Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Buregyeya
ID: UNCST-2020-R014116
A Mobile Health Intervention with Transfer of Social Bundle Incentives to Increase Treatment Adherence in Tuberculosis Patients in Uganda
REFNo: HS656ES

1a: To identify perceptions, acceptability, perceived barriers and facilitators for the use of VDOT among TB patients, health providers and community DOT volunteer workers in Uganda.
1b: To adapt the VDOT platform to the local context using the information from the qualitative interviews and create the DOT Selfie intervention with automated social bundle incentives to reward adherence
2: To conduct a pilot randomized trial to compare treatment adherence between patients using DOT Selfie and in-person DOT

Uganda 2020-06-16 2023-06-16 Medical and Health Sciences Non-degree Award
Jennifer Palmer
ID:
The lives & livelihoods of displaced health workers in Uganda
REFNo: HS495ES

By studying the relationships between these global health trends, humanitarian HRH governance in Uganda, and the experiences of displaced HCWs, we aim to provide an in-depth case study of the political dynamics, contradictions and lived realities affecting HRH development in a contemporary refugee response. We do so to prompt debate in domestic and international policy circles which might lead to better inclusion of displaced HCWs in this and other humanitarian responses and, ultimately, explore avenues to improve the lives, livelihoods and future health systems of crises-affected populations.
Specific objectives of this work include:
Map HRH governance initiatives affecting displaced HCWs in Uganda alongside contemporary trends in the health and protection fields which influence HRH decision-making for displaced HCWs by policy actors.
Document the migration and livelihood trajectories of displaced HCWs in relation to their motivations and aspirations for health system building and self-reliance during their experiences of different phases of conflict and displacement.
Identify formal and informal bureaucratic practices which regulate HRH development for displaced HCWs as well as the networks, resources and solutions displaced HCWs draw on to secure access to health livelihoods.
Explore displaced HCW perceptions of the quality of public health responses for refugees in Uganda, including links between continuity of care for patients and continuity of practice for healthcare providers.
Through RECAP collaborators and other interested policy actors, contribute evidence and analyses that could improve employment of displaced HCWs to HRH governance initiatives and processes identified during the research process.

Canada 2020-06-12 2023-06-12 Medical and Health Sciences Non-degree Award
Anders Jensen
ID:
Digitizing Revenue Collection in Northern Uganda
REFNo: SS456ES

This project studies the introduction of a digital tax assessment and collection system into local tax administration in Northern Uganda. We will partner with the UNCDF and Ministry of Local Government to measure the impacts of the digitized system on the process of tax assessment and revenue collections relative to a status quo manual registration and collection system. To study how the digital system affects the accuracy of tax assessment, the research team will conduct independent, objective assessments of
taxpayers and match them to official records. This exercise will provide an opportunity to shed light on how gaps in assessment accuracy correlate with tax compliance to investigate how accuracy and perceived fairness in the
assessment step of taxation impact payment and revenues.
Denmark 2020-06-11 2023-06-11 Social Science and Humanities Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
Assessment of the feasibility of collection of COVID 19 Immune/convalescent Plasma in Uganda
REFNo: HS684ES

General objective
The overall objective of this project is to assess the feasibility collecting and storing of COVID-19 convalescent plasma (CCP) in Uganda.

Specific objectives
1. To determine the proportion of Ugandan COVID-19 survivors who consent for CP donation
2. To determine the levels of SARS-CoV-2 virus antibodies among Ugandan COVID 19 recoveries
3. To establish a biobank of well annotated and well characterized plasma aliquots from COVID 19 recovered patients for future biomedical studies
Uganda 2020-06-11 2023-06-11 Medical and Health Sciences Non-degree Award
Martin  Muhereza
ID:
Policy and Structural reforms of Electricity in Uganda in the context of social economic welfare
REFNo: SS424ES

1.To examine the alignment of electricity reforms in Uganda with theoretical benefits of power sector reforms
2. To analyze the relationship of electricity reforms with the levels of electricity accessibility,reliability,and affordability in informal settlements.
3.To generate knowledge beneficial to policy makers and planners interested in the contribution of electricity to the development trajectory
Uganda 2020-06-04 2023-06-04 Social Science and Humanities Degree Award
FREDRICK MAKUMBI
ID:
Performance Monitoring for Action (PMA) Uganda
REFNo: HS625ES

General objective
To monitor change in contraceptive availability and use in Uganda and increase understanding of the factors contributing to that change through panel surveys in order to support FP program monitoring and improve performance.

