Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Infant Malaria following IPTp with Artemisinin-based Combination Therapy (IMPACT)
REFNo: HS1819ES

To compare the incidence of malaria from 4 weeks to 1 year of age among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

To determine whether infant sex modifies the association between maternal IPTp regimen and the incidence of malaria from 4 weeks to 1 year of age.

To compare innate and adaptive effector and regulatory responses among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

Uganda 2021-11-05 2024-11-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Laban Musinguzi Kashaija
ID: UNCST-2020-R014407
 Midterm Review of the Higher Education Access Program
REFNo: SS1067ES

1. Assess the extent to which the expected short and intermediate outcomes of the program have been achieved;
2. Review program implementation effectiveness as well as draw interim lessons that can help optimize the Program’s impact going forward.
Uganda 2021-11-05 2024-11-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Velma  Kivali Majani
ID:
Microbial contamination at slaughter and retail points of the pork value chain in Uganda
REFNo: HS1820ES

1.To determine the prevalence and associated risk factors for non-typhoidal Salmonella infection among meat handlers in the pork value chain in selected cities in Uganda 2.To determine prevalence of non-typhoidal Salmonella in pig carcasses and pork at various points in the pork value chain and to evaluate risk factors associated with those prevalences in selected cities in Uganda 3.To determine the levels of contamination with coliforms in pig carcasses and pork at various points in the chain and evaluate risk factors associated with those levels in selected cities in Uganda 4.To characterize non-typhoidal Salmonella from swine, humans and the slaughter/retail environments in Uganda and determine the potential for pig to transmission.
Kenya 2021-11-03 2024-11-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Irene  Nakatudde
ID:
Excessive weight gain and associated factors in HIV-infected adolescents on dolutegravir-based antiretroviral therapy in Kampala, Uganda
REFNo: HS1837ES

1. To determine the prevalence of excessive weight gain in HIV-infected adolescents on DTG-based ART attending KCCA health centres in Kampala.
2. To identify the factors associated with excessive weight gain in HIV-infected adolescents on DTG-based ART attending KCCA health centres in Kampala.

Uganda 2021-11-03 2024-11-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Secondary Research of MUWRP Sepsis Study Biospecimens: UNC 1 Evaluation of a Lateral Flow Immunoassay for Measuring Covid-19 Antibodies and 2 Related Inflammatory Biomarkers
REFNo: HS1821ES

The objective of the UNC study is to understand if the nonpowered lateral flow assay technology is as accurate as the powered GenScript SARS-CoV-2 surrogate virus neutralization test in detecting COVID-19 infection
 Uganda 2021-11-02 2024-11-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
James Kisambu
ID:
Uganda Prisons Service Project Evaluation Protocol
REFNo: HS1307ES

Objectives of UPS Program Evaluation
i. To evaluate the targeted HTC models to improve earlier identification of HIV-positive and negative individuals, and linkage of people living with HIV (PLHIV) in prisons community and facility sites and linkage and promotion of HIV prevention among HIV-negative individuals
ii. To evaluate innovative approaches that increase adherence, ART retention, and viral load (VL) suppression among adult and pediatric HIV clients.
iii. To determine if there is improved identification of TB-infected individuals, effective scale up of comprehensive TB/HIV services at individual sites, and progress towards reduction of TB burden among HIV/TB co-infected clients within the CDC-supported prison facilities
iv. To evaluate innovative PMTCT & HEI approaches that increase identification of HIV-positive and syphilis-infected pregnant & breastfeeding women (PBFW), enhance immediate ART uptake, adherence and retention, VL suppression and syphilis treatment among PBFW, reduce MTCT rates of HIV and syphilis and ensure documentation of 18 month final outcome status for all HEIs
v. To evaluate innovative interventions that are designed to improve data quality and data utilization for program evidence-based decision making at the facility level
vi. To determine if the strengthening of the existing laboratory network and its quality management systems increased the ART initiation and ART monitoring at the facility level.
vii. To determine the relationship between regional prison level performance reviews and human resource (HR) performance on facility performance including access, coverage, retention and loss to follow up.


 Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emmanuel Sendaula
ID: UNCST-2020-R014767
 Isoniazid preventive and antiretroviral therapy-associated Pellagra: A case series of Reach Out Mbuya.
REFNo: HS1474ES

To describe the clinical manifestations of patients on Isoniazid preventive and antiretroviral therapy presenting with pellagra 2. To review the health outcomes of patients on Isoniazid preventive and antiretroviral therapy presenting with pellagra particularly as related to INH withdrawal
Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Ifeagwu
ID:
The perceptions and values of multisectoral stakeholders related to universal health coverage (UHC) in Uganda
REFNo: HS1478ES

General objective:
To explore the perceptions, understanding and importance of achieving universal health coverage (UHC) by key stakeholders in Uganda.


Specific objectives:
a. To establish and enumerate the perceived importance being given to UHC as well as key barriers and challenges to achieving UHC in Uganda by national, regional and international health policymakers.
b. To understand local healthcare workers’ awareness and perceptions of UHC and examine differences between the views of urban and rural healthcare workers.
c. To determine the urgency, need, perceived impact (against the Sustainable Development Goals) placed on UHC by stakeholders, including policymakers and healthcare workers.
d. To use generated evidence to develop a policy brief using case examples highlighting promising approaches to support multisectoral UHC collaboration.

 Austria 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Theopista Fokukora
ID:
IMPROVING ACCESS AND USE OF EMERGENCY CONTRACEPTION AMONG ADOLESCENTS IN THE TOORO SUB-REGION OF UGANDA
REFNo: HS1829ES

1. To assess the prevalence of EC use among adolescents in Tooro Sub-region, Uganda
2. To investigate the individual factors associated with ECs use among adolescents in Tooro Sub-region, Uganda.
3. To investigate the community-based socio-economic and cultural factors associated with EC use among adolescents in Tooro Sub-region, Uganda.
4. To assess the health system and service provider factors associated with the provision of ECs to adolescents in Tooro Sub-region, Uganda.
5. To determine the effect of a reproductive health education intervention on knowledge, attitude, and practices of providers as well as utilization of EC among adolescents.

