Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Bruce Kirenga J
ID: UNCST-2019-R001460
Assessment of Nasal Microbiome, Inflammatory Markers, and Infectious Agents among individuals with Biomass Fuel COPD in Uganda ACRONYM: ASCENT–NASAL Study
REFNo: HS6748ES

Aim 1: Characterize the nasal microbiome composition among individuals with and without COPD who
have different levels of air pollution exposure.

Aim 2: Assess nasal inflammatory marker differences among individuals with and without COPD who
are exposed to different levels of air pollution.

Aim 3: Determine the prevalence of viral and bacterial respiratory pathogens among individuals with
and without COPD and their association with PM2.5 exposure.
Uganda 2025-12-01 14:33:20 2028-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Safety, preliminary efficacy, and Pharmacokinetics of Herbal/Natural/ Traditional therapeutic products for the management of Diabetes Mellitus in Uganda.
REFNo: HS6530ES

Main Objective
1. To evaluate the safety, effectiveness and pharmacokinetics of 3 selected NDA- notified herbal/natural/traditional therapeutic products in Uganda, designated IMP1, IMP2, and IMP3.
2. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of natural therapeutics in Uganda.

Specific Objectives
1. To determine the efficacy of selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the treatment of diabetes mellitus in adult patients in Uganda
2. 2. To assess the effect of the selected NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) on specific cardio-metabolic characteristics of adult patients with DM in Uganda.
3. To assess clinical and laboratory adverse events associated with selected NDA- notified herbal/natural/traditional therapeutic products, specifically IMP1, IMP2 and IMP3 in adult patients with DM in Uganda.
4. To investigate the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.
5. To explore the experiences of innovators, researchers, implementers, and participants involved in this study on the innovation and scientific evaluation of herbal/natural/traditional therapeutics in Uganda.e the pharmacokinetic profile(s) of NDA-notified herbal/natural/traditional therapeutic products (IMP1, IMP2 and IMP3) used in the management of DM.

Uganda 2025-12-01 14:19:22 2028-12-01 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Matovu Wasswa
ID: UNCST-2025-R021145
Understanding Power, Institutions, and Policy Dynamics: A Political Economy Analysis of Youth Employment in Uganda
REFNo: SS4607ES

Research Questions The political economy analysis aims to answer two overarching research questions: I. How can current policies and regulatory frameworks be activated and enhanced to provide dignified and fulfilling work opportunities for youth in Uganda? II. What industrial and trade policies and/or plans will enable Uganda to leverage its demographic transition, the 4th industrial revolution, and the evolving digital economy to create adequate opportunities for dignified and fulfilling work for Ugandan youth? Purpose and Objectives The main purpose of this study is to examine how political, institutional, and economic structures interact to shape youth employment outcomes in Uganda. Specifically, the research seeks to: • Map the formal and informal policy, regulatory, and institutional frameworks governing youth employment. • Analyse the interests, incentives, and power dynamics of key actors who influence or obstruct youth employment reforms. • Understand the lived experiences, perceptions, and aspirations of young people in relation to work, inclusion, and voice. • Identify enablers and constraints to the implementation of effective and inclusive employment strategies. • Generate context-sensitive, actionable recommendations for policy and institutional reform.
Uganda 2025-11-26 14:32:03 2028-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Sarah Wilker
ID: UNCST-2025-R019791
One size fits all? Towards individual prediction of treatment success for posttraumatic stress disorder in post-conflict settings (TRAUMA-FIT)
REFNo: HS6712ES

Main Objective 1. to identify individual predictors of treatment response to two different treatments in survivors with PTSD in a post-conflict setting Specific Objectives 1. Investigate whether NET is, on average, more effective than PM+ for the treatment of PTSD 2. Identify predictors of optimal response in the two conditions, and thereby identify predictors of treatment success in a trauma-focused versus present-focused treatment 3. Investigate the explanatory role of socio-ecological factors in PTSD treatment response
Germany 2025-11-26 14:28:24 2028-11-26 Medical and Health Sciences Clinical Trial Degree Award
Pamela Atim
ID: UNCST-2020-R014964
Effects of biomass fuel usage on indoor air quality and associated respiratory health of women and children in Northern Uganda
REFNo: HS6606ES

