Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Damari Atusasiire
ID: UNCST-2024-R002645
 A cluster- randomised controlled trial to assess the effectiveness and impact of the Tiko platform on increasing access to sexual and reproductive health (SRH) services among Adolescents and Young People (AYP) in Uganda
REFNo: SS3858ES

To assess whether the Tiko Model increases the modern Contraceptive Prevalence Rate (mCPR) among adolescents and young people in treatment areas relative to control areas.
To determine if there is a reduction in unintended pregnancies.
To evaluate improvements in knowledge, perceived norms, and attitudes towards contraception and HIV services (testing, ART, and PrEP).
To assess whether there is an increase in the uptake of HIV testing, ART, and PrEP.
To determine if there is an increase in access to high-quality, youth-friendly health services.
To examine whether there is a reduction in the HIV test positivity rate.
To assess improvements in the continued use of short-acting contraception and retention in ART and PrEP.
To evaluate whether there is an improvement in the number of Couple Years of Protection (CYP) offered.
 Uganda 2025-05-07 18:25:50 2028-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Victoria Isika Kiasyo
ID: UNCST-2025-R017083
 WOMEN'S DIGITAL SAFETY: Measurement for bolstering policy response
REFNo: SS3824ES

1. Conduct formative, human-centered research. We plan to co-create an instrument and contextualize our understanding of TFGBV, we will hold co-creation workshops with women and institutional stakeholders. 2. Translate formative human-centered findings to measurement. We will use qualitative insights from Aim 1 to compare local findings with existing TFGBV measures (developed mostly in high-income settings). 3. Pilot novel measure of TF-GBV exposure. We will pilot a quantitative instrument and submit this in an amendment to this ethics proposal. This amendment will specify the instrument, sampling, data collection procedures, analytical plan, community engagement and dissemination plan. Briefly, a long-list of items will be tested through quantitative surveys delivered both in person and digitally. Output from these surveys will enable us to validate and refine the instrument before dissemination.
 Kenya 2025-05-07 18:23:51 2028-05-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Winnie Kibone
ID: UNCST-2023-R008421
 Navigating Dual Diagnoses: Experiences of Individuals Living with Sickle Cell Disease and HIV in Uganda
REFNo: HS5859ES

1. To explore the experiences of people living with SCD and HIV in Northern and Central
Uganda
2. To determine indications for hospitalization, co-morbidities and clinical outcomes of
patients with SCD in Northern and Central Uganda
 Uganda 2025-05-07 18:22:49 2028-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Uganda Paediatric Antiretroviral Treatment study on uptake and long term outcomes on dolutegravir in Children and Adolescents living with HIV in Uganda (UP-ART DTG study).
REFNo: HS5830ES

Primary objectives: 1.To describe the uptake of DTG in the UP ART cohort and characteristics at start of dolutegravir (DTG)- based regimens (DBRs) 2.To describe mortality and loss to follow-up among CALHIV after start of DBRs 3.To assess the effectiveness of DBRs by assessing viral load (VL) response over time on DBR (viral suppression and viral failure) Secondary objectives: 4.To identify factors associated with viral failure 5.To assess the number/proportion of CALHIV discontinuing DTG and reasons for discontinuation 6.To assess changes in weight, height and body mass index (BMI) over time on DBR In analyses for Objectives 1-6, the key results will be presented overall and stratified by the following characteristics at start of DBR (where sufficient numbers n>20): a)Age at start of DBR: <2, 2 to <6, 6 to <12 and 12 to <20 years b)ART history and VL status at start of DBR: Naive, ART-experienced and suppressed (VL<1000 copies/mL), ART experienced and viremic (VL≥1000 copies/mL) and ART- experienced and unknown VL. The VL status is based on most recent measurement within 6 months of start of DBR. c)DTG regimen: DTG/ABC/3TC, DTG/TDF/3TC, other DTG-based regimen
Uganda 2025-05-07 18:21:47 2028-05-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
AGNES SANSA
ID: UNCST-2025-R017934
 MULTI-GENERATIONAL WORK ETHICS, INCLUSIVITY, DIVERSITY MANAGEMENT PRACTICES AND THE PERFORMANCE OF PUBLIC AGENCIES IN UGANDA
REFNo: SS3782ES

