Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
 An open-label, multicentre, randomized, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild/moderate cases of COVID-19
REFNo: HS1789ES

Primary objective: to compare the efficacy of alternative treatment strategies versus control on the risk of progression to severe respiratory disease
The secondary objectives are:
 To compare the safety of each study arm to control, up to Day 21 of follow-up
 To compare the rate of hospitalizations due to COVID-19 in each study arm versus control
 To compare the time to hospitalization due to COVID-19 in each study arm versus control
 To compare the rate of hospitalizations for other reason than Covid-19 in each study arm versus control
 To compare the disease-free rate in each study arm versus control
 To compare the death rate in each study arm versus control
 To compare time to worsening of SpO2 < 93in each study arm versus control
 To compare the capacity to prevent severe progression between study arms
 To identify risk factors for severe progression
 To assess efficacy in sub-groups of patients e.g. with pre-existing conditions/co-morbidities, by age group, sex, BMI, timeframe between onset of symptoms and randomization.

 Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Clinical Trial Non-degree Award
Herbert Muyinda
ID: UNCST-2019-R000373
 Cango Lyec Study (Healing the Elephant): Developing and Testing Interventions to Reduce HIV Risk, Increase Access to Treatment and Promote Resilience in War Affected Populations in Northern Uganda (Follow-up Study)
REFNo: HS1816ES

To pilot the feasibility and acceptability of Wayo/Nero and mHealth intervention packages to support both prevention and care for HIV/AIDS, Hepatitis B, and war related trauma.,Investigate associations between posttraumatic stress, resilience, and depression, with HIV/Hepatitis B incidence among conflict-affected populations in Northern Uganda,Estimate prevalence and incidence of HIV, syphilis, Hepatitis B, and identify associated risk factors among conflict-affected populations in Northern Uganda ,Our overarching goal is to develop, test and scale up culturally-safe, strengths-based, trauma-informed, technology-enhanced (CSTT) interventions among war affected populations. ,
 Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Wakida K
ID: UNCST-2019-R001225
 Enhancing the Capacity for Providers in Mental Health Integration (ECaP-MHI): A pilot intervention study in Lira district, Northern Uganda
REFNo: HS1847ES

1.4.1 To gather baseline data on the mental disorder diagnoses recorded by PHCPs at a selected HC IV in Lira district before the pilot intervention (in objective four)
1.4.2 To explore contextual barriers and/or challenges likely to affect the ability of Lira DHMT to support PHCPs using the adapted ECaP-MHI intervention
1.4.3 To adapt the training component of the ECaP-MHI intervention
1.4.4 To assess implementation of the DHMTs supporting PHCPs to integrate mental health
services into using the adapted ECaP-MHI intervention
Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tana Chongsuwat
ID:
Evaluation of Understanding, Perceptions, and Attitudes Toward Cervical Cancer Screening, Prevention, and Treatment Services Available to Women in Gulu City, Uganda
REFNo: HS1862ES

Understand attitudes and perceptions regarding seeking cervical cancer screening, treatment, or prevention services.,Assess the level of knowledge of men and women on cervical cancer etiology, risk factors, screening, and prevention services available to them.,
 USA 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R011972
 Adaptive immunity to Mtb-infection and TB disease among young Ugandan children”
REFNo: HS1870ES

1.To recruit Ugandan children 5 years and younger (< 60 months), with and without perinatal HIV-exposure and/or infection, who are household contacts of an adult with confirmed TB disease
2.To identify immunologic phenotypes that correlate with TB disease, versus remaining asymptomatic following TB household contact, in young children with and without perinatal HIV-exposure and/or infection
3.To determine if MTB-specific T cell and/or antibody profiles can be used to distinguish TB disease from asymptomatic MTB infection, in young children with and without perinatal HIV-exposure and/or infection
4.To determine how perinatal HIV exposure/infection alters MTB-specific adaptive immune profiles

 Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Muhindo
ID:
Tackling coronavirus disease-2019 Vaccine Hesitancy among People Living with HIV in Kampala, Uganda
REFNo: HS1902ES

To describe the prevalence and factors associated with COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
2. To explore the drivers of COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
3. To develop and pilot educational materials to promote COVID-19 vaccine uptake among adult PLHIV in Kampala, Uganda

 Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 Voluntary stool collection for optimizing laboratory techniques at the MRC/UVRI and LSHTM Uganda Research Unit
REFNo: HS1910ES

Objectives of the research project:
• To obtain Schistosoma mansoni ova for training and optimisation of the process of miracidia hatching and snail infection
• To obtain S. mansoni ova for training and optimisation of the process of sex determination of cercariae
• To develop materials such as S. mansoni DNA that can be used as reagents and/or positive controls.
• To make available S. mansoni materials for use in the routine evaluation of proficiency of assays and for the testing of reagents and new assay kits

 UK 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
CHRISTINE MBABAZI -MPYANGU
ID:
Thriving Together: Creating Social Support Groups for the Reintegration and Empowerment of Formerly Abducted Women in Northern Uganda
REFNo: SS965ES

1) Assess the current social, economic and psychological status of formerly abducted women in Northern Uganda as compared to never abducted comparable women
2) Scientifically test the effectiveness of women’s support groups in facilitating the reintegration of formerly abducted women, raising their aspirations, creating economic opportunities and increasing their overall well-being.
Uganda 2021-12-06 2024-12-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
DEVELOPMENT OF AFFORDABLE, EASY TO USE, AND RAPID POINT OF CARE DIAGNOSTIC TESTING PLATFORMS FOR COVID-19 SUITING REMOTE SETTINGS OF SUB-SAHARAN AFRICA.
REFNo: HS1648ES

1.To optimize and validate reagents (recombinant peptides, monoclonal and polyclonal antibodies)’s performance towards capture of SARS- CoV 2 virus antigen and host specific antibodies
2.To develop prototypes of lateral flow immunochromatography test (LFT) and tube-agglutination test platforms for COVID19 testing
3.To perform In-dependent validation of the developed test platforms.


Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayebazibwe Kakoba Gloria
ID:
Determinants of uptake of Mass Drug Administration for schistosomiasis control in Butiaba, Uganda
REFNo: SS1083ES

1. To determine the uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda 2. To examine socio demographic characteristics associated with uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda. 3. To assess barriers related to knowledge that are associated with uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda. 4. To assess barriers related to attitudes that are associated with uptake of Praziquantel during Mass Drug Administration for schistosomiasis control among adults in Butiaba, Uganda
 Uganda 2021-12-03 2024-12-03 Social Science and Humanities Non-Clinical Trial Degree Award
Catherine Birabwa
ID: UNCST-2021-R012851
 INCREASING COVERAGE AND UPTAKE OF VOLUNTARY FAMILY PLANNING IN EMERGENT TOWNS AND CITIES IN UGANDA – THE CASE OF JINJA AND IGANGA
REFNo: HS1826ES

General objective To contribute to the reduction of unmet of unmet need and increased use of VFP in urban settings by adapting high-impact practices in FP and developing and testing a tailored package of interventions to increase coverage and uptake of VFP services in emerging urban areas. The project also aims to contribute to improved performance of urban health systems in the study sites with regard to VFP. Specific objectives Implementation objectives i. To develop and implement a tailored package of high-impact interventions fit for emerging urban settings in Uganda using participatory approaches ii. To improve understanding of FP and decision-making capacity for healthy reproductive or contraceptive behaviors; strengthen effective delivery and management of FP services. Research objectives i. To explore the current coverage of VFP and barriers and facilitators of contraception use in emergent urban settings in eastern Uganda ii. To assess the effectiveness, facilitators and barriers of the proposed intervention package in improving VFP service provision, accessibility and utilization iii. To explore how unintended pregnancies/birth could be associated with child survival and childhood health care in urban settings
 Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Arinaitwe
ID:
News Media Presentation Of Basic Education Teachers during the COVID-19 Pandemic: A Content Analysis of the Daily Monitor and the New Vision in Uganda.
REFNo: SS1068ES

