Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Tom  Ngabirano Denis
ID: UNCST-2020-R014491
 Effect of Enhanced Neonatal Jaundice Education on Knowledge, Early Detection and Care Seeking by Postnatal Mothers at Jinja Regional Referral Hospital
REFNo: HS1479ES

Objectives General objective To improve mothers’ knowledge of neonatal jaundice for early detection, proper care and prevention of severe neonatal jaundice. Specific objectives 1. To assess the level of mothers’ knowledge about neonatal jaundice at JRRH. 2. To implement an enhanced neonatal jaundice education package for postnatal mothers at JRRH. 3. To assess the effect of an enhanced neonatal jaundice education package on the level of knowledge, early detection and care seeking by postnatal mothers at JRRH.
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lukia Namaganda Hamid
ID:
Malnutrition as a probable predictor of mortality in cerebral palsy (CP), and the effect of positive deviance and parent facilitator training strategies to malnutrition and caregiving among children and adolescents with CP in the Iganga, Mayuge and Bugweri rural districts of eastern Uganda
REFNo: HS1427ES

Specific Objectives:
1. To assess mortality and whether malnutrition is one of the predictors among a population based sample of children and adolescents with cerebral palsy the Iganga Mayuge-Health and Demographic Surveillance Site (IM-HDSS), Uganda
2. To assess the difference in the change in nutritional status in 2015 and 2019 among children with CP compared to their age and sex matched controls without CP at the IM-HDSS, Uganda.
3. To explore positive and negative nutrition practices among caregivers of well-nourished and under-nourished children with cerebral palsy respectively at the IM-HDSS, Uganda.
4. To determine the difference in the effectiveness of the positive deviance strategy and parent facilitator trainings on CP child and adolescent malnutrition and caregiving within the Iganga, Mayuge and Bugweri districts, Uganda.

 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Clinical Trial Degree Award
Scholastic Ashaba
ID: UNCST-2023-R007613
 Self-management among adolescents living with HIV in Uganda
REFNo: HS1697ES

Aim 3: Assess feasibility, acceptability, and preliminary effects of the self-management intervention on HIV outcomes for ALHIV transitioning to adult HIV care,Aim 2: Develop a self-management intervention that will enable ALHIV to successfully transition to adult HIV care,Aim 1: Use qualitative research to elaborate a conceptual model of the barriers faced by ALHIV transitioning to adult HIV care in Uganda,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Willy Ssengooba
ID: UNCST-2022-R001801
 Evaluation of a new stool-based qPCR for TB diagnosis in children and people living with HIV: a multicentre study in Eswatini, Mozambique and Uganda
REFNo: HS1615ES

To create a biorepository of well characterized pediatric samples at each of the study sites to support the future development and evaluation of novel biomarker research. ,To evaluate the quantitative stool qPCR platform as a tool to monitor treatment response in children and PLHIV,To compare the diagnostic performance of the stool qPCR platform to individual sputum and stool Xpert Ultra, urine LAM, sputum smear, sputum (MGIT) culture results against a clinical diagnosis and bacteriological reference standard,To evaluate the diagnostic accuracy of the stool Mtb qPCR tool compared to a composite reference standard (sputum and stool Xpert Ultra, sputum culture and urine TB-LAM) and clinical diagnosis. ,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lillian Wambuzi Ogwang
ID: UNCST-2021-R013189
 Seroprevalence of SARS-CoV-2 based on antibody testing among HIV infected mothers and their children in the PROMOTE Cohort at the MU-JHU Research Collaboration: July 2020 through June 2021 SUBSTUDY Version 2.0 Dated 16 Jun 2021
REFNo: HS1658ES

1. To determine the seroprevalence of COVID-19 IgG antibody among PROMOTE women living with HIV on antiretroviral therapy, and their HIV exposed children enrolled in PROMOTE; based on Roche ELISA antibody testing of plasma samples collected July 2020 to Jun 2021• To determine the association of COVID-19 exposure and PROMOTE participant characteristics such as age, CD4 count, BMI, maternal ARV therapy, pregnancy, Breast feeding, maternal Viral load, hospitalization in the past year with SARS-CoV-2 antibody positivity, comorbidity diagnosis (e.g. hypertension, obesity, asthma, TB, pulmonary, cardiac, renal disease, sickle cell disease).

3• To use PROMOTE data to determine maternal and pregnancy outcomes among PROMOTE women who were found to have had COVID-19 infection during pregnancy based on antibody testing during the period July 2020 - June 2021.

Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Evaluation of the performance of the Salmonella Biolineâ„¢ typhi IgG/IgM Fast test in a near-patient testing environment, including evaluation of usability
REFNo: HS1700ES

To evaluate the usability of the Biolineâ„¢ Salmonella typhi IgG/IgM Fast test in the near-patient environment using a questionnaire based survey. ,To establish the performance of the Biolineâ„¢ Salmonella typhi IgG/IgM Fast test in a near-patient setting compared to the performance in a professional lab (i.e. Central Public Health Laboratory) using venous whole blood samples. ,
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Clinical Trial Non-degree Award
Martin Ariapa
ID: UNCST-2021-R013296
 Play and Learning in Children’s Eyes
REFNo: SS1022ES

To develop the Children’s Experiences of LtP Protocol (CELP) with its corresponding modules and items, intended for use by a coach or instructional support staff, by soliciting direct insights from children about their LtP experiences. To develop the Formative Observation and Reflection Assessment (FORA) with its corresponding modules and items, intended for use by ECD and primary education teachers as they implement a LtP practice in the classroom. To develop and validate a set of formative tools designed to help teachers in low-and middle-income countries assess and improve their practice in Learning through Play (LtP), through a deeper understanding of how children experience LtP in their classrooms,
 Uganda 2021-09-29 2024-09-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
herbert  Itabangi Itabangi
ID:
Metabolic and Molecular ecological evolution of opportunistic Pulmonary fungal co-infections (MeMoF project)
REFNo: HS1233ES

1. To determine the burden and aetiological profiles of fungal-co-infections among patients with chronic pulmonary disease suspected for Tuberculosis
2. To establish and characterise microbial communities associated with chronic pulmonary disease.
3. To characterise potential interaction relationships established between fungal and bacterial communities.

