Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
NICHOLAS BARI NDAHURA BARI
ID:
EFFECTIVENESS OF NUTRITION EDUCATION ON GLYCAEMIC CONTROL IN PEDIATRIC TYPE 1 DIABETES MELLITUS PATIENTS IN UGANDA
REFNo: HS186ES

1. To assess the level of knowledge of nutrition management of T1DM among caregivers of T1D children (3-12 years) at selected T1DM clinics in Uganda. 2. To determine the dietary intake and adequacy of T1D children (3-12 years) at selected T1DM clinics in Uganda. 3. To develop a nutrition education training module for caregivers and T1D children (3-12 years) at selected T1DM clinics in Uganda. 4. To determine the effectiveness of nutrition education on HbAlc levels, knowledge of nutrition management of T1DM and dietary practices among caregivers and T1D children (3-12 years) at selected T1DM clinics in Uganda.
Uganda 2019-04-30 2022-04-30 Medical and Health Sciences Degree Award
Isaac  Kimbowa
ID:
ANTIMICROBIAL STEWARDSHIP PRACTICES AND QUALITY OF ANTIBACTERIAL USE IN CHILDREN UNDER-FIVE IN SELECTED HEALTH FACILITIES IN UGANDA
REFNo: HS339ES

1. To determine the structure and functional roles of MTCs in optimizing antibacterial use in management of childhood infections in under-five children in selected RRHs and PNFP health facilities in Uganda (sub-study I).
2. To determine stewardship practices guiding optimizing antibacterial use in management of infections in under five children in selected Health facilities in Uganda (sub-study II)
3. To determine extent of off-label and unlicensed use of antibacterial among children -five in paediatrics wards of selected RRHs and PNFPs in Uganda (Study III)
4. To determine the extent of antibacterial exposure to neonates during perinatal period among women delivering in selected regional referral hospitals in Uganda (Study IV).

Uganda 2019-04-24 2022-04-24 Medical and Health Sciences Degree Award
Julia Downing
ID:
Children’s, Adults and Health Professionals Understanding Illness, Death and Dying in Uganda
REFNo: HS276ES

The study aims to gain an understanding of children, adults and health professionals understanding of illness, death and dying in order to inform the provision of palliative care services in Uganda. The objectives of the study are to understand the following questions: I. What are Ugandan adults understanding of illness, death and dying? II. What are Ugandan children’s understanding of illness, death and dying? III. What is the understanding of Ugandan health professionals with regards to illness, death and dying?
UK 2019-04-16 2022-04-16 Medical and Health Sciences Non-degree Award
Adam Hewitt Smith
ID: UNCST-2019-R001658
A cluster randomised trial to determine whether increased postoperative surveillance of adult African surgical patients reduces postoperative mortality
REFNo: HS298ES

Primary objective - To determine whether increased postoperative surveillance reduces in-hospital mortality in high-risk adult surgical patients aged 18 years and over in Africa. Primary outcome measure - In-hospital mortality, censored at 30 days if the patient is still alive and in-hospital. Secondary objective - To determine whether increased postoperative surveillance reduces the incidence of the composite of severe in-hospital complications and mortality in high-risk adult surgical patients aged 18 years and over in Africa. Secondary outcome measure - Composite of severe in-hospital complications and mortality, censored at 30 days if the patient is still alive and in-hospital.
UK 2019-04-16 2022-04-16 Medical and Health Sciences Non-degree Award
miriam nantamu
ID:
Biosciences in nursing education: assessment of the level of explicit knowledge on antibiotic resistance (ABR) among preregistration nursing students in Uganda.
REFNo: HS313ES

Specific objectives
1. To assess the current level of knowledge on ABR among 3rd and 4th year nursing pre-registration nursing students in Uganda.
2. To identify the factors associated with the current level of bioscience knowledge among 3rd and 4th year pre-registration nursing students in Uganda.

