Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,795
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Insight into the Role of the Microbiome in Pulmonary tuberculosis in Kampala, Uganda (MTI-Plus)
REFNo: HS738ES

The overall purpose of this proposal is to determine the composition of the microbiome in pulmonary TB patients in Kampala Uganda, and its relationship with TB treatment response and immune response relative to household healthy contacts without TB and HIV-infection. In context of treatment naïve adult TB patients, we will (1) (a) Examine the relationship between sputum and gut microbiome diversity and disease. (b) Investigate the relationship between sputum and gut microbiome composition and treatment response in patients on first-line TB therapy, and whether dysbiosis resolves in patients who get cured from TB after successfully completing anti-TB therapy. (2). Investigate the relationship between sputum and gut microbiome composition and inflammatory cytokine production capacity.
Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Chioma Adeyemi Njideka
ID:
Phytochemical and Abortifacient Studies of Commelina benghalensis in Wister Rats
REFNo: SS576ES

The specific objectives of this study are;
a) To profile the phytochemical groups in C. benghalensis L in rats.
b) To determine the acute toxic dose of leaves and stalk extracts of C. benghalensis L in rats.
c) To investigate the abortifacient activities of leaves and stalk extracts of C. benghalensis L in rats.
d) To evaluate the sub-acute effect of the plant extract showing more abortifacient activity in wistar rats.

 Nigeria 2020-11-20 2023-11-20 Social Science and Humanities Degree Award
Barbara Mukasa
ID:
Baseline, Midterm and End of Project Evaluation Protocol for Mildmay Mubende Region
REFNo: SS639ES

(i) Systemize baseline, midterm and end of project evaluations including interim analyses for Mubende region service delivery implementing mechanism supported by CDC Uganda.
(ii) Closely monitor the progress of outputs as measured by Monitoring Evaluation and Reporting (MER) indicators arising from implementation of activities and conduct periodic program evaluations to determine the funded activities will achieve outcomes that ultimately reduce HIV incidence and AIDS

 Uganda 2020-11-20 2023-11-20 Social Science and Humanities Non-degree Award
Paul  Kutyabami
ID: UNCST-2020-R015029
 Assessing the impact of the requirements for dual- licensing guidelines on the number of drug outlets and compliance to regulation
REFNo: HS1048ES

-To determine the trends in the number of pharmacies licensed as both retail and wholesale from 2016 to 2020 in NDA regions
-To establish the level of compliance of pharmacies previously dual-licensed as of 2016 to set requirements of their current license
-To explore the possible factors other than guidelines associated with a decline in the license application for pharmacies that have had dual licensure
-To determine the effect of dual licensing guidelines on access to medicines in underserved areas

 Uganda 2020-11-20 2023-11-20 Medical and Health Sciences Non-degree Award
Winnifred Kansiime Kimara
ID: UNCST-2021-R012131
 Predictors of indoor air quality in Kisenyi-Mugunu a slum settlement in Fort Portal Municipality, Uganda
REFNo: HS695ES

General objective
To assess predictors of indoor air quality so as to promote the health of children under five dwelling in Kisenyi-Mugunu, Fort Portal Municipality.
Specific objectives
1. To determine the level of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
2. To establish the predictors of IAQ in Kisenyi-Mugunu, Fort Portal Municipality.
3. To explore the barriers and facilitators to uptake of healthier household energy options in Kisenyi-Mugunu.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 Characterizing Determinants of Primary KSHV Infection among Children and Adolescents in Uganda
REFNo: HS735ES

1. To determine the incidence and to define the viral, immunologic, and clinical features of primary KSHV infection.
2. To identify the biologic and behavioral risk factors associated with primary KSHV infection.
3. To develop mathematical models that characterize KSHV shedding dynamics and virologic drivers required for transmission.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 Machine Learning and Secondary Data Analyses of the RASHOTS Database to Guide Clinical Decision Making and Predict Patient Prognosis at Kiruddu National Referral Hospital, Uganda
REFNo: HS745ES

The primary project objectives are:
1. To utilise ML methods to estimate the risk of mortality on the ID wards at Kiruddu National Referral Hospitals using the RASHOTS medical database
2. To develop prognosis prediction scores for survival on the ID wards using ML methods on the RASHOTS medical database based on clinical prognostic factors

The secondary project objectives are:
1. To estimate the prevalence of major mortality drivers such as tuberculosis, tetanus using the RASHOTS medical database
2. To create a prognosis prediction protocol for risk of tuberculosis related mortality as a computer application for use by clinicians on ID wards
3. To use the RASHOTS database for quality improvement in clinical care and practice in the department of Internal Medicine

Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Annette Namugaya Mugabe Jane
ID: UNCST-2020-R014795
 TRENDS AND INDICATIONS FOR CAESAREAN SECTION IN MBALE REGIONAL REFERRAL HOSPITAL A CROSS SECTIONAL STUDY
REFNo: HS777ES

General Objective
To determine the trends and indications for caesarean section delivery in MRRH (Eastern Uganda) during the study period (July 2013 to June 2018)

Specific Objectives
1. To determine the trend for caesarean section in MRRH (Eastern Uganda) over the study period
2. To identify the indications for CS delivery in MRRH (Eastern Uganda) over the study period

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Degree Award
Peter Rukundo Milton
ID: UNCST-2020-R014799
 Next Generation Nutrition in Uganda: Enhancing Dietary Intake of Iron and Folic Acid in a Culturally Acceptable Food Product for Pregnant Women to Improve Maternal and Child Outcomes
REFNo: HS828ES