Uganda 2021-09-27 2024-09-27 Medical and Health Sciences Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
 Utilization of ART and TB treatment during the COVID-19 pandemic: A case of Kampala District
REFNo: HS1471ES

To determine the level of ART and TB treatment utilization among patients during the COVID-19 pandemics in Kampala district
To determine the factors associated with ART and TB treatment utilization among patients during the COVID-19 pandemic in Kampala district
To estimate the incidence rate of loss to follow-up among patients during the COVID-19 pandemics in Kampala district

Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Kiondo
ID:
RISK FACTORS OF GENETIC CONSTITUTION, AND PREDICTORS PERSISTENT DISEASE IN WOMEN WITH MOLAR PREGNANCY ADMITTED AT MULAGO HOSPITAL, KAMPALA, UGANDA: A CASE-CONTROL STUDY
REFNo: HS1442ES

1. To determine the social, medical and obstetric risk factors of HM in women admitted at Mulago hospital, Kampala, Uganda.
2. To outline the outcomes of HM in women admitted in Mulago hospital, Kampala, Uganda.
3. To describe the genetic constitution of HM in women admitted at Mulago hospital, Kampala, Uganda.
4. To determine the predictors of persistent disease in women with HM admitted at Mulago hospital.

 Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FIONA ASIIMWE
ID:
DIAGNOSTIC ACCURACY OF ULTRASOUND AND ADVERSE NEONATAL OUTCOMES AMONG WOMEN WITH A DIAGNOSIS OF NUCHAL CORD DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1531ES

General Objective
To determine the diagnostic accuracy of ultrasound in diagnosing nuchal cord and to compare the proportion of adverse neonatal outcomes between women with and without a diagnosis of nuchal cord among women delivering at Mbarara Regional Referral Hospital.

Specific Objectives
1.To determine the diagnostic accuracy of ultrasound in diagnosing nuchal cord among women delivering at Mbarara Regional Referral Hospital.

2.To compare the proportion of adverse neonatal outcomes between women with and without a diagnosis of nuchal cord delivering at Mbarara Regional Referral Hospital.

Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Lawrence Mugisha
ID:
Evaluation of Wastewater-Based Epidemiology (WBE) tool for surveillance of COVID-19 in selected wastewater treatment plants and channels in Kampala-Entebbe Area, Uganda
REFNo: HS1725ES

Overall Objective: To provide COVID-19 surveillance data for a wider population based on wastewater monitoring as an early warning tool to inform outbreak response strategies
Specific Objective
1. To detect and characterize the SARS-CoV-2 virus in wastewater from wastewater treatment plants, channels and septic tanks of hospitals in Kampala and Entebbe
2. To evaluate and standardise the molecular detection methods for WBE


 Uganda 2021-09-24 2024-09-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 COMPARISON OF PERFORMANCE OF CAPILLARY BLOOD VS VENOUS BLOOD ON SYPHILIS ULTRA TEST DEVICE/ TEST REF: ISY-U402 AND CAPILLARY BLOOD VS VENOUS BLOOD ON SYPHILIS ULTRA RAPID TEST STRIP) REF: ISY-U401 USING SD BIOLINE VERSION 3.0 AS A REFERENCE
REFNo: HS1643ES

The objective of this evaluation is to demonstrate the equivalence of capillary (fingerprick) whole blood and venous whole blood on the Syphilis Ultra test device/ Test strip (Whole Blood/Serum/ Plasma) and strip.
2.4 Exploratory Objectives
• To determine the diagnostic accuracy of the Syphilis Ultra test device/ Test (Whole Blood/Serum/ Plasma) and strip.

 Uganda 2021-09-23 2024-09-23 Medical and Health Sciences Clinical Trial Non-degree Award
Christopher Dolan Gerald
ID:
Improving access and retention in inclusive education for refugee children with disabilities
REFNo: SS937ES

I.To explore stakeholder’s understanding of the processes, challenges and opportunities for refugee children in accessing and progressing in inclusive education
II.To establish the current capacity of the education system to deliver safe and inclusive quality education for refugee children with special needs and disabilities
III.To describe the extent to which RCSN and their caretakers access timely and appropriate support to improve their physical, psychological and social functionality
IV.To establish the extent to which Key stakeholders effectively champion social accountability and implementation of policies and commitments on inclusive education
V.To examine the daily needs of RCWD and their carers

UK 2021-09-23 2024-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robens Mutatina
ID: UNCST-2021-R013633
 Psychosocial challenges and Coping Strategies among Caregivers of Children with Cerebral Palsy in South Western Uganda
REFNo: SS762ES

To determine the psychosocial challenges faced by caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

To describe the coping strategies of caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

 Uganda 2021-09-22 2024-09-22 Social Science and Humanities Non-degree Award
Samuel Biraro
ID:
Assessing the impact of COVID-19 on routine immunization demand and uptake, and understanding COVID-19 attitudes and perceptions in Uganda
REFNo: HS1679ES

1. Identify the range of factors affecting routine immunization uptake during the COVID-19 pandemic in order to inform key areas for mitigation intervention; and
2. Generate timely data on the range of factors that may influence demand and uptake of the COVID-19 vaccines among HCW and the public to identify strategies to promote optimal uptake of the COVID-19 vaccines.


Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary  Nanteza Bridget
ID:
ASSESSING A UGANDAN COMMUNITY FOR ACCEPTABILITY, SHORT- AND LONG-TERM SIDE EFFECTS OF COVID-19 VACCINE UPTAKE AND THE COLLECTION OF RELEVANT BIOLOGICAL SPECIMENS TO SUPPORT IMMUNOLOGICAL, HOST, AND VIROLOGICAL STUDIES ON COVID-19 VACCINE.
REFNo: HS1660ES

STUDY GOAL AND OBJECTIVES
The overall objective of this study is to assess acceptability, document short and long-term side effects, characterize break-through viruses that are linked to COVID-19 vaccination, and collect specimens for studies aimed at understanding host, viral and immunological factors associated with COVID-19 vaccine.
Specific objectives:
1. To assess the community knowledge, attitudes and perceptions (KAP) towards COVID-19 vaccines.
2. To describe the short and long-term side effects of COVID-19 vaccine provided at the UVRI clinic
Blood specimens will be collected for the following immunological and virological studies below:
3. To describe the sensitivity of COV ID-19 breakthrough viruses to prior and co-existing anti-SARS-COV-2 antibody and cellular immune responses after immunization with or without prior history of COVID-19 infection; and to also isolate SARS-CoV-2 Spike-specific human monoclonal antibodies in volunteers with strong neutralization responses.
4. To describe the correlation between pre-COVID-19 vaccination immune status, and outcome of vaccine induced immunity in newly vaccinated persons.
5. To describe COVID 19 immune responses in unvaccinated and already vaccinated persons before and after incident infections
6. To describe break-through viruses following COVID-19 immunization among the vaccinated persons

7. To describe host genetic factors that could be relevant for immune protection and disease outcome

Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Transitioning children to Optimal Regimens of Paediatric Dolutegravir (TORPEDO) in Uganda
REFNo: HS1596ES

the primary objective for the study is to assess patients’/ caregivers’ preference for a paediatric DTG regimen over their previous regimen, when transitioned from another regimen.

 Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Clinical Trial Non-degree Award
Jihane Farhat Ben
ID:
Evaluation of two strategies part of the Differentiated Services Delivery Models (DSDM) in Fishermen’s landing sites at Lakes George and Edward, Western Uganda.
REFNo: HS1574ES

The main objective of the study is to describe acceptability and outcomes (VL suppression and
retention) relevance of MSF Landing site activities for the target populations to reorient
activities and document best practices.
The specific objectives are:
- To measure the proportion of eligible patients who enrol in CCLADs and FTR
- To compare characteristics of patients choosing CCLAD with those choosing FTR
- To measure the retention in care in CCLADS and in FTR at 6 and 12 months
- To measure the viral suppression for patients enrolled in CCLADS and in FTR for at least 1 year
- To describe acceptability and relevance of DSDM, peer zonal leaders, peers at the health facilities, VIP clinic days, OJT/CMEs for health workers and the information points.

France 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
IVAN IBANDA
ID:
Diagnostic and Treatment Delay of Tuberculosis: An In-depth Analysis of the Health-Seeking Behavior of Patients and the Health System Response in Kampala District
REFNo: HS1654ES

To determine the patient and system related factors that contribute to both diagnosis and treatment delays in Kampala District,To determine the proportion of patients that have a treatment delay for tuberculosis in Kampala District.,To determine the proportion of patients with tuberculosis diagnostic delay in Kampala District.,To evaluate the extent of diagnostic and treatment initiation delays of TB patients, identify the major contributors to such delays (patient or system), and study their various determinants.,
 Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Goylette Chami
ID: UNCST-2023-R006262
 SchistoTrack: Determinants of schistosomiasis infection and morbidity as part of the Oxford-Uganda Collaboration on Schistosomiasis
REFNo: HS1664ES

Determine whether infection indicators are informative for measuring morbidity risks
associated with schistosomiasis;
2. Prioritize the most common morbidities associated with schistosomiasis, by age, that
require treatment and further research;
3. Understand the relative importance of environmental factors versus current infections for
schistosomiasis- associated morbidities.
4. Assess the feasibility of large-scale tracking of individuals with wearable GPS;
5. Determine whether spatial indicators from wearable devices can better predict individual
infection risk when compared to conventional approaches such as household surveys;
and
6. Develop methods to classify water contact sites based on individual usage and
contamination to understand whether there are focal points for transmission or super
spreaders.
USA 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
 Development and implementation of a patient-centred peer support intervention to promote the detection, reporting and management of adverse drug reactions among people living with HIV in Uganda
REFNo: HS1206ES

To estimate the effectiveness of the peer support intervention on the rate of ADR-reporting by PLHIV receiving DTG and/or IPT in Uganda,To describe the patterns of ADR-reporting (number, rate, time to reporting, seriousness) by PLHIV receiving DTG and/or IPT in whom the peer support intervention is implemented in Uganda,To determine the barriers and facilitators to implementation of the peer support intervention to promote ADR detection, reporting and management among PLHIV on DTG and/or IPT in Uganda,To develop an innovative peer support intervention for promoting the detection, reporting and management of ADRs in PLHIV receiving DTG and/or IPT in Uganda,
 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
 Community Engagement and Schistosomiasis Prevention: A Sociological Analysis of the Citizen Science Model among Selected Communities of Western Uganda
REFNo: SS836ES

Purpose of the study
The purpose of the study is to examine the effectiveness of the Citizen Science model in community engagement to the prevention of schistosomiasis among selected communities of western Uganda. To do this, the study will determine the socio-cultural barriers to the uptake of preventive measures to guide in the development of health education initiatives that can be executed by the Citizen Scientists to help change the behaviour of the community for the prevention of schistosomiasis.

Objectives of the study
This shall be guided by the following research objectives:
1. To determine the level of knowledge, attitude, and practice regarding schistosomiasis among communities of Western Uganda;
2. To explore the health-seeking practices, attitudes, and behaviour associated with schistosomiasis prevention among communities of Western Uganda
3. To understand the lived experiences and perceptions of schistosomiasis by communities of Western Uganda to determine how citizen scientists can be useful in shaping community perspectives
4. To develop and implement contextualized communication strategies for schistosomiasis prevention based on the outcome of the objectives above with help of the citizen scientists
5. To assess the role of the citizen science model of community engagement in the prevention of schistosomiasis among communities of western Uganda

 Uganda 2021-09-21 2024-09-21 Social Science and Humanities Non-Clinical Trial Degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Rheumatic Heart Disease Community Streptococcal Treatment Program “RESET”
REFNo: HS1580ES

To improve the algorithm of the Strepic® device for Group A Strep Pharyngitis detection and then to test the performance as compared to microbiological culture (gold standard) and clinical decision rule.,To increase health seeking behavior for sore throat through a multifaceted community awareness campaign.,To improve guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based primary prevention.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ELIZABETH NALINTYA
ID: UNCST-2021-R012882
 Long title: A community-based Phase III, cluster randomized trial of point-of-care CD4 testing and enhanced screening and prophylaxis in advanced HIV disease Short title: An enhanced package of care to reduce mortality in advanced HIV disease
REFNo: HS1605ES

Primary Objectives:
1. To assess 24-week survival with retention in care in persons with advanced HIV disease (CD4<200 cells/µL) with point-of-care CD4 testing compared to standard flow cytometry
2. To assess 24-week survival with retention in care with an enhanced diagnostic OI screening and prophylaxis strategy compared to standard WHO package of care in persons with advanced HIV disease
Secondary Objectives:
1. To determine incidence of OIs
2. To measure adverse events with enhanced prophylaxis regimens
3. To assess tolerability and adherence of enhanced prophylaxis regimens
4. To determine incidence and cause of hospitalization for persons with advanced HIV disease
5. To determine cause of death for persons with advanced HIV disease
6. To determine HIV outcomes of viral suppression in persons with advanced HIV disease.
7. Measure cost, cost-effectiveness, and budgetary impact of the CD4 testing strategies, and OI screening and prophylaxis strategies.

 Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Clinical Trial Non-degree Award
Graham Birch John
ID:
Title of research project: Oxidative shielding and the inter-generational costs of reproduction in male wild banded mongooses
REFNo: NS164ES

(1) To understand transgenerational influences on health and reproductive success in
wild mammals.
(2) To investigate the impact of paternal health on the development and reproductive
success of offspring, using banded mongooses as a model system.
 UK 2021-09-20 2024-09-20 Natural Sciences Degree Award
Fabian Mwosi
ID:
RETIREMENT PLANNING AND SOCIO-ECONOMIC STATUS OF CIVIL SERVANTS IN BUSOGA SUB-REGION, UGANDA.
REFNo: SS843ES

i. Investigate the relationship between saving culture and socio-economic status of retired civil servants in Busoga sub-region, Uganda
ii. Examine the relationship between financial planning and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iii. Assess the relationship between lifestyle and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iv. Explore the moderating effect of demographic factors on the relationship between retirement planning and socio-economic status in Busoga sub-region, Uganda
 Uganda 2021-09-20 2024-09-20 Social Science and Humanities Non-Clinical Trial Degree Award
Asenath Kwagalakwe
ID:
Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS252ES

Investigating the physics of strain accommodation in the magma-poor Albertine-Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Hillary Mwongyera
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS264ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
 Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Determining the Effectiveness of Dispensing Messages (DEDIM) on Adherence and Viral Suppression among Children with an Unsuppressed Viral Load in Uganda
REFNo: HS1544ES

General Objective
To determine the effectiveness and implementation of dispensing messages on adherence and viral suppression among children with an unsuppressed viral load in Uganda

Specific objectives
1. To determine the facilitators and barriers to the delivery of dispensing messages to caregivers of children (< 15 years) living with HIV with an unsuppressed viral load in Uganda to inform the implementation strategy.
2. To assess the effectiveness of dispensing messages on outcomes of adherence and viral load suppression among children (<15 years) living with HIV with non-suppressed viral loads in Uganda.
3. To identify processes and contextual factors that explain the uptake, reach, and fidelity of delivery of ART dispensing messages to caregivers of children (< 15 years) living with HIV with unsuppressed viral load in Uganda

 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 The development and evaluation of a mobile phone-based intervention to facilitate continuity of care, symptom monitoring and self-management in palliative care patients in Uganda
REFNo: HS1600ES

vi. To develop best practices for patient-public engagement to empower cancer patients to support research in palliative care at different stages,v. To identify mechanisms of action for the intervention in supporting palliative care patients and their families ,iv. To determine uptake, patterns of clinical palliative care practice and factors influencing engagement with the mobile application ,iii. To deliver the novel intervention to two cohorts of palliative care patients , ii. To determine optimal implementation within routine palliative care practice at Yumbe Regional referral hospital palliative care unit and New Life Hospice ,i. To develop and evaluate a mobile phone-based (mpalliative) intervention to collect outcomes data and COVID-19, TB and hepatitis B symptoms from palliative care patients alongside developing a web-based application to communicate data to palliative care teams and facilitate continuity of care and self-management in palliative care patients in Uganda ,
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Uganda TB Care Cascade
REFNo: HS1718ES

1. To evaluate the accuracy of DHIS2 TB surveillance data using quantitative and mixed-methods approaches. 1a. To compare the accuracy of TB quality indicators measured with aggregate data compared to those measured with individual-level data. 1b. To explore discrepancies in the DHIS2 data using qualitative interviews.
2. To use routine surveillance data to describe the quality of TB care in Uganda.
3. To measure the impact of Xpert MTB/RIF on TB indicators in Uganda.
 Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 THRiVE Research Enrichment: Community and Public Engagement for Enhanced Impact
REFNo: HS1586ES

1. To enable doctoral trainees to work with young people in schools who will identify their preferred ways for engagement with THRiVE research.
2. To co-create and co-design at least one engagement project at each school led by student champions in collaboration with doctoral trainees and implemented based on one or more ways identified in objective 1 above.
3. To co-design and implement at least one student-centred drama skit and/or games for engagement of students with THRiVE doctoral trainees’ research, utilizing findings from objective one.
4. To publicize the public engagement in research work to stakeholders as a way of stimulating engagement of young people and doctoral trainees in PER.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane  Namusisi
ID: UNCST-2021-R013619
 seizure control and associated factors among children with epilepsy at Mbarara Regional Referral Hospital
REFNo: HS1657ES

MAIN OBJECTIVE
To determine the seizure control status and describe its associated factors among children attending the Epilepsy Clinic at MRRH for at least six months.
SPECIFIC OBJECTIVES;
1. To identify the seizure types among children under care for at least six months at the Epilepsy Clinic, MRRH.
2.To determine the proportion of children with epilepsy with poor seizure control under care for at least six months at the MRRH Epilepsy clinic.
3.To identify the factors associated with poor seizure control among children under care for at least six months at the MRRH Epilepsy clinic.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Human-Centred Design and Communities of Practice to Improve Delivery of Home based Tuberculosis Contact Investigation in Uganda
REFNo: HS1720ES

General Objective: The study aims to assess the effectiveness of an enhanced intervention strategy for implementing TB contact investigation relative to usual care. Specific Objectives: 1.To compare the implementation, effectiveness, and public health impact of TB contact investigation delivered via an enhanced intervention strategy vs. the usual care strategy in a stepped-wedge, cluster-randomized implementation trial. 2.To identify implementation processes and contextual factors that influence the effectiveness of the intervention strategy for TB contact investigation. 3.To compare the costs and epidemiological impact of the intervention and usual care strategies for TB contact investigation.
Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 SeqCOVID consortium: EAC participation – Sequencing of COVID-19 isolates from the East African Region
REFNo: HS1592ES

Epidemiological Analysis of current COVID outbreak,Capacity Building in East Africa and setting up of Prospective COVID Surveillance Platform,Diagnostic and Vaccine Development for East African COVID variants: - describe East African COVID variants and predict immunogenic epitopes and drug targets in silico, The aim of the present project is for the East African region to actively contribute data for COVID-19 drug and vaccine development, to equip the region for the time after a vaccine and drugs were developed and also to prepare for future outbreaks.,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Nalumu
ID:
ASSESSING FACTORS ASSOCIATED WITH NEONATAL DEATHS IN BUSIA DISTRICT; CASE STUDY OF MASAFU, DABANI AND BUSIA HEALTH FACILITIES
REFNo: HS1711ES