1. To examine how teacher story coverage in the The Daily Monitor and The New Vision relates to the frames and themes of the research in the space of May 2020 to August 2020 during the COVID-19 pandemic.
2. To identify the frames of teacher stories in the The Daily Monitor and The New Vision in Uganda between May 2020 to August 2020 during the COVID-19 pandemic.
3. To examine the major themes of teacher stories that were published in the The Daily Monitor and The New Vision in Uganda newsrooms between May 2020 to August 2020 during the COVID-19 pandemic.
Uganda 2021-12-03 2024-12-03 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Kajumbula Mawerere
ID: UNCST-2019-R001531
 Low-interventional, multi-centre study of the burden of nosocomial infections among hospitalised patients in sub-Saharan Africa
REFNo: HS1880ES

Aim:
To assess antimicrobial resistance rates, as well as clinical outcomes (including treatment outcomes, mortality rate, hospital length of stay), healthcare resource utilisation (HCRU) and associated costs among hospitalised patients with nosocomial infections at Mulago Specialised Referral Hospital.

Study Objectives:
1. To estimate the prevalence of resistance in nosocomial infections(NI) amongst patients hospitalized at Mulago Specialized Referral Hospital
2. To describe treatment outcomes amongst hospitalized patients with NI, at the end of therapy and at hospital discharge
3. To assess mortality rates (all-cause & infection-related) of hospitalized patients with NI, at the end of therapy & at hospital discharge
4. To assess hospital length of stay amongst hospitalized patients with NI.

Secondary Study Objectives
1. To describe treatment outcomes amongst hospitalized patients with NI at Day 14/30 post-treatment initiation
2. To assess mortality rates (all-cause and infection-related) of hospitalized patients with NI, at Day 14/30 post-treatment initiation
3. To assess ICU length of stay amongst hospitalized patients with NI.
4. To describe the characteristics of hospitals participating in the study
5. To assess HCRU and associated costs post-hospitalization amongst hospitalized patients with NI
6. To assess the nursing care demand amongst hospitalized patients with NI

 Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Peter Olwoch
ID: UNCST-2021-R013221
 Antimicrobial resistance sentinel surveillance at Tororo General Hospital (TGH), Uganda with a focus on bacterial urinary tract infections and gonorrhoea infections
REFNo: HS1881ES

To identify bacteria causing UTI in patients who present to TGH and determine their antibiotic susceptibility profiles

To determine the antibiotic susceptibility of Neisseria gonorrhoeae isolates cultured from genital swabs from patients who present to TGH

To determine associations between patient characteristics, treatments prescribed, and clinical outcomes, with identified bacterial isolates and their susceptibility profiles

 Uganda 2021-12-03 2024-12-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Caroline Morogo Jerop
ID:
WUSC’s Volunteer Cooperation Program - IGNI+E Baseline Assessment
REFNo: SS835ES

The purpose of the baseline study for WUSC’s IGNI+E Project is to help the program staff and partners focus on program achievement related to a limited set of expected outcomes; and to empower partners to collaboratively measure and review these outcomes. Aligned with this purpose, the baseline study is designed to help the project achieve four specific objectives:
● To better understand the implementation context for the project at the onset of implementation
● To inform the performance measurement framework (PMF) by validating a SMART set of indicators, and establishing baselines for these performance measures
● To provide the foundation for a comprehensive results-based monitoring, evaluation, research, and learning (MERL) plan for the project

 Kenya 2021-12-02 2024-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Richard Wamimbi Wotti
ID:
Developing a National child focused policy research agenda (2021-2025)
REFNo: SS1018ES

a) Undertake a review of the current National Child Focused Policy Agenda (2015-2020) b) Develop a new National Child Focused Policy Agenda (2021-2025),
 Uganda 2021-12-02 2024-12-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Catherine Mwesigwa
ID: UNCST-2019-R000988
 Commercial Baby Food Consumption and Complementary Feeding Practices in Kampala
REFNo: HS1784ES

To explain the motivations for use of commercial baby foods among caregivers of infants and young children between 6-36 months in Kampala,To determine the proportion of caregivers that use commercial baby foods among infants and young children between 6-36 months in Kampala ,To determine the level of commercial baby food use for complementary feeding and the associated factors in an urban/peri-urban Ugandan sub-population of caregivers of infants and young children between 6-36 months in Kampala. ,
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Assessment of the HIV/AIDS legal, regulatory, and policy environment for key populations in Uganda
REFNo: HS1925ES

5 To develop recommendations on how the legal and policy framework affecting Key Populations can be improved to promote an enabling legal environment for the national response to HIV, particularly for key populations. ,4 To determine the extent to which the legal framework protects rights and promotes an enabling legal environment for the national response to HIV, particularly for people living with and affected by HIV and key populations. ,3 To analyze access to justice and law enforcement on HIV and human rights among key population and key service providers, access to legal support services, and law enforcement mechanisms. ,2 To assess the critical human rights issues affecting key populations and the extent to which the current environment addresses these.,1 To analyze existing HIV, health, and other related laws, regulations, and policy initiatives that impact the HIV response among key and priority populations in Uganda.,
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Ssekitoleko
ID: UNCST-2019-R001716
 Laparoscopic Cases Database
REFNo: HS1909ES

The second aim of the study is to use this data in a future project examining new low-cost laparoscopic equipment. ,The first aim of the study is to compare laparoscopic practices in several countries. ,This study aims to examine current laparoscopic practices in Uganda and the United States.,
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
 Validating a 10-minute instrument-free prototype HIV p24/p37 assay for early infant diagnosis
REFNo: HS1854ES

Objectives of the research project:

Primary objectives
1. To determine the sensitivity of a novel instrument-free HIV p24 PoC assay
2. To determine the specificity of a novel instrument-free HIV p24 PoC assay
3. To determine the accuracy of a novel instrument-free HIV p24 PoC assay
4. To determine the positive predictive value of a novel instrument-free HIV p24 PoC assay
5. To determine the negative predictive value of a novel instrument-free HIV p24 PoC assay

Secondary objective
1. To determine the agreement of the novel instrument-free HIV p24 PoC assay results between two independent laboratory technicians.

15. Brief outline of research study design/methods:

 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ayiorwoth Harriet
ID:
Exploring academic-practitioner knowledge sharing in higher education institutions: A study of Uganda Management Institute
REFNo: SS1102ES

1. Explore the benefits that UMI academic staff and practitioners gain from sharing knowledge. ,1. Find out how UMI academic staff and practitioners address the challenges that they face in sharing knowledge. ,Establish the challenges that UMI academic staff and practitioners face in sharing knowledge,Explore how UMI academic staff and practitioners share knowledge,The purpose of this study is to explore and gain an in-depth understanding of academic-practitioner knowledge sharing at UMI,
 Uganda 2021-12-02 2024-12-02 Social Science and Humanities Non-Clinical Trial Degree Award
Alfred Ecega Guli
ID:
HUMANITARIAN FOOD ASSISTANCE AND NUTRITION OUTCOMES AMONG CHILDREN UNDER FIVE YEARS IN UGANDA: A CASE OF SELECTED REFUGEE SETTLEMENTS IN WEST NILE.
REFNo: HS1912ES

