Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Firminus  Mugumya
ID:
Measuring the Impact and Sustainability of a Community-Based Child Protection Approach in Prevention of Violence Against Children in a Post Conflict Setting in Northern Uganda.
REFNo: SS566ES

The overall question for this evaluation is: What is the impact and sustainability of interventions to strengthen community-based child protection systems on prevention of violence against children in families and communities emerging from a protracted armed conflict?

The specific questions are:
•Does training Child Protection stakeholders result into functional community-based Child Protection systems for prevention of violence against children?
•Does an equipping child protection structure with knowledge, skills, financial and material resources on case management improve access to child protection services?
•Does legislation and dissemination of relevant child protection laws lead to improved implementation and enforcement for prevention of violence against children?
•Does equipping children with knowledge and skills in child protection, make them indispensable change agents for addressing violence against children?
•What evidence exists to show that the project interventions to prevent violence against children at family and community level in post-conflict setting will be sustainable?
•What are the critical enablers of project success, and what should be avoided for future similar interventions in and out of post-conflict settings?
•How sustainable are interventions interventions to strengthen community-based child protection systems?

Uganda 2020-11-25 2023-11-25 Social Science and Humanities Non-degree Award
Ronald Mulondo Mulondo
ID:
Spatiotempoaral Characterization of Congenital Myelomeningocele in Uganda
REFNo: HS763ES

1.To provide a basic description of the MMC dataset at CURE Hospital, characterizing the geographical and temporal distribution.
2.To examine whether the incidence of MMC in Uganda is non-uniform or not.
3.To examine the association between MMC case incidence and rainfall.

Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Benjamin Atwine
ID:
Knowledge and risk factors of Hepatitis B disease among women attending Antenantal Care ate Arua Regional Referral Hospital, Uganda.
REFNo: HS785ES

General Objective
To determine the level of available knowledge and risk factors associated with Hepatitis B disease among pregnant women attending ANC at ARRH.
Specific Objective
1. To determine the percentage of women attending ANC at ARRH who are knowledgeable about Hepatitis B disease.
2. To determine the prevalence of Hepatitis B disease among pregnant women attending ANC at ARRH who take part in the study.
3. To determine the risk factors of Hepatitis B disease among pregnant women seeking ANC at ARRH.
Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Degree Award
Kenneth Ssebambulidde Ssebambulidde
ID: UNCST-2021-R013976
Collection of control DNA samples for the AMBITION-cm host-susceptibility to cryptococcal infection sub-study (a genome wide association study). A sub-study of the AMBITION-cm Trial
REFNo: HS789ES

To identify genetic variants associated with Cryptococcal meningitis susceptibility and disease severity
Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
THE EFFECT OF COVID-19 OUTBREAK ON ONGOING RESEARCH PROCESSES IN UGANDA: KEY STAKEHOLDER’S EXPERIENCES, OPINIONS AND COPING STRATEGIES
REFNo: HS910ES

1.To explore the experiences of key stakeholders involved in research during Covid-19 outbreak in Uganda
2.To explore opinions and strategies regarding conduct of research during epidemic outbreaks in Uganda.

Uganda 2020-11-24 2023-11-24 Medical and Health Sciences Non-degree Award
Viola Karungi
ID:
Critical Theatre: An Analysis of Plays Representing the concepts of Violence, Injustice and the nature of Imperialism in regard to the War (1987-2006) in Northern Uganda.
REFNo: SS605ES

The major research question for the study is:
i. How do the plays Silent Voices, Forgotten World and Forged in Fire about the war in northern Uganda contribute to understanding the role of contemporary critical theatre in light of Uganda’s history of critical theatre?
The sub-questions are:
i. How do the plays represent the concept of violence on victims of the war in northern Uganda?
ii. How do the plays expose the nature of imperialism by the donor countries and institutions from the West that gave donor and humanitarian aid during the war and in its immediate aftermath?
iii. How do the plays represent the concept of injustice and how it is shaped by violence and imperialism regarding the war in northern Uganda?


Uganda 2020-11-23 2023-11-23 Social Science and Humanities Degree Award
Stella Neema
ID: UNCST-2019-R000814
Evaluation of UNICEF’s District Health Systems Strengthening Initiative (DHSSi) – Uganda Study Protocol
REFNo: SS613ES

The overall objectives of the evaluation are twofold:
• To improve intervention design and management, and
• To inform decisions about future investment and scale-up by establishing evidence of the results and impact of the intervention.
These overall objectives are further broken down into specific objectives:
• Assess whether interventions were implemented according to the work plan and measure the strength of the implementation.
• Examine district health governance and management capacity.
• Identify key lessons learned and provide actionable and evidence-based recommendations for improvements and scale-up.

Uganda 2020-11-23 2023-11-23 Social Science and Humanities Non-degree Award
DOROTHY NAKIMBUGWE NAKIMBUGWE
ID:
Impact of COVID19 lock down and, effectiveness of supplementary feeding on the nutrition status of mothers and their malnourished breastfeeding children, attending nutrition Units of health facilities in Kampala and Wakiso – a pilot study to inform national and organizational policies and interventions
REFNo: HS984ES

a) Assess the impact of the COVID19 lockdown and social distancing requirements on the nutrition status of mothers of children attending nutrition clinics at health centers and their access to food in Kampala and Wakiso districts through individual interviews using a semi-structured questionnaire.
b) Determine the effectiveness of a locally produced nutrient-enhanced composite porridge flour for improving the nutrition status of mothers and their breastfed malnourished children.
Uganda 2020-11-23 2023-11-23 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES

The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Chioma Adeyemi Njideka
ID:
Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES

The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.

Nigeria 2020-11-20 2023-11-20 Social Science and Humanities Degree Award
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