1. To assess factors associated with neonatal deaths in Busia district such that we make recommendations, according to the findings, on what measures to adopted in order to reduce neonatal mortality in the district and the country,4. To examine health facility factors associated with neonatal deaths in Busia district,3. To establish neonatal related factors associated neonatal deaths in Busia district ,2. To determine maternal factors associated with neonatal deaths in Busia district ,
 Uganda 2021-09-16 2024-09-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Janet SEELEY
ID:
Multimorbidity in Africa - Increasing Understanding of the Health Workers’ Experiences and Epidemiology (MAfricaEE)
REFNo: SS998ES

Explore the healthcare professionals' (HCPs) experiences of treating and managing patients with multi-morbidity in Uganda and what health workers see as the main barriers to optimal care provision. How do health care professiönals view the potential impacts of COVID-19 on care for patients with multi-morbidity?
 UK 2021-09-13 2024-09-13 Social Science and Humanities Non-Clinical Trial Non-degree Award
Frederick  Oporia
ID:
Improving use of seaworthy life jackets among boaters on Lake Albert, Uganda. A cluster randomized trial
REFNo: SS992ES

1. To estimate the prevalence of life jacket use among boaters on Lake Albert.

2. To identify the determinants of life jacket use among boaters on Lake Albert

3. To determine the seaworthiness of life jackets used by boaters on Lake Albert

4. To design a behavior change intervention aimed at improving use of seaworthy life jackets among boaters on Lake Albert

5. To pilot and evaluate the effectiveness of a behavior change intervention on improving use of seaworthy life jackets among boaters on Lake Albert

 Uganda 2021-09-10 2024-09-10 Social Science and Humanities Degree Award
Carolyn Pelnik
ID:
Identifying and Easing Constraints on Microenterprise Location within Kampala, Uganda
REFNo: SS935ES

This project asks whether business relocation within the city could increase profits for microfirms in Kampala, Uganda, and if so, then what frictions (constraints) restrict a firm’s ability to relocate without intervention. Ultimately, this project plans to use a multi-arm randomized experiment to accomplish 3 aims: to detect appetite for business relocation, whether relocation increases profits, and which of the tested frictions might constrain location choice. In the first phase of the research, the project will survey microfirms in Kampala to understand their current locations, how profits vary by location across the city, what aspirations the business owners have with respect to future business growth, and what challenges they perceive to accomplishing business growth.
USA 2021-09-10 2024-09-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paineto Masengere
ID: UNCST-2021-R013195
 Perceptions, barriers, and facilitators of adoption of healthy lifestyles for cardiovascular disease prevention among slum communities in Kampala, Uganda
REFNo: HS1661ES

1. To explore how slum dwellers in Kampala district define a healthy lifestyle in the context of cardiovascular disease prevention.
2. To explore the barriers and facilitators to adopting recommended lifestyles for cardiovascular disease prevention among slum dwellers.
3. To explore the potential roles of community actors in slums in cardiovascular disease prevention.

Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Felix Oyania
ID: UNCST-2021-R013492
 Feasibility of Primary Repair for Anorectal Malformations in Uganda
REFNo: HS1632ES

To determine the feasibility of primary repair for anorectal malformations in Uganda.,
 Uganda 2021-09-10 2024-09-10 Medical and Health Sciences Non-Clinical Trial Degree Award
FRANK MULINDWA
ID:
Changes in insulin kinetics after withholding dolutegravir in Ugandan HIV patients who develop diabetes while on dolutegravir.
REFNo: HS1493ES

To determine changes in; insulin secretion, insulin sensitivity, insulin clearance and HBA1C at 24 weeks after DTG discontinuation in Ugandan HIV patients who develop diabetes while on DTG.
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Martha Musyoka Mbenia
ID:
PREDICTORS OF ADVERSE FETO-MATERNAL OUTCOMES AMONG MOTHERS ADMITTED WITH ANTEPARTUM HEMORRHAGE AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1450ES

To describe adverse outcomes and determine predictors of adverse feto-maternal outcomes in mothers with antepartum hemorrhage at Mbarara Regional Referral Hospital
 Kenya 2021-09-09 2024-09-09 Medical and Health Sciences Clinical Trial Degree Award
Jimmyy Opee
ID:
PROPORTION AND FACTORS ASSOCIATED WITH INTRA-PROCEDURAL PAIN AMONG WOMEN UNDERGOING MANUAL VACUUM ASPIRATION FOR INCOMPLETE ABORTION AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1462ES

General objective
To determine the proportion and factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

Specific objectives
1. To determine the proportion of women with intra-procedural pain undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.
2. To determine the factors associated with intra-procedural pain among women undergoing Manual Vacuum Aspiration for incomplete abortion at gynecology ward at Mbarara Regional Referral Hospital.

 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Ronald Mulebeke
ID:
A pilot study to assess the impact of Supportive Supervision and Behavior Change Communication at private health facilities in Uganda
REFNo: HS1588ES

This study will assess the impact of supportive supervision and behaviour change communication to improve the quality of malaria care and data management delivered by clinicians at private health facilities in Uganda.
Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANTHONY KAYIIRA
ID: UNCST-2020-R014108
 Understanding Reproductive Health among Survivors of Paediatric and Young adults (URHSPY) Cancers: a mixed method study
REFNo: HS1652ES

To explore the knowledge, perceptions, and attitude of; parents or caretakers of children with cancer, and health workers on cancer treatment-related reproductive morbidity, at the Uganda Cancer Institute,To describe self-reported reproductive morbidity associated with cancer treatment among childhood and young-adult cancer survivors.,To establish the extent of reproductive morbidity associated with cancer treatment among young cancer survivors in Uganda. In addition, we aim to explore the contextual enablers and barriers to addressing cancer treatment-related reproductive morbidity in Uganda.,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Study Protocol for the Evaluation of Covid 19 Antibody and Antigen Rapid Diagnostic Test (RDT) In the EAC Partner States
REFNo: HS1591ES

Evaluation of ELISA cross-reactivity on stored archived negative samples between East African Partner States. ,Evaluation RDT performance differences between the East African Partner States,- Evaluate the clinical specificity of antibody RDT and ELISA using serum/plasma specimens from COVID-19 negative specimens from pre-COVID-19 (archived stored samples),- Evaluation of COVID19 antibody RDTs and ELISA’s in the East African region, using serum/plasma samples from COVID-19 confirmed based on RT-PCR results (RT-PCR positive test results). ,Evaluation of COVID19 antigen RDTs against gold standard PCR in the East African region,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 Evaluation of TUBEX Typhoid TF IgM Antibody test for Early Diagnosis of Typhoid fever Among patients in Uganda
REFNo: HS1548ES

1) To carry out blood culture testing on all samples from patients with signs and symptoms of typhoid fever in the selected facilities of Uganda.
2) To carry out serological testing for Salmonella antibodies using the TUBEX Typhoid TF IgM Antibody test on the serum samples of consented/assented patients whose samples grew Salmonella Typhi.