1. What is the effect of food in-kind assistance on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 2. What is the effect of the cash-based transfer on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 3. What is the influence of agricultural inputs support on the nutrition outcomes among children under five years in selected refugee settlements in West Nile? 4. What is the effect of nutritional factors on humanitarian food assistance and nutrition outcomes among children under five years of age in selected refugee settlements in West Nile?
 Uganda 2021-12-02 2024-12-02 Medical and Health Sciences Non-Clinical Trial Degree Award
michael taylor halford
ID:
Dry Rifting in the Albertine -Rhino graben (DRIAR)
REFNo: NS260ES

To conduct geological investigation of faulting associated with continental rifting in the magma poor rift environment in the northernmost western branch of the East African Rift System.
 USA 2021-12-01 2024-12-01 Natural Sciences Non-Clinical Trial Degree Award
David  Sam Lackland
ID:
The psychological well-being of school-age South Sudanese children living in a refugee camp in Uganda
REFNo: SS938ES

RATIONALE
To the best of our knowledge, there are few studies trying to understand how South Sudanese refugee children thrive in settlements in Uganda, limiting the insight into their overall psychological well-being. Therefore, this study seeks to obtain a better understanding of how South Sudanese school-age refugee children experience their life in a refugee settlement in Northern Uganda.
The forced displacement of children implicates coping with and adapting to scenarios and situations that can be detrimental to a child’s normal development and well-being. To understand how children cope with the overall forced migration experience can contribute to find solutions to mitigate or reduce the potentially negative impact it has on children’s psychological well-being and mental health. By improving the knowledge about children’s experiences in refugee settlements, this study ultimately wishes to contribute with evidence that can facilitate the design and implementation of children friendly activities and environments in refugee settlements.
OBJECTIVES
In order to achieve the overarching aim mentioned before, this study plans to:
• observe how children play and socialize with each-other;
• understand how children learn in the refugee camp;
• explore how children cope emotionally with the different challenges caused by forced migration.
 Norway 2021-12-01 2024-12-01 Social Science and Humanities Non-Clinical Trial Degree Award
Macreen Mudoola
ID:
HRL Mid term and end of program evaluation protocol
REFNo: HS1701ES

to assess the progress of the project
 Uganda 2021-12-01 2024-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R012739
 Enhancing Integrated Management of Acute Malnutrition with Family MUAC and Implementation Science in West Nile Region in Uganda - Implementation Guideline Research Proposal
REFNo: HS1828ES

5. To assess the impact of IMAM Family MUAC on access, coverage of OTC and ITC and quality of care.,4. To determine the retention level of family caregivers and VHTs in detection and referral of children with acute malnutrition.,3. To determine the effectiveness of IMAM Family MUAC in detection and referral of acute malnutrition ,2. To assess the barriers and facilitators of IMAM Family MUAC implementation in in health facilities and communities in five districts in West Nile,1. To determine the uptake of IMAM Family MUAC in health facilities and communities in five districts in West Nile,To establish the feasibility and evaluation of the implementation process and effectiveness of IMAM Family MUAC to improve access, coverage, and quality of care in OTC and ITC services,
 Uganda 2021-12-01 2024-12-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sina Kulwijira Sosthenes
ID:
Proportion of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
REFNo: HS1552ES

To determine proportional of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Muhmood Kiryowa Haruna
ID:
Periodontal disease in diabetic patients attending Kiruddu Referral Hospital, Kampala: Prevalence, Factors and Association with Glycemic control and Insulin resistance
REFNo: HS1853ES

1) To determine the prevalence and factors associated with periodntal disease in patients with diabetes mellitus
2) To determine the bacteria associated with periodntal disease in patients with diabetes mellitus
3) To determine the association between periodntal disease and insulin resistance in patients with diabetes mellitus
 Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Victoria Namuggala Flavia
ID: UNCST-2019-R000991
 Young Women and Men’s Aspirations and Resilience: Prospects for Livelihoods, Employment and Accountability before, during and beyond COVID – 19
REFNo: SS1093ES

The overall objective of this project is to explore and interrogate the aspirations and resilience of young women and men in Africa; how these may or may not have shifted through the COVID-19 crisis and the implications presented for public policy in Africa with case studies in Ethiopia, Ghana, Kenya, Nigeria, Rwanda, Senegal and Uganda. Specific objectives are to:
1. Examine Ugandan young women and men’s aspirations for their futures.
2. Identify and analyse gender and social norms that guide the lives and aspirations of young men and women in Uganda.
3. Establish whether young women and men’s aspirations have changed with the advent of COVID-19.
4. Analyse what the young women and men are experiencing in their lives and livelihoods in a COVID-19 world.
5. Determine the extent to which the various provisions, regulations and policies in the study countries are aligned with young women and men’s aspirations and ideas about what they see themselves doing in the future.
6. Document lessons learned about the adaptability and resilience of young women and men’s aspirations.

Uganda 2021-11-30 2024-11-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
 Controlled Trial of Game Changers: A Group Intervention to Train HIV Clients to be Change Agents for HIV Prevention in Uganda
REFNo: HS1896ES

1. To conduct a fully powered RCT of Game Changers to test intervention effects on the primary outcomes of increased HIV testing, reduced condomless sex, and decreased enacted HIV stigma among social network members of participating PLWH.
2. To test intervention effects on the secondary outcomes of reduced internalized HIV stigma, increased HIV serostatus disclosure, and increased viral load suppression among participating PLWH, and PrEP uptake among their social network members.
3. To examine whether increased HIV prevention advocacy by PLWH mediates intervention effects on their social network members’ increased HIV testing and condom use, and whether increased HIV disclosure by PLWH mediates intervention effects on social network members’ reduced HIV stigma.
4. To conduct a cost-effectiveness analysis of the intervention.
We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to a no-intervention control
Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenna Amlani Nahid
ID:
PATHWAYS FOR AGILE IMPLEMENTATION: IDENTIFYING THE ACTIVE ELEMENTS OF RAISING VOICES’ GOOD SCHOOL TOOLKIT
REFNo: SS1060ES

to elicit feedback from stakeholders on the program and specific activities to improve the GST ,to understand which aspects of the GST most important for changing relationships within schools and ultimately reducing violence against children ,
 Canada 2021-11-29 2024-11-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Social-spatial networks and Tuberculosis Infection in Children and Youth in Rural Uganda (SONET)
REFNo: HS1844ES

General Objective
To characterize, on a population-level, where and from which social network youth acquire TB infections and to assess variations throughout stages in the early life-course (early childhood: 1-5 years; school-age: 6-11 years; adolescence: 12-18 years).


Uganda 2021-11-29 2024-11-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arnold Moses  Okello Moses
ID:
Addressing Child Trafficking and Slavery in Uganda (ACTS)
REFNo: SS871ES

1. The Standards of Care (SOC) workstream seeks to develop evidence-based nationwide standards of care for survivors and victims of trafficking and slavery. This will involve a desk-based evidence review, online surveys, workshops with the staff of civil society organisations, and analysis of survivor workshop and monitoring and evaluation data collected by project lead Hope for Justice.
2. The Network Strengthening (NSing) component seeks to engage key stakeholders to strengthen internal technical capacity for the Coalition against Trafficking in Persons in Uganda (CATIPU). The aim of this workstream is to increase the capacity of this network of counter-trafficking civil society organisations to improve prevention, protection prosecution and partnership outcomes and capacity for increased collaboration with wider government structures. Therefore, the Unit of Analysis is the network (see Section 12, page 8 below for more detail).