Uganda 2021-11-01 2024-11-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Paul Bangirana
ID:
Developing the Uganda National Mental Health Response to Disasters
REFNo: SS995ES

To design a national mental health response for disasters,To evaluate the cost effectiveness of implementing the intervention,To identify enabling factors for implementing the intervention in the relevant government ministries (acceptability),To identify barriers to implementation of the intervention in the community (feasibility),a)To develop a psychosocial intervention for victims, their families and health care workers during disasters,
 Uganda 2021-10-28 2024-10-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mary Acanit
ID:
Use of electronic library resources by postgraduate students in the Faculty of Engineering at Kyambogo University in Uganda
REFNo: SS948ES

To examine the use of electronic library resources by postgraduate students in the Faculty of Engineering at Kyambogo University in Uganda, with a view of suggesting a model to improve the use of those resources among engineering students.
 Uganda 2021-10-28 2024-10-28 Social Science and Humanities Non-Clinical Trial Degree Award
Namulema Edith
ID:
Effectiveness of the ‘LeVe CPAP’ against the standard AIRVO CPAP among Covid-19 patients with Acute Hypoxemic Respiratory Failure at Mengo Hospital Kampala Uganda: A Cross-Over Randomised Trial.
REFNo: HS1647ES

The main objective of the trial is to compare the clinical effectiveness of the LeVe CPAP device to the standard AIRVO CPAP in the delivery and maintaining continuous positive airway pressures among patients diagnosed with AHRF at Mengo Hospital Uganda.
 Uganda 2021-10-28 2024-10-28 Medical and Health Sciences Clinical Trial Non-degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 Optimizing Performance of the Human Powered Nebulizer Prototype; Exploring stakeholder perceptions towards the human-powered nebulizer
REFNo: HS1433ES

We aim to explore the perceptions towards the human-powered nebulizer by the stakeholders (health care workers, village health teams and caregivers).
Uganda 2021-10-27 2024-10-27 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Paul Mukasa
ID: UNCST-2021-R013464
 Antirabies compounds in Selected Medicinal Plants used in the Treatment of Rabies in Uganda
REFNo: NS290ES

Mian objective: To explore the medicinal plants used in the treatment of rabies for bioactive potential and phytochemical compounds as possible leads to antirabies agents in Uganda. Specific objectives: 1. To carry out an ethnobotatical survey on plant species used to treat rabies in Uganda. 2. To determine the cytotoxicity of the crude extracts of the selected plants used to treat rabies. 3. To determine the antirabies potency of the crude extracts of selected plants against rabies virus. 4. To elucidate the structure of the antirabies compound(s) isolated from the most bioactive portion(s).
 Uganda 2021-10-27 2024-10-27 Natural Sciences Non-Clinical Trial Degree Award
Kenneth Odur
ID:
Youth Public Health Ambassadors Community Health Assessment 2021
REFNo: SS1025ES

Collect information on sanitation and hygiene, nutrition, health and safety, and preventive health services present at primary and secondary schools located in participating communities surrounding Lira, Uganda.,Collect information on existing health care services and infrastructure present at health facilities in participating communities surrounding Lira, Uganda.,Collect data on health behaviors, knowledge and attitudes among adolescents living in participating communities surrounding Lira, Uganda.,Collect demographic information, baseline knowledge and beliefs about disease, and health-related behaviors from households in participating communities surrounding Lira, Uganda,To Asses a comprehensive Community health behaviours and practices in the Rural comminities in Lira District Northern Uganda. ,
 Uganda 2021-10-27 2024-10-27 Social Science and Humanities Non-Clinical Trial Non-degree Award
Peter Olds
ID: UNCST-2023-R006240
 The impact of the COVID-19 pandemic on NCD care in Mbarara, Uganda
REFNo: HS1535ES

1. Patients differentially sought medical care during the COVID-19 pandemic, resulting in different utilization of NCD care at health centers and a regional referral hospital.
2. We hope to understand both patient and provider perspectives on NCD care during COVID-19 pandemic, and discuss their outlook on more mobile versions of care.
 USA 2021-10-26 2024-10-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Urs KALBITZER
ID:
Aerial Imagery Data for the Construction of Primate Nutritional Landscapes
REFNo: NS303ES

To develop a methodological framework and create high-resolution models of the temporal and spatial distribution of nutrients for primates and other animals, so called ‘nutritional landscapes’
 Germany 2021-10-26 2024-10-26 Natural Sciences Non-Clinical Trial Non-degree Award
Kenia Martinez Raquel
ID:
PREVALENCE AND FACTORS ASSOCIATED WITH PRIMARY POSTPARTUM HEMORRHAGE AMONG WOMEN WITH PRE-ECLAMPSIA/ ECLAMPSIA DELIVERING AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1564ES

General Objective
To determine the prevalence and factors associated with primary postpartum hemorrhage among women with pre-eclampsia/eclampsia delivering at Mbarara Regional Referral Hospital

Specific Objectives
1. To determine the prevalence of primary postpartum hemorrhage in women with pre-eclampsia/ eclampsia at Mbarara Regional Referral Hospital.

2. To determine the factors associated with primary postpartum hemorrhage in women with pre-eclampsia/ eclampsia at Mbarara Regional Referral Hospital.

 Eswatini 2021-10-25 2024-10-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 A social media intervention to promote antiretroviral therapy adherence among adolescents and young adults living with HIV in Uganda
REFNo: HS1824ES

Determine the feasibility, acceptability, and preliminary effectiveness of the U-SMART intervention among AYAWH in Uganda.,Adapt the social media to improve ART outcomes (SMART) Connections platform to create Uganda-SMART (U-SMART), a novel WhatsApp-based social media intervention to improve antiretroviral therapy (ART) adherence among adolescents and young adults with HIV (AYAWH) in Uganda.,
 Uganda 2021-10-25 2024-10-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frank Mwiine Norbert
ID:
Epidemiological investigation of brucellosis in livestock in selected agro-pastoralist districts of Eastern Uganda
REFNo: A153ES

1. To determine the sero-prevalence of brucellosis in various livestock raised under the agro-pastoralist system in Eastern Uganda.
2. To establish the status and the factors behind the dynamics and perpetuation of livestock brucellosis in selected districts of Eastern Uganda.
3. To determine knowledge, attitudes and practices (KAPs) vital for brucellosis control among livestock farmers in the agro-pastoralist system in Eastern Uganda.
4. To isolate and molecularly characterize causative bacterial agents of brucellosis infecting livestock in Eastern Uganda.
5. To determine and raise awareness, biosecurity and biosafety on brucellosis and work with stakeholders to participatorily develop sustainable disease reduction protocols.

 Uganda 2021-10-25 2024-10-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Brenda Nakimuli Luswata
ID: UNCST-2021-R013228
 Refining the programme theory for realist inquiry on adolescent SRH accountability in disadvantaged urban areas: macro and meso-contextual drivers and social mechanisms. Case studies Uganda and Benin
REFNo: SS1032ES

(4) To develop guidance on accountability for adolescent girls living in urban slums and methodological guidance for realist evaluation of complex problems. (Work package 4),To develop an overarching programme theory (Work package 3),To test and refine the initial programme theory grounded in case studies conducted in two urban poor neighborhoods in Delhi and Mumbai, India ; Kampala, Uganda and Cotonou, Benin (Work package 2),To develop the initial programme theory on accountability towards adolescent girls living in urban slum, based on the MRT and existing imperical literature on accountability in sexual and reproductive health in an urban and rural health system (Van Belle, 2014, Van Belle & Mayhew, 2016; Van Belle et al. 2018),To contribute to a better understanding of the causal chain underlying accountability in sexual and reproductive health towards adolescents living in urban slums in LMIC. The,
 Uganda 2021-10-25 2024-10-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Erume
ID:
Antimicrobial resistance in zoonotic pathogens – a challenge for urban small holder livestock production system
REFNo: A156ES

1. To determine the burden of campylobacter infections in small holder, commercial broiler farms and food markets in and around Kampala, Uganda.
2. To determine management and risk factors which underlie the dynamics and perpetuation of in small holder, commercial broiler farms and food markets in and around Kampala, Uganda.
3. To establish the poultry farmers and traders’ knowledge, attitudes and practices related to AMR campylobacter strains and antibiotic usage at poultry farms.
4. To establish the AMR of campylobacters strains from the poultry phenotypically and molecularly including whole genome sequencing (WGS).

