ERIC WOBUDEYA
ID: UNCST-2019-R001047
|
A randomised trial of 6 months intensified anti-tuberculosis and 2 months anti-inflammatory treatment for HIV-infected and HIV-uninfected African and Asian children with tuberculous meningitis
REFNo: HS593ES
Main objectives of the SURE trial
a) To determine whether the standard 12 month ATT regimen for treating paediatric TBM can be reduced to 6 months with similar efficacy and safety, with an intensified regimen of anti-TB drugs in children aged under 15 years with TBM AND b) To determine whether adjunctive aspirin for the first 60 days of treatment reduces TBM-related neuro-disability with minimal or no toxicity in children with TBM.
Other objectives
(a) To determine whether the doses of anti-TB drugs, prescribed according to weight bands, result in appropriate drug exposures when compared with historical paediatric and adult PK data.
(b) To further understand the pathophysiology of TBM in children and the effects of intensified antibacterial and anti-inflammatory treatment on intra-cerebral inflammation and the macroscopic complications of TBM (infarcts, tuberculomas, hydrocephalus).
|
Uganda |
2020-04-30 |
2023-04-30 |
Medical and Health Sciences |
|
Non-degree Award |
|
Annette Schuh Hildegard
ID: UNCST-2024-R003745
|
Evaluation and Transfer of mobile whole slide tissue scanners and liquid biopsies to deliver fast and precise diagnosis for improved outcomes of children and young adults with EBV-driven lymphoma: a joint Tanzanian and Ugandan Paediatric Oncology Network Initiative
REFNo: HS529ES
We have four objectives: to
1. Assess the diagnostic accuracy of liquid biopsy testing
2. Asses the diagnostic accuracy of digital pathology
3. Development of a digital pathology machine learning algorithm
4. Transfer of above novel tests and associated expertise to local laboratories
|
UK |
2020-04-24 |
2023-04-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
Peter Nkurunziza Munya
ID:
|
'Evaluation of The Bio-Rad Geenius HIV-1/2 Confirmatory Assay as Part of Confirmatory and Differentiation of HIV infection at Uganda Virus Research Institute-HIV Reference Laboratory'
REFNo: HS612ES
Primary objective
• To conduct an in-country evaluation of the performance of Geenius™ HIV-1/2 Confirmatory Assay for confirmation of HIV infection using DBS and Plasma specimens, as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo.
Specific objectives
• To determine the sensitivity of Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo
• To determine the specificity of the Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo
• To determine the positive predictive value and negative predictive value of Geenius™ HIV-1/2 Confirmatory Assay as compared to Murex HIV Ag/Ab Combination and/or Genscreen Ultra HIV Ag/Ab Combo.
|
Uganda |
2020-04-24 |
2023-04-24 |
Medical and Health Sciences |
|
Non-degree Award |
|
PROSPER BEHUMBIIZE
ID:
|
Implementation Research on Education Management Information Systems (EMIS) Data Use Innovations in Uganda
REFNo: SIR33ES
1. To assess the existing management information systems for the Education Sector
2. To understand how innovations including DHIS2 can be used to improve EMIS data quality, management and use at all levels of the education sector
3. To ascertain the best practices that will inform scale up of Dhis2-for Education within and across countries
|
Uganda |
2020-04-17 |
2023-04-17 |
Engineering and Technology |
|
Non-degree Award |
|
Peter Olupot-Olupot
ID:
|
Coronavirus Disease 2019 Open Cohort (COC) Study
REFNo: HS611ES
The specific objectives:
1. Through a cross sectional survey describe risk factors and enlist study participants for the cohort study.
2. To characterize the clinical spectrum of COVID-19.
3. To refine case definitions of COVID-19 using data from different population groups.
4. To explore in detail, the epidemiology of COVID-19.
5. To document outcomes associated with COVID-19 in various age groups, populations and concomitant conditions.
6. To generate data to inform clinical research on COVID-19.
7. To generate population specific data for evidence based public health education as a control measure.
8. Provide a decision tree that has automated feedback that has standard of care including quarantine, call help-line, seek medical attention and avoid spread of the disease.
|
Uganda |
2020-04-03 |
2023-04-03 |
Medical and Health Sciences |
|
Non-degree Award |
|
AGNES NAGGIRINYA BWANIKA
ID: UNCST-2019-R001126
|
Acceptability, effect and cost of mobile-health on art adherence among youths: a mixed methods sequential study in Kiryandongo
REFNo: HS576ES
General objective: To assess the acceptability, effect and cost of the Call For Life Uganda mHealth tool on ART adherence among youth initiating ART at Kiryandongo Hospital.