Evaluate the effect of the innovative product on the health outcomes of the infants at birth,Investigate the efficacy of this innovative product to reduce iron and folic acid deficiency in pregnant women.,Develop a culturally acceptable and quality assured iron bio-fortified beans and silverfish pre-cooked instant sauce fortified with iron and folic acid to meet nutritional needs for pregnancy.,
 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Irene Andia Biraro Rebecca
ID: UNCST-2019-R001475
 The Trends in Clinical Presentation and Management of Diseases among Adults attending Kiruddu National Referral Hospital, Kampala: Review of Medical Records.
REFNo: HS1030ES

General objective
To analyse medical records for trends in presentation and management of disease conditions in the in-patient department (IPD) and out-patient department (OPD) at KNRH from 2019 to date.
Specific objectives
I. To describe trends of respiratory disease presentation and clinical management among adult patients presenting to the IPD, medical and general OPD at KNRH during the study period (January to July 2020) compared to the baseline period (January to July 2019)
II. To explore for any collateral effects of the global SARS-CoV-2 pandemic on chronic disease presentation and management at KNRH during the same study period.

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 AN ASSESSMENT OF THE IMPACT OF COVID-19 ON RMNCAH AND HIV SERVICE DELIVERY AND UTILIZATION IN UGANDA
REFNo: HS1084ES

1. To document the response actions for mitigating the impact of COVID-19 on RMNCAH and HIV services at national, sub-national, health facility and community levels
2. To assess the district, health facility and community preparedness to provide RMNCAH and HIV services during the pandemic.
3. To obtain information on the implications of COVID-19 on the level of access and utilization of routine RMNCAH, HIV and other health services
4. To explore the effects of COVID-19 pandemic on mental health, intimate partner violence and gender roles
5. To assess the effects of COVID-19 on early child development, food security, feeding practices and nutrition among children under five years.
6. To generate recommendations for informing future national policy and public health response to health emergencies

 Uganda 2020-11-18 2023-11-18 Medical and Health Sciences Non-degree Award
Bonnie Fournier
ID: UNCST-2019-R000250
 Reducing HIV-related Stigma in School Children
REFNo: HS510ES

Specific research objectives:
● Objective 1: To assess the magnitude of change, among young people who receive the arts-based intervention, in measures of stigma (i.e., enacted, internal, anticipated, courtesy, and perceived), HIV knowledge and attitudes towards young people who are HIV+ and –affected;
● Objective 2: To assess the intervention effect on HIV testing behavior among HIV-negative sexually-active young people;
● Objective 3: To assess the intervention effect on linkage to care, initiation of Antiretroviral Therapy (ART), and adherence to ART among HIV+ young people;
● Objective 4: To evaluate how, and under what circumstances, the intervention had an effect.

 Canada 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Imelda Bates
ID:
Development of a complex quality improvement intervention for timely blood transfusions for the management of postpartum haemorrhage (PPH) in Uganda
REFNo: HS579ES

1. To map out active transfusing facilities and blood centres in two districts in Uganda and create a profile of baseline measures of quality of PPH management and blood transfusion services (e.g. availability of blood, safety of blood, timeliness of referrals of women with PPH, regular measurement of haemoglobin in PPH patients) for each district
2. To determine key barriers to the appropriate management of PPH, including blood transfusion
3. To gain stakeholder buy-in and contribution to a lead-on quality improvement intervention’s design from all levels, with a specific view to feasibility and sustainability
 UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Alison Elliott
ID: UNCST-2023-R006524
 “Establishing a Single-Sex Controlled Human Schistosoma mansoni Infection Model for Uganda: Safety and Dose Finding” (CHI-S-Ug1)
REFNo: HS697ES

Primary objective: To investigate (1) the safety and tolerability and (2) the infectivity of male Schistosoma mansoni (Sm) cercariae in healthy adult Ugandan volunteers with (a) minimal prior exposure to Sm, and (b) intense prior exposure to Sm.
Exploratory objectives: To investigate the kinetics of controlled infection with male Schistosoma mansoni cercariae in healthy adult Ugandan volunteers (a) with minimal prior exposure to Sm, and (b) with intense prior exposure to Sm. To investigate immunological, metabolic and microbiome changes after infection with Schistosoma mansoni male cercariae. To investigate volunteer and wider community understandings of CHI in the context of CHI-S.


UK 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Adegbola Tololupe Adesogan Carola
ID:
FEED THE FUTURE PESTE DES PETITS RUMINANTS VACCINE ASSOCIATE AWARD
REFNo: A77ES

In the course of the pilots, the project will conduct: • A rapid assessment of existing information and surveillance activities to identify the most relevant actions to reinforce surveillance and epidemiological assessments capacity and information. • At least one training workshop to enhance skills and establish epidemiological monitoring systems that meet both disease control and project applied research needs. • Targeted sero-sampling designed for the estimation of the basic reproductive number. • Participation in the investigation of outbreaks and facilitation of the collection of material for viral isolation and genomic analysis. • Mapping of virus flows and modeling of disease transmission as an approach to integrating data from diverse sources. • Areas targeted will be points of high virus circulation and will have substantial levels of PPR antibody; the project will measure the impact of vaccination on herd immunity and the frequency of disease events.
USA 2020-11-17 2023-11-17 Agricultural Sciences Non-degree Award
John  Ssempebwa
ID: UNCST-2020-R014966
 ASSESSMENT OF STATUS AND DEVELOPMENT OF FRAMEWORK AND GUIDELINES TO IMPROVE HEALTH AND SAFETY OF SWIMMING POOLS IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA
REFNo: HS730ES