 Uganda 2021-10-25 2024-10-25 Agricultural Sciences Non-Clinical Trial Non-degree Award
Steven Odongo
ID: UNCST-2021-R013336
 DEVELOPMENT AND VALIDATION OF MULTIPLEXED LATERAL FLOW ASSAY FOR DETECTION AND DIFFERENTIATION OF SARS COV-2 FROM OTHER HUMAN CORONAVIRUSES
REFNo: HS1706ES

(1) Track levels of conservation of SARS CoV-2 structural proteins based on nucleotide sequences published in the Global Initiative on Sharing All Influenza Data (GISAID) database by sequencing laboratories in Uganda, (2) Identification and production of specific but conserved SARS-CoV-2 marker protein (s) capable of distinguishing SARS-CoV-2 from other hCoVs, (3) Develop a Nanobody (Nb) based multiplex LFA device targeting the marker proteins, and (4) Validate the performance characteristics of the LFA in a laboratory setting on archived sera.
 Uganda 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mark Jordans
ID: UNCST-2020-R014861
 Evaluating the effectiveness of Can’t Wait to Learn in formal education in Uganda
REFNo: SS1024ES

1)To assess the feasibility of the intervention and study (cRCT) methods, 2)To evaluate the effectiveness of CWTL in improving reading and numeracy outcomes of children in Primary 3 (P3), 3)To assess the value for money of CWTL and other factors for EdTech programme scale-up.
Netherlands 2021-10-22 2024-10-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Juliet Nattabi Kigongo
ID:
Vanishing Glaciers of the Rwenzori Mountains National Park (Uganda)
REFNo: NS291ES

Vanishing Glaciers project aims for the first
time to explore the streams of mountain
biogeochemistry, and the living
microorganisms of these remote
ecosystems, now strongly impacted by
climate change.
The project’s main goals are:
• To establish the census of microbial
life of the world’s glacier-fed
streams.
• To predict the future changes of the
glacier-fed streams biogeochemistry
as the world’s glaciers recede

1. Study the microbial life from glacier-fed streams
2.Study the biogeochemistry of glacier-fed streams
3.Study the environment of glacier-fed streams, including glaciological parameters
 Uganda 2021-10-22 2024-10-22 Natural Sciences Non-Clinical Trial Non-degree Award
Andrew Katumba
ID:
Performance of a novel, rapid AI-driven screening tool for improved COVID-19 patient care and management in Uganda
REFNo: SIR74ES

General Objective
To develop and deploy AI-driven screening tools for improved care and management of COVID-19 patients. This will be achieved through the following specific objectives:
Specific Objectives
1. To collect, curate and label Lung Ultrasound (LUS) images from COVID-19 patients and patients with related pulmonary pathologies such as non-COVID-19 derived pneumonia, yielding a generalizable and representative image/video dataset.
2. To develop robust image-driven machine learning (ML) models for detection and screening of COVID-19 using the data from objective 1.
3. To build mobile and web-based applications that integrate the ML models, for online (real-time) and offline COVID-19 screening.
4. To pilot the developed applications and evaluate their clinical efficacy in COVID-19 screening.

Uganda 2021-10-22 2024-10-22 Engineering and Technology Non-Clinical Trial Non-degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
 Identification and characterization of Diabetes in low-resource Populations
REFNo: HS1791ES

The secondary study objectives are:
1. To establish a base-line cohort of well-characterised people with diabetes to understand disease progression of the different phenotypes, including uptake and response to treatment.
2. To identify and recruit a cohort of non-diabetic volunteers (including prediabetes i.e., at high risk of developing diabetes) for longitudinal follow-up.
i. To identify a cohort of non-diabetic people in order to measure the incidence of disease in the future estimate incidence of diabetes.
ii. To assess the burden and rates of progression of vascular complications associated with the different phenotypes of dysglycaemia.
Malawi 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frederick Mubiru Edward
ID:
Market Research on User Perspectives for a 4-month Depot Medroxyprogesterone Acetate Subcutaneous (DMPA-SC) Product
REFNo: HS1792ES

1. To solicit input from potential and current contraceptive injectable users, as well as males/partners, on acceptability and implications for having multiple injectable products of different durations in the market, with an emphasis on a 4-month DMPA-SC product as well as a potential 6-month injectable
2. To co-create marketing strategies/messages with current and potential users for the introduction and differentiation of new injectable products

 Uganda 2021-10-22 2024-10-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Josef Bryja
ID:
Evolutionary diversity of small mammals in isolated mountains in north-eastern Uganda - stepping stones for colonization of the Albertine Rift and Kenyan Highlands from Ethiopia?
REFNo: NS301ES

Overall goal: To analyse genetic diversity of small mammals and their pathogens to test alternative hypotheses of colonization of Eastern Afromontane Biodiversity Hotspot (EAMBH)
Objective: Description of biodiversity patterns in EAMBH using integrative approach

Output 1: List of small mammals of isolated sky islands of north-eastern Uganda
Activity 1: Field sampling, species identification (using integrative approach)

Output 2: Phylogeographic scenarios for the colonization of EAMBH, identification of "refugia within refugia", biogeographical regionalization
Activity 2: Combination of obtained (genetic) data with other datasets from Ethiopia, Kenya, Tanzania, etc. Testing of phylogeographic hypotheses.

 Czech Republic 2021-10-22 2024-10-22 Natural Sciences Non-Clinical Trial Non-degree Award
Eddy Walakira Joshua
ID: UNCST-2022-R009077
 Strengthening the Effectiveness of National Children’s Care Systems: A Political Analysis of Uganda
REFNo: SS1064ES

This study will examine the effectiveness of the National Children’s Care System in Uganda focusing on the political, bureaucratic and economic forces as well as the strategies that augment the effectiveness of this system.

The study aims to use the collected data to develop an adaptable framework to achieve effective national care systems for children in Low-Income Countries (LICs).