Specific objectives:
Objective 1a: To assess barriers, enablers of ART adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 1b: To assess acceptability of mHealth for HIV adherence among youth living with HIV in Kiryandongo Hospital at baseline & study end.
Objective 2: To assess effect of the CFLU mHealth tool on ART adherence among youths initiating ART at 6 and 12 months.
Objective 3: To evaluate the cost of the CFLU mHealth adherence tool in comparison to Standard of Care.
|
Uganda |
2020-03-28 |
2023-03-28 |
Medical and Health Sciences |
|
Degree Award |
|
Anthony Matovu
ID:
|
G - Therapy: Classical Mechanical Resonance Tool For HIV Cure
REFNo: SIR26ES
Main Objective
To design and implement an effective, safe, “isolate – and – kill†Classical Mechanical resonance tool for HIV – riddance from HIV – positive patients.
Specific Objectives
a) To outline a velocity, frequency and wavelength generating system based on scalable vibratory/circulatory dynamics pertinent with the vibratory characteristics of the HIV particles (H – 1 atom system is earmarked).
b) To identify the HIV virus by morphology (physical structure) differentiation using light optical nanoscopy – observation procedures (use flue virus for comparison).
c) To characterize the projected mechanical resonance – based fight between HIV and human defense system cells (realizable by articulating and relating factors implicated).
d) To design and implement a counter resonance tool against HIV’s own mechanical resonance combat weapon against human defense cells (achievable through determining rupture-prone resonant frequency-amplitude factors leading to an effective, safe body- penetrative capacity; as well as the functional body/specimen exposure period).
|
Uganda |
2020-03-20 |
2023-03-20 |
Engineering and Technology |
|
Degree Award |
|
Doreen Nakku
ID:
|
Assessment of knowledge and attitudes towards hearing loss and community utilisation of hearing screening services at a Health Centre IV in Mbarara District
REFNo: HS549ES
1. To assess knowledge on hearing loss and attitudes towards hearing loss of communities served by Bwizibwera HC IVs in Mbarara District
2. To assess the utilisation of hearing screening services at Bwizibwera HC IVs in Mbarara District.
|
Uganda |
2020-03-20 |
2023-03-20 |
Medical and Health Sciences |
|
Non-degree Award |
|
KAHUNZIRE EVANGELIST
ID:
|
Evaluation of parental involvement on primary pupils educational academic performance in public day primary schools of Ndorwa County,Kabale District-Uganda.
REFNo: SS426ES
To establish the relationship between parental involvement on primary pupils educational academic performance in selected public day primary schools of Ndorwa County,Kabale District-Uganda.
To examine the utilization of educational domains on primary pupils'educational academic performance in selected public day primary schools of Ndorwa County ,Kabale District-Uganda.
To formulate a parenting involvement model that enhances primary pupils'educational academic performance in selected public day primary schools of Ndorwa Ounty,Kabale District-Uganda.
|
Uganda |
2020-03-20 |
2023-03-20 |
Social Science and Humanities |
|
Degree Award |
|
Paddy Tukamuhebwa Mutungi
ID: UNCST-2020-R014201
|
Barriers and facilitators of investigation coverage among index tuberculosis case contacts in rural Mbarara district, Uganda.
REFNo: HS569ES
1. To identify the barriers of TB contact investigation coverage among contacts of TB index clients in three rural primary health facilities in Mbarara district in Uganda.
2. To identify the facilitators of TB contact investigation coverage among contacts of TB index clients in three rural primary health facilities in Mbarara district, Uganda.
|
Uganda |
2020-03-20 |
2023-03-20 |
Medical and Health Sciences |
|
Degree Award |
|
| View |
|
Sort By: |
|
|
|
| |
|