Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Anthony Makhoba
ID:
MODELING A BCG BIRTH DOSE VACCINATION PROGRAM FOR IMPROVED HEPATITIS B CONTROL IN UGANDA
REFNo: HS415ES

1. To determine the rate of BCG birth dose vaccination among newborns at St. Francis Hospital Nsambya and Mbarara Regional Referral Hospital.
2. To determine the time to BCG vaccination among newborns at St. Francis Hospital Nsambya and Mbarara Regional Referral Hospital
3. To establish reasons for missed/delayed BCG vaccination among newborns at St. Francis Hospital Nsambya and Mbarara Regional Referral Hospital and to propose means of improvement.
4. To document the human costs of birth dose vaccination i.e. the nurse time required to obtain maternal consent, to draw up and administer the vaccine and complete the immunization record.

Uganda 2020-03-11 2023-03-11 Medical and Health Sciences Non-degree Award
Sudi Mohamed Ali
ID:
Cervical Cancer: Late presentation and associated factors at Mbarara Regional Referral Hospital.
REFNo: HS485ES

1. To determine the proportion of women with cervical cancer that presents late at Mbarara Regional Referral Hospital. 2. To determine the factors associated with late presentation among women with cervical cancer at Mbarara Regional Referral Hospital. 3. To explore the factors associated with health care seeking from onset of symptoms to diagnosis among women with cervical cancer at Mbarara Regional Referral Hospital.
Kenya 2020-03-11 2023-03-11 Medical and Health Sciences Degree Award
Richard  Muhumuza
ID:
INTEGRATED PREVALENCE MAPPING OF SCHISTOSOMIASIS AND SOIL TRANSMITTED HELMINTHIASIS AMONG COMMUNITIES IN MAYUGE DISTRICT: IMPLICATIONS FOR NTD ELIMINATION PROJECT 2019-2021
REFNo: HS434ES

2. Study objectives
2.1 General objective/Goal
The establish the prevalence of Schistosomiasis and STH infections among school going children and surrounding communities in Mayuge district

Specific objectives
1. To build capacity of Laboratory assistants and technicians on sample (Stool) collection and microscopic analysis
2.To collect sample (Stool) collect from the selected schools
3. To conduct Microscopic analysis for collected samples


Uganda 2020-03-09 2023-03-09 Medical and Health Sciences Non-degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
Assessment of Public Knowledge, Attitudes, and Practices Related to Ebola Virus Disease Prevention and Treatment in Uganda
REFNo: HS531ES

1. Measure district-level estimates in six districts in Uganda of the public’s knowledge, beliefs, attitudes, and practices related to Ebola Virus Disease (EVD) risks due to the ongoing and widespread EVD outbreak in DRC; and
2. Identify socio-behavioral and health system barriers that may hinder the containment of an EVD outbreak in Uganda given the complex socio-political and security context of the protracted outbreak in neighboring DRC.

Nigeria 2020-03-09 2023-03-09 Medical and Health Sciences Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
Improving neonatal outcomes through early detection and management of hypoxaemia: The role of routine pulse oximetry
REFNo: HS132ES

1.To evaluate the effect of routine pulse oximetry on neonatal outcomes in the first 24 hours of life. 2.To determine the utility of pulse oximetry compared to clinical signs in detection of hypoxaemia in neonates with possible serious bacterial infections at lower level facilities 3.To assess the feasibility and acceptability of routine pulse oximetry by healthcare workers and caretakers of newborn babies. 4.To determine the cost-effectiveness of routine pulse oximetry in identifying neonates with hypoxaemia. 5.To describe the maternal factors that predict hypoxaemia in the newborn babies
Uganda 2020-03-06 2023-03-06 Medical and Health Sciences Non-degree Award
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Advancing Tissue and Organ Biobanking in Uganda
REFNo: HS572ES

General objective: To establish a tissue and organ biobank at Makerere University to serve as a catalyst for research in organ collection, biobanking and transplantation in Uganda.
Specific Objective :
1. To train personnel and develop standard operating procedures for collection, processing and storage of human ova, sperm and umbilical cord blood.
2. To collect, process and store human ova, sperms and umbilical cord blood.
3. To develop a publicly accessible catalog of HLA typed viable human tissue and organs.
4. To explore the ethical, legal and societal issues (ELSI) in human tissue and organ biobanking

Uganda 2020-03-03 2023-03-03 Medical and Health Sciences Non-degree Award
ROSE ATIM
ID:
Law, Culture and Reality: Women Navigating Post Conflict Marital Relations in Northern Uganda
REFNo: SS423ES

1. Investigate the legal implication of the institution of marriage on women born in internally displaced peoples camps and victims of sexual violence of the LRA conflict;
2. Interrogate if cohabitation as an alternative to ‘legal’ marriage is becoming institutionalized among women born in internally displaced peoples camps and victims of sexual violence of the LRA Conflict;
3. Analyse the effectiveness of legal and informal marital protection mechanisms in a post conflict society;
4. Interrogate the future of the law in customary marital unions.

Uganda 2020-03-03 2023-03-03 Social Science and Humanities Degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
SAFETY AND EFFICAY OF DOLUTEGRAVIR AND EFV 400 FOR PREGNANT AND BREAST FEEDING WOMEN; A RANDOMISED NON INFERIORITY CLINICAL TRIAL ACRONYM: PREGART
REFNo: HS515ES

PRIMARY OBJECTIVE; to identify safer and more effective ART regimen for pregnant and breast feeding women by comparing three alternative first line ART regimens for their safety and efficacy using randomized clinical trial.

SECONDARY OBJECTIVE; To provide evidence based recommendations for safe and effective first line ART regimens for prevention of mothers to child transmission and treatment of HIV infected pregnant and breast feeding women living in resource limited setting.

Uganda 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
Coleen Sabatini
ID: UNCST-2019-R001321
Outcomes Following Surgical Release of Gluteal Fibrosis in Children of Eastern Uganda
REFNo: HS561ES

This study is a longitudinal case series to evaluate if surgical release of gluteal fibrosis in Ugandan children has a sustained benefit. We will examine the two-year outcomes after surgical release of gluteal fibrosis in children undergoing surgical intervention for gluteal fibrosis.

USA 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
NAASSON TUYIRINGIRE
ID:
Metabolomics Approaches to Elucidate the Mechanisms of Action of Antimycobacterial Medicinal Plants
REFNo: HS422ES

The main objective is to elucidate the mechanisms of action of antimycobacterial medicinal plants using metabolomics. The specific objectives are:
1. To determine the metabolome of M.tb subjected to medicinal plant extracts with antimycobacterial activity as compared to control culture
2. To optimize an analytical metabolomics workflow to facilitate reproducible measurements of bacterial metabolome with extract treatment or without the treatment
3. To elucidate the metabolic pathways affected by plant extracts
4. To identify the macromolecule targets of plant extracts

Rwanda 2020-02-21 2023-02-21 Medical and Health Sciences Degree Award
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