 Uganda 2021-11-26 2024-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
 Analysis of formal and informal institutions of socializing places and their role in shaping vulnerability to HIV: a case of young people (15-24 years) working in socializing places in Uganda
REFNo: HS1536ES

This study aims to analyze formal and informal institutions of socializing places and their role in shaping vulnerability to HIV using a case of YPSP in Uganda. The specific objectives are:
1. To profile socializing places in Uganda and the young people who work in such places
2. To explore the formal and informal institutions of socializing places and their influence on HIV risk and vulnerability of YPSP
3. To determine how YPSP navigate workplace rules and procedures that expose them to HIV risk and vulnerability
4. To explore compliance gaps of the formal and informal institutions of socializing places with the existing laws and opportunities for reducing youth vulnerability to HIV in socializing places

 Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
 PURPOSE 1: GS-US-412-5624/ A Phase 3, Double-Blinded, Multicenter, Randomized Study to Evaluate Safety and Efficacy of Twice Yearly Long-Acting Subcutaneous Lenacapavir, and Daily Oral Emtricitabine/Tenofovir Alafenamide for Pre-Exposure Prophylaxis in Adolescent Girls and Young Women at Risk of HIV Infection. Version 2.0, dated 10 March 2021.
REFNo: HS1920ES

1. Primary Objectives i) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection. 2. Secondary Objectives/ end points i) To compare the efficacy of LEN with F/TDF for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection in participants adherent to LEN. iii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection in participants adherent to F/TAF. iv) To compare the efficacy of F/TAF with F/TDF for HIV PrEP in AGYW at risk of HIV infection. v) To evaluate the safety and tolerability of LEN, F/TAF, and F/TDF for HIV PrEP in AGYW at risk of HIV infection. vi) To evaluate the safety and tolerability of LEN and F/TAF for HIV PrEP in AGYW ≥ 16 to < 18 years of age who have sex with male partners and are at risk for HIV infection. 3. Exploratory objectives i) To assess the adherence rate to LEN as assessed by on-time LEN injection ii) To assess LEN plasma levels iii) To assess the adherence rate to F/TAF and F/TDF using intracellular TFV-DP levels in DBS. iv) To evaluate the acceptability of a once every 26 weeks LEN injection for HIV PrEP in AGYW at risk of HIV infection. v) To assess LEN plasma levels during pregnancy. vi) To explore concentrations of hormonal contraceptives in LEN participants.
Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Clinical Trial Non-degree Award
Julie Teichroeb Annette
ID:
Social decision-making in Angolan colobus (Colobus angolensis ruwenzorii) and vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo
REFNo: NS131ES

Understanding the effects of social constraints on group size and composition, movements, and foraging decisions.
 Canada 2021-11-24 2024-11-24 Natural Sciences Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
 Enhancing immunity to malaria in young children with effective chemoprevention
REFNo: HS1763ES

To compare the incidence of malaria from 4 weeks to 4 years of age among children born to mothers randomized to receive intermittent preventative therapy in pregnancy (IPTp) with monthly sulfadoxine pyrimethamine (SP) alone, monthly DP alone, or both monthly SP+DP.

To compare the incidence of malaria from 2-4 years of age among children randomized to receive IPT in childhood (IPTc) with monthly DP from 8 weeks to 1 year of age vs. monthly DP from 8 weeks to 2 year of age vs. no IPTc.

To compare innate and adaptive effector and regulatory responses between children randomized to different IPT arms.

Uganda 2021-11-24 2024-11-24 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Viga Emmanuel
ID:
MORAL AND SOCIAL DIMENSIONS OF ACCOUNTABILITY IN CIVIC HUMANITARIANISM: RELATIONAL AID AMONGST SOUTH SUDANESE REFUGEES IN UGANDA
REFNo: SS832ES

This research will majorly attempt to answer the question How is accountability of relational aid in civic humanitarianism conceptualized and managed in protracted crisis. This will be achieved by answering the following sub questions:- 1. What differentiates civic humanitarianism from mainstream humanitarian actors? 2. What is relational aid within civic humanitarianism? and how is accountability understood within the concept of relational aid? 3. What are the accountability practices in civic humanitarian aid? 4- How do different accountability forms influence aid delivery?
Uganda 2021-11-23 2024-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
DAN NYEHANGANE
ID:
CYCLOTIDES FROM MEDICINAL PLANTS OF UGANDA: SELECTED SOURCES, ANTIBACTERIAL ACTIVITY, AND CYTOTOXICITY
REFNo: NS258ES

Primary Objective: To identify cyclotides from selected medicinal plants in Uganda and establish their antibacterial activity and cytotoxicity, in order to provide a basis for their medical application in Uganda.

Specific Objectives
1.To determine the presence and quantities of cyclotides in different parts of selected medicinal plant species from selected families reported to express cyclotides and are used to treat bacterial infections in Uganda.
2.To characterize the activity of cyclotides from Ugandan plants in relation to sequence, size and structure
3.To determine antibacterial activities of cyclotides isolated from the different plant species stratified by the plant part extracted and season of harvesting the plant.
4.To determine the cytotoxic effect of the most active antibacterial cyclotide on mammalian cells
5.To determine the synergistic activity of the most active cyclotides against bacterial strains by using combinations of cyclotides from different plant species
6.To establish the anti-biofilm and immunomodulatory activity of the most active anti-bacterial cyclotides



 Uganda 2021-11-23 2024-11-23 Natural Sciences Non-Clinical Trial Degree Award
Brenda McCollum
ID:
Muslims and Islam in Buganda, ca. 1900 - 1962
REFNo: SS950ES

I seek to examine the Muslim experience of colonialism in the Kingdom of Buganda.
USA 2021-11-23 2024-11-23 Social Science and Humanities Non-Clinical Trial Degree Award
Rebecca Nalwanga Nalwanga
ID:
Exploring the Social and Institutional Dimensions of Disability in Primary Education: The Case of Inclusive Development in Uganda
REFNo: SS985ES

This research project aims to better understand the relationship between social development and disability in low-income countries. To achieve this objective, the research project will focus on how the experiences and positionality of primary school learners with a disability intersect with social development, education and democracy, and how these intersections can inform policy and practices to advance social, economic and political development in a low-income country such as Uganda.
 Uganda 2021-11-22 2024-11-22 Social Science and Humanities Non-Clinical Trial Degree Award
Faith Masette Bisikwa
ID:
Exploring Classroom Assessment Practices and its Impact on Preservice Teachers’ self-efficacy in a selected Primary Teachers college, Uganda
REFNo: SS993ES

I used questions instead of objectives
Main Question; How do tutors’ classroom assessment practices impact preservice teacher’s self-efficacy?
Subsidiary questions;
1.What are the common classroom assessment practices in Ugandan Primary teachers’ colleges?

2.How is classroom assessment, practiced in this PTC?

3.What is the relationship between assessment practices and preservice teacher’s self-efficacy?
4.How best can classroom assessment practices be done in PTCs to improve Preservice teachers’ self-efficacy?