In specific terms, the research will:
1. Examine the political, bureaucratic and economic forces shaping the effectiveness of Uganda’s national children’s care systems

2. Delineate the strategies to improve the capacity of these systems to protect children

3. Develop an adaptable framework for Uganda to analyze factors shaping children’s care systems in LICs?
 Uganda 2021-10-22 2024-10-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Gorretti Nassali
ID:
Trends of Breast Cancer among patients younger than 40 years at St. Francis Hospital Nsambya: A cross section descriptive study
REFNo: HS1758ES

This study aims to describe prevalence by age, stage at diagnosis, cancer type and grade, and hormone receptor status, among women younger than 40 years at St. Francis Hospital Nsambya between 2010 and 2020.
 Uganda 2021-10-21 2024-10-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Anna Ritah  Namuganga
ID:
Mycobacterium tuberculosis associated immune activation and exhaustion profiles for prediction of active pulmonary tuberculosis
REFNo: HS1201ES

Main Objectives
Determine the differential expression of immune activation and exhaustion markers to predict active TB disease among presumptive TB cases.
Primary Specific Objectives
i. To determine the levels of soluble markers of immune activation and exhaustion in serum of active PTB cases, LTBI and those with ORDs and response to treatment.
ii. To determine levels of immune activation and exhaustion associated cytokines/chemokines in serum among active PTB, LTBI and ORDs and response to treatment.
iii. Perform a phenotypic profiling of expression of markers immune activation and exhaustion in PBMCs and determine their association with active PTB, LTBI states or other respiratory diseases (ORDs).
iv. To determine the activation and exhaustion genes expression profiles in QFT Gold plus cell pellets and compare levels in active PTB cases and LTBI.

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Degree Award
Andrew Okwi Livex
ID: UNCST-2021-R013180
 Unlocking the potential of thiocyanate in cassava root for management of painful crisis in sickle cell disease patients in Uganda
REFNo: HS1486ES

1. To determine the frequency of cassava consumption in the districts of Uganda with high prevalence of sickle cell disease
2. To assess the frequency of painful crisis among SCD patients in these districts.
3. To determine the levels of thiocyanate in patients with SCD in these districts
4. To determine the optimum concentration of thiocyanate that causes antisickling (in vitro studies)

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Khamisi Musanje
ID: UNCST-2021-R012863
 Acceptability, Feasibility and Effectiveness of a Mindfulness based Intervention to Promote Adherence to Antiretroviral Therapy among Adolescents in Kampala.
REFNo: HS1656ES

1. To adapt and explore acceptability of ACT-DNA-v among users (ALWHA) and providers (HCPs).
2. To measure feasibility of the adapted ACT-DNA-v for use with ALWHA.
3. To examine the impact of ACT-DNA-v on reducing proximal psychosocial barriers to medication adherence (depression, anxiety and stigma) among ALWHA.
4. To measure effectiveness of a mindfulness based intervention (ACT-DNA-v) on self-reported adherence among ALWHA in Kampala, and ascertain its impact on viral load reduction via analysis of data from medical records

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Damalie Nalwanga
ID: UNCST-2021-R013217
 SEVERE PNEUMONIA IN CHILDREN: THE ABILITY OF BODY COMPOSITION TO PREDICT SURVIVAL, AND THE EFFECT OF NUTRITIONAL SUPPLEMENTATION ON OUTCOMES
REFNo: HS1719ES

4. To determine the effect of a nutritional intervention (RUTF) on clinical outcomes (post discharge mortality, re-admission, and occurrence of severe acute malnutrition) of children hospitalized for severe pneumonia.,3. To determine the effect of a nutritional intervention (RUTF) on fat and muscle mass in children hospitalised for severe pneumonia.,2. To compare the ability of various muscle and fat mass indices to predict survival in children hospitalised for severe pneumonia.,1. To describe the role of nutritional status on outcomes following hospitalization for severe pneumonia among children.,To describe the relationship between muscle and fat mass and survival, and determine the role of nutritional supplementation on fat and muscle mass, and on treatment outcomes of children hospitalized for severe pneumonia,
 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 A Public Health Approach to Cervical Cancer Prevention in Uganda
REFNo: HS1727ES

Aim 1. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based cervical cancer screening program.

Aim 2. To evaluate the uptake of, acceptability regarding and factors explaining non-participation in a community-based HPV vaccination program.

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan Adakun
ID:
Comparing adherence to MDR-TB treatment among patients on self-administered therapy and those on Directly Observed Therapy: Non Inferiority Randomized Controlled Trial
REFNo: HS1796ES

Primary Objectives
1. To determine if adherence to MDR-TB treatment among patients on self-administered therapy (measured by Medication Events Monitoring System (MEMS) technology) is non-inferior to that among patients on Directly Observed Therapy (DOT)
Secondary objectives

1. To determine the correlation between serum MDR-TB drug concentrations and adherence as measured by MEMS technology


2. To compare treatment outcomes between MDR-TB patients on self-administered therapy and DOT

 Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Winfred Naamara
ID:
Understanding social support for family caregivers of patients with schizophrenia in greater Kampala metropolitan area, Uganda
REFNo: SS1038ES

The overall objective of this study is to examine how family caregivers of patients with schizophrenia generate and experience social support in greater Kampala metropolitan area.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Sandra Lamwaka
ID:
TOWARDS A NEWS INDUSTRY FRAMEWORK FOR TACKLING THE VICE OF BROWN ENVELOPE JOURNALISM: PERCEPTIONS OF JOURNALISTS AND PUBLIC RELATIONS PRACTITIONERS IN UGANDA
REFNo: SS1014ES

1. To examine journalists and PR practitioners’ perception of the brown envelope. 2. To identify the various forms that BEJ takes in Uganda. 3. To find out journalists and PR practitioners' perceptions on why BEJ is prevalent and enduring in Uganda. 4. To find out journalists and PR practitioner's perspectives on the policies that the media industry can employ to address the practice of BEJ in Uganda.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
JANISCH Judith Judith
ID:
Ecological influences on Locomotor Performance in Free-Ranging Primates: a phylogenetic investigation
REFNo: NS299ES

- to investigate the evolution of arboreal locomotion in primates and discern which aspects of the arboreal environment most directly influence their locomotor performance.
- to describe kinematics of different primate species (Cercopithecus mitis, Cercopithecus ascanius, Cercopithecus lhoesti, Chlorocebus aethiops,
Lophocebus albigena, Papio anubis, Colobus guereza and Piliocolobus badius) in
their natural habitat and analyze the variation in a phylogenetic context.

