Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jackline Kampire
ID:
PHENOTYPIC AND GENETIC CHARACTERIZATION OF LOCAL PIG POPULATIONS IN SOUTH WESTERN AGRO-ECOLOGICAL ZONE (SWAEZ): THEIR DISTRIBUTION AND PORK QUALITY
REFNo: A44ES

1.To map the abundance and distribution of the local pig populations in SWAEZ.
2.To determine the phenotypic features of local pig breeds in SWAEZ.
3.To determine the genetic relationship between local pig populations and exotic breeds in SWAEZ.
4.To determine the pork quality of the local pig populations in SWAEZ.

Uganda 2019-05-28 2022-05-28 Agricultural Sciences Degree Award
joseph  mwizerwa
ID:
Strengthening academic advancement for enrolled nurses: Developing a new program framework for enrolled nurses in Uganda.
REFNo: HS375ES

1.Explore experiences, aspirations and needs of ENs in Uganda with respect to advancing their nursing careers.
2.Identify the barriers and facilitators for academic advancement of ENs within Uganda.
3.Examine the suitability of Ugandan EN advancement programs in meeting EN education needs.
4.Critically examine international educational programs developed for ENs (or similar level nurses) career progression, to assess their applicability to the Ugandan context.
5.Develop a new academic advancement framework for ENs in Uganda and generate consensus for it.

Uganda 2019-05-28 2022-05-28 Medical and Health Sciences Degree Award
Annabel  Morales-Smith
ID:
Assessing local attitudes towards tourism and conservation at Bwindi Impenetrable national park, Uganda
REFNo: SS302ES

This master’s research aims to investigate if park tourism can improve attitudes of residents involved in small-scale tourism enterprises towards protected area conservation, by delivering economic development; using Bwindi Impenetrable National Park (BINP) in Uganda as a case study.
The research objectives are:
• Measure expectations of residents involved in small-scale tourism enterprises based on their experiences of park tourism.
• Evaluating if recent interventions to enhance small-scale tourism enterprises have increased economic benefits from park tourism and if this has improved attitudes towards PA conservation.
• Assess the sustainability of these interventions.
The research hypothesis is: ‘Local attitudes towards protected area conservation improve when residents involved in small-scale tourism enterprises receive benefits from park tourism’.
And the research questions I will ask to test this hypothesis & achieve the aim of this project are:
• What expectations do residents involved in small-scale tourism enterprises have of park tourism?
• Do local attitudes towards protected area conservation improve when residents involved in small-scale tourism enterprises receive benefits from tourism?
• Do people feel they are sufficiently trained to continue without further interventions?

UK 2019-05-21 2022-05-21 Social Science and Humanities Degree Award
Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
IDENTIFICATION OF VIRULENCE FACTORS, TRANSMISSION PATTERNS AND ANTIBIOTIC RESISTANCE MECHANISMS OF EAST AFRICAN Vibrio cholerae ISOLATES BY WHOLE GENOME SEQUENCING
REFNo: HS338ES

Aim: To obtain whole genome sequences (WGS) of Vibrio cholera O1 isolated in various parts of Uganda from 2014 to 2018 and use the data to determine the evolution, spread, antimicrobial resistance mechanisms and pathogenesis of the isolates

Specific objectives:
1. Determine patterns of spread of V.cholerae O1 in Uganda and within the East African region using WGS
2.Infer relatedness and evolution of strains of V.cholerae O1 isolated in Uganda and the East African region from WGS data
3.Identify any uniqueness in virulence genes or their expression among strains of V.cholerae isolated in Uganda and the East African region from WGS data
4.Identify genes of antimicrobial resistance and infer prevailing mechanisms of antimicrobial resistance among V. cholerae O1 isolated in Uganda

Uganda 2019-05-14 2022-05-14 Medical and Health Sciences Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
INVESTIGATION OF THE PHARMACOKINETICS OF ATAZANAVIR IN PREGNANT WOMEN, INDIVIDUALS AT EXTREMES OF BMI, CHILDREN AND ADOLESCENTS. AN OBSERVATIONAL STUDY NESTED WITHIN THE VIRTUAL CONSORTIUM
REFNo: HS351ES