 Uganda 2021-11-22 2024-11-22 Social Science and Humanities Non-Clinical Trial Degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 ACTIV-2/A5401: Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID)
REFNo: HS1813ES

1.1 Co-Primary Objectives 1.1.1 Phases II and III: To evaluate safety of the investigational agent. 1.1.2 Phase II: To determine efficacy of the investigational agent to reduce the duration of COVID-19 symptoms through study day 28. 1.1.3 Phase II: To determine the efficacy of the investigational agent to increase the proportion of participants with nasopharyngeal (NP) SARS-CoV-2 RNA below the lower limit of quantification (LLoQ) at study days 3, 7, and 14. 1.1.4 Phase III: To determine if the investigational agent will prevent the composite endpoint of hospitalization due to any cause or death due to any cause through study day 28. Hospitalization is defined as ≥24 hours of acute care, in a hospital or similar acute care facility, including Emergency Rooms or temporary facilities instituted to address medical needs of those with severe COVID-19 during the COVID-19 pandemic. 1.2 Secondary Objectives 1.2.1 Phases II and III: To determine whether the investigational agent reduces a COVID-19 Severity Ranking scale based on COVID-19-associated symptom burden (severity and duration), hospitalization, and death, through study day 28. 1.2.2 Phase II and III: To determine whether the investigational agent reduces the progression of COVID-19-associated symptoms. 1.2.3 Phase II and III: To determine if the investigational agent reduces levels of SARS-CoV-2 RNA in NP swabs. 1.2.4 Phase III: To determine the efficacy of the investigational agent to increase the proportion of participants with NP SARS-CoV-2 RNA below the LLoQ at study day 3. 1.2.5 Phase II: To determine the pharmacokinetics of the investigational agent. 1.2.6 Phase II: To determine efficacy of the investigational agent to obtain pulse oximetry measurement of ≥96% through day 28. 1.2.7 Phase III: To determine if the investigational agent will prevent the composite endpoint of hospitalization due to any cause or death due to any cause through study week 72. 1.2.8 Phase III: To evaluate if the investigational agent reduces the time to sustained symptom resolution through study day 28.
Uganda 2021-11-22 2024-11-22 Medical and Health Sciences Clinical Trial Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 A Phase 2, Open-label, Single-arm, Multicentre Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Efficacy of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to less than 12 years) who are Virologically Suppressed (TMC278HTX2002)
REFNo: HS1815ES


Primary Endpoints
• Area under the plasma concentration-time curve from the time of administration up to 24 hours post-dose of RPV, as derived from the intensive PK assessments.
• Incidence of grade 3/4 AEs, SAEs, HIV-related events (including acquired immune deficiency syndrome [AIDS]-defining illnesses and Stage-3-defining Opportunistic Illnesses in HIV Infection), and AEs leading to discontinuation of study intervention through 24 weeks of study treatment.

Secondary Endpoint
• Incidence and severity of AEs/HIV-related events and their relatedness to RPV through 24 and 48 weeks of study treatment.
• Change from baseline Movement.
• Viral genotype at the time of virologic failure through 24 and 48 weeks of study treatment.
• Treatment adherence, as assessed by the Pediatric European Network for the Treatment of AIDS (PENTA) adherence questionnaire and by study intervention accountability, through 24 and 48 weeks of study treatment.

 Uganda 2021-11-22 2024-11-22 Medical and Health Sciences Clinical Trial Non-degree Award
Jerome  Kabakyenga Kahuma
ID: UNCST-2021-R013729
 The A-Lite vein locator: “a non-invasive assistive medical device designed to improve vein visibility among patients requiring intravenous therapy.”
REFNo: HS1547ES

Main Objective
1. To assess the efficacy, safety and impact of using an assistive medical device to aid vein visibility among patients requiring intravenous therapy.

Specific Objectives
1. To assess the safety and efficacy of the A-Lite vein locator among 10 adults in Uganda.

2. To investigate non-inferiority by assessing the performance of the A-Lite vein locator with respect to the existing standard of care among 48 adolescents in Uganda.

3. To determine the effectiveness of using the A-Lite vein locator for improving vein visibility among 156 children requiring intravenous cannulation in Uganda.
 Uganda 2021-11-19 2024-11-19 Medical and Health Sciences Clinical Trial Non-degree Award
Clare Tanton Tanton
ID:
Taking the Good School Toolkit to scale
REFNo: SS1035ES

The aim of the project is to determine the feasibility and acceptability of using Regional Resource Persons to deliver the Good Schools Toolkit in primary and secondary schools in Uganda and to relate markers of implementation to intermediate outcomes in teachers.
The specific objectives are:
1. To determine whether implementation of the Good Schools Toolkit through Regional Resource Persons can be done with fidelity and whether it is associated with attitudes towards violence against children and markers of school operating culture among teachers.
2. To understand Teacher Protagonists’ motivations, their perceptions of their role and how these evolve during intervention implementation. To understand Teacher Protagonists’ experiences and opinions of intervention mode of delivery and the support they receive from Regional Resource Persons and school administration, and their views on the main successes and challenges of this approach.
3. To understand the experiences of Regional Resource Persons in supporting schools and at different stages of intervention implementation. To understand Regional Resource Persons’ perceptions of the main successes and challenges they face during intervention implementation and how these challenges might be overcome.
4. To explore how the attitudes and behaviours of the Regional Resource Persons evolve following Good Schools Toolkit training and during their role supporting schools, and how this correlates with their performance.
5. To understand teachers’ experiences returning to school after prolonged COVID-related closures

 UK 2021-11-19 2024-11-19 Social Science and Humanities Non-Clinical Trial Non-degree Award
ANGELLA MUSIIMENTA
ID: UNCST-2021-R013297
 My Mobile Wallet: An Intervention to Support Access to Tuberculosis Care and medication Adherence in Rural Uganda
REFNo: HS1688ES

Assess the refined My Mobile Wallet intervention for larger scale feasibility, acceptability, and impact on TB treatment adherence and clinical outcomes. We will randomize 162 newly diagnosed TB patients (1:1:1) to SMS texts + incentives Arm A, SMS texts only B, and control Arm C (standard clinic-based TB care); follow-up will be the 6 month-treatment period. Feasibility and acceptability will be assessed per above. Impact will be based on electronically monitored medication adherence (primary), as well as treatment completion, clinic attendance, cure, and mortality (secondary).,Refine the My Mobile Wallet intervention. We will adapt the intervention to address any feasibility and accessibility issues raised in R21 findings. We will then pilot test the refined version of the intervention in 10 TB patients over two months of treatment to ensure optimal functionality. ,Assess the initial feasibility and acceptability of My Mobile Wallet. Forty patients with newly diagnosed TB will use My Mobile Wallet over their 6-month course of treatment. Feasibility will be assessed by appropriate receipt of the cash transfers and SMS texts, and intervention functionality. Acceptability will be assessed using System Usability Scale [53] and interviews based on the Unified Theory of Acceptance and Use of Technology [54].,Determine the optimal design and develop My Mobile Wallet as an intervention to support TB medication adherence. Through client-centered approaches, we will iteratively conduct focus group discussions with up to 30 TB patients to develop an optimal My Mobile Wallet intervention.,
 Uganda 2021-11-19 2024-11-19 Medical and Health Sciences Clinical Trial Non-degree Award
Noeline Nakasujja
ID: UNCST-2019-R001428
 The impact of the COVID-19 pandemic and its response on the mental health of people with pre-existing mental conditions in Uganda.
REFNo: HS1781ES

5. To explore the experiences and views of people with SMI, their families/caretakers and mental health clinicians regarding the MMHC,4. To assess the effectiveness of an outreach mobile mental health clinic (MMHC)7 initiative to mitigate the care and messaging gap for people with SMI during the Covid-19 pandemic and its response.,3. To explore the experiences and viewsof people with SMI and their families/caretakers regarding COVID -19 and its response ,2. To assess the effect of COVID -19 and its response on access to care for people with SMI ,1. To assess the effect of COVID -19 and its response on the mental health of people with SMI ,
 Uganda 2021-11-18 2024-11-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jack Rugasira
ID:
GREEN SUPPLY CHAIN PRACTICES AND ENVIRONMENTAL SUSTAINABILITY: A CASE OF SELECTED UGANDA MANUFACTURERS ASSOCIATION ENTITIES IN KAMPALA
REFNo: NS308ES

i. To determine the relationship between green sourcing and resource use efficiency in Kampala district.
ii. To determine the impact of green manufacturing on ecological balance in Kampala district.
iii. To assess the relationship between green transportation and availability of clean air and water in Kampala district.
iv. To determine the relationship between reverse logistics and wetland management in Kampala district

 Uganda 2021-11-18 2024-11-18 Natural Sciences Non-Clinical Trial Degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 The Relation Between Mean Glucose and HbA1c in Ugandan Children and Youth with T1D: An Observational Study
REFNo: HS606ES

PRIMARY OBJECTIVES
1. To determine the relation between laboratory-measured HbA1c and mean glucose as measured by continuous glucose monitoring (assessed over 10-14 days per sensor period).
2. To determine the consistency of the relationship between laboratory- measured HBA1C and the mean glucose using multiple measurements in Ugandan Children and youth.
3. To determine the relation between laboratory-measured HbA1c and factors known to impact red blood cell survival.
SECONDARY OBJECTIVE
To determine the relation between point-of-care HbA1c and mean glucose in this population.

