Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jacqueline Kyosiimire-Lugemwa
ID: UNCST-2022-R005393
 Epigenetic modifications in HIV-1 accessory and regulatory genes, Host genes and differential protein expression among LTNP and Rapid progressors from a Ugandan Cohort
REFNo: HS4047ES

Aim 1. Identify the differential expression of Epigenetic signatures of HIV-1 accessory and regulatory genes DNA methylation among African pediatric LTNP and Rapid progressors Aim 2. Identify the differential expression of Epigenetic signatures of the host genome DNA methylation among African pediatric LTNP and Rapid progressors. Aim 3. Identify the differential expression of plasma proteomic signatures among African pediatric LTNP and Rapid progressors. Aim 4. Establish protein-protein interactions and metabolite interaction networks among African pediatric LTNP and Rapid progressors.
 Uganda 2024-05-23 14:57:54 2027-05-23 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Achan Edwin
ID: UNCST-2023-R005498
 Evaluation of the protective efficacy of a spatial repellent to reduce malaria prevalence in Uganda: Study protocol for a cluster-randomized double-blinded control trial: The Mossie-GO trial
REFNo: HS4196ES

The study’s primary objective is to demonstrate and quantify the protective efficacy (PE) of Mossie-GO, an active spatial repellent system disseminating transfluthrin, in reducing the prevalence of malaria infection in children ? 5 years of age.

The study’s secondary objective is to measure the impact of the intervention on entomological correlates of transmission including vector densities and host seeking behaviour. Insecticide resistance in the local mosquito population will also be explored.

Uganda 2024-05-23 14:23:11 2027-05-23 Medical and Health Sciences Clinical Trial Non-degree Award
Tonny Oyana Justus
ID:
A HOLISTIC APPROACH IN MANAGEMENT AND SURVEILLANCE OF LOWER RESPIRATORY TRACT INFECTIONS (LRTIS) THROUGH CONVERGENCE OF DIAGNOSTIC TECHNOLOGIES, CAPACITY BUILDING AND STAKEHOLDER ENGAGEMENT (HOLICARE)
REFNo: SIR330ES

1. To survey and describe the existing diagnostics approaches/ technologies applied in Uganda’s health System specifically for lower respiratory tract infections.
2. To develop an ICT-based medical data flow network
3. To validate the framework using diagnostic mobile API’s
 Uganda 2024-05-23 14:00:03 2027-05-23 Engineering and Technology Non-Clinical Trial Non-degree Award
Enerst Edozie
ID: UNCST-2023-R005516
 DEVELOPMENT OF A MONITORING AND DETECTION PIPELINE FOR HUMAN ACTIVITIES AROUND TELECOMMUNICATIONS INFRASTRUCTURE USING ARTIFICIAL INTELLIGENCE - KIU-2023-280
REFNo: SIR337ES

4. To validate the developed system using publicly available human activity datasets. ,3. To design and implement an embedded sensor and alarm systems to curb theft and vandalism of optical fiber cable., 2. To develop a real-time artificial intelligent system based on YOLO Deep Learning for monitoring and detection of activity around an optical fiber cable. ,1. To develop anomaly activities datasets of pedestrians activity around telecoms infrastructure. ,This study aims to implement an efficient monitoring and detection of abnormal activities around telecommunications infrastructure using artificial intelligence based approach. ,
 Nigeria 2024-05-23 13:58:11 2027-05-23 Engineering and Technology Non-Clinical Trial Degree Award
Godfrey Ejuu
ID: UNCST-2021-R013978
 Scaling Inclusive Home-based Early Learning Initiative (SIHELI): Lessons from Uganda, Ghana and Liberia
REFNo: SS2607ES

3. Mobilize the knowledge and evidence on the scaled inclusive early learning play approaches to improve policy and practice in education systems.,2. Strengthen the capacities of parents, teachers, education officials and community members to support and sustain the use of play pedagogy in the established home based early learning centres. ,1. Generate knowledge and evidence on how to scale the impact of inclusive home based early learning approaches to promote inclusive early learning and school readiness. ,The project’s general objective is to generate evidence to contextualize and scale the impact of inclusive home-based early learning play approach to promote smooth transition from ECCE to primary school.,
 Uganda 2024-05-23 13:56:14 2027-05-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
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