphaned children and their caregivers.
Uganda 2018-10-30 2021-10-30 Social Science and Humanities Degree Award
James Ssuuna
ID:
EFFECT OF HABITAT DISTURBANCE ON POPULATION DYNAMICS AND COMMUNITY STRUCTURE OF RODENTS IN MABIRA CENTRAL FOREST RESERVE, UGANDA
REFNo: NS73ES

1.Assess rodent composition, diversity, and habitat association in undisturbed forest, disturbed forest, and adjacent agricultural/fallow fields in Mabira central forest reserve(MCFR). 2.Determine the influence of habitat structure/disturbance, and seasonal changes on recruitment, and survival of the dominant rodent species in MCFR. 3.Determine the effect of habitat structure/disturbance, and rainfall patterns on the breeding/reproduction patterns of the dominant rodent species in MCFR. 4.Investigate the movement and ranging patterns of the dominant rodent species in MCFR.
Uganda 2018-10-30 2021-10-30 Natural Sciences Degree Award
Sadic Waswa Babyesiza Waswa
ID: UNCST-2019-R000849
PREVALENCE AND DIVERSITY OF HEAMOFLAGELLATES AND FILARIAL WORMS IN RODENTS AND SHREWS INHABITING A DEGRADATION GRADIENT IN MABIRA FOREST RESERVE
REFNo: NS54ES

•Investigate the rodent and shrew species composition and seasonal fluctuations in their population structures along a habitat degradation gradient in MCFR •Identify and describe heamoflagellates and filarial worms in rodents and shrews using their morphological, morphometric and molecular characteristics. •Describe diversity, prevalence, distribution and public health importance of heamoflagellates and filarial worms identified in rodents and shrews of MCFR. •Investigate factors that affect prevalence and distribution of heamoflagellates and filarial worms in rodents and shrews in MCFR. •Investigate the relationship between rodent borne zoonotics prevailing with in adjacent communities Vs heamoflagellates and filarial worms identified in rodents and shrews.
Uganda 2018-10-30 2021-10-30 Natural Sciences Degree Award
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