 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-degree Award
Catherine Atuhaire
ID: UNCST-2021-R013090
 A multi-morbidity study of diabetes mellitus, hypertension and Postpartum depression among postnatal mothers (MMDHAPPD) in Mbarara city, Uganda
REFNo: HS1836ES

To explore the challenges and coping strategies of mothers suffering from these multiple morbidities in Mbarara city, Uganda,To compare the serum cortisol levels of mothers diagnosed with and without postpartum depression,To determine the prevalence of hypertension among mothers diagnosed with postpartum depression in Mbarara city, Uganda ,To determine the prevalence of diabetes among mothers diagnosed with postpartum depression in Mbarara city, Uganda ,To assess the association between postpartum depression and either diabetes, hypertension or both among mothers in Mbarara city, Uganda,To determine the prevalence of postpartum depression based on the DSM-5 among mothers in Mbarara city, Uganda,To investigate the association between PPD and diabetes / hypertension or both and to explore the challenges and coping mechanisms experienced by these mothers suffering from these multiple morbidities in Mbarara city, Uganda,
 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Leevan Tibaijuka
ID: UNCST-2021-R012986
 Maternal comorbidities in pregnancy and post-delivery at Mbarara Regional Referral Hospital
REFNo: HS1734ES

3) To adapt a mobile application and assess the feasibility and acceptability of a pilot implementation of an intervention of sending appointments reminders and health education tips inform of SMS and pre-recorded voice messages to post-delivery women with co-morbidities to improve their compliance to follow-up appointments at MRRH. ,2) To compare the incidence of adverse maternal-fetal outcomes in women with and without medical co-morbidities and determine the predictors of adverse maternal-fetal outcomes among women admitted for delivery at MRRH. ,1) To determine the prevalence of and modifiable risk factors associated with medical comorbidities among pregnant and post-delivery women at MRRH.,To explore medical co-morbidities among pregnant and post-delivery women at Mbarara Regional Referral Hospital (MRRH),
 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Janet SEELEY
ID:
African Prostate Cancer - Disparities in Outcomes in Uganda (APC-DOUG)
REFNo: HS1790ES

Aim/goal of study (General Objective)
The African Prostate Cancer - Disparities in Outcomes in Uganda (APC-DOUG) study aims to evaluate the health system, socioeconomic and clinical factors that impact public hospitals across Uganda to deliver affordable interventions that improve and reduce inequalities in prostate cancer outcomes.

1.6 Specific objectives
1. To evaluate the current structure and organisation of clinical care for prostate cancer
2. To understand the socio-economic, cultural and geographic barriers to accessing care

UK 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ALLAN BAGUMA
ID: UNCST-2021-R012022
 Effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV KCCA health facility in Kampala.
REFNo: HS1879ES

General Objective
To determine the effect of Covid-19 pandemic and national lockdown on utilization of childhood immunization services at Kisenyi health centre IV health facility in Kampala.
Specific Objectives
1. To determine the pre-lockdown childhood immunization coverage at Kisenyi health facility in Kampala.
2. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala during the national lockdown.
3. To assess the barriers and facilitators of childhood immunization at Kisenyi health centre IV facility in Kampala during the covid 19 pandemic.
4. To determine the coverage of child hood immunization at Kisenyi health facility in Kampala post the national lockdown

 Uganda 2021-11-17 2024-11-17 Medical and Health Sciences Non-Clinical Trial Degree Award
Ritah Kigonya
ID:
Enhancing Livelihood Outcomes in Biodiversity offset Schemes in Uganda’s Oil and Gas Industry’s CSR Strategies
REFNo: SS332ES

The overall objective of the study is to enhance incorporation of people’s use and cultural values of biodiversity during the design and implementation of biodiversity offsets. The specific objects include; Objective 1: Mapping the extent of biodiversity offset projects and their effects on community livelihoods. Objective 2; Analyze the extent to which biodiversity-based livelihood compensation schemes (social offset schemes) attain their desire objectives. Objective 3; Use lessons from biodiversity-based compensation schemes to ascertain who to compensate, what to compensate and how to compensate them during implementation of biodiversity-based livelihoods
Uganda 2021-11-16 2024-11-16 Social Science and Humanities Non-Clinical Trial Degree Award
JOSAPHAT KAYOGOZA BYAMUGISHA
ID: UNCST-2019-R001680
 REPRODUCTIVE TRACT INFECTIONS AMONGST STUDENTS: ADDRESSING THE CHALLENGE AT MAKERERE UNIVERSITY
REFNo: HS1810ES

To determine the prevalence of RTIs among Makerere University students,To assess the Reproductive Tract Infections (RTIs) related knowledge, attitude and practices (KAP) of the Makerere University population.,To address the challenge of Reproductive Tract Infections amongst students by establishing the prevalence, knowledge of students towards RTIs and reducing the gap through use of youth friendly approaches.,
 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
RACHAEL KULWENZA
ID:
EXPLORING THE TEACHING OF READING IN LOWER PRIMARY CLASSES IN KOCHEKA SUBCOUNTY, UGANDA. A CASE OF ONE GOVERNMENT PRIMARY SCHOOL.
REFNo: SS987ES

•To find out what teaching and learning approaches do teachers use to teach reading in the lower primary level. •To investigate how do the approaches that teachers use in teaching reading in lower primary levels impact the development of the reading competences of the children?
•To find out what opportunities and challenges exist when teaching reading to learners in the lower primary level?

 Uganda 2021-11-15 2024-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
RICHARD EDEMA BAZIL
ID:
Investigating how teachers use mother tongue as a medium of instruction for lower primary mathematics
REFNo: SS1013ES

The objectives of the study are to establish: -
1. How the teachers are providing for the use of mother tongue as a medium of instruction during preparation for teaching and learning lower primary mathematics?
2. How the teachers are using mother tongue as a medium of instruction during teaching and learning processes of mathematics in P1 to P3?
3. The opportunities presented by the use of mother tongue in the teaching and learning of mathematics in P1 to P3?
4. The challenges the teachers face in the use of Mother tongue as a medium of instruction for mathematics in lower primary classless?

Uganda 2021-11-15 2024-11-15 Social Science and Humanities Non-Clinical Trial Degree Award
Arthur Bagonza
ID:
EFFECT OF COVID-19 ON PAEDIATRIC FEVER TREATMENT AMONG REGISTERED PRIVATE DRUG SELLERS IN EAST-CENTRAL UGANDA
REFNo: HS1729ES

1. To determine the effect of lock-down due to COVID-19 on treatment of children less than five years presenting with malaria,diarrhoea and pneumonia symptoms at registered private drug shops in Luuka district, East Central Uganda.

2. To explore perceptions of drug sellers and key stakeholders regarding treatment of children less than five years presenting with malaria,diarrhoea and pneumonia symptoms at registered private drug shops in Luuka district,East Central Uganda.