i. To establish the relationship between multigenerational work ethics and the performance of public agencies in Uganda. ii. To assess the influence of inclusivity in the relationship between multigenerational work ethics and the performance of public agencies in Uganda. iii. iii. To examine the effect of diversity management practices in the relationship between multigenerational work ethics and the performance of public agencies in Uganda. iv. iv. To determine the joint effect of multigenerational work ethics, inclusivity and diversity management practices on the performance of public agencies in Uganda.
Uganda 2025-05-07 18:19:31 2028-05-07 Social Science and Humanities Non-Clinical Trial Degree Award
Joel Ongom
ID: UNCST-2024-R015752
 Impact of Dichrostachys cinerea management interventions on Soil Properties and subsurface Macrofauna in Queen Elizabeth National Park, Uganda
REFNo: NS902ES

1. To determine the effect of management intervention on D.cinerea by excavation and burning on the physico chemical properties of soil.
2. To assess the effect D.cinerea management intervention in QENP on the abundance and diversity of above ground soil macrofauna
3. To assess the effect D.cinerea magement interventions in QENP on the abundance and divesity of below ground soil macrofauna

 Uganda 2025-05-07 18:17:57 2028-05-07 Natural Sciences Non-Clinical Trial Non-degree Award
Mohamed Farah Mohamud
ID: UNCST-2025-R016841
 EFFECTIVENESS OF INTRAVENOUS PETHIDINE VERSUS INTRAVENOUS TRAMADOL FOR PERIOPERATIVE ANALGESIA IN UTERINE EVACUATION PROCEDURES AT JINJA REGIONAL REFERRAL HOSPITAL
REFNo: HS5960ES

1. To assess the effectiveness of intravenous pethidine versus intravenous tramadol for perioperative analgesia in uterine evacuation procedure at Jinja Regional Referral Hospital
2. To compare the secondary outcomes encountered among women administered with intravenous pethidine versus those with Intravenous Tramadol for perioperative analgesia in uterine evacuation procedures at Jinja Regional Referral Hospital
3. To compare the level of patient satisfaction with intravenous pethidine versus Intravenous tramadol in uterine evacuation procedures at Jinja Regional Referral Hospital

 Somalia 2025-04-30 7:27:21 2028-04-30 Medical and Health Sciences Clinical Trial Degree Award
Lillian Wambuzi Ogwang
ID: UNCST-2021-R013189
 Evaluation of eye-tracking tests of affection and executive function among adolescents living with HIV in Kampala, Uganda version 3.0 dated 13 Mar 2025
REFNo: HS5920ES

1) to assess executive functioning and affect with three tests adapted to eye-tracking instrumentation
2) to correlate measures of eye-tracking with standardized mental health assessments

 Uganda 2025-04-30 17:55:08 2028-04-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Muriel Mac-Seing
ID: UNCST-2024-R005208
 The Together Project 2.0: Co-creation and co-evaluation of accessible and gender-sensitive sexual and reproductive health and rights education video series for and with youth in situations of vulnerability in Uganda and Bangladesh
REFNo: SS3812ES

1. To identify SRHR education gaps and needs for youth in situations of vulnerability with limited to no access to SRHR education programs, in Gulu, Uganda, and Dhaka, Bangladesh (Phase 1) 2. To co-develop with youth in situations of vulnerability inclusive SRHR education programs that are contextually adapted to their needs and realities, while considering accessibility, social acceptability, and available SRHR resources (Phase 2). 3. To co-evaluate the relevance of the co-developed SRHR education content and co-learn for improved adaptation through community feedback-seeking and to inform further dissemination strategies tailored to the specific needs and preferences of youth in Gulu, Uganda, and Dhaka, Bangladesh (Phase 3).
Canada 2025-04-30 17:51:45 2028-04-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
SSENYONJO  TADDEO BIRUNGI
ID: UNCST-2024-R002326
 EFFECT OF CLIMATE CHANGE ON THE SOCIO-ECONOMIC CONDITION OF SUBSISTENCE CATTLE FARMERS IN NAKASONGOLA DISTRICT,UGANDA.
REFNo: A593ES