 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Exploring the impact of out-migration on remaining partners’ HIV and sexual behavior perceptions and practices in Rakai, Uganda: a qualitative study.
REFNo: SS981ES

The overall aim of this study is to qualitatively explore the impact of out-migration amongst heterosexual couples on non-migrating partners’ HIV and sexual behavior perceptions and practices in Rakai, Uganda.
Uganda 2021-09-09 2024-09-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 TRUST IN MEDICAL RESEARCH AMONG PATIENTS AT A REGIONAL REFERRAL HOSPITAL AND COMMUNITY MEMBERS IN LIRA DISTRICT, NORTHERN UGANDA
REFNo: HS1685ES

Explore community perceptions of trust in medical research,2. Determine the other factors associated with trust of medical research,1. Compare level of trust for medical research among community members and persons that are hospitalized.,To compare the level of trust in medical research among people hospitalized at a hospital and the community members, identify associated factors and explore prevailing community perceptions of trust in medical research.,
 Uganda 2021-09-09 2024-09-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Daniel Mongovin David Thomas
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS160ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
 USA 2021-09-08 2024-09-08 Natural Sciences Non-Clinical Trial Degree Award
Julian Bagyendera Kobutungi
ID:
Gender, Youth and Social Inclusion Baseline Assessment for the USAID Local Partner Health Services – Ankole (USAID LPS – Ankole)
REFNo: SS1002ES

The main objective is to conduct a mixed method gender and youth social inclusion assessment which includes a literature review; collection of primary quantitative and qualitative data.,
 Uganda 2021-09-08 2024-09-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 UNDERSTANDING PATHOGENESIS OF BURKITT LYMPHOMA TO DEVELOP BETTER TREATMENTS FOR AFRICAN ENDEMIC BURKITT LYMPHOMA
REFNo: HS1546ES

4. To establish a BL tumor biorepository at the Uganda Cancer Institute ,3. To generate PDX mouse models of BL to understand the molecular factors that govern response to COM therapy in children with endemic BL at the Uganda Cancer Institute. ,2. To describe the molecular differences between endemic BL and sporadic BL. ,1. To determine the molecular profile of endemic BL tumors at the Uganda Cancer Institute,
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 PERFORMANCE EVALUATION OF COVID-19 ANTIGEN RAPID DIAGNOSTIC TESTS
REFNo: HS1690ES

To determine the association of positive index test results with disease stage (days since symptom onset, e.g. acute, early, late), symptom severity and symptom severity.,To determine the diagnostic accuracy of SARS-CoV-2 Ag RDTs on a respiratory specimen (NP swab, OP swab, nasal swab, saliva), vs Cobas SARS-CoV-2 assay as performed in patients presenting with influenza-like illness.,
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A clinical trial to assess the safety and immunogenicity of LNP-nCOV saRNA-02, a self-amplifying ribonucleic acid (saRNA) vaccine encoding the S glycoprotein of SARS-CoV-2, the causative agent of COVID-19, in SARS-CoV-2 seronegative and seropositive Uganda population
REFNo: HS1641ES

Primary Objective:

• To compare the safety and immune responses for SARS-CoV-2 seronegative and seropositive individuals from two immunisations with LNP-nCOV saRNA-02 administered IM 4 weeks apart at one dose level in 42 participants age 18-45 years.

Exploratory Objectives:
• To characterise the humoral and cellular immune responses to LNP-nCOV saRNA-02 administered at one dose given at 0 weeks and 4 weeks for individuals seronegative and seropositive for SARS-CoV-2 antibodies
• To characterise the profile of class and sub-class of antibody responses
• To characterize infection induced immune responses in participants with naturally acquired infection who are also exposed to the vaccine

 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Clinical Trial Non-degree Award
David Musoke
ID:
Collaboration between Biomedical and Traditional Mental Health Service Providers in Wakiso District, Uganda
REFNo: HS1581ES

To explore how biomedical service providers and traditional healers can work together to improve access to mental health care in Wakiso district, Uganda.
 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janet SEELEY
ID:
Examining ethical issues, stakeholder engagement and acceptability of biobanking in Sub-Sahara Africa
REFNo: HS1645ES

General Objectives:
To explore perceptions, informed opinion and experiences of key stakeholders on approaches and value of community engagement in biobanking in LMIC; and if and how community approval should be obtained.

Specific Objectives:
1. To explore key stakeholders’ perceptions, informed opinions and underlying values around potential benefits of biobanks in SSA and important aspects of operationalising a biobank in LMICs.
2. To describe approaches that could be used to engage communities and stakeholders about biobanking.
3. To examine governance systems and structures that should be in place for a biobank to become operational, and ways in which community voices might be included in those systems
4. To determine initial key elements required to assume a community social license based on outputs of 1-3

UK 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edward  Mukiibi
ID:
RESEARCH DATA MANAGEMENT PRACTICES IN SELECTED HEALTH INSTITUTES IN UGANDA
REFNo: HS1714ES

i) To describe the characteristics of research data created and held in selected Health Institutes in Uganda.

ii) To examine the research data management practices in selected Health Institutes in Uganda.

iii) To evaluate research data management readiness of selected Health Institutes in Uganda.

iv) To explain the challenges affecting adoption and uptake of RDM practices in selected Health Institutes in Uganda.

v) To propose interventions to improve RDM practices in selected Health Institutes in Uganda.