Objectives
1. To determine the physio-chemical and microbiological quality of water in swimming pools.
2. To determine the knowledge, and practices of swimmers and operators regarding safety of
swimming pools.
3. To establish the hygienic and safety status at the swimming pools premises.
4. To establish a framework and guidelines to regulate operation of swimming pools in Uganda.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Jonathan Nsamba
ID: UNCST-2024-R003888
 Body composition and muscular health of children and adolescents diagnosed with type 1 diabetes mellitus in Uganda
REFNo: HS759ES

1. To determine the body composition of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
2. To determine the hand grip strength of children and adolescents diagnosed with T1DM as compared to their closely matched sex and age controls.
3. To examine the associations between dietary intake patterns, physical activity, nutrition status and body composition among children and adolescents diagnosed with T1DM
4. To understand the perceptions of newly diagnosed Type 1 Diabetes Mellitus children and adolescents about their disease status, barriers and facilitators to self-care.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
FADHIL GERIGA
ID: UNCST-2022-R011524
 Optimizing Nephroblastoma treatment outcomes in Uganda
REFNo: HS822ES

Primary Objectives:
o To determine the one-year survival of children with pathology confirmed nephroblastoma treated with multidisciplinary, stage-based care in Uganda.
o Assess the factors associated with morbidity and mortality among children with nephroblastoma.

Secondary Objectives:
o Characterize the frequency and spectrum of other malignancies that present similar to Nephroblastoma
o Characterize the social needs and health literacy of nephroblastoma patients and their caregivers at the UCI
o Assess quality measures of a multidisciplinary care, including:
- Treatment timing benchmarks following guidelines developed for UCI
- Adherence to treatment plan and elimination of loss to follow-up
o Assess social needs and provide a patient navigator for families of children with nephroblastoma and reduce the non-clinical barriers to care for children with nephroblastoma

Exploratory Objectives:
o To collect plasma for future studies evaluating circulating tumor DNA as a tool for diagnosis of pediatric kidney cancers and monitoring of patients with nephroblastoma.
o Collect stool specimens for future studies to define baseline factors in the stool microbiome that are associated with neutropenic fevers, sepsis and 12 months survival using combination of sequencing methods and stool ova and parasites evaluation.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 EXPLORING CHILDREN’S UNDERSTANDING OF COVID-19 AND ITS PREVENTIVE STRATEGIES IN UGANDA: A CROSS SECTIONAL STUDY AMONG CHILDREN AGED 10-13 YEARS IN HOIMA DISTRICT
REFNo: HS830ES

General objective

To explore children’s understanding of COVID-19 disease and related preventive measures, in order to generate information that will guide the development of evidence-based strategies for strengthening and improving children safety and wellbeing during and after the COVID-19 crisis.

Specific objectives

1.To establish the children’s knowledge of COVID-19 transmission and its preventative measures in Hoima Municipal Council

2.To describe how the COVID-19 preventative measures are understood and practiced by children aged 10 to 13 years in Hoima Municipal Council

3.To explore the enablers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

4.To explore the barriers for the recommended health measures for the prevention of COVID -19 among children aged 10 to 13 years in Hoima Municipal Council

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Formative Study to Understand Drivers and Barriers to Uptake of Permanent Methods of Family Planning Among Men and Women in Busoga Sub region
REFNo: HS862ES

The overall objective is to understand the factors that influence women, men and providers in Busoga region during the journey to access PMs to enable PSIU to design interventions.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
NAUME MUYANGA
ID:
UNDERSTANDING THE IMPACT OF GENDER BASED VIOLENCE ON HIV/AIDS PREVENTION AND TREATMENT HEALTH SEEKING BEHAVIORS AMONG TRANSWOMEN IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA.
REFNo: SS557ES

Broad objective:
To understand the impact of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Specific objectives:
1. To document the lived gender-based violence experiences among the transwomen in the greater Kampala metropolitan area, Uganda.
2. To explore the existing gender-based violence referral pathways used by the transwomen in the greater Kampala metropolitan area, Uganda.
3. To explore the impacts of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Uganda.
4. To identify priority issues for advocacy and programming in prevention and response to gender-based violence among the transwomen in the greater Kampala metropolitan area, Uganda.

 Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Susanna (Zanna) Clay
ID:
The origins of empathy- Investigating empathy development in the first two years of life
REFNo: SS596ES

Empathy – the sharing and understanding others’ emotions and thoughts – is an essential part of what it means to be human. While empathy underpins our most meaningful social interactions, we lack knowledge about its developmental and evolutionary origins. Thus far, research on empathy development remains limited, something which may have led to inaccurate conclusions that infants lack the capacity for empathy before their second year.. Although the view that infants lack empathy has recently been challenged, current research remains constrained by a lack of research attention as well as suitable methodologies to study early empathy. A key goal of this project is to address these limitations by conducting the first major study of empathy development across the first 2 years of life. By combining observations with novel experimental techniques our goal is study how the cognitive and affective components of empathy emerge.

Another objective is to investigate the impact that the social and cultural environment have on infant socio-emotional development. Research indicates that caregiving and the socio-cultural environment shape infant development, however, there is little research looking into how these factors shape empathy development. In addition, most developmental research so far has been conducted on infants from Western societies, also denoted as WEIRD (Western Educated Industrialised Rich Democratic) whilst ignoring cross-cultural variability. By focusing on a subset of Western societies, current developmental research is thus not representative of global diversity; ignoring insights from cross-cultural variation may lead to inaccurate interpretations.

