Mohammed Lamorde
ID: UNCST-2019-R001293
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An open-label, randomized, single intravenous dosing study to investigate the effect of fixed dose combinations of tenofovir/lamivudine or atazanavir/ritonavir on the pharmacokinetics of remdesivir in Ugandan healthy volunteers
REFNo: HS654ES
Primary objectives
1. To assess the safety and tolerability of single intravenous doses of remdesivir in adult healthy volunteers
2. To evaluate the intracellular pharmacokinetics of single dose intravenous remdesivir with or without co-administration of oral fixed-dose combination tenofovir/lamivudine with patients serving as their own controls
Secondary objectives
1. To evaluate the difference in plasma and intracellular pharmacokinetics of intravenous remdesivir among healthy volunteers receiving tenofovir/lamivudine versus healthy volunteers receiving tenofovir/lamivudine plus atazanavir/ritonavir tablets.
2. To generate a population pharmacokinetic model to describe inter-individual variability in intracellular pharmacokinetics of remdesivir
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Nigeria |
2020-08-24 |
2023-08-24 |
Medical and Health Sciences |
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Non-degree Award |
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DEUS KAMYA
ID:
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In-vitro activity of mycobacteriophages against Mycobacterium tuberculosis biofilms
REFNo: HS774ES
1. To characterize the lytic activity of mycobacteriophages using Mycobacterium smegmatis mc2155 as host bacterium
2. To determine mycobacteriophage host range on a panel of 50 clinical isolates of Mycobacterium tuberculosis
3. To determine the inhibitory and disruptive effect(s) of mycobacteriophages on Mycobacterium tuberculosis-biofilms
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Uganda |
2020-08-24 |
2023-08-24 |
Medical and Health Sciences |
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Degree Award |
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CATHERINA NAZZIWA
ID:
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Perspectives on Genetic Research and
Curative Therapies for Sickle Cell Disease
REFNo: SS520ES
The main objective of this study is to assess perspectives of diverse sickle cell disease stakeholders in Uganda regarding participation in genetics research and curative therapies for sickle cell disease, and to identify the related key ethical, social and cultural issues.
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Uganda |
2020-08-24 |
2023-08-24 |
Social Science and Humanities |
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Degree Award |
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CATHERINE ABBO
ID:
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Incorporating mental health and psychosocial support in the Ugandan Police Child and Family Protection Department toll free line to address sexual and gender-based violence (SGBV) complaints.
REFNo: HS791ES
1. To explore the understanding of TFLOs regarding MHPSS needs of complainants of SGBV.
2. To develop and implement a mental health and psychosocial support training for 20 TFLOs working in Kampala and Wakiso Districts.
3. To conduct an evaluation of the training programme among the TFLOs.
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Uganda |
2020-08-24 |
2023-08-24 |
Medical and Health Sciences |
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Degree Award |
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Gilbert Habaasa
ID:
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Death registration completeness, gendered Social norms and Behavioural practices affecting death registration in Uganda
REFNo: SS539ES
i. To establish the prevalence of death registration in HDSS sites of Uganda (absolute number of deaths registered).
ii. To find out the level of data quality for death registration in HDSS sites of Uganda
(death registration completeness, timeliness of death registration).
iii. To generate gendered vital statistics using existing death data in HDSS sites of Uganda (Age Specific Mortality Rates, Life expectancy at birth and cause of death by age and gender)
iv. To find out the gendered social norms and behavioral practices that lead to under-registration of deaths in Uganda.
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Uganda |
2020-08-24 |
2023-08-24 |
Social Science and Humanities |
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Non-degree Award |
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Faith Sebuliba Rosemary Kasumba
ID:
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To explore Nursing Students Readiness to Learn in a Technology Enhanced Environment in Degree Completion Programs in Institutions of Higher Education in Uganda
REFNo: HS716ES
i.Describe nursing student self-efficacy of technical competencies that promote, their readiness to learn in technology enhanced environments.
ii.Describe personal attributes associated with nursing students’ readiness to learn in technology enhanced environments.
iii.Determine institutional support that promote nursing students readiness to learn in technology enhanced environments.
iv.Determine nursing students’ perspectives regarding their readiness to learn in a technology enhanced environment.
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Uganda |
2020-08-21 |
2023-08-21 |
Medical and Health Sciences |
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Degree Award |
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Noah Kiwanuka
ID: UNCST-2021-R010125
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Bio ethical Issues in the Use of Mobile Phone Data for Public Health Research in Uganda
REFNo: HS717ES
1. To perform a systematic review of the literature to document the current state-of-evidence on the ethics related to the use of mobile phone CDRs and data from other mobile devices for public health research in Africa. We will search published and unpublished literature to identify what is known and gaps in knowledge about ethics of CDRs.
2. To assess perception, attitudes and concerns of key stakeholders in relation to the utilization of CDRs for public health research in Uganda. We will conduct a mixed- methods study using key informant interviews and focus group discussions and quantitative surveys to gather information about ethical concerns, opinions, and suggestions from a range of selected stakeholders. The stakeholders will include patients, community members, health workers, health researchers, government officials, telecommunication companies, Institutional Review Boards/Ethics Committees, academic faculty, research organizations, ICT regulatory boards among others.
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Uganda |
2020-08-21 |
2023-08-21 |
Medical and Health Sciences |
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Non-degree Award |
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Andrew Mujugira
ID: UNCST-2019-R000871
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Same-Day PrEP Initiation and Sexual Health for Transgender Women
REFNo: HS772ES
1) Evaluate the feasibility and acceptability of same-day F/TAF PrEP initiation among African trans women
2) Characterize F/TAF persistence and test the impact of drug level feedback among African trans women taking PrEP
3) Explore how self-care interventions for sexual health influence HIV/STI prevention choices among African trans women and their sexual partners
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Uganda |
2020-08-21 |
2023-08-21 |
Medical and Health Sciences |
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Non-degree Award |
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Simon Peter Katongole
ID:
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Strengthening health systems for quality health care: case study of misdiagnosis among hospitalized patients in general hospitals in Uganda
REFNo: HS826ES
To examine health system factors associated with misdiagnosis for improving health care quality in general hospitals in Uganda.
Specific objectives
a) To determine the prevalence of misdiagnosis for patients admitted to general hospitals in Uganda.
b) To examine association between health system and individual-related predictors with misdiagnosis in general hospitals in Uganda.
c) To explore health workers’ perspectives of the predictors of misdiagnosis among admitted patients in general hospitals in Uganda.
d) To assess the financial cost of misdiagnosis among inpatients in hospitals in Uganda.
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Uganda |
2020-08-21 |
2023-08-21 |
Medical and Health Sciences |
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Degree Award |
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Richard Muhindo
ID:
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Fighting COVID-19: Assessment of Health Systems Support for Psychosocial Preparedness and Needs of Health Workers Providing Essential Patient Care in Uganda
REFNo: HS715ES
3. To develop and propose a model for psychosocial and emotional support for healthcare professionals working in contexts of contagious disease outbreaks ,2. To examine health systems institutional capacity to provide psychosocial and emotional support to health professionals providing essential care to people with COVID-19.,1. To describe the psychosocial preparedness and of healthcare professionals providing essential care to people with COVID-19,To assess the health systems’ support for psychosocial preparedness and needs of healthcare professionals providing essential care for people with COVID-19 in Uganda,
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Uganda |
2020-08-20 |
2023-08-20 |
Medical and Health Sciences |
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Non-degree Award |
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