 Austria 2021-10-19 2024-10-19 Natural Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
 Exploration of the Virologic Characteristics of Recently Transmitted HIV-1 Viruses in Uganda and Kenya
REFNo: HS1635ES

1. To identify key unique molecular features of T/F virus strains and characterize them
2. To relate these unique genetic features to viral protein structures and in vitro virus phenotypes.
3. To determine the difference between HIV-1 co-receptor usage of the T/F virus variants and NT virus strains.
4. To determine particle infectivity of T/F virus strains in comparison to that of the NT virus strains.
5. To compare the resistance of T/F virus strains to the antiviral effects of type I interferons to that of the NT strains
6. To determine the sensitivity of T/F virus strains to broadly neutralizing antibodies in comparison to the non-transmitted virus strains.
 Uganda 2021-10-15 2024-10-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noah Kalengo
ID:
LIVED EXPERIENCES OF UNCIRCUMCISED POKOT WOMEN IN AMUDAT DISTRICT
REFNo: SS1046ES

To explore the characteristics of uncircumcised Pokot women in Amudat District.

To explore the psychosocial experiences of uncircumcised Pokot women in Amudat District.

To analyze the protective factors/coping resources among the uncircumcised Pokot women that enable them to survive despite their experiences.

 Uganda 2021-10-15 2024-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
 Feasibility and acceptability of integrating PrEP and safer conception messaging into assisted partner notification
REFNo: HS1625ES

To examine the feasibility and acceptability of integrating gain-framed vs. loss-framed messages on PrEP and safer conception into the assisted partner notification (APN) program in Uganda
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Smart Triage + QI: A digital triaging platform to improve quality of care for critically ill children
REFNo: HS1745ES

To identify and examine opportunities for ongoing improvement to strengthen the health system. ,To enable healthcare workers to recognize the most urgent children more rapidly and allocate existing resources more efficiently,To implement Smart Triage + QI to improve the quality of care at three UCMB health care facilities and Gulu Regional Referral Hospital (a government facility). ,
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
 Uganda Paediatric and Adolescent HIV Cohort on Antiretroviral Therapy: Study Protocol (UP-ART)
REFNo: HS1699ES

The objectives of this study are to:
1) Describe the characteristics of children and adolescents living with HIV receiving paediatric care in the participating centres and coverage of ART
2) Describe the uptake of new antiretroviral drugs such as DTG across age groups and regions
3) Assess the effectiveness and safety of new antiretroviral drugs such as DTG, including viral suppression, incidence of adverse events, serious adverse events and discontinuation of drug
4) Assess broader clinical outcomes including retention in care, mortality, disease progression, immune response, viral suppression, overall and by age and treatment regimen/treatment history
5) Assess (i) the prevalence of HIV drug resistance among children/adolescents start of treatment and the impact on treatment response, and (ii) among those who experiencing virological failure on DTG to describe the risk of accumulation of drug resistance (see sub-study Section 4).

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Integration of phone-based data capture tool to support real-time reporting and quality assurance of SARS-CoV-2 Ag RDT in Uganda
REFNo: HS1723ES

1. To pilot the integration of phone-based data collection tool and real-time reporting via a dashboard
2. To monitor quality and post-market surveillance of the Ag RDT in Uganda
3. To demonstrate the use of remnant Ag RDT samples in the routine surveillance of SARS –CoV-2 variants in Uganda
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Miriam Nakalembe
ID: UNCST-2021-R014040
 Use of mobile Text Messaging Service information for mothers in situations of limited access to physical antenatal and postnatal services during the COVID-19 Pandemic
REFNo: HS1732ES

1. To elicit requirements for incorporating maternal and child health educative messages into the developed mobile-based transport technology for mothers.
2. To incorporate maternal and child health educative messages into the developed mobile-based transport technology for mothers.
3. To evaluate the usefulness of the information to the mothers through the mobile Text Messaging Service.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ivan Segawa
ID: UNCST-2021-R012795
 Nurse-led PrEP Delivery for Young Women Attending Family Planning Clinics in Uganda
REFNo: HS1740ES

Aim 1: To evaluate the feasibility and acceptability of nurse-led PrEP delivery to adolescent girls and young women attending a family planning clinic in Uganda.

Aim 2: To assess PrEP persistence among adolescent girls and young women receiving nurse-delivered PrEP at a family planning clinic.

Aim 3: To compare the characteristics of adolescent girls and young women who accept with those who decline PrEP and those who persist with those who discontinue PrEP at a family planning clinic in Uganda.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nixon Niyonzima
ID: UNCST-2020-R014577
 Utility of a Liquid Blood Biopsy for Non-invasive Lung Cancer Diagnosis and Biomarker Testing at Uganda Cancer Institute.
REFNo: HS1743ES

1. To compare ctDNA sequencing to standard histopathologic diagnoses of lung cancer in patients with advanced stage lung cancer at the Uganda Cancer Institute (UCI).

2. To describe the tumor-specific molecular alterations present in lung cancer specimens and ctDNA in advanced stage lung cancer patients at UCI.
 Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ouma Simple
ID: UNCST-2021-R012820
 Childhood victimization and mental disorders among adolescents of sex-working and non-sex working mothers in post-conflict Gulu city in Northern Uganda - a cross-sectional study
REFNo: HS1769ES

The main goal of this study is to provide the evidence needed by the health care programmers and policymakers to inform appropriate policies and practices on prevention, screening, and management of victimizations among adolescents in Uganda. Specifically, the following are the study objectives:
1. To determine the prevalence of childhood victimization among adolescents.
2. To examine the relationship between sociodemographic characteristics and general health and childhood victimization among adolescents.
3. To examine the relationship between maternal sex work status and childhood victimization.
4. To examine the relationship between maternal major depression and childhood victimization among adolescents.
5. To determine the prevalence of selected childhood mental disorders among adolescents.
6. To examine the relationship between exposure to childhood victimization and childhood mental disorders in post-conflict Gulu City.

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Degree Award
Achilles Katamba
ID: UNCST-2019-R000540
 Interrupting HIV and TB Stigma in the Household during TB Contact Investigation in Uganda
REFNo: HS1788ES

This project aims to evaluate the effects of a complex intervention on household HIV stigma and uptake of HIV testing among household members undergoing TB contact investigation.
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
 Evaluating the impact of the COVID-19 pandemic restrictions on HIV care in Kampala, Uganda: a propensity-score matched and difference-in-differences analysis
REFNo: HS1709ES

Primary objective: To evaluate the impact of the COVID-19 pandemic restrictions on linkage to care, time to linkage, timely ART initiation, retention in care, viral load suppression, and mortality among people living with Human Immunodeficiency Virus (PLHIV) in the Kampala Capital City Authority (KCCA) health facilities in central Uganda

Secondary objective: To document and synthesize measures for continuity of service delivery for PLHIV during the COVID-19 pandemic
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Betty  Nambuusi Bukenya
ID:
Youth Wellbeing Champions: Piloting community-based, youth peer-led mental health and wellbeing support for young people in Uganda
REFNo: SS956ES