In order to address this and understand how the socio-cultural environment shapes empathy development, it is essential to study how empathy develops in a more diverse cross-cultural sample. Through doing so, we can also address which aspects of empathy may be learned or socially-mediated, and which might reflect human universals. The current project aims to address this by studying the development of empathy and the influence of the socio-cultural environment. The capacity for empathy has far reaching consequences for how we function as a species and interact with others. A lack of capacity to care about others (empathy) can have many negative consequences for individuals and our societies, including reduced wellbeing, quality of social relationships, crime and mental health. Given the importance of empathy for our social and societal functioning, it is essential to know where empathy comes from and how it is shaped by social and cultural experiences.

This project represents a continuation and extension of the research activities of a current and approved research project, led by Professor Katie Slocombe, running on infant development in the Masindi district of Uganda. This project was approved by UNCST and UVRI (UVRI-045/2017). Our current project uses very similar methods and is planned to be conducted with the same local research assistants and communities who have participated in this research.

UK 2020-11-17 2023-11-17 Social Science and Humanities Degree Award
Kenneth Katumba Rogers
ID:
Developing a country-specific EQ-5D-5L value set and an inequality parameter for Uganda
REFNo: SS597ES

The primary objective of this study is to develop an EQ-5D value set for Uganda,

secondary objectives are:
● To explore the feasibility of a ‘lite’ valuation protocol in the LMIC setting
● To elicit a health inequality aversion parameter for Uganda
 Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
 Understanding Self Injection of DMPA-SC: Provider Research Uganda 2020
REFNo: HS938ES

The study is aimed at gaining a deep understanding of the consumer and health care provider journey is critically important to the introduction of family planning products into new districts. through answering the following questions:
1. What is the value proposition of self-inject for them?
2. What would increase their level of trust in women’s ability to successfully self-inject?
3. What would enable them to support consumers on the self-injection journey?
o What would be included in an optimal consumer initial training experience?
o What factors would support them to provide ongoing support for consumers who inject at home and experience side-effects?
o How could they better help consumers overcome barriers to access, including ensuring stock of DPMA-SC for client’s re-supply of product?
4. What factors would optimize provider training for self-injection?
o How could training be more convenient, effective, and of higher perceived value?
o What are the opportunities and barriers to using digital channels to learn and attend training on self-inject?
o What are the opportunities and barriers to using digital channels to train and support clients in using self-inject?

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
 Theoretical analysis of the pediatric discharge process in Uganda: A process evaluation
REFNo: HS929ES

The primary objective of this study is to build a theoretical model of the current pediatric discharge pathway from the time of admission until post-discharge follow-up.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
 Co-infection of SARS-CoV-2 with M. tuberculosis & other respiratory pathogens (SARS-CoV-2-
REFNo: HS940ES

(1) Estimate the prevalence of coinfection of SARS-CoV-2 with other respiratory pathogens, (2) Investigate the impact of coinfections on molecular testing for COVID-19 infection and, (3) Apply metagenomics whole genome sequencing for unbiased detection of respiratory pathogens directly in respiratory samples
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
 Rapid Assessment of COVID-19 Impact on Family Planning Access and Use
REFNo: HS952ES

1. Document the proportion of Viamo 3-2-1 users who have their demand for family planning satisfied by modern methods during the pandemic and the recovery process;
2. Measure the proportion of current modern contraceptive users who have obtained their preferred contraceptive method among women who initiated or resupplied their method during the pandemic and the recovery process;
3. Describe barriers in accessing family planning services to ensure voluntary method use and choice during the pandemic and the recovery process.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 International Registry of Healthcare Workers Exposed to COVID-19 Patients (UNITY Global) at Selected Health facilities in Uganda
REFNo: HS964ES

Primary Objective
To assess the association of potential prophylactic treatments with reduced risk of COVID-19 (or SARS-CoV-2 infection) in HCWs caring for COVID-19 patients at selected health facilities in Uganda.

Secondary objectives
i) To characterize the type of potential prophylactic treatments, by dose and duration, overall, and by region and or selected health facilities (sites) in Uganda.
ii) To explore the key factors (for example, use of PPE, HCW and healthcare facility characteristics, underlying co-morbidities, household history and COVID-19 exposure) modifying the risk of COVID-19 among HCWs at selected health facilities (sites) in Uganda.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
 Antibacterial activity of Rosmarinus officinalis L. and Curcuma longa against bacteria from clinical specimens in Uganda- A therapeutic option for multidrug resistant bacteria (ARC study)
REFNo: NS141ES

Main objective
To determine the activities of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts against bacteria isolated from clinical specimens at the Makerere University Microbiology Clinical Laboratory (MUCML) from January 2018 to December 2019

Specific objectives
1. To develop the chemical composition of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts
2. To determine the Minimum Inhibitory Concentration of plant extracts from Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) against bacteria isolated from clinical specimens
3. To determine the synergistic effects of combination of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) and antibiotics against bacteria isolated from clinical specimens in the MUCML
Uganda 2020-11-17 2023-11-17 Natural Sciences Non-degree Award
Wenceslaus Sseguya
ID: UNCST-2019-R000877
 The Effect COVID-19 Pandemic on the Management and Control of Diabetes in Patients Receiving Support from a Life for a Child-Supported Diabetes Program in Kasese District, Western Uganda
REFNo: HS987ES