1.3 Objectives of the Study 1.3.1 Major objective To examine the effects of climate change on the socio- economic condition of subsistence cattle farmers in Nakasongola district and propose an appropriate farmer adaptation strategy. 1.3.2 Specific objectives 1.To describe negative effects of climate change faced by subsistence cattle farmers in Nakasongola District. 2.To explore impact of climate change on the socio-economic conditions of subsistence cattle farmers in Nakasongola District. 3. To evaluate adaptation and coping practices of subsistence cattle farmers in Nakasongola District with the effects of climate change. 4.To develop an adaptation strategy to the effects of climate change relevant to subsistence cattle farmers in Nakasongola District.
Uganda 2025-04-30 17:47:19 2028-04-30 Agricultural Sciences Non-Clinical Trial Degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 KHB HIV I/II Ab RAPID TEST (REF: R-429-1-C-1 and REF: R-429-50-C-1 ): Part of the Diagnostic Sensitivity and Diagnostic Specificity
REFNo: HS5945ES

The objective of this evaluation is twofold. By collecting capillary whole blood (i.e. fingerprick) samples and corresponding venous whole blood (EDTA-K2) and plasma (EDTA-K2) samples the following objectives are assessed:
1) To establish the performance of the KHB HIV I/II Ab RAPID TEST using capillary whole blood or fingerprick samples when performed by lab technicians at an African hospital lab and by lay providers/healthcare workers (Nurses, Counsellors, clinical officers) at an African rural hospital lab.
2) To demonstrate specimen equivalence between capillary whole blood, venous whole blood and plasma.
This study will be conducted according to WHO TSS-1; Part 1 and part 2: Establishing clinical performance characteristics (professional use and/or self-testing.

 Uganda 2025-04-28 12:28:00 2028-04-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Justine  Komunyena Tumusiime
ID: UNCST-2023-R008465
 Assessment of the Country-Level Implementation and Use of Vaccine-Preventable Disease Surveillance Information Systems in the WHO African Region
REFNo: HS5798ES

To assess the current landscape of VPD surveillance systems across the 47 WHO AFRO member states, with a focus on system type, dreadiness, integration with broader health information systems, and identification of key gaps, needs, and opportunitiesigital ,
 Uganda 2025-04-28 12:19:35 2028-04-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 A Case Control Study to Assess Effectiveness and Safety of the R21/Matrix M Malaria Vaccine.
REFNo: HS5891ES

1) To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against
severe malaria caused by Plasmodium falciparum.

2) To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against
clinical malaria caused by Plasmodium falciparum in high-transmission
perennial areas.

3) To assess if the R21/Matrix-M vaccine recipients are at an increased risk of
death (all-cause).
Uganda 2025-04-25 9:46:49 2028-04-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Christine Semambo Sempebwa
ID: UNCST-2021-R011977
 Evaluation of Welcome Sesame: Inclusion and Belonging for Displaced Learners in Uganda
REFNo: SS3837ES

Objectives:

Main Objective
1. The main objective/ purpose of this study is to examine the effectiveness of the Welcome Sesame Program for Inclusion and Belonging for Displaced Learners in Uganda.

Specific Objectives
1. Objective 1: To Enhance the capacity of early learning settings to support inclusion and belonging for all learners in refugee and migrant-hosting communities.
2. Objective 2: To increase learners’ skills and dispositions towards equitable, inclusive, and pro-social behavior using the perspectives of caregivers/ parent educators, and other stakeholders as a reference.
3. Objective 3: To evaluate the process effectiveness from the perspective of different stakeholders, including partners, parents/ guardians and caregivers/ parent educators, about what is and is not working well under the different units of Welcome Sesame and identify what needs to be further refined prior to implementing subsequent interventions.
 Uganda 2025-04-24 12:45:39 2028-04-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peterson Kikomeko Kato
ID: UNCST-2019-R000881
 Ethnicity and Nutritional Status of Children Aged 0-59 Months in Kiryandongo and Kyangwali Refugee Settlement and Host Community
REFNo: HS5885ES

1.To assess the demographic characteristics of Congolese and South Sudanese refugees in Kyangwali and Kiryandongo refugee settlements and those of their host communities 2.To analyse the nutritional status of Congolese and South Sudanese refugee children 0-59 months in Kiryandongo and Kyangwali refugee settlements and those in their respective host communities 3.To analyse the infant and young child feeding practices of Congolese and South Sudanese refugee children 0-59 months in Kiryandongo and Kyangwali refugee settlements and those in their host communities 4. Investigate the influence of ethnicity on nutritional status (wasting and stunting) of Congolese and South Sudanese refugee children 0-59 months in Kiryandondo and Kyangwali refugee settlements 5.To establish the difference in the age of growth faltering between the children of Congolese and South Sudanese aged 0-12 months in Kiryandongo and Kyangwali refugee settlements 6.To establish the difference in the age of growth faltering between the children of Congolese and South Sudanese refugee children aged 0-12 months in Kiryandondo (mainly South Sudanese) and Kyangwali (mainly Congolese) refugee settlements
Uganda 2025-04-24 12:36:55 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Protazio Sande
ID: UNCST-2024-R002344
 EXPLORING THE ROLE OF BOARD GOVERNANCE IN ORGANIZATIONAL PERFORMANCE IN PUBLIC AGENCIES WITHIN UGANDA’S MINISTRY OF FINANCE, PLANNING, AND ECONOMIC DEVELOPMENT
REFNo: SS3855ES

