Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Moses Joloba Lutaakome
ID: UNCST-2022-R011558
Advancing Tissue and Organ Biobanking in Uganda
REFNo: HS572ES

General objective: To establish a tissue and organ biobank at Makerere University to serve as a catalyst for research in organ collection, biobanking and transplantation in Uganda.
Specific Objective :
1. To train personnel and develop standard operating procedures for collection, processing and storage of human ova, sperm and umbilical cord blood.
2. To collect, process and store human ova, sperms and umbilical cord blood.
3. To develop a publicly accessible catalog of HLA typed viable human tissue and organs.
4. To explore the ethical, legal and societal issues (ELSI) in human tissue and organ biobanking

Uganda 2020-03-03 2023-03-03 Medical and Health Sciences Non-degree Award
ROSE ATIM
ID:
Law, Culture and Reality: Women Navigating Post Conflict Marital Relations in Northern Uganda
REFNo: SS423ES

1. Investigate the legal implication of the institution of marriage on women born in internally displaced peoples camps and victims of sexual violence of the LRA conflict;
2. Interrogate if cohabitation as an alternative to ‘legal’ marriage is becoming institutionalized among women born in internally displaced peoples camps and victims of sexual violence of the LRA Conflict;
3. Analyse the effectiveness of legal and informal marital protection mechanisms in a post conflict society;
4. Interrogate the future of the law in customary marital unions.

Uganda 2020-03-03 2023-03-03 Social Science and Humanities Degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
SAFETY AND EFFICAY OF DOLUTEGRAVIR AND EFV 400 FOR PREGNANT AND BREAST FEEDING WOMEN; A RANDOMISED NON INFERIORITY CLINICAL TRIAL ACRONYM: PREGART
REFNo: HS515ES

PRIMARY OBJECTIVE; to identify safer and more effective ART regimen for pregnant and breast feeding women by comparing three alternative first line ART regimens for their safety and efficacy using randomized clinical trial.

SECONDARY OBJECTIVE; To provide evidence based recommendations for safe and effective first line ART regimens for prevention of mothers to child transmission and treatment of HIV infected pregnant and breast feeding women living in resource limited setting.

Uganda 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
Coleen Sabatini
ID: UNCST-2019-R001321
Outcomes Following Surgical Release of Gluteal Fibrosis in Children of Eastern Uganda
REFNo: HS561ES

This study is a longitudinal case series to evaluate if surgical release of gluteal fibrosis in Ugandan children has a sustained benefit. We will examine the two-year outcomes after surgical release of gluteal fibrosis in children undergoing surgical intervention for gluteal fibrosis.

USA 2020-02-25 2023-02-25 Medical and Health Sciences Non-degree Award
NAASSON TUYIRINGIRE
ID:
Metabolomics Approaches to Elucidate the Mechanisms of Action of Antimycobacterial Medicinal Plants
REFNo: HS422ES

The main objective is to elucidate the mechanisms of action of antimycobacterial medicinal plants using metabolomics. The specific objectives are:
1. To determine the metabolome of M.tb subjected to medicinal plant extracts with antimycobacterial activity as compared to control culture
2. To optimize an analytical metabolomics workflow to facilitate reproducible measurements of bacterial metabolome with extract treatment or without the treatment
3. To elucidate the metabolic pathways affected by plant extracts
4. To identify the macromolecule targets of plant extracts

Rwanda 2020-02-21 2023-02-21 Medical and Health Sciences Degree Award
Jean Damascene Niyonsenga
ID:
Exercise and well-being: NCD risks and constraints to Physical Activity and sports participation among Ugandan rural and urban secondary school students
REFNo: HS490ES

1. To examine the correlation between NCDs risk factors and level of physical activity/sports participation, type of eaten food, and lung function among both rural and urban secondary school students in Mbarara, uganda
2. To establish constraints to PA/sports participation of secondary school students in rural and urban schools in Mbarara, Uganda.
3. To examine the relationship between internal motivation and external support for PA/sports participation for secondary school students in rural and urban schools of Mbarara, Uganda.
4. To determine the commonest sustained injuries and to establish the proportion attributable to PA/sports among rural and urban secondary school students in Mbarara, Uganda.
5. To compare constraints and injuries identified by secondary school students from rural and urban schools in Mbarara, Uganda.

Rwanda 2020-02-21 2023-02-21 Medical and Health Sciences Non-degree Award
Robert Kairania
ID:
Exploration of psychological distress and cross-cultural adaptation of a mental health measure for people living with HIV in Rakai, Uganda
REFNo: SS408ES

Aim 1: To characterize local manifestations of psychological distress among people living with HIV in rural communities in Rakai, Uganda

Aim 2: To identify and cross-culturally adapt appropriate mental health measurement instruments based on findings from Aim 1.

Aim 3: To validate the adapted mental health measurement instrument within the rural Rakai population.

Uganda 2020-02-21 2023-02-21 Social Science and Humanities Non-degree Award
Vincentina Achora
ID:
Postpartum haemorrhage in Northern Uganda: Community perspectives; burden and associated factors; Health Facilities preparedness for its management; and outcomes
REFNo: HS518ES

1. To explore the community perspectives of PPH in Lira district.
2. To assess the level of health facilities preparedness for management of labour, delivery and postnatal care in prevention of PPH in Lira district.
3. To describe the burden and factors associated with PPH among mothers delivering in Lira district and Lacor Referral hospital.
4. To describe the factors associated with outcomes of PPH among mothers delivering in Lira district and Lacor Referral hospital.

Uganda 2020-02-21 2023-02-21 Medical and Health Sciences Degree Award
Maria Nakku Elizabeth Mirembe
ID:
Women in Higher Education: An Ethnographic Case Study of Women Lecturers and Administrator Experience in Selected Universities in Uganda
REFNo: SS410ES

1. To investigate how women lecturers and administrators advance the institutional mission of teaching, scholarship, and service in selected universities in Uganda
2. To explore how the culture of higher education shape and affect women leadership
3. To examine the obstacles and challenges do women experience as lecturers and administrators in higher education
4. To assess common attributes and strategies support women’s success in higher education teaching and administration in Uganda


Uganda 2020-02-21 2023-02-21 Social Science and Humanities Degree Award
Lawrence Mugisha
ID:
Developing Monitoring System for Quantifying and Mapping Antimicrobials used in Livestock Farming Systems in Uganda
REFNo: HS538ES

1. To determine the proportions of different types of antimicrobials imported into Uganda for use in livestock production systems.
2. To determine the volumes of antimicrobial medicines imported into Uganda for use in livestock production systems.
3. To map and create an inventory of manufacturers, importers, distributors and medicine stockists of antimicrobials used in livestock production systems in Kampala, Wakiso and Mukono districts.
4. To develop an information technology (IT) monitoring system for monitoring importation, distribution and consumption of antimicrobials used in livestock production systems

Uganda 2020-02-21 2023-02-21 Medical and Health Sciences Non-degree Award
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