• To describe problems and challenges experienced by patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To explore personal experiences of health workers and primary caregivers regarding diabetes management and control of patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To document mechanisms used to solve problems and overcome challenges encountered by patients with insulin-requiring diabetes, caregivers and health workers during the COVID-19 pandemic.
• To describe the perceived support needs for patients with insulin-requiring diabetes during the COVID-19 pandemic period and post the COVID-19 period.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Interventions for Improved Post-partum ART Continuation and HIV Testing of Male Partners of Women in PMTCT B+ in Uganda
REFNo: HS991ES

Aim 1: To evaluate whether the proportion of male partners of pregnant HIV-positive women who test for HIV, is improved after distribution of a letter of invitation to a wellness visit (dual syphilis and HIV rapid test, blood pressure, visual acuity screening and COVID-19 screening) to their female partners compared to the standard of care (standard of care invitation letter from the clinic).

Aim 2: To evaluate whether POC viral load testing with same day ART adherence support improves viral suppression among pregnant and post-partum women living with HIV compared to standard of care lab-based HIV VL testing.

Aim 3: To assess the proportion of HIV-negative male partners who initiate PrEP and HIV positive men who initiate ART among male partners who test for HIV through a wellness visit or standard of care letter from the clinic.

Aim 4: To evaluate acceptability and preferences for HIV testing and other health services among pregnant women and male partners using mixed methods.
 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Namulema Edith
ID:
EARLY RESUMPTION OF SEXUAL INTERCOURSE IN THE PUERPERIUM AMONG MOTHERS IN UGANDA: BURDEN AND THE EFFECT OF HEALTH EDUCATION ON PUERPERAL ABSTINENCE
REFNo: HS1050ES

1)To establish the burden and factors associated with of early resumption of sexual intercourse within the puerperium (ERSP) among new mothers in Kawempe National Referral Hospital (Kawempe NRH) and Mengo Hospital.
2)To explore the perceptions, attitudes, experiences and actions towards the ERSP among new mothers and their partners in Kawempe NRH and Mengo Hospital.
3)To explore how health care workers in Kawempe NRH and Mengo Hospital perceive the level of puerperal sexual health care services provided to couples with new babies.
4)To identify strategies that may delay the early resumption of sexual intercourse among new mothers at Kawempe NRH and Mengo Hospital and design an appropriate psycho-sexual educational intervention to reduce ERSP.
5)To evaluate the effect of psycho-sexual health educational intervention on reducing ERSP among couples with new babies at Kawempe NRH and Mengo Hospital.

 Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Degree Award
Joseph Musaazi
ID:
USING ROUTINELY COLLECTED SECONDARY DATA TO ESTIMATE UPTAKE AND EFFECT OF ISONIAZID PREVENTIVE THERAPY ON TUBERCULOSIS INCIDENCE AND PREGNANCY OUTCOMES AMONG PEOPLE LIVING WITH HIV RECEIVING CARE IN PUBLIC HEALTH FACILITIES IN UGANDA.
REFNo: HS729ES

1) To determine trends of IPT uptake and completion rates among PLHIV receiving HIV care at public health facilities in Uganda.
2) To determine the effect of IPT on TB incidence among PLHIV receiving care at public health facilities in Uganda.
3) To estimate the effect of IPT on pregnancy outcomes among women living with HIV (WLHIV) receiving care at public health facilities in Uganda.

 Uganda 2020-11-16 2023-11-16 Medical and Health Sciences Non-degree Award
Jamila Nansimbe
ID:
UNDERSTANDING THE MEDICAL SUPPLY CHAIN BOTTLENECKS IN THE PUBLIC HEALTH SECTOR IN UGANDA (CASE OF KAMPALA CAPITAL CITY AUTHORITY HEALTH CENTERS)
REFNo: HS939ES

1. To examine the main causes of stock-outs of medicine and health supplies.

2. To examine the main causes of expiry of medicines and health supplies.

3. To recommend supply chain interventions to improve availability of medicines and health supplies.

 Uganda 2020-11-13 2023-11-13 Medical and Health Sciences Non-degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 A5372: Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals
REFNo: HS624ES

Primary Objectives;

-To determine the dosing for DTG that, when given together with 1HP, achieves target exposures (Ctrough) of standard-dose DTG when it is given without RPT.
-To estimate the steady state plasma pharmacokinetics (PK) of DTG when DTG 50 mg is dosed twice daily (BID) with 1HP.
-If Arm 2 opens, to estimate the steady state plasma PK of DTG when DTG 50 mg is dosed once daily (QD) with 1HP.

Secondary Objectives;

-To evaluate the safety of coadministration of DTG based ART with 1HP.
-To evaluate the tolerability of coadministaration of DTG based ART with 1HP
-To estimate the proportion of participants who maintain virologic suppression when DTG based ART is coadministered with 1HP

 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Pauline Amuge Mary
ID:
Community-based initiation and delivery of isoniazid preventive therapy (IPT) among household TB contacts in Uganda: A pilot project in Southwestern Uganda. Short Title: Community-Based TB prevention (Acronym: COMBAT TB).
REFNo: HS768ES

Primary Objective:
To assess the uptake of IPT among household TB contacts <5 years of age receiving IPT in the community delivery approach.

Specific Objectives:
1. To determine IPT completion rates among household TB contacts <5years of age enrolled in community-based delivery approach compared to those in the health facility-based IPT delivery approach.
2. To identify the factors that facilitate or hinder IPT uptake in the community-based delivery for household TB contacts <5years of age.