Study goal: To generate evidence around the effectiveness of a pilot community-based and responsive wellbeing / mental health intervention led by young people with lived experience of care and supported by social work practice/practitioners in Uganda. Specific objectives 1. Assess the level of knowledge and understanding of a trauma-informed approach to addressing mental health needs among social workers based on the Kirk Patrick pre-post questionnaire. 2. Assess the prevalence of clinical mental health, well-being, self-esteem/ self-worth, and depression symptoms among children and youth based on the WHO-5 / PHQ-9 and Rotter’s Locus of Control. 3. Examine the level of knowledge of mental health literacy, resilience, psychosocial support, and wellbeing practice among care leavers based on Kirk Patrick's pre-and post-assessments questionnaire.
Uganda 2021-10-12 2024-10-12 Social Science and Humanities Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Youth Health SMS: Using mobile technology to prevent HIV and related Youth Health problems: Sexual health, Mental health, and Substance use in southwest Uganda
REFNo: SS969ES

This study will result in the development of one of the first mobile phone-based interventions for Adolescents and Young Adults (AYA) in East Africa that begins to address the co-morbid HIV risk factors of sexual health, mental health, and alcohol use. AYA is a developmental period associated with the increased importance of peers, increased technology use, increased mobility, initiation of sex, emergence of mental health disorders (if at risk), and initiation of alcohol use. Consequently, AYA is a critical time for preventive interventions. Poor mental health and alcohol abuse are associated with increased risk for HIV infection. Thus, the proposed research will attempt to address these areas concurrently.

The proposed research will evaluate if adapting and updating the existing free and nationally available text message and interactive voice recognition (IVR) service included in *161 that was initially developed by FHI 360. Our work will test and tailor messages for AYA to disseminate pre-exposure prophylaxis (PrEP) information and pilot specific mental health and hazardous alcohol use screens. Symptomatic AYA will be referred to behavioral health counselors for further assessment and treatment as needed. AYA today rely heavily on mobile phones for information and services, thus we believe the proposed intervention could be applied and adapted across the region, and potentially in other under-resourced settings.

We will conduct formative research to evaluate and adapt an existing text-message and interactive voice recognition (IVR) platform. We will then pilot the new menus and examine if using this platform promotes HIV prevention (pre-exposure prophylaxis (PrEP), HIV testing, safer sexual behaviors) and increases mental health and alcohol use screening and linkage to counselors as needed for adolescents and young adults (AYA) in a rural Ugandan region with high HIV seroprevalence and limited resources.

2. State the study objective(s) and research question(s)
Aim 1: To adapt an evidence-based mobile phone-delivered sexual health program, to include PrEP information and deliver mental health and alcohol use assessments with the goal of increasing screening and referral, as well as linkage to counselors for AYA at HIV risk.

Aim 2: Evaluate through a pilot RCT (N=126 AYA, 15-19 years) intervention (a) acceptability and feasibility, and (b) impact on uptake of HIV prevention strategies, as well as screening and linkage to mental health and alcohol use school-based counselors.

 Uganda 2021-10-12 2024-10-12 Social Science and Humanities Clinical Trial Non-degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 Mortality Surveillance Activity Protocol All-cause Mortality Surveillance in Bunyangabu, Kabarole and Kyenjojo districts, Uganda
REFNo: HS1755ES

the objective of establishing a mortality surveillance system is to enumerate and document all-cause mortality in the 3 districts of Bunyangabu, Kabarole, and Kyenjojo in Uganda. Specifically this will; a) determine HIV/AIDS related and proportionate mortality rate in the three districts, b) determine maternal and neonatal mortality rates in the three districts c) identify causes of death among HIV patients and causes of pregnancy-related deaths in the three districts and d) document the implementation process of mortality surveillance in order to inform future scale up.
 Uganda 2021-10-12 2024-10-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waruiru Kolff Kayla Tinie
ID: UNCST-2021-R012291
 Turn-taking interactions in Eastern male Chimpanzees (Pan troglodytes schweinfurthii)
REFNo: NS295ES

Understanding the turn-taking systems of chimpanzees and how this relates to human language and it's origins. Hence, whether the turn-taking systems of chimpanzees are influenced by interpersonal contexts (social bonds & dominance rank).
 Netherlands 2021-10-12 2024-10-12 Natural Sciences Non-Clinical Trial Degree Award
ALEX NDYABAKIRA
ID:
Assessing use of SolarSack for treatment of safe drinking water in Uganda
REFNo: HS1680ES

1. To determine the willingness to buy and acceptability of SolarSack water treatment device
2. To determine the most appropriate cost per unit for SolarSack for rural, peri-urban and urban settings
3. To explore user preferences for the SolarSack device
4. To determine the effect of SolarSack use on prevalence of waterborne diseases

 Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phyllis Kisa
ID: UNCST-2023-R007952
 SURGICAL NEONATES IN A LOW-RESOURCE SETTING: AN AUDIT OF NUTRITION AND OUTCOME
REFNo: HS1736ES

To audit our current the nutritional regime among newborns with gastro-intestinal anomalies admitted to the Paediatric Surgical Unit at Mulago National Referral Hospital(MNRH).
Uganda 2021-10-11 2024-10-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tukwasiibwe Moses
ID:
Impact of forced displacement on labour markets in Uganda
REFNo: SS1039ES

Objective 1) Provide strong empirical evidence of the direct and indirect impacts. Against the backcloth of a comprehensive literature survey, and investigating non-camp urban refugee populations in Kampala and as well as camp based refugees in Nakivale refugee settlement in Uganda.

Objective 2) Identify the mechanism(s?) through which impacts occur. Analyzing the empirical evidence we will: i) explore direct and indirect (partial equilibrium) impacts and outcomes on the dynamics of labor market and business behavior, assessing impact-attribution and correlating variables such as labor supply and wages, capital investment/ labor trade-offs and demand side factors, productivity and skills, national and international investment patterns; ii) assess the role of political economy, regulatory and policy frameworks; iii) generate qualitative analysis of household and individual livelihood/life course experiences in relation to labor market outcomes, iv) generate local, national and comparative findings.

Objective 3) Support the development of evidence-based, effective, and context-specific jobs policy advice. The analytical outputs will provide a robust evidence base for jobs policy advice envisaged at different levels (local, national, and international), and for different stakeholders (e.g. municipal and national governments, donors, intergovernmental and non-governmental organizations, private sector investors, entrepreneurs and SME sector, and displaced and host populations). Policy advice will include, inter alia: finance and investment strategies, regulatory framework e.g. rights to work/rights at work and employer conditions for decent work), spatial planning, training and skills, role of investment incentives, socio-economic policies for displaced and host populations vis à vis labor markets.

Objective 4) Generate new data that will be in the public domain for use in further research. The proposed study will generate new statistical (survey) data sets for three of the four case countries: Colombia, Ethiopia and Uganda. In Jordan, the study team is already in possession of sufficient data through previous surveys conducted by Fafo and partners. When designing the new surveys, special attention will be given to establish robust baselines that can be applied in future impact analyses. Responding to this objective and the general TOR requirements, we shall place all the data generated in the proposed project in the public domain.

