Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Damalie Nalwanga
ID: UNCST-2021-R013217
Exploring understanding, attitudes and practices of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in children in the context of COVID-19
REFNo: SS803ES

1.To assess the level of understanding of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in the context of COVID -19
2.To assess the attitudes of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in the context of COVID -19
3.To assess the practices of frontline health workers and caretakers regarding the relationship between severe pneumonia and malnutrition in the context of COVID -19

Uganda 2021-06-16 2024-06-16 Social Science and Humanities Non-degree Award
Emmy Okello
ID: UNCST-2020-R009792
Active Case Detection and Decentralized Dynamic Registry to Improve the Uptake of Rheumatic Heart Disease Secondary Prevention (ADD-RHD)
REFNo: HS1323ES

Primary Objective:
To develop and refine a technology-enabled approach to increase uptake of secondary prevention (ADD-RHD) that is sustainable and replicable at scale to improve outcomes for people living with RHD.

Secondary Objectives:
Aim 1: Optimize the ADD-RHD ACT Platform to maximize case retention and delivery of secondary prophylaxis.
Aim 2: Roll out and evaluate the implementation of the ACT Platform.
Aim 3: Assess the adequacy of current policy and regulatory guidance in Uganda for the adoption of new technologies for health in general, and for rheumatic heart disease diagnosis and management and to describe system and policy constructs necessary for the successful approval of new health technology.
Aim 4: Estimate costs, cost-effectiveness, and budget impact of the ACT platform intervention.

Uganda 2021-06-16 2024-06-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Julius Okuni Boniface
ID: UNCST-2019-R000963
A MULTI-COUNTRY, SINGLE-BLINDED, PHASE 2 STUDY TO EVALUATE RAPID DETECTION SYSTEMS OF SARS-COV-2
REFNo: HS1425ES

1. To determine the clinical sensitivity of the test assays compared to the real-time RT-PCR-based method.
2. To determine the specificity of the test assays compared to the real-time RT-PCR-based method.

Uganda 2021-06-16 2024-06-16 Medical and Health Sciences Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
The effect of household air pollution on lung function recovery in COVID-19 disease
REFNo: SS892ES

Main objective
- The overall aim of the study is to measure the effect of air pollution on lung function recovery after COVID-19 pneumonia.

-Measure the effect of air pollution exposure on lung function recovery after COVID-19.

Specific Objectives

- Measure the effect of mobility on air pollution exposure and lung function recovery after COVID-19.
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Uganda 2021-06-16 2024-06-16 Social Science and Humanities Non-Clinical Trial Non-degree Award
Moses  Mulumba
ID: UNCST-2021-R013832
An Ethnographic Analysis of the Right to Health Based Monitoring of and Advocacy for the Progressive Realization of Universal Health Coverage in Uganda
REFNo: SS793ES

Study Goal

The goal of the project is to establish the extent to which OPERA plus PAR supports the localization of the right to health

Specific objectives
To build the capacity of civil society and influential academia on the use of the OPERA framework

To explore the current levels of enjoyment of the right to health in Uganda

To assess state commitments and efforts to fulfill the right to health including the use of adequate resources

To examine constraints to the state's compliance to fulfill the right to health.
Uganda 2021-06-14 2024-06-14 Social Science and Humanities Non-Clinical Trial Non-degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
Establishing the prevalence of COVID19 infection among patients attending TB clinic, and the effect of COVID19 on TB clinical care in Kampala
REFNo: HS1304ES

Primary objective: 1. To determine the prevalence of COVID-19 infection amongst adult patients attending TB clinics Secondary objectives 1. To determine the prevalence of previous COVID-19 infection amongst adult patients attending TB clinics 2. To explore the experiences of patients attending TB clinic during the COVID-19 pandemic 3. To explore the experiences of healthcare workers in relation to TB care provision during the COVID-19 pandemic
Uganda 2021-06-11 2024-06-11 Medical and Health Sciences Non-degree Award
Arthur Bagonza
ID:
EFFECTIVENESS OF SUPPORT GROUPS ON IMPROVING LIVELIHOOD OF PEOPLE WITH ALBINISM IN UGANDA
REFNo: SS882ES

1. To map and profile all PWA and service providers of PWA in three regions (Northern, Western and Central) Uganda.

2. To construct a model of group support for PWA in three regions of Uganda based on views of PWA.

3. To determine the effectiveness of support groups on increasing access to services and inclusion of People with Albinism in mainstream development processes in Uganda.

4. To explore perceptions of key stakeholders on the use of support groups in increasing access to services and inclusion in mainstream development processes for PWA in Uganda


Uganda 2021-06-11 2024-06-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Romeo Gichohi wahome
ID:
EFFECTIVENESS OF IMPROVISED CARDBOARD SPLINTS AS AN ALTERNATIVE TO PLASTER OF PARIS IN THE EMERGENCY TREATMENT OF LOWER LIMB FRACTURES
REFNo: HS1357ES

General Objective
1. To determine whether improvised cardboard
splints are a viable effective
alternative to plaster of Paris splints
for lower limb fractures in Mbarara
Regional and Referral
Hospital.
Specific Objectives
1. To compare the clinical effectiveness of immobilization between improvised cardboard
and plaster of Paris splint in lower limb fractures.
2. To compare the time and resource costs between improvised cardboard and plaster of
Paris in splinting of lower limb fractures.
Kenya 2021-06-11 2024-06-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Dennis Muhanguzi
ID: UNCST-2019-R001101
Accelerating Anti-Tick Vaccine Production Using Computational Approaches and Validation with An In-Vivo Model
REFNo: NS165ES

The specific objectives of this study will be to;
i.Create an open access queryable database of candidate anti-tick vaccine protein from I. scapularis proteome
ii.Identify single and chimeric antigenic anti-tick peptides basing on tick-specific amino acid sequences
iii.Evaluate the immunogenicity of five of the most promising antigenic single and chimeric anti-tick peptides in a laboratory animal [three months New Zealand rabbits] model
Uganda 2021-06-10 2024-06-10 Natural Sciences Non-degree Award
Jerome  Kabakyenga Kahuma
ID: UNCST-2021-R013729
Smart discharges to improve post-discharge health outcomes in children below 6 months old
REFNo: SS855ES

To determine the effectiveness of a Smart Discharge program on post-discharge health seeking behavior and mortality among children under 6 months of age admitted with a proven or suspected infection.
Uganda 2021-06-08 2024-06-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
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