 Uganda 2021-09-08 2024-09-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Zarin Machanda Machanda
ID:
The form and functions of leadership in wild chimpanzees
REFNo: NS288ES

This project will establish chimpanzees (Pan troglodytes) as a new comparative model of human-like leadership by testing how individual variation across a leader’s temperament, behaviour, and physiology shapes collective action in natural social groups. The first aim of the project is to support continuing long-term data collection by the Kibale Chimpanzee Project. We have three additional research aims that are specific to this project: (1) to identify and describe different domains of leadership in wild chimpanzees; (2) identify and describe the characteristics of chimpanzee leaders; and (3) evaluate the success of different pathways to leadership for chimpanzees. This project aims to collect both observational and experimental data that will provide detailed empirical insight into leadership among wild chimpanzees
 USA 2021-09-08 2024-09-08 Natural Sciences Non-Clinical Trial Non-degree Award
Robert Opika Opoka
ID: UNCST-2021-R014036
 An implementation toolkit for the use of hydroxyurea in the treatment of sickle cell anemia in Ugandan children
REFNo: HS1646ES

1) Assess the uptake and proper use of hydroxyurea among SCA patients at Jinja and Atutur Hospitals as a result of the implementation toolkit pilot,
 Uganda 2021-09-03 2024-09-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Walter Ojok
ID: UNCST-2021-R004415
 SYNTHESIS OF NOVEL MESOPOROUS ADSORBENTS FOR FLUORIDE REMOVAL FROM WATER
REFNo: NS158ES

(i) To study the hydrochemical characteristics of Ndali-Kasenda crater lakes used as water sources with focus on the occurrence and spatial distribution of fluoride.
(ii) To explore the possibility of synthesizing biosorbents for fluoride removal using local base materials (Phoenix reclinata seeds, cassava starch and banana extract as soft templates.
(iii) To conduct batch and column experiments on removal of fluoride using synthesized biosorbents to assess their fluoride removal performance.
(iv) To design laboratory scale pilot column filter studies for fluoride removal with high performance synthesized biosorbent for Ndali-Kasenda lake water.

Uganda 2021-09-03 2024-09-03 Natural Sciences Degree Award
Suzan van der Lee
ID:
Dry Rifting In the Albertine- Rhino Graben, Uganda (DRIAR)
REFNo: NS255ES

A geophysical, geochemical, geological, and geodynamic investigation of the Albertine-Rhino Graben in western and northwestern Uganda to improve our understanding of continental rifting in areas where volcanic activity is minimal.
Netherlands 2021-09-03 2024-09-03 Natural Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 FOOD CHOICES AND THE FOOD ENVIRONMENT OF SMALL-HOLDER FARMERS IN MPIGI
REFNo: A146ES

Examine factors influencing maternal food choices and nutrition outcomes and understand how they interact.,Explore the internal and external food environments and how they impact food choice among rural female smallholder farmers,Determine the relationship between agricultural activities on maternal time use and food choices among rural female smallholder farmers,Determine the daily time use patterns of rural female smallholder farmers,Assess the nutritional status of rural female smallholder farmers,To examine the dynamic interactions between women’s time use and food environments and their influence on food choices and nutrition outcomes of rural smallholder female farmers living in Mpigi district,
 Uganda 2021-09-03 2024-09-03 Agricultural Sciences Non-Clinical Trial Non-degree Award
Tu Hoang Phuong
ID:
Forest succession analyses in Kitigo as a basis for close-to-nature reforestation planning
REFNo: NS279ES

To understand the details of termite-fungi relationships in the context of soil nitrogen allocation in Central African derived savanna; to clarify and classify the Nitrogen absorption strategies of various woody species/tree families, in order to develop crucial criteria for tree species selection for Nitrogen limited target sites; to work out if Nitrogen-15 of tree’s living sapwood could be an indicator for soil nitrogen availability.

 Vietnam 2021-09-03 2024-09-03 Natural Sciences Non-Clinical Trial Degree Award
Cristina Clerici
ID:
Yes, women can. The role of information and norms in encouraging women to enter male-dominated sectors in Uganda
REFNo: SS968ES

Gain insights on information available to aspiring female entrepreneurs and the constraints they face when choosing their sector of business.
 Italy 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Ziidah Namwaya
ID:
Exploring the use of Active Birthing Techniques for Normal Labour and Birth among Midwives working in the Metropolitan Region, Kampala-Uganda
REFNo: SS976ES

1. To evaluate the status of the environment in the three health facilities Kitebi, Komamboga and Kisugu as regards the use of active birthing techniques
2. To identify the available active birthing techniques at the health facilities
3. To assess current practice as regards the use of active birthing techniques for normal labour and birth among midwives working at the health facilities
4. To determine the level of knowledge as regards the use of active birthing techniques
5. To explore the potential factors that might influence the use of active birthing techniques for normal labour and birth among midwives working at the facilities
6. To describe the acceptability and experience of using upright positions such as hands- and-knees position, squatting, leaning forward, kneeling among pregnant women and midwives in the selected health facilities.

 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
 Assessment of indoor air quality, risk factors and potential health effects among residents in an urban informal settlement in Kampala, Uganda
REFNo: SS996ES

To describe the potential health effects associated with indoor air pollution. ,To assess the factors associated with indoor air pollution among households. ,To determine the levels of indoor PM2.5, and Carbon monoxide (CO) in households., To determine levels of indoor air pollution, its associated risk factors and potential health effects among residents in an informal settlement in Kampala so as to generate information that can be used in design appropriate strategies, policies and practices that promote good air quality in households, hence mitigate health problems associated with indoor air pollution. ,
 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Amy  Ritterbusch Elizabeth
ID:
Child Protection Mapping and Honour
REFNo: SS970ES

1.To examine the effect of global narratives of child wellbeing on child protection and rights practices in Uganda
2.To explore prospects for local child protection practices in informing and enriching global child protection policy
3.To explore the concept of honour and examine how it promotes children’s wellbeing and or sustains violence against children in the Ugandan context.

USA 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jesca Nantume
ID: UNCST-2021-R013984
 Knowledge, attitudes and practices towards the tobacco use control measures among teenagers aged (13-19) years; A cross sectional study in the slum areas of Kampala Uganda
REFNo: SS988ES

To evaluate knowledge, attitudes and practices towards tobacco control among teenagers
aged (13-19) years
1. To evaluate existing control measures among teenagers
2. To assess the knowledge, attitudes, and practices of the current tobacco control
measures among teenagers.
3. To evaluate the cause of initiation of tobacco use in slums among teenagers
 Uganda 2021-09-03 2024-09-03 Social Science and Humanities Non-Clinical Trial Degree Award
Danette Cagnet Lee
ID:
Community-led Total Sanitation Programming and the Maintenance of Sanitation Behaviors
REFNo: SS737ES

The purpose of this qualitative, exploratory, case study research is to better understand stakeholder's, including village community members, village leadership, and CLTS practitioner, perceptions of the facilitators and hindrances to the maintenance of sanitation in the maintenance stage of Community-led Total Sanitation programming in Uganda, East Africa. This study seeks the perspective of and participation of village community stakeholders receiving the Community-led Total Sanitation intervention implemented by the non-governmental organization, Kibo Group International.
 USA 2021-09-02 2024-09-02 Social Science and Humanities Non-Clinical Trial Degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 Acute Leukemia Banking and Biology Study for Patients at the Uganda Cancer Institute.
REFNo: HS1590ES

1. To determine the genomic profile of patients with acute leukemia and identify the prevalence of various fusions and mutations in these patients.
2. To collect and store corresponding subjects’ medical information including diagnosis and disease characterization, laboratory and imaging studies, treatment, and outcome.