Uganda 2021-10-11 2024-10-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
PETER OMASWA
ID:
Relevance and Factors Affecting Exchange of Plant Material and Data to Conservation
REFNo: NS156ES

General Objective
To assess the importance of plant material and data exchange between African and European Institutions for conservation.

Specific Objectives
1. To review the extent to which plant material and data are exchanged between African and European institutions.

2. To evaluate the opportunities and constraints to plant material and plant data exchange between African and European Botanical Institutions.

3. To evaluate the proportion of exchanged plant material and data translated into conservation applications.


 Uganda 2021-10-08 2024-10-08 Natural Sciences Degree Award
Carolyn Nakisige
ID:
Preventing cervical cancer in HIV-infected Kenyan and Ugandan women
REFNo: HS1372ES

1. To evaluate HR-HPV DNA testing of self-collected vaginal swabs combined with VIA in screening for cervical cancer in HIV-infected women.
2. Determine if aflatoxin is a risk factor for cervical cancer among HIV-infected Kenyan and Ugandan women.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alice  Emasu
ID: UNCST-2021-R013920
 EXPERIENCES OF LIVING WITH OBSTETRIC FISTULA AMIDST COVID -19 PANDEMIC IN EAST AND CENTRAL UGANDA: Qualitative study.
REFNo: HS1464ES

General Objective
To document the experiences of living with fistula amidst the COVID-19 pandemic among women who developed OF during corona virus pandemic, those who had fistula and had started seeking for care, those who were repaired and were at the stage of reintegration and those declared as incurable between 15-49 years of age from Eastern and Central Uganda

Specific objectives

1) To document participant’s awareness about COVID 19 Pandemic

2) To explore the perceptions of women living with OF amidst COVID 19 Pandemic

3) To explore the effect of COVID -19 on the livelihood of women with OF.

4) To explore experience in accessing fistula services among women reintegrating and screened for surgeries during the COVID-19 pandemic.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Scovia  Mbalinda Nalugo
ID: UNCST-2020-R014259
 Aging with HIV: Experiences and challenges of older adults 50 years and above living with HIV
REFNo: HS1759ES

3. To explore determine the challenges faced by older adults 50 years and above aging with HIV.,2. To describe the experiences of older adults 50 years and above aging with HIV.,The goal of this study is to explore the experiences, perceptions, and challenges of older adults 50 years and above aging with HIV.,
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Juma Kalyegira
ID:
The Role of Basic Psychological Needs Satisfaction for the Psychological Wellbeing and Social-Cultural integration of Refugees in Rhino Camp Refugee Settlement, Uganda
REFNo: SS905ES

• To estimate the relationship between the three psychological basic needs satisfaction (Autonomy, relatedness and competence) to the psychological wellbeing of refugees.
• To determine whether the basic psychological needs satisfaction influences refugee integration.
• To find out what factors influence the need satisfaction/frustration for refugees and how?
• To estimate whether physical and psychological need satisfaction interact in an “unprepared to benefit” or “buffering against adversity” direction?

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
John Byabagambi Bekiita
ID:
Ability and willingness to pay for voluntary medical male circumcision in Uganda: A mixed-methods study
REFNo: HS1523ES

1. To identify the factors that determine the ability to pay for VMMC in Uganda.
2. To determine the factors associated with willingness to pay for VMMC services in Uganda.
3. To find out the reasons that inform the choice of either the willingness to pay or not to pay for VMMC services in Uganda.

 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
 Pandmic-related disruptions in HIV care among adolescents and young adults with HIV (AYAWHIV) and the potential for mHealth interventions.
REFNo: HS1686ES

To examine the effects of the COVID-19 restrictions on HIV treatment of AYALWHIV and assess the potential of mHealth intervention in bridging these disruptions.
 Uganda 2021-10-08 2024-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Nalugoda
ID: UNCST-2021-R013343
 Transactional sex and HIV among men in Rakai, Uganda
REFNo: SS984ES

The overall goal of this research is to understand the characteristics of men who engage in transactional sex and the causal pathways that lead from transactional sex to incident HIV in Rakai, Uganda.
• Aim 1. To measure perceptions, content validity, and response processes of transactional sex measures in the Rakai Community Cohort Study
• Aim 2. To examine men’s experiences in transactional sex relationships and factors that may heighten risk for HIV

Uganda 2021-10-08 2024-10-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dorothy Stamps Sarah
ID: UNCST-2019-R001036
 Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS294ES

Investigating the physics of strain accommodation in the magma-poor Albertine- Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
 USA 2021-10-08 2024-10-08 Natural Sciences Non-Clinical Trial Non-degree Award
Marsiale Kamugisha
ID:
'Analysing the Impact of Transformative Governance and Agroforestry on Household Food Security in Southwestern Uganda'
REFNo: A130ES

1)To assess contributory factors responsible for determining household transition to food security.
2)To evaluate the household governance system that enhances agroforestry-based food security.
3)To assess households’ potential benefits of agroforestry beyond food security.

Uganda 2021-10-06 2024-10-06 Agricultural Sciences Non-Clinical Trial Degree Award
Nadine Schubert
ID:
Genetically-based social communication in an inbred group-living wild mammal
REFNo: NS273ES

The aim is to investigate the role of immune genes of the major histocompatibility complex (MHC) in affecting odour cues used for social communication in banded mongooses. Furthermore, we want to investigate the link between MHC composition of an individual and fitness parameters as well as the impact of the MHC on microbiota communities. Last, it is crucial to test the ability of banded mongooses to discriminate MHC-based differences in odour cues in a natural setting.
 Germany 2021-10-05 2024-10-05 Natural Sciences Non-Clinical Trial Degree Award
Christine  Wiltshire Sekaggya
ID: UNCST-2019-R000578
 Clinical Predictors of 3-Months Isoniazid Rifapentine (3HP)- Related Adverse Drug Reactions (ADR) During Tuberculosis Preventive Therapy (PAnDoRA-3HP study)
REFNo: HS1582ES

Primary Objectives
1.To describe the safety profile of 3HP among people receiving tuberculosis preventive therapy.
2.To describe the effect of adverse drug reactions on tuberculosis preventive therapy completion rates
Secondary Objective
1.To describe the pharmacokinetic and pharmacogenomic determinants of ADRs among people receiving tuberculosis preventive therapy in Uganda
2.To determine the efficacy of 3HP when used for tuberculosis preventive therapy.