Primary Objectives
1. To describe the pharmacokinetic parameters of ATV currently used in the clinical care of HIV-infected pregnant and postpartum women, children and adolescents, and individuals with obesity or malnutrition.
2. To compare these parameters to those observed in non-pregnant HIV-infected adults on second-line ART who enter a dose escalation study of ATV/r + RIF as WP2 of the VirTUAL programme
Secondary Objectives
1. To use nonlinear mixed-effects modelling to describe sources of variability on the pharmacokinetics of ATV

UK 2019-05-14 2022-05-14 Medical and Health Sciences Non-degree Award
PALLAVI PRABHAKAR
ID:
Reproductive and maternal health care provision for refugees and host populations in Northern Uganda
REFNo: SS296ES

This study aims to undertake: 1.A policy analysis to examine access and health financing arrangements for Sexual , Reproductive and Maternal Healthcare (SRMH) and the delivery of these services for refugees and host populations in Uganda, in the context of transition from an acute emergency to a development response model. 2.An impact , process and economic evaluation of the BRAC ELA programme which aims to train the adolescent girls on issues related to health, nutrition, financial literacy, and life skills.
India 2019-05-14 2022-05-14 Social Science and Humanities Non-degree Award
Daniel  Atwine Warren
ID:
Community Intervention for Tuberculosis Active Contact Tracing and Preventive Therapy - A Cluster Randomized Study (CONTACT)
REFNo: HS329ES

To compare the proportion of household child TB contacts eligible for PT (<5 years and HIV-infected children 5-14 years without active TB) who initiate and complete PT using facility-based and decentralized community-based models of care for contact screening and management.
Uganda 2019-05-07 2022-05-07 Medical and Health Sciences Non-degree Award
Shallon  Atuhaire
ID:
Self-fulfilling Prophecies and Self-efficacy: Association with Community Reintegration and Rehabilitation of Obstetric Fistula Patients in Kitovu Hospital, Uganda
REFNo: HS361ES


i. To identify self-fulfilling prophecies among repaired and unrepaired obstetric fistula patients in Kitovu Mission Hospital.
ii. To assess the highest level of self-efficacy among repaired and unrepaired obstetric fistula patients in Kitovu Mission Hospital.
iii. To determine the role played by self-fulfilling prophecies in community reintegration and rehabilitation of obstetric fistula in Kitovu Mission Hospital.
iv. To measure the association between obstetric fistula patients’ levels of self-efficacy and their rehabilitation in Kitovu Mission Hospital.
v. To explore the extent to which obstetric fistula patients of different fistula repair statuses are involved in rehabilitation in Kitovu Mission Hospital.

Uganda 2019-05-07 2022-05-07 Medical and Health Sciences Degree Award
Musa Kayondo
ID:
PELVIC ORGAN PROLAPSE IN SOUTHWESTERN UGANDA: PATTERNS, IMPACT ON QUALITY OF LIFE, SURGICAL OUTCOMES AND THE PREDICTING FACTORS, OF PATIENTS ATTENDING MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS368ES

1. To determine the patterns of POP in the Gynecology department of MRRH.
2. To establish the quality of life (physical, social, emotional and sexual function) before and after surgery among women with POP at MRRH.
3. To determine the outcomes of surgical treatment and related prognostic factors of POP at MRRH.

Uganda 2019-05-07 2022-05-07 Medical and Health Sciences Degree Award
Katia  Peterson
ID:
A quasi-experimental study of Interpersonal Group Therapy (IPT) treatment attribution on decreasing depression severity among depressed women in Iganga District, Makuutu Sub County and Mukono District, Kimenyedde Sub Counties
REFNo: SS297ES

General objective

To establish a baseline prevalence of depression and determine the period and treatment effects of depression severity between depressed women in Iganga (Makuutu Sub County) and Mukono District (Kimenyedde Sub Counties).

Specific objectives
1. Determine the prevalence of depression in Makuutu Sub County (Iganga) and Kimenyedde Sub Counties (Mukono).
2. Determine the change in depression severity, as measured by the PHQ-9, within control subjects at six months and one year follow up.
3. Determine the change in depression severity, as measured by the PHQ-9, between control and treatment subjects at six months and one-year follow up.
4. Determine the change in well-being as measured by the “Well-being Indicator Survey” within control subjects and between control and treatment subjects at six months and one year follow up.

USA 2019-05-07 2022-05-07 Social Science and Humanities Non-degree Award
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