 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
John Baptist Asiimwe
ID: UNCST-2021-R013716
 The Traditional Medicine Practitioner’s Concept of Cancer, its Care, Herbal medicine use and the Patients Perceived benefits (Clinical outcomes) in Selected Districts of Central Uganda.
REFNo: HS1602ES

1. To establish the prevalence and predictors of the use of herbal medicines’ in cancer
2. To explore the concept of cancer and its care in traditional medicine as perceived by traditional medicine practitioners (TMPs) in selected districts of central Uganda
3. To document the herbs used by traditional medicine practitioners (TMPs) to manage cancer in selected districts of central Uganda.
4. To determine the clinical outcomes in patients with cancer treated by traditional medicine practitioners (TMPs).

 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses Adriko
ID: UNCST-2019-R001787
 Gaining community insights into societal causes of and solutions for schistosomiasis transmission hotspots (InSight-ScHot)
REFNo: HS1616ES

To identify non-mass administration preventative chemotherapeutic control measures for schistosomiasis that members of the community see as implementable
 Uganda 2021-09-02 2024-09-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Enock Matovu
ID:
Identification of the Genetic Markers of Trypanotolerance in Indigenous Cattle of Apach District, Northern Uganda
REFNo: NS247ES

Main Objective
To identify genetic markers of Animal African Trypanosomiasis (AAT) tolerance in indigenous cattle

Specific Objectives

i. To set up a panel of phenotypically characterized indigenous cattle with respect to AAT susceptibility

ii. To develop a data base of reference genomes and transcriptomes of indigenous cattle from an AAT endemic region of mid-northern Uganda
iii. To determine the genotypes associated with trypanotolerance in indigenous cattle

 Uganda 2021-08-31 2024-08-31 Natural Sciences Non-Clinical Trial Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Assessment of the Implementation Processes and Outcomes of the HIV Assisted Partner Notification Program, Ministry of Health, Uganda
REFNo: HS1671ES

3.2 General Objective
To assess the Implementation processes and outcomes of the HIV Assisted Partner Notification Program in Uganda
3.3 Study Objectives
1. To determine the current level of uptake of APN services and the factors associated with uptake of these services among HIV index clients.
2. To assess the acceptability and uptake of APN services among a sub-sample of partners of APN clients.
3. To assess the extent to which the existing service delivery environment influences the delivery of APN services.
4. To document the perceptions and experiences of users of APN services, challenges faced in utilizing APN services and concerns those users have regarding the way APN services are provided.
5. To determine the positive and negative outcomes of APN services in Uganda, and the support mechanisms available for those who experience negative outcomes.
6. To document the barriers to and facilitators of successful APN implementation and the challenges implementers face during APN implementation.
7. To document the existing opportunities that can inform the future scale-up of the APN program.

 Uganda 2021-08-31 2024-08-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A behavioural Science Research to Determine Factors that Facilitate Future Uptake of HIV Prevention Products and Multi-Purpose Prevention Technologies to Prevent HIV and Unwanted Pregnancy in Sub-Saharan Africa Universally Accessible HIV Prevention Technologies for African Girls and Young Women through Knowledge Applied from Behavioural Economics (UPTAKE)
REFNo: HS1540ES

Multi-purpose Prevention Technologies (MPTs) to prevent HIV and unwanted pregnancy in Sub-Saharan Africa

i. To understand facilitators of and barriers to uptake and retention of injectable and implantable long acting pre-exposure prophylaxis (LA-PrEP) and MPT to inform product development, using formative behavioural research methods
ii. To design interventions to impact the uptake of new biomedical HIV prevention products, as part of a suite of self-care and self-screening products for sexual and reproductive health, using quantitative behavioural research methods
iii. To test the effectiveness of the alternate design/interventions and strategies, using marketed LA contraceptive products as proxies for LA HIV prevention products in development
iv. To estimate the cost of retention interventions and the cost effectiveness of products and delivery methods among adolescent girls and young women (AGYW) and female sex workers (FSWs) for prevention of pregnancy and/or HIV, using modelling

 Uganda 2021-08-31 2024-08-31 Medical and Health Sciences Clinical Trial Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
 “Active Case Detection and Decentralized Dynamic Registry to Improve the Uptake of Rheumatic Heart Disease Secondary Prevention” (ADD-RHD)
REFNo: HS1561ES

Secondary objectives include technical proficiency, acquisition times, global image quality, and user satisfaction and confidence. Each of these parameters will be reported for the entire training group and a sub-group analysis will look for differences between curriculum groups. Acquisition times and image quality will be compared between trainees and expert sonographers.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
 Uganda 2021-08-30 2024-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Comfort Mukasa Hajra
ID:
Real-time access to sanitation information for improved management of sanitation services: A case Study in Kawempe division.
REFNo: HS1458ES

Main Objective:
To test if timely access to sanitation information leads to improved sanitation planning, increased access to safely managed sanitation services and improved multi-sectoral collaboration.

Specific Objectives:
1. To design and test the effectiveness of timely access to sanitation information for planning, coordination and access to improved sanitation services.
2. To validate user needs for sanitation service provision in Uganda.
3. To document scalable best practice mechanisms for improved multi-sectoral planning and coordination on sanitation.
 Uganda 2021-08-30 2024-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eric Awich Ochen
ID: UNCST-2021-R013266
 Preventing Gender-based Violence: Video Game Intervention Designed as an Educational Tool to Address Child Marriage in Uganda
REFNo: SS880ES

To assess the effectiveness of the game (Peace) in promoting pro-social attitude/behavior change and empathic capacity among young people to prevent violence.
• Help young people understand what sexual exploitation is and how it is linked to gender inequalities.
• Increase young people’s understanding about how adult power is misused to abuse and silence them.
• Show young people that perpetrators will seek out and exploit young women’s vulnerabilities.
• Help young people understand the impact that sexual coercion has on everyone involved.
• Empower young people in reporting incidents of child sexual abuse and sexual coercion.
• Increase awareness of the role of various agencies/individuals that can help.
• Help young people understand ways in which adults may groom them using various tactics.
• Help young people understand the relationship between sexual coercion and child marriage.
• Give young people the opportunity to develop skills, knowledge, and competencies that can help them make sound decisions for themselves or others in real life situations.
• To support and empower young people in avoiding child marriage


Uganda 2021-08-30 2024-08-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
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