1.To analyse the trends of biomass fuel usage in Uganda from 2001 to 2022. 2.To determine the factors associated with respiratory symptoms among women and children in rural and urban areas of Northern Uganda. 3.To quantify the levels of personal exposure of women to air particles (PM2.5, PM10) in the different micro-environments. 4.To explore the perspectives of the community and stakeholders regarding the impacts of cooking fuels.
Uganda 2025-11-26 14:26:18 2028-11-26 Medical and Health Sciences Non-Clinical Trial Degree Award
Muzaale tonny
ID: UNCST-2023-R005970
THE CONTRIBUTION OF ALTERNATIVE ASSESSMENT APPROACHES IN ENHANCING THE ASSOCIATION BETWEEN TEACHING AND LEARNING: THE CASE OF SELECTED PUBLIC UNIVERSITIES IN CENTRAL UGANDA. -
REFNo: SS4469ES

i. To establish the relationship between lecture-based instruction and learning in Public Universities in Central Uganda
ii. To establish the relationship between student centered learning and learning in Public Universities in Central Uganda
iii. To establish the relationship between technology based instruction and learning in Public Universities in Central Uganda
iv. To assess the extent to which alternative assessment moderates the association between dynamics of teaching and learning in selected higher institutions of learning
v. To assess the extent to which effective assessment policy implementation moderates the association between teaching and learning in selected higher institutions of learning

Uganda 2025-11-26 14:24:34 2028-11-26 Social Science and Humanities Non-Clinical Trial Degree Award
Denis Gobo
ID: UNCST-2025-R018025
Factors Influencing Adoption of Renewable Energy Interventions: A case of Refugees and Host Communities in Terego District Northern Uganda
REFNo: SS4489ES

1) To determine attitudes towards renewable energy interventions among refugees and the host communities in Terego District. 2) To examine the relevance of renewable energy interventions to refugees and the host communities in Terego District. 3) To determine the effectiveness of renewable energy interventions to refugees and the host communities in Terego District.
Uganda 2025-11-26 14:21:52 2028-11-26 Social Science and Humanities Degree Award
PAUL OPIO
ID: UNCST-2025-R019548
EFFECT OF SPORTS PARTICIPATION ON RETENTION AND ACADEMIC ACHIEVEMENT OF PRIMARY SCHOOL GOING CHILDREN IN KARAMOJA REGION OF UGANDA
REFNo: NS1008ES

To investigate the effect of Sports Participation on retention of Primary School children in Karamoja Region of Uganda.
To examine the effect of Sports Participation on literacy and numeracy of Primary School children in Karamoja Region of Uganda.
To explore the relationship between Sports participation and completion rates of Primary School children in Karamoja Region of Uganda.
To assess the effect of Sports Participation on regular school attendance of Primary School children in Karamoja Region of Uganda.
Uganda 2025-11-26 14:02:49 2028-11-26 Natural Sciences Non-Clinical Trial Degree Award
Julius Tabi Izza
ID: UNCST-2022-R009052
A Theological Reappraisal of Bride Wealth: The Practice of Oku Jeza among Lugbara Christians in the Diocese of Ma'di-West Nile
REFNo: SS4590ES

The study will seek to analyze the challenges of oku jeza, a practice among Lugbara Christian community in the Diocese of Ma’di-West Nile on church marriage and frame theological approach to revisit the practice while maintaining its intended role.
Uganda 2025-11-21 15:07:50 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
Zaina Nabirye Lubwama
ID: UNCST-2025-R022146
The Persistance of Indian Built Heritage in Busoga, Eastern Uganda, 1903-2023.
REFNo: SS4509ES

1. To examine the evolution of Indian-built heritage in Busoga from 1903 to 1962.
2. To analyze how and why Indian-built heritage adapted and maintained its vitality from 1962 to 1979.
3. To examine the changes and continuities of Indian built heritage in Busoga from 1979 to 2023.

Uganda 2025-11-21 14:58:05 2028-11-21 Social Science and Humanities Non-Clinical Trial Degree Award
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