The study aims to explore the role of board governance in enhancing organizational performance in selected public agencies under the Ministry of Finance, Planning and Economic Development in Uganda. It will investigate how board structure, board processes, and board practices influences the efficiency, effectiveness, and relevance of these organizations. The Specific Objectives are: 1. To analyze how different board structures impact the overall performance of public agencies. 2. To investigate the specific practices adopted by boards and their effects on the performance of public agencies. 3. To assess how various board processes contribute to the performance of public agencies. 4. To explore stakeholders’ perceptions about the effect of Board governance on Organizational performance.
 Uganda 2025-04-24 12:31:19 2028-04-24 Social Science and Humanities Non-Clinical Trial Degree Award
Andrew Seguya Ggunga
ID: UNCST-2025-R018111
 Mountain Gorilla Census in the Bwindi and Sarambwe Ecosystem
REFNo: NS955ES

The Mountain Gorilla Census is a survey that has been periodically conducted to determine the
minimum number of individual habituated and non-habituated mountain gorillas in Virunga
Bwindi Landscape. The census of mountain gorillas also helps us to understand the population
dynamics, including changes in gorilla groups composition and sizes as well as solitary males. In
addition, this survey provides the opportunity to determine levels of human disturbance as well as
the status of other large mammals in the landscape. The results from the census enable us to assess
the success of all conservation efforts aimed at protecting mountain gorillas and its habitats, as
well as to ensure that they receive continue attention from the global conservation community.

Uganda 2025-04-24 12:26:12 2028-04-24 Natural Sciences Non-Clinical Trial Non-degree Award
Robert Mugabe
ID: UNCST-2024-R004064
 DESIGN OF A FUZZY LOGIC FAULT DETECTION ALGORITHM AND AUTOMATIC PHASE SWITCHING IN ELECTRIC POWER TRANSMISSION
REFNo: NS954ES

1. To develop a model, using ABCD parameters, of a long transmisision line.
2. To obtain Surge impedance loading (SIL) curves for transmission line monitoring and
fault prediction.
3. To develop a fuzzy logic fault detection algorithm.
4. To simulate the developed model and the fuzzy logic algorithm using SIMULINK
 Uganda 2025-04-24 12:24:25 2028-04-24 Natural Sciences Non-Clinical Trial Degree Award
BRENDA GATI MIREMBE
ID: UNCST-2021-R013390
 Improving Choice and Use of Biomedical HIV Prevention for Women in Uganda: A Couples-Based Approach (CUPID)
REFNo: HS5827ES

Aim 3: To assess CUPID implementation outcomes, and barriers and strategies to address them, to inform the adoption and integration of CUPID to support women’s PrEP uptake and use.,Aim 2: Assess the effectiveness of the CUPID intervention on PrEP uptake, persistence, and use among Ugandan women, compared to PrEP choice delivered to women only.,Aim 1: To refine CUPID intervention content and implementation to support women’s PrEP choice and use in public health settings.,
 Uganda 2025-04-24 12:23:21 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pamela Apio Okwir
ID: UNCST-2022-R010419
 Acceptability of SMART pill bottle use among children with Rheumatic Heart Disease on oral penicillin prophylaxis in Lango Subregion, Uganda.
REFNo: HS5816ES

1. To assess the acceptability of children with RHD undergoing oral penicillin prophylaxis on use of SMART pill bottles in Lango subregion, Uganda. 2. To explore the perceptions of children with RHD undergoing oral penicillin prophylaxis on the use of SMART pill bottles in Lango subregion. 3. To determine the factors associated with acceptability of SPBs among children with RHD on oral penicillin prophylaxis
Uganda 2025-04-24 12:16:45 2028-04-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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