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joseph Lutaakome
ID: UNCST-2020-R008323
 An International Multicenter, Randomized, Double-Blind, PlaceboControlled Trial of the Safety and Efficacy of Anti-Coronavirus Hyperimmune Intravenous Immunoglobulin for the Treatment of Adult Outpatients in Early Stages of COVID-19
REFNo: HS1715ES

Primary Objective
Primary objective: Among outpatients with recently diagnosed SARS-CoV-2 infection to compare the safety and efficacy of a single infusion of hIVIG (pooled for the 2 hIVIG

products) versus placebo, each given with SOC, on clinical status after seven days. Two hypotheses will be tested to address this primary objective, which compares the primary endpoint among two study populations: 1) participants where neutralizing MAb was not specified as part of SOC treatment (stratum 1, see Section 6.1 Overall Study Design); and 2) all randomized participants (stratum 1 and stratum 2 combined). hIVIG will be considered superior to placebo if either of the two hypotheses are rejected.
Secondary Objectives and Endpoints
Secondary objectives, including subgroup analyses and safety outcomes, will be addressed for all randomized participants and for those in stratum 1 and 2 separately.
Secondary Endpoints
The clinical status as classified on the ordinal outcome scale will be assessed with a number of additional analyses comparing hIVIG (pooled for the 2 hIVIG products) with placebo, among the overall study population as well as for the key subgroup of those not receiving anti-SARS-CoV-2 monoclonal antibodies as part of SOC (stratum 1), including:
1. All-cause hospitalization or death through 28 days.
2. All-cause mortality through 28 days.
3. Significant disease progression through 28 days, using a time to event analysis with outcome defined by fulfilling criteria for category 4 or 5 on the ordinal scale.
4. Distribution of ordinal scale outcome at Day 4, 14, and 28.
5. The proportion of participants with any disease progression at Day 7, using a sliding dichotomous scale progression defined by a categorization on the ordinal scale that is worse than the status at entry

 Uganda 2021-10-04 2024-10-04 Medical and Health Sciences Clinical Trial Non-degree Award
Joyce  Nankumbi
ID:
The status of OFSP production, utilization and the nutritional status and welfare of sweet potato growing households in northern and eastern Uganda
REFNo: A152ES

1. To characterise the consumption of vitamin A rich foods among households in the selected northern and eastern districts of Uganda 2. What is the food security status in the households in the selected northern and eastern districts in Uganda? 3. To document the production and consumption of orange-fleshed sweet potato among households in the selected northern and eastern districts in Uganda? 4. To identify infant feeding practices of women in the selected districts of northern and eastern regions in Uganda? 5. To identify water, hygiene and sanitation practices of households in the selected northern and eastern districts in Uganda 6. To establish the knowledge, attitudes and perception on the consumption of beta carotene-rich orange-fleshed sweet potatoes/ vitamin A-rich foods among households in the northern and eastern regions in Uganda,To determine status of orange-fleshed sweet potato production, utilization and the nutritional status and welfare of sweet potato growing households. in northern and eastern Uganda ,
 Uganda 2021-10-01 2024-10-01 Agricultural Sciences Non-Clinical Trial Non-degree Award
Arthur Nuwagaba
ID:
TOP MANAGEMENT TEAM CHARACTERISTICS AND PERFORMANCE OF UGANDAN STATE AGENCIES
REFNo: SS999ES

iv. Establish the joint effect of top management team characteristics, strategy implementation and external environment on the performance of Ugandan state agencies.,iii. Determine the moderating effect of the external environment on the relationship between top management team characteristics and the performance of Ugandan state agencies.,ii. Establish the mediating effect of strategy implementation on the relationship between top management team characteristics and performance of Ugandan state agencies.,i. Determine the influence of top management team characteristics on the performance of Ugandan state agencies.,The main objective of the study is to determine the influence of strategy implementation and external environment on the relationship between the TMT characteristics and the performance of state agencies in Uganda.,
 Uganda 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Degree Award
Wang Vibeke
ID:
Supporting Parenting Care Corners in Markets to Reduce Unpaid Care Work for the Vulnerable Business Women in Uganda
REFNo: SS944ES

1. To deepen the evidence base on whether and how reducing women’s unpaid childcare burden increases their productivity and income.
2. To examine the factors that impede access to parenting care facilities among vulnerable women engaged in business markets in Uganda and how these could be mitigated.
3. Evaluate the effects of parenting care facilities, financial subsidy and parents’ training on the productivity of mothers and profitability of their businesses.
4. To inform government action through tested and proven models for scaling up parenting care corners to both structured and unstructured markets
5. To provide proof of concept on how governments can introduce affordable, effective, and sustainable childcare models that work for vulnerable mothers who work in informal markets in Uganda.

Norway 2021-10-01 2024-10-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aida Cuni Sanchez
ID:
Monitoring forest dynamics in Bwindi National Park
REFNo: NS282ES

• Does tree growth change with increasing altitude?
• How do taxonomic, forest structural and environmental attributes affect tree growth?
• How do carbon stocks change over time at different altitudes?

 Spain 2021-10-01 2024-10-01 Natural Sciences Non-Clinical Trial Non-degree Award
Radhika Sundararajan Lu
ID:
A pilot study of adherence support delivered by informal health providers to improve entry to and retention in HIV care in rural Uganda
REFNo: HS1747ES

: Pilot test the adapted intervention to evaluate implementation and impact on linkage/retention in HIV and ART adherence among individual PLWH,Adapt an evidence-based layperson adherence support curriculum for delivery by TH.,
 USA 2021-10-01 2024-10-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Evaluation of Clinical Chemistries from Biospecimens Collected with a Painless Capillary Blood Collection TASSO SST Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1751ES

We plan to compare capillary chemistry values collected via the painless Tasso collection device to standard serum chemistry values collected via venipuncture at a single study visit (Day 28 of the main study(HS 2292)) for each consenting participant. We plan to evaluate the correlation between chemistry values from capillary versus venous blood collection and identify any scenarios where the values diverge such as for high or low values or for specific analytes collected in a remote field location. We plan to review the failure rate and causes for failure for the Tasso device
 Uganda 2021-10-01 2024-10-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Ntaro
ID: UNCST-2020-R014133
 Effect of student community engagement on sanitation behavior: a case of Community Led Total Sanitation in Kabale District
REFNo: HS1135ES

To evaluate the effect of students community engagement on household level ODF status in Kabale District, Uganda so as to demonstrate the contribution of students in improving CLTS implementation and outcomes
 Uganda 2021-09-29 2024-09-29 Medical and Health Sciences Degree Award
Mohammed Lamorde
ID: UNCST-2019-R001293
 Infant extended safety follow-up study – an observational study of brain imaging and child development in infants (DolPHIN-2 PLUS)
REFNo: HS1639ES

1. To determine if there are developmental differences following exposure to DTG or EFV. 2. To examine brain structure and microstructure of HEU children. 3. To determine developmental outcomes. 4. To validate the Hyperfine, low-field MRI system 5. To explore the impact of environmental factors such as antenatal iron-deficient anaemia on brain development in a high-risk birth cohort
Nigeria 2021-09-29 2024-09-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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