Specific objectives
Specifically, the project aims to conduct cross-sectional and panel surveys at the female, household, and service delivery levels, with a focus on actionable programmatic data on contraceptive availability and use dynamics in targeted geographic areas in order:
1. To measure and monitor key family planning indicators of programmatic relevance cross-sectionally on an annual basis including contraceptive prevalence rate and stocks of contraceptive commodities in Service Delivery Points serving the Enumeration Areas
2. To assess the determinants and consequences of contraceptive availability and use dynamics in Uganda.
3. To evaluate factors associated with a change in contraceptive use states including: Contraceptive acceptor (non-user to user), Contraceptive discontinuer (user to non-user), and Contraceptive switcher (user of one method to a different method)

Uganda 2020-06-04 2023-06-04 Medical and Health Sciences Non-degree Award
ANNET NAGUUDI
ID: UNCST-2022-R009395
CLIENT EXIT INTERVIEWS (CEIs) UNDER THE WOMEN INTEGRATED SEXUAL HEALTH (WISH) PROGRAMME IN UGANDA
REFNo: HS591ES

The specific objectives are to:
1. Characterize users of family planning (FP) services
2. Estimate the percentage of users of FP services by WISH (Women Integrated Sexual Health) service delivery points who are under-age 20
3. Estimate the percentage of clients of FP services provided by WISH service delivery points who are living in poverty
4. Provide information needed to estimate the number of additional users of modern methods of contraception contributed by WISH
5. Estimate the percentage of WISH FP clients counselled on a range of methods and potential side effects as defined by the method information index
6. Estimate the percentage of FP clients who would recommend the WISH services as evidenced by the net promoter score (NPS)
7. Estimate the percentage of WISH clients who demonstrated positive attitudes, practices and community support in relation to FP and SRHR
8. Estimate the percentage of FP clients at WISH service delivery points reporting exposure to WISH social and behavioral change communication (SBCC) activities
9. Estimate the percentage of users of FP services by WISH service delivery points who have a disability.
10. Understand why FP users changed methods
11. Explore the predictors of FP adopters
12. Explore the predictors of being likely to promote FP services
13. Determine effect of Social and Behavior Change Communication (SBCC) campaign on outcomes of interest

Uganda 2020-06-01 2023-06-01 Medical and Health Sciences Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
Uganda Virus Research Institute Performance Evaluation for COVID-19 Diagnostic tests
REFNo: HS637ES

Overall objectives
The overall objectives of this performance evaluation are:
- To verify the performance characteristics of new on-the-market NAATs,
- To evaluate the performance characteristics of new, on-the-market, EIAs and RDTS (IgA, IgG and IgM),
- To train laboratory and POC staff in the country in biosecurity and the required technical skills to perform COVID-19 diagnostic testing,
- To establish serum/plasma panels of well-characterized COVID-19 sera/plasma to support evaluation efforts.

Specific Objectives:
- To confirm whether or not a new NAAT complies with the manufacturer’s specifications,
- To determine the performance equivalence of new on-the-market NAATs using the Berlin protocol NAAT as the gold standard,
- To determine the sensitivity and specificity of new on-the-market diagnostic EIAs and RDTs against a gold-standard method,
- To evaluate the operational characteristics of new on-the-market immunoassays. Operational utility characteristics that may be considered include;
o ease of performance
o specimen type utility
o inter-reader variability
o reaction endpoint stability
o suitability for use in facilities with limited infrastructure (no/limited electricity, no/limited clean water, inadequate means of biosafety disposal)
- To document Standard Operating Procedures (SOPs) and train laboratory staff in the country in performing COVID-19 diagnostic testing using recommended EIAs and RDTs,
- To establish serum panels of well characterized COVID-19 sera/plasma to support future validation and evaluation of immunoassays.


Uganda 2020-05-20 2023-05-20 Medical and Health Sciences Non-degree Award
Badru Bukenya
ID:
Displaced communities, environmental degradation and sustainable livelihoods in Uganda

REFNo: SS310ES

(i) understand the various ways in which refugees and nationals living in or around new and long-term refugee settlements interact with the environment and ecosystem services.
(ii) explore the variety of knowledges (indigenous; cultural, social and economic) and needs (shelter, food, water, sanitation) of refugee and local households for understanding how the environment is used.
(iii) examine the nature and extent of environmental degradation (loss of forests/fragmentation and soil degradation) in different camp settlements. And,
(iv) offer recommendations for the management of increasing pressure on land resources within sustainable livelihood practices for development and policy programming.

Uganda 2020-05-08 2023-05-08 Social Science and Humanities Non-degree Award
Hussein Kafeero Mukasa
ID:
HEPATITIS B GENOTYPES AND IL-2, 4, 10, INF-γ, TNF-α, PROMOTER GENE POLYMORPHISMS IN A HIGH AND LOW ENDEMIC REGION OF UGANDA
REFNo: HS575ES

1. To determine the circulating hepatitis B virus genotypes in regions of high and low endemicity in Uganda.
2. To characterize Th1/Th2 cytokine gene promoter polymorphisms among HBV unexposed and exposed individuals in low and high endemicity regions.
3. To investigate the relationship between hepatitis B virus genotype and the observed Th1/Th2 cytokine gene promoter polymorphisms
4. To determine the expression levels of the cytokines and correlate them with the infecting genotypes and the single nucleotide polymorphisms in the Th1/Th2 cytokine gene promoter.


Uganda 2020-04-30 2023-04-30 Medical and Health Sciences Degree Award
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