3. To determine the feasibility of community-based IPT delivery for household TB contacts <5years of age.
4. To determine the factors that facilitate or hinder IPT completion among household TB contacts <5years of age who initiate IPT.


 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Denis Kyabaggu Senkandwa
ID: UNCST-2023-R005881
 INFLUENCE OF SP110 POLYMORPHISMS IN HUMAN MACROPHAGES ON PULMONARY TUBERCULOSIS DISEASE AMONG UGANDANS
REFNo: HS870ES

-To identify, using Next Generation DNA Sequencing (NGS) technology, the SP110 gene polymorphisms among adult Ugandan pulmonary tuberculosis (PTB) disease patients reporting to Mulago National Referral hospital TB clinic.
-To determine the effect of the commonest SP110 SNPs identified in Ugandans on in vitro infection kinetics of MTB as measured by confocal microscopy techniques, in human monocytic leukemia THP-1 macrophage tissue cultures.
-To determine the in vitro effect of the top 3 SP110 SNPs among Ugandans on infection kinetics of MTB lineages 2, 3, 4 and H37Rv isolates in human monocytic leukemia THP-1 macrophage tissue cultures using confocal microscopy.
-To determine the SP110 SNPs present among TB patients co-infected with HIV at Mulago National Referral Hospital TB clinic.
 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 PILOT OF A NETWORK-DRIVEN, ADVOCACY INTERVENTION TO PROMOTE CERVICAL CANCER SCREENING IN UGANDA
REFNo: HS943ES

The proposed intervention development study seeks to improve cervical cancer screening in Uganda by engaging and training local public health researchers and program implementers, and empowering women living with cervical cancer risk (WLCCR), defined as women who have ever received treatment for pre-cancerous or cancerous lesions, to advocate for CC screening and early treatment among women in their social networks. Specifically, the study will aim to: 1. Assess the feasibility and acceptability of implementing a cervical cancer screening advocacy intervention with WLCCR, who will be trained to be advocates for CC screening and treatment behaviors in their social networks. 2. Assess preliminary intervention effects on the CC screening (primary outcome) and treatment behaviors of women in contact with the WLCCR advocates and diffusion of anti-stigma messages across social networks. 3. Explore characteristics of women who more effectively engage in screening advocacy (in terms of socio-demographics, network characteristics, and type of social network members receiving advocacy). 4. Increase capacity among local researchers and program implementers to conduct public health research on cervical cancer control and use social network-based intervention and measurement methods. The intervention will be implemented in three phases, and for each phase, we will seek ethical clearance and approval prior to data collection. At the moment, we are seeking ethical clearance for the first phase where we intend to conduct focus group discussions to obtain women's perceptions and suggestions about the intervention to inform the development of the intervention.
 Uganda 2020-11-12 2023-11-12 Medical and Health Sciences Non-degree Award
Amon Agaba
ID:
The quality and safety standards of herbal medicine production and vending in greater Mbarara District
REFNo: HS720ES

General Objective:
To document the adherence and practice required to maintain the quality and safety of herbal medicine production and vending in Mbarara District.

Specific Objectives:
I.To document the adherence to standard herbal medicine production guidelines by herbal medicine producers and vendors in Mbarara District
II.To explore the enablers and barriers to adherence to the recommended guidelines that govern the production and vending of herbal medicine in Mbarara District.

 Uganda 2020-11-11 2023-11-11 Medical and Health Sciences Non-degree Award
Josephine Nabukenya Kwagala
ID:
ASSESSING THE POTENTIAL FOR TRANSFORMING HEALTH IN UGANDA THROUGH AN ELECTRONIC HEALTH DATA SHARING PLATFORM AND DATA SCIENCE
REFNo: HS1005ES

General Objective:
To explore the readiness malaria and HIV as potential demonstrator conditions for an EHR data capturing and processing system infrastructure and analytical methods that could support Uganda’s Ministry of Health and related health institutions to provide responsive care and interventions based on real-time surveillance.

Specific Objectives:
Objective 1: To (a) develop a complete understanding of the routine care data currently captured and all surrounding dynamics including timing of capture by whom and how and what the current state of onward use is and (b) determine how these will influence data capture with electronic point of care capture systems.

Objective 2: To determine what technical, ethical/governance and workforce infrastructure are required for a timely model data capture system that addresses medical, public health and research needs of stakeholders.

Objective 3: In order to determine readiness, we will (a) model the cost of each proposal/ model system and determine on-going cost and potential cost recovery, including the cost of all other components (i.e., Buy-in, Timeliness, Capability) and determine what would be required to eliminate key barriers; and (b) map our data to EHR data capture and processing readiness frameworks.


Objective 4: To provide examples of cost effectiveness by determining how much additional malaria and/or HIV control would be required to offset the cost of the system over various time periods.

