Grace Kisitu Paul
ID: UNCST-2024-R004102
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DPART STUDY: DIHYDROARTEMISININ-PIPERAQUINE IN THE CONTEXT OF ANTIRETROVIRAL THERAPY
REFNo: HS486ES
OVERALL AIM: To determine the PK/PD of DP in HIV-infected children in the setting of first-line ART regimens including LPV/r, EFV and potentially the integrase inhibitor dolutegravir (DTG) which may become widely used in older Ugandan children.
Our primary objectives are:
PRIMARY OBJECTIVES:
1) To evaluate and compare the PK exposure and safety of single dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L1 vs C1)
2) To evaluate and compare the PK exposure and safety of 3-dose DP in HIV-infected children on LPV/r-based ART to HIV-uninfected children not on ART (Group L3 vs C3a)
3) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on EFV-based ART and HIV-uninfected children not on ART (Group E3 vs C3a).
4) To evaluate and compare the PK exposure of 3-dose DP in HIV-infected children on DTG-based ART and HIV-uninfected children not on ART (Group D3 vs C3b).
SECONDARY OBJECTIVES:
1) The effects of DP on antiretroviral PK in the above 3-dose arms (EFV, DTG, LPV/r and controls)
2) To evaluate the association of anthropomorphic indicators of malnutrition on PK exposure of DP in HIV-infected and HIV-uninfected children
3) Assess auto-induction of DHA from single dose to 3-dose
4) To assess the prevalence of pharmacogenetic variants in key metabolic enzymes, including UGT1A1, CYP2B6, CYP3A4, and ABCB1, and the impact of these variants on ACT and ART PK.
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Uganda |
2020-02-06 |
2023-02-06 |
Medical and Health Sciences |
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Non-degree Award |
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Margaret Lubwama
ID: UNCST-2019-R000636
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Prevalence of multidrug resistant bacteria carriage on mobile phones of final year medical students at Makerere University College of Health Sciences
REFNo: HS491ES
1. To determine the prevalence of multidrug resistant bacteria on mobile phones of final year medical students at Makerere University College of Health Sciences.
2. To determine risk factors associated with multidrug resistant bacteria carriage on mobile phones of final year medical students at Makerere University College of Health Sciences
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Uganda |
2020-02-06 |
2023-02-06 |
Medical and Health Sciences |
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Non-degree Award |
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Ryoma OTSUKA
ID:
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Study on Sustainability of Mountain Gorilla Tourism: From a Tourism Management Perspectives
REFNo: SS387ES
The aim of this study is to contribute to the sustainable development of mountain gorilla tourism in Uganda. We have three main objectives of our study. The first one is to better understand tourist needs or expectations and how it is engendered in relation to information sources. The second one is to better understand and explore factors that affect tourist satisfaction. The third one is to understand rangers’ perception of mountain gorillas, gorilla tourism, and tourists.
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Japan |
2020-02-06 |
2023-02-06 |
Social Science and Humanities |
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Degree Award |
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Amy Young
ID:
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Causes of under-five child mortality in the slum communities of Kampala, Uganda: A Verbal and Social Autopsy Study
REFNo: HS507ES
The study seeks to identify the biomedical causes of death as well as the sociodemographic, behavioral and environmental factors associated with child mortality in the slum communities of Kampala. This includes recognition of illness, decisions around care-seeking, and care-seeking behaviors.
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USA |
2020-02-06 |
2023-02-06 |
Medical and Health Sciences |
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Non-degree Award |
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Othman Kakaire
ID: UNCST-2019-R000359
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A randomized controlled trial of copper and levonorgestrel intrauterine contraceptive devices among postpartum women in Uganda.
REFNo: HS337ES
Primary Objective:
1)To determine if there is a difference in expulsion rates at twelve months in women randomized to have the Levonorgestrel or copper intrauterine devices inserted in the immediate postpartum period (defined as after delivery of placenta to 48 hours postpartum).