Uganda 2019-04-16 2022-04-16 Medical and Health Sciences Degree Award
Sabine Haller
ID:
Species Identification of Non-Tuberculous Mycobacteria in the Ugandan Population
REFNo: HS330ES

Primary Objective:
To describe the non-tuberculous mycobacteria (NTM) species isolated in the Ugandan population.
Secondary Objective:
To describe patient characteristics and outcomes.

Switzerland 2019-04-16 2022-04-16 Medical and Health Sciences Non-degree Award
Anna Agnes Ojok Arach
ID:
Perinatal death: risk factors, postpartum depression, lived experiences and cultural perspective in lira, Uganda
REFNo: HS356ES

The study has the following objectives:

1. To determine the incidence and risk factors of perinatal deaths in Lira,

2. To examine the association between perinatal death and postpartum depression among women in Lira,

3. To describe the lived experience of women and partners who experienced perinatal death in Lira

4. To explore the cultural perspective of the Lango community on perinatal death.

Uganda 2019-04-16 2022-04-16 Medical and Health Sciences Degree Award
Prof. Dr. med. Hans Konrad Biesalski
ID:
Dietary Intake and Nutritional Situation of Women of Reproductive Age (20-50 Years Old) in Lango Sub-Region of Northern Uganda: Implementation of Calculator for Inadequate Micronutrient Intake (CIMI) Program
REFNo: HS319ES

The main objective of this study is to assess the dietary intake and nutritional status of women of reproductive age in the predominantly rural North of Uganda. Therefore, the innovative
nutrition software called Calculator for Inadequate Micronutrient Intake (CIMI) will be used and validated with the obtained data.

Research objectives:
(1) To evaluate the dietary intake and nutritional status of women of reproductive age (20-50 years old) from Lango Sub-Region in Northern Uganda.
(2) To adapt CIMI program to the country Uganda and to compare CIMI with the software NutriSurvey for its ability to analyze dietary nutrients intake (Fe, Zn and Vitamin A and protein) and energy content in the study region. For the validation of CIMI, a new localization (appropriate to Ugandan Food) will be implemented in the nutrition software before.
(3) To identify the main causes of poor food consumption patterns of Ugandan women of reproductive age.
Germany 2019-04-03 2022-04-03 Medical and Health Sciences Degree Award
Nasur Buyinza
ID:
NURSE - LED INTEGRATED PALLIATIVE CARE FOR MULTI DRUG RESISTANT TUBERCULOSIS PATIENTS TAKING ANTI MULTI DRUG RESISTANT TB THERAPY IN UGANDA – A RANDOMIZED CONTROLLED TRIAL
REFNo: HS275ES

I.To determine health professionals’ views on an appropriate model of integrated palliative care for MDR TB patients and their families alongside TB treatment II.To model a feasible integrated palliative care intervention for MDR TB using staff views and existing literature III.To test the effectiveness of the new model as compared to existing care in an RCT design IV.To determine patients’ post intervention perceived mechanism of action V.To identify a minimum palliative care package for MDR TB patients
Uganda 2019-04-03 2022-04-03 Medical and Health Sciences Non-degree Award
David Meya Bisagaya
ID: UNCST-2019-R000837
Single dose liposomal amphotericin for asymptomatic cryptococcal antigenemia (ACACIA)
REFNo: HS284ES

Study Objectives Primary Objectives: 1. To assess 24-week efficacy of single dose liposomal amphotericin in the treatment of asymptomatic cryptococcal antigenemia for meningitis-free survival. Secondary Objectives: 1 . To determine safety and tolerability of single-dose liposomal amphotericin for the treatment of asymptomatic cryptococcal infection. 2- To determine 24-week survival in those who receive the intervention compared to those who receive standard of care. 3. To evaluate cost and cost-effectiveness of single dose liposomat amphotericin for the treatment of asymptomatic cryptococcal antigenemia
Uganda 2019-04-03 2022-04-03 Medical and Health Sciences Non-degree Award
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