Uganda 2020-11-11 2023-11-11 Medical and Health Sciences Non-degree Award
Moses  Mulumba
ID: UNCST-2021-R013832
 National Study on the impact of contentious issues and masculinities on the realization of Sexual and Reproductive Health and Rights in Uganda
REFNo: SS537ES

General Objective: To generate evidence for SRHR advocacy and programming in Uganda
Specific objectives are;
1. To document the journey of the Sexual and Reproductive Health and Rights movements in Uganda
2. To explore the relationship between masculinities and sexual reproductive health and rights
3. To examine the influence of contentious issues like abortion, and LGBTQI on the realization of SRHR

 Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
Robert Downing George
ID: UNCST-2020-R014615
 Evaluation of the Clinical Performance of a Plastic Capillary Tube with the Determine HIV-1/2, Determine HIV Early Detect and Determine HBsAg 2 Rapid Tests
REFNo: HS895ES

The primary objective of this study is to evaluate the performance of a new plastic capillary tube for the transfer of a capillary finger-stick blood sample to 3 rapid test platforms; the Determine HIV-1/2 test platform, the Determine HIV Early Detect test platform and the Determine HBsAg 2 platform. The HIV and HBsAg results obtained using the new plastic capillary tubes to transfer capillary whole blood to the test devices will be evaluated against the HIV and HBsAg results obtained using a micropipette to transfer a whole blood venous sample from the EDTA Vacutainer tube to the same testing platforms, with discrepant result resolution where required. The new plastic capillary tubes have been verified in an internal performance study at the Abbott laboratories.
 UK 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Edward  Bitarakwate
ID:
Evaluation of Patient and Program Outcomes Achieved through EGPAF-supported Integrated HIV and TB Prevention, Care, and Treatment Programs in Uganda
REFNo: HS930ES

Primary Objectives:
1.To determine patient and program outcomes for children, adolescents and adults receiving HIV and TB services in EGPAF supported facilities and through EGPAF supported programs.

Secondary Objectives:
1. To determine outcomes of HIV testing strategies targeted at identifying HIV positive children, adolescents, and adults in facilities and the community including the number and proportion identified as HIV-positive, linked to HIV services, and initiated on ART in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome along the testing to treatment cascade.

2. To determine clinical and laboratory outcomes among HIV-positive children, adolescents and adults enrolled in HIV services such as morbidity (including coinfections), mortality, ART regimen, ART adherence, retention in care, viral suppression, and disease progression in EGPAF supported facilities and through EGPAF supported programs.
a. To determine individual, population, and program characteristics/factors associated with each outcome, including baseline clinical characteristics before initiating ART.

3. To determine the outcomes of HIV prevention activities (including PMTCT) among pregnant women, discordant couples, adolescents and other key and priority populations in facilities and the community including the number accessing prevention services by risk category, retention in services, and seroconversion rates.
a. To determine individual, population, and program characteristics/factors associated with the HIV prevention outcomes.

4. To determine clinical and laboratory outcomes among children, adolescents and adults accessing TB screening/diagnosis, prevention, and treatment services such as HIV/TB coinfection rates, initiation and adherence to IPT, initiation and adherence to TB treatment, retention in care, treatment outcomes for drug resistant TB, mortality.
a. To determine individual, population, and program characteristics/factors associated with each outcome.

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Harriet Mayanja-Kizza
ID: UNCST-2021-R013074
 “Assessment of circulating proteins in Ugandan tuberculosis household contacts for latent TB infection biomarker development: Version 1.0 dated 14 Sept 2020”
REFNo: HS958ES

Refine our protein signature to function in HIV-positive persons, incorporating cytokine and chemokine markers as needed.
2. Refine our protein signature to identify Mtb infection that has developed within a 6-month timeframe.

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Esther Nanfuka Kalule
ID:
Livelihood Resilience During the COVID-19 Lockdown: Practices of Informal Sector Populations in the Urban and Peri-urban Settings of Kampala and Wakiso Districts
REFNo: SS619ES

The study will specifically:
• Examine the current livelihood practices and resources among urban informal sector workers in the context of restricted mobility and social distancing
• Examine the opportunities and challenges for vulnerable urban informal sector workers to negotiate and reconfigure livelihood sources including social networks and social capital for support in a lockdown situation
• Assess the most valued livelihood sources (assets, capabilities, activities) under the lockdown and preferred areas of allocating available resources among different categories of the informal urban population
• Examine the potential and perceived risks (including public health) of the livelihood activities undertaken during the COVID-19 lockdown

 Uganda 2020-11-10 2023-11-10 Social Science and Humanities Non-degree Award
ARTHUR  SEKIZIYIVU BRIAN
ID:
END-LINE EVALUATION OF AN HIV PREVENTION PROJECT IMPLEMENTED BY UGANDA PEOPLE’S DEFENSE FORCES AND PACE
REFNo: HS989ES

I. Measure changes in the knowledge, attitudes and practices among the military and AGYW to adopt and sustain positive behavior change.
II. Identify challenges, innovations, lessons, and success stories across the interventions
III. Identify the opportunities to integrate prevention interventions within (into) an HIV care program

 Uganda 2020-11-10 2023-11-10 Medical and Health Sciences Non-degree Award
Hannington Odongo Jawoko
ID: UNCST-2024-R002457
 The Relationship between Social Governance and Smallholder Farmer Socio-Economic Resilience: Moderating Effects of Pluralistic Agriculture Extension Service Provision in Northern Uganda
REFNo: A78ES

To investigate the moderating effects of perceptions of the quality of pluralistic agricultural extension services provision on social governance exhibited in participatory local government planning and budgeting process.

To examine the influence of social governance exhibited in participatory local government planning and budgeting process on the values and needs of smallholder farmers in northern Uganda.

To assess the impacts of perceptions of the quality of pluralistic agricultural extension services provision on socio-economic resilience of smallholder farmers in northern Uganda.

To examine the impacts of social governance exhibited in participatory local government planning and budgeting process on smallholder farmer’s socio-economic resilience in northern Uganda.