 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fatumo  Segun Adeyemi
ID:
Causal Relationship between Cardiometabolic traits and Chronic Kidney Disease in African Population.
REFNo: HS1730ES

1. To Identify genetic determinants of kidney function in continental Africa"
2. To investigate the predictive utility of Polygenic Risk Scores for Chronic Kidney disease in Africans.
3. To assess the causal effect of kidney function on cardiometabolic diseases using Mendelian Randomisation Approach.

 UK 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Geoffrey Beyihayo Akiiki
ID:
Native Chicken Project
REFNo: A154ES

To establish genetic markers associated with economic traits among indigenous chicken eco-types,To establish genetic and phenotypic parameter estimates for economic traits among indigenous chicken eco-types,To assess the genetic diversity of indigenous chickens eco-types based on mitochondrial DNA (mtDNA),To characterize indigenous chicken based on qualitative and quantitative phenotypic traits ,To characterize and identify genetic markers of egg and growth traits for selection of highly productive indigenous multipurpose chickens ,
 Uganda 2021-11-15 2024-11-15 Agricultural Sciences Non-Clinical Trial Degree Award
David Guwatudde
ID: UNCST-2021-R008522
 The Uganda Non-Communicable Diseases (NCD) Risk Factor Mobile Phone Survey - 2021
REFNo: HS1738ES

1.Evaluate the efficacy (as measured by the response rate), of conducting a mobile phone survey to collect data on the common NCD risk factors

2.Collect data on specific NCD disease conditions, and the self-reported NCD risk factors to support monitoring and evaluation of programs and policies in Uganda.

3.Generate comparable data from mobile phone surveys within Uganda over time.

4.Provide data to the Ministry of Health and other relevant ministries, and make recommendations on developing, improving, and enhancing prevention and response strategies to address NCDs and NCD associated disabilities in Uganda.
 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalyesubula Edward
ID: UNCST-2021-R012991
 The prevalence of oral diseases and their associated factors in children and adolescents attending the diabetes clinic at Mulago
REFNo: HS1799ES

1. To determine the prevalence of dental caries among children and adolescents attending the diabetes clinic at Mulago.
2. To determine the prevalence of periodontal diseases among children and adolescents attending the diabetes clinic at Mulago.
3. To determine the associated risk factors for dental caries among children and adolescents attending the diabetes clinic at Mulago.
4. To determine the associated risk factors for periodontal diseases among children and adolescents attending the diabetes clinic at Mulago
 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Adeodata Rukyalekere Kekitiinwa
ID: UNCST-2019-R000799
 BREATHER Plus: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir- based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub-Saharan Africa, Version 2.0, Dated 18-Mar-2020; ISRCTN #: 85058577
REFNo: HS1822ES

Major Objective: A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir-based triple ART in virologically suppressed HIV-infected adolescents aged 12 to 19 years of age in sub- Saharan Africa
Specific Objectives
To evaluate an innovative and contemporary ART strategy in HIV-infected adolescents to provide choice for young people facing life-long treatment. Output from this RCT will provide evidence on efficacy, safety and acceptability of a novel treatment approach in HIV-infected adolescents in sub-Saharan Africa
To evaluate the virological efficacy, safety, acceptability and Quality of Life of DTG-based Short-cycle Therapy with weekends off compared with Continuous Therapy with a DTG- based ART regimen
To optimize treatment for HIV-infected adolescents in sub-Saharan Africa

 Uganda 2021-11-15 2024-11-15 Medical and Health Sciences Clinical Trial Non-degree Award
Mvuyo Sikhondze Maqhawe
ID:
DIABETIC FOOT ULCERS: SURGICAL CHARACTERISTICS, TREATMENT MODALITIES AND SHORT-TERM TREATMENT OUTCOMES AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1857ES

General Objective
To describe the surgical characteristics, treatment modalities and short-term treatment outcomes of diabetic foot ulcers at Mbarara Regional Referral Hospital.

Specific Objectives
1. To describe the surgical characteristics of diabetic foot ulcers observed at Mbarara Regional Referral Hospital.
2. To describe the treatment modalities of diabetic foot ulcers at Mbarara Regional Referral Hospital.
3. To document the short-term treatment outcomes of patients with diabetic foot ulcers at Mbarara Regional Referral Hospital.
 Eswatini 2021-11-15 2024-11-15 Medical and Health Sciences Non-Clinical Trial Degree Award
Sabine, Willemina, Johanna Luning
ID:
Gold Matters: Transformations to Sustainability in Artisanal and Small Scale Gold Mining in Uganda
REFNo: SS716ES

1. To consider whether a transformative approach toward sustainability can arise in Artisanal and Small Scale Gold Mining (ASGM).
2. To explore new notions of sustainability and transformations.
3. To contribute to a better understanding of the dynamic, heterogeneous reality of ASGM.
 Netherlands 2021-11-11 2024-11-11 Social Science and Humanities Degree Award
Jessica Perkins M
ID: UNCST-2021-R013564
 Perceptions of Social Norms and Personal Propensity to Engage in HIV Testing: A Mixed Methods Study and Intervention in Rural Uganda
REFNo: SS812ES

We propose a study to assess norms and perceptions about HIV prevention and related topics. This includes assessing village norms (i.e., the behaviours or attitudes of more than 50% of the adult population), perceived norms, how people form their perceptions, which social reference groups are the most meaningful, and the difference between actual norms and individuals’ perceptions of what most others do or believe. We will also examine whether perceptions are associated with personal behaviours and attitudes. Project 1 Aim: To engage in secondary analysis of quantitative data about perceived social norms and actual population norms around HIV prevention behaviours and related topics across different social reference groups. Aim 1: We will assess the prevalence of perceived and actual behavioural norms. We will do this both at the village-level and across various sociodemographic and health indicators. We will consider a behaviour the village norm if it is reported by more than 50% of adults. Aim 2: Because the parent study includes nearly all adults living in Nyakabare Parish, we can compare the actual village norm (assessed in Aim 1) to perceptions of the village norm. The parent study asked participants about their perceptions of what most other adults in the village do or think. Aim 3: Using the self-reported behaviours, attitudes, and norm perceptions, we will test whether individuals’ perceptions of what is normative is related to their personal attitudes and behaviours. Project 2 Aim: To use qualitative research methods to understand the nuances of HopeNet participants’ perceptions about local norms and design valid survey questions that elicit perceived social norms about HIV testing within different reference groups. Aim 1: Through in-depth interviews, scenarios related to HIV prevention attitudes and behaviours and perceived norms about salient social reference groups will be discussed. Aim 2: Based on results from Aim 1, survey questions using different ways of assessing norms will be developed to assess perceived social norms around HIV-related prevention behaviours and attitudes among different reference groups. Aim 3: Through cognitive interviews, the content validity of these survey questions to elicit perceptions of social norms about HIV-related attitudes and behaviours among specific social reference groups will improve.
USA 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
SIMON EWASU -
ID:
EXPLORING THE INFLUENCE OF SCHOOL LEADERSHIP ON STUDENTS’ ACADEMIC PERFORMANCE: A COMPARATIVE STUDY OF TWO PRIMARY SCHOOLS’ IN OMODOI SUB-COUNTY-UGANDA
REFNo: SS980ES

1. To explore how school leadership influences learners’ academic performance in schools’?
2. What school leaders do to improve on the students’ academic performance in schools
3. To find out the teachers’ and students’ perceptions on the school leadership on students’ academic performance.
4. To find out the strategies school leaders employ to support their own teams to improve on the learner’s academic performance?

 Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
 Modular Wireless Patient Monitoring System (MWPMS) Among a Subset of Patients Enrolled in an Observational Study of Sepsis in Uganda
REFNo: HS1687ES

At the FPRRH study site in Uganda, investigators will incorporate an assessment of the utility of a novel Modular Wireless Patient Monitoring System (MWPMS), supported by personalized data analytics, to provide a continuous, objective measure of physiological status in patients with sepsis. We aim to demonstrate correlation with manually collected vital signs. We also aim to identify specific features or combinations of features measured via MWPMS that predict 28-day mortality. This is a sub-study which will be incorporated in the main protocol observing sepsis patients hospitalized in Uganda
 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Owenda Omulo Charles
ID:
The socioeconomic impact of floriculture industry on the livelihoods of communities hosting flower farms in Uganda
REFNo: SS1004ES

Main Objective
The main aim of this study is to examine the socio-economic impact of flower farm projects on the livelihoods of their host communities.

Specific Objectives
Specifically, the study will have the following objectives and associated research questions;
To find out how the financial reward (wages) has contributed in changing the livelihood of flower farm workers from the time they joined the flower farm.

To examine the extent by which flower farms have contributed to the improvement of the basic infrastructure and producer goods needed to support people’s livelihoods in their host communities.
To find out how the farms are prepared to overcome the challenges of environmental degradation and human abuse (as witnessed in workers’ exposure to hazardous agrochemicals in other countries) in order to improve people’s livelihoods.

 Kenya 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Christine Watera
ID:
Cyclical Acquired HIV Drug Resistance Surveillance: Focusing on Dolutegravir in Uganda
REFNo: HS1774ES

a) To estimate the prevalence of acquired drug resistance (ADR) among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
• Adolescents and Adults ≥ 15 years
• Children < 15 years old
b) To describe the patterns of ADR among individuals receiving DTG for at least 12 months with VL non suppression, by age sub-groups
c) To describe the prevalence and pattern of ADR among individuals receiving DTG with VL non-suppression by sub-population characteristics (e.g., sex, duration on antiretroviral therapy (ART), line of ART, pregnant and breast feeding, etc.):
d) To compare the proportion of individuals with HIVDR pre- and post-intensive adherence counselling (IAC)

 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Birungi Mwebaze
ID:
Decision Making Dynamics in the use of Female Sterilisation by Women Living with HIV in Uganda
REFNo: SS1044ES

To explore the personal factors that influence the agency to implement decisions regarding use of sterilisation by women living with HIV in Uganda, To describe the micro-level social contexts that influence the decisions of Women Living with HIV on the sue of female sterilisation by as a method of contraception, To assess the macro- level cultural contexts that influence the decisions of Women Living with HIV to use sterilisation.
 Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Degree Award
Agata Staniewicz
ID: UNCST-2021-R012236
 Interspecific competition for acoustic space in birds
REFNo: NS302ES

Determine whether and how various species of birds compete with each other and with other animals for acoustic space.
 Poland 2021-11-11 2024-11-11 Natural Sciences Non-Clinical Trial Non-degree Award
Karlmax Rutaro
ID: UNCST-2021-R012720
 Value chain hygiene practices and microbial contamination of street and market vended ready-to-eat grasshoppers, Ruspolia spp. in Uganda
REFNo: HS1869ES

The overall aim of the study is to document the value chain hygiene practices and microbial contamination of street-hawked and market-vended RTE grasshoppers, Ruspolia spp. in Uganda.

The specific objectives are:
i. To document the hygiene practices along the RTE grasshopper value chain, including the personnel involved, in Kampala City and Masaka Town in Uganda.
ii. To determine the level of microbial contamination in the RTE grasshoppers at different stages of the value chain in Kampala City and Masaka Town in Uganda.
iii. To establish the relationship between RTE grasshopper value chain hygiene practices and the microbial contamination.

 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allen Namagembe Sekitoleko
ID: UNCST-2019-R000214
 Injecto Easyject contraceptive self-injection use in Uganda
REFNo: HS1851ES

1.To assess ease of use of the Easyject device, from the perspective of clients (self-administration) and providers (provider administration), relative to the Uniject
2.To identify challenging steps when learning to use the Easyject
3.To evaluate overall acceptability of Easyject injection device for clients, providers and stakeholders
 Uganda 2021-11-11 2024-11-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jane Namukobe
ID:
Bioactivity and chemical investigation of natural products composition from selected plants used in skin infections and protection.
REFNo: NS306ES


i. To determine the sun protection, antioxidant and antibacterial activities of extracts from selected plants used in skin infection and protection
ii. To determine the dermal and oral toxicity of extracts
iii. To isolate and elucidate the structures of bioactive compounds
iv. To determine the sun protection factor, antioxidant and antibacterial activities of isolated compounds
v. To prepare synthetic derivatives of some interesting isolated compounds

 Uganda 2021-11-11 2024-11-11 Natural Sciences Non-Clinical Trial Non-degree Award
Herbert Muyinda
ID: UNCST-2019-R000373
 A comparative study of COVID-19 tests in the DRC and Uganda: Situating the knowns and unknowns in the COVID-19 pandemic
REFNo: SS1088ES

To study the consequences of unknowing on people’s health-seeking behavior during the COVID-19 pandemic.,To examine COVID-19 testing as a technology of knowing, and the responses [to COVID-19 pandemic] made visible by testing,To explore how testing—and in particular the absence of testing—shapes both knowing and unknowing in the context of the pandemic. ,To explore how diagnostic tests have been used to devise and implement the COVID-19 response in both countries.,The general objective of this project is to provide an in-depth study of the role of diagnostic tests in relation to the management of COVID-19 pandemic in Uganda.,
 Uganda 2021-11-11 2024-11-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Philip Leonard
ID:
Understanding the current challenges faced by coffee farmers in the Technoserve Farm College
REFNo: A162ES

1) Identify current concerns related to COVID-19.
2) Identify current challenges on farming activities including access to inputs, farms and markets.
3) Understand how coffee farmers are able to access to emergency finance.
4) Identify changes in availability of food.

 Canada 2021-11-11 2024-11-11 Agricultural Sciences Non-Clinical Trial Non-degree Award
Etheldreda Nakimuli-Mpungu
ID: UNCST-2020-R014808
 Promoting Adherence to Anti-retroviral Therapy and Viral suppression among HIV positive Young People in Uganda through Group Support Psychotherapy: Study Protocol for a Pilot Randomized Controlled Trial
REFNo: HS864ES

To pilot measures of cost-effectiveness,To explore whether or not psycho-social factors mediate or modify the effect of GSP on ART adherence and viral suppression among young people attending Kitgum Hospital HIV Clinic .,To assess the feasibility, acceptability and preliminary effectiveness of GSP in promoting ART adherence and viral suppression among young people attending Kitgum Hospital HIV Clinic,To use the qualitative data obtained to modify GSP to suit the needs of young people with HIV,To conduct community-based participatory qualitative research to obtain information on the potential usefulness of group support psychotherapy in improving ART adherence and viral suppression among young people attending Kitgum Hospital HIV Clinic,
 Uganda 2021-11-08 2024-11-08 Medical and Health Sciences Non-degree Award
Charles  Katulamu
ID:
Fertility Behaviors among recent university graduates in Kampala-Uganda.
REFNo: SS997ES

i. To establish relationship, union, and/or marriage patterns among recent university graduates.
ii. To investigate the fertility desires, preferences, and intentions among recent university graduates.
iii. To explore recent university graduates’ knowledge and experiences on contraceptive use and abortion.

Uganda 2021-11-05 2024-11-05 Social Science and Humanities Non-Clinical Trial Degree Award
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