Secondary objectives:
1.To explore women’s perceptions of postpartum contraception
2.To compare discontinuation rates of LNG-IUS and Copper IUD at 12 months
3.To compare pregnancy rates between the two arms at 12 months
4.To compare patterns of vaginal bleeding between the two arms
5.To compare contraceptive satisfaction between the two arms at 3, 6 and 12 months
6.To compare time from delivery to lactogenesis between the two arms
7.To compare breastfeeding over the initial 6 months between the two arms
8.To compare the change in infant weight, length and head circumference from delivery to 6 weeks and from delivery to 6 months between the two arms
9.To compare adverse events including but not limited to uterine perforation, pelvic infection, IUC expulsion, thromboembolism, and death between the two arms
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Uganda |
2020-01-29 |
2023-01-29 |
Medical and Health Sciences |
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Non-degree Award |
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Abubakar Mustafa Sadik
ID:
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Mechanisms of defense against Xanthomonas campestris pv. musaceurum infection in banana cultivars
REFNo: NS107ES
1. To determine whether callose induction is an effective measurable defense output in banana immune response to Xcm infection.
2. To identify the differentially regulated genes during Xcm-banana interaction.
3. To identify differentially regulated metabolites during Xcm-banana interaction.
4. To determine the spatial-temporal distribution of Xcm in banana tissues
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Uganda |
2020-01-21 |
2023-01-21 |
Natural Sciences |
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Degree Award |
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Joseph Rwothumio
ID:
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RELATIONSHIP BETWEEN HUMAN RESOURCE MANAGEMENT PRACTICES AND ACADEMIC STAFF PERFORMANCE IN SELECTED
PUBLIC UNIVERSITIES IN UGANDA
REFNo: SS400ES
This study endeavored to:
1.Establish the relationship between training and academic staff teaching output in selected public universities in Uganda.
2.Establish the relationship between training and academic staff research output in selected public universities in Uganda.
3.Examine the relationship between financial reward and academic staff teaching output in selected public universities in Uganda.
4.Examine the relationship between financial reward and academic staff research output in selected public universities in Uganda.
5.Determine the relationship between performance appraisal and academic staff teaching output in selected public universities in Uganda.
6.Determine the relationship between performance appraisal and academic staff research output in selected public universities in Uganda.
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Uganda |
2020-01-21 |
2023-01-21 |
Social Science and Humanities |
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Degree Award |
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Nicholas Penny Gordon
ID:
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Conserving the Gorillas of Bwindi
REFNo: NS111ES
The objectives of this project are:
- to create a complete photo-story and short film about the work of UWA, CTPH and local communities around Bwindi. This will include gorilla treks, the process of finding the gorillas, sample collections from gorilla night nests, how samples are used/analyzed to determine the health of the individuals within a troop and the work in the CTPH Gorilla Health and Community Conservation Center.
- to support UWA and CTPH by giving all photographs and the completed film to them free of charge at the end of the research period;
- to celebrate Uganda’s commitment and role at the forefront of gorilla conservation;
- to support UWA and CTPH and promote the work they do, showing the care and dedication of people who work directly with the gorillas and local people.
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UK |
2020-01-21 |
2023-01-21 |
Natural Sciences |
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Degree Award |
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Benson Oloya
ID:
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Phytochemistry, Antitubercular activity and Cytotoxicity of Selected Plant Species used for the Treatment of Tuberculosis in Uganda
REFNo: NS112ES
i. To isolate and carry out structure determination of the compounds from the four plant species selected,
ii. To investigate the antitubercular activity of the crude extracts and compounds from the four plant species selected,
iii. To determine the cytotoxicity of the crude extracts
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Uganda |
2020-01-21 |
2023-01-21 |
Natural Sciences |
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Degree Award |
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FAITH NATUKUNDA
ID:
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Optimisation of Thermal and Power Requirements of Resistive Coil-based Low Field MRI Systems
REFNo: SIR24ES
1. Examine the methods of cooling that have been applied in thermal management of resistive coil systems
2. Examine the power and thermal limits of Low field MRI systems
3. Design and numerically analyze a cooling system for a low field MRI system
4. Validate numerical results using experimental data
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Uganda |
2020-01-21 |
2023-01-21 |
Engineering and Technology |
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Degree Award |
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