Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Peter Rukundo Milton
ID: UNCST-2020-R014799
Nutritional Quality and Safety of Complementary Foods for Children in Landslide-prone Bududa District
REFNo: HS982ES

(i) Describe the diversity of meals and food combinations commonly used in the complementary feeding of children 6-23 months old in Bududa district. (ii) Analyse the nutrient and chemical composition of commonly used raw and cooked complementary foods. (iii) Identify the type and levels of micro-organisms in the food and water commonly used for complementary feeding.
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-degree Award
Suzanne  Kiwanuka N
ID: UNCST-2020-R014671
COVID-19: Assessment of the COVID-19 Response in Eastern, Central and Western Africa
REFNo: HS1121ES

The aim of this research is to assess and curate the (i) response to the COVID-19 pandemic in Africa and the outcomes in terms of COVID-19 control and (ii) continuity of essential non-COVID-19 services within the COVID-19 period, to inform the COVID-19 response and recovery as well as health system resilience to future disease outbreaks in Africa.
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-degree Award
Diane Nabikolo
ID:
DEVELOPMENT OF A SAFE READY TO EAT BHAJIA SNACK FORTIFIED WITH GRASSHOPPER (Ruspolia differens) FLOUR IN UGANDA
REFNo: A121ES

i. To establish food safety knowledge, attitudes and indigenous practices associated with safe harvesting and processing of R. differens at the household level.
ii. To determine potential allergens associated with R. differens and prevalence of allergic reactions from their consumption and handling
iii. To evaluate the effect of processing on quality and safety of bhajia snack enriched with R. differens flour
iv. To determine consumer preferences and willingness to pay for value-added ready to eat bhajia snack fortified with R. differens flour.

Uganda 2021-07-28 2024-07-28 Agricultural Sciences Non-Clinical Trial Degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
Pregnancy Associated Tuberculosis: Immunological and Clinical Outcomes of Exposed Infants.
REFNo: HS1396ES

4. To determine TB treatment outcomes of mothers with pregnancy associated tuberculosis.,3. To determine the prevalence of maternal comorbidities such as hyperglycaemia, malaria, HIV, syphilis and anaemia.,2. To explore the concept of congenital TB (defined as TB acquired during the intrauterine period or during the normal birth process) among infants born to women with active TB.,Secondary objectives 1. To estimate the prevalence of active TB among pregnant and postpartum mothers seeking care from antenatal clinics and TB treatment units.,3. To describe the clinical outcomes of the women with pregnancy associated TB (defined as a diagnosis of TB during pregnancy or within six months of the postpartum period) and their exposed infants at the different time points. ,2. To explore, in a subset of infants, T cell, B cell and NK cell responses following stimulation with TB antigens.,Primary objectives 1. To compare antibody vaccine responses to BCG, measles, tetanus among children born of mothers diagnosed with TB infection or disease during pregnancy or mothers on TB treatment within a six months’ postpartum period.,To compare antibody vaccine responses in children born of mothers diagnosed with diagnosed with TB infection or disease during pregnancy or mothers on TB treatment within a six months’ postpartum period.,
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Izudi
ID: UNCST-2019-R000469
Evaluating the acceptability of the Aqua Research STREAM Disinfection Generator in healthcare facilities in Uganda
REFNo: HS1467ES

The proposed acceptability study will evaluate levels of user and key stakeholder acceptability of the STREAM at the end of the initial introduction stage. Results will inform national STREAM introduction strategies
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Baluku B
ID: UNCST-2019-R000612
Prevalence of Soil transmitted HElminths and correlation with Cardiovascular risk factors among patients with drug resistant TuBerculosis in Uganda: a cross sectional multi-center study (SHEC-TB study)
REFNo: HS1521ES

2. To establish the correlation between soil transmitted helminths co-infection and BMI, HbA1C, blood pressure, serum lipids and the CVR score among patients with DR-TB in Uganda,1. To determine the burden of soil transmitted helminths co-infection among patients with DR-TB in Uganda,
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
William Worodria Ofuti
ID: UNCST-2022-R010915
Rapid Research in Diagnostics Development for TB Network (R2D2 TB Network) Study
REFNo: HS1482ES

1. To evaluate early and late prototypes of novel TB diagnostics to provide feedback to developers on performance and usability, inform further development and identify potential strategies for use in endemic settings.
2. To conduct large-scale, multi-center assessments of the accuracy and usability of design-locked novel TB diagnostics, including in special populations, to facilitate World Health Organization (WHO) policy review.
3. To assess the potential costs and epidemiological impact of novel TB diagnostics alone or in combination with current tests and algorithms to inform their further assessment and/or the WHO policy review process.
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Rhona Baingana Kezabu
ID: UNCST-2021-R013638
THE 2021 DHS-8 PILOT
REFNo: HS1529ES

To compare hemoglobin concentrations between venous blood, a single drop of capillary blood, and a pooled capillary blood sample in children age 6-59 months and non-pregnant women age 15-49 in a laboratory setting and a field setting,To program and pilot collection of other types of data (for assessing/ensuring interview data quality),To improve various aspects of the CAPI data capture process,To test the computer-assisted personal interviewing (CAPI) data collection application for new sections of the questionnaire ,To understand the performance of selected new core questions and modules with respect to aspects that can be assessed through cognitive interviewing: comprehension, retrieval, judgement, and response,To test selected core questions, new modules, the Domestic Violence module, and a number of the CAPI innovations under field conditions for the eighth round of The Demographic and Health Surveys (DHS) Program. ,
Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Gertrude Namale
ID:
Post-discharge Care for Stroke patients in Uganda: barriers and enablers of appropriate secondary preventive care, coping mechanisms and access to rehabilitation service
REFNo: HS1522ES

Overall aim
To improve the quality of life of stroke survivors in Uganda by examining the barriers and enablers of appropriate care and support following discharge from hospital.

Specific objectives
1. To examine the barriers and enablers of stroke survivors’ participation in self-reported home-based physical activity and adherence to clinic follow-up schedules post-discharge

2. To document the experiences and opinions of facility-based health care providers on post-discharge follow-up and care for stroke patients

3. To describe the coping mechanisms among stroke survivors and their caregivers after discharge (a) adjustment to lifestyle behaviour post-stroke b) needs and concerns; c) depression symptoms

4. To document barriers and facilitators related with access to rehabilitation services among stroke patients post-discharge

Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edgar Agaba
ID:
A framework for improving the effectiveness of integrated nutrition interventions in Uganda
REFNo: HS1549ES

1. Evaluate the program design, selected nutrition, and health outcomes among women and children under 5 years at baseline and at the end of the Community Connector interventions.
2. Explore the experiences of the implementers and the beneficiaries of the Community Connector interventions.
3. Evaluate the effectiveness of the Community Connector interventions on nutrition and health outcomes among women and children under 5 years.
4. Develop and validate a framework for improving effectiveness of integrated nutrition interventions for implementation in resource-poor settings.

Uganda 2021-07-28 2024-07-28 Medical and Health Sciences Non-Clinical Trial Degree Award
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