 Uganda 2020-11-09 2023-11-09 Agricultural Sciences Degree Award
Anthony Mugeere Buyinza
ID:
THE IMPRINT OF EDUCATION: A LONGITUDINAL COHORT STUDY OF AFRICAN ALUMNI OF THE MASTERCARD FOUNDATION SCHOLARS PROGRAM
REFNo: SS543ES

(i) To provide evidence at multiple levels on the individual, structural, contextual and programmatic factors that mediate Scholars’ outcomes especially with regards to “return”, “giving back”, “transformative and ethical leadership”

(ii) To assess the imprint of education on the lives of individuals, communities and societies in contexts such as those on the African continent in which Mastercard Foundation (MF) provides scholarships.

(iii) To examine the links between socio-economic inclusion, education and development.

(iv) To understand what works and why, as well as what might be done to improve the MSP and maximise the impact of Scholars as agents in the social and economic transformation of the African continent (by considering their social networks, support and training received, the way in which institutions contributed to their success, and their employment and employment creation trajectories).
 Uganda 2020-11-09 2023-11-09 Social Science and Humanities Non-degree Award
Augustine Ssevviri Kaddu Musisi
ID:
Using the Health Belief model to increase the level of knowledge, attitudes and practices of COVID-19 prevention measures in Wakiso district, Uganda
REFNo: HS883ES

1.0 Main Objective
To understand the level of adherence towards the COVID-19 guidelines and assess the knowledge and attitudes regarding COVID 19 in order design a behavioral change intervention that enhances knowledge and promotes compliance to the prescribed COVID-19 practices at the grassroots level in Wakiso district, Uganda
1.1 Specific Objectives
• To determine the level of knowledge about the prevention of COVID-19 among the people in Wakiso district
• To understand community attitudes towards the prevention of COVID-19 in Wakiso district
• To determine the level of adherence to COVID-19 prevention guidelines among community members in Wakiso District
• To design a behavioral change communication intervention for improving people’s knowledge, attitudes and level of adherence towards COVID-19 guidelines

Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
willy waninga
ID:
The use of ICT in the teaching of integrated science in Primary Teachers' Colleges in Uganda: A case of Four Primary Teachers' Colleges
REFNo: SS594ES

1. To find out ICT tools used by science tutors in teaching integrated science education
2. To find out how science tutors use technological content knowledge in planing integrated science education lessons.
3. To find out how integrated science education tutors integrate technological content knowledge in the pedagogy of science education.
 Uganda 2020-11-09 2023-11-09 Social Science and Humanities Degree Award
Herbert Kayiga Kayiga
ID:
IMPACT OF COVID-19 PANDEMIC ON MATERNAL AND NEWBORN HEALTHCARE SERVICE DELIVERY IN PRIVATE AND PUBLIC FACILITIES IN UGANDA
REFNo: HS924ES

STUDY OBJECTIVE:
To determine the impact of COVID-9 pandemic on the provision of maternal and newborn services in Kampala, Uganda

SPECIFIC OBJECTIVES:
1. To determine the quality of maternal and newborn service provision in Kampala, Uganda before the COVID-19 pandemic.
2. To determine the quality of maternal and newborn service provision in Kampala, Uganda during the COVID-19 pandemic.
3. To seek understanding of the experiences of the health workers as they provide maternal and newborn services in Kampala, Uganda.
4. To seek understanding of the pregnant and breastfeeding mothers’ experience as they seek maternal and newborn services in Kampala, Uganda.

 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Matthew  Cotten Louis
ID:
Local sequencing of SARS-CoV-2 from Uganda COVID-19 cases
REFNo: HS936ES

To document the transmission dynamics of COVID-19 in Uganda using full viral genome sequencing
 USA 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
 Title: Analysis of A Tool To Assess Psycho Social Spiritual Healing: Cognitive Interviewing
REFNo: HS957ES

1. To determine the face and content validity of the NIH-HEALS

2. To determine the comprehensiveness, comprehensibility and acceptability of the NIH HEALS in Uganda
 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
 Leveraging the HIV platform for hypertension control in Uganda (INTEGRATED HIV/HTN)
REFNo: HS979ES

1 To determine the effectiveness of an integrated HIV/HTN care model on HTN and dual
HIV/HTN control among adult patients in HIV clinics.
2 To assess the barriers and facilitators of the integrated HIV/HTN care model for HIV
patients at different levels.
3 To determine the cost, cost-effectiveness and incremental gain costs of the integrated
HIV/Hypertension care model approach
 Uganda 2020-11-09 2023-11-09 Medical and Health Sciences Non-degree Award
Grace Edwards
ID:
An exploration of the need for Nursing and Midwifery Leadership Capacity Building in Uganda
REFNo: HS562ES

The study is aimed at exploring the leadership training needs for nurses and midwives in Uganda, in order to develop recommendations for developing nursing and midwifery leaders in Uganda and draft a leadership training programme.
 UK 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Moses Adroma
ID: UNCST-2019-R000360
 INCIDENCE & PREDICTORS OF ABNORMAL RENAL FUNCTION THREE MONTHS AFTER DELIVERY AMONG PREECLAMPSIA SURVIVORS AT MULAGO HOSPITAL
REFNo: HS341ES

To determine the incidence and predictors of abnormal renal function three months after delivery among preeclampsia survivors at Mulago Hospital.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Kintu  Mugagga
ID:
Comparative Assessment of Anatomical and Neuro-Cognitive Characteristics Between Vaginally And Caesarean Section Delivered Children of 1-2 years Age At Mbarara Regional Referral Hospital, South-Western Uganda
REFNo: HS397ES

i) To describe the differences in the head-size and body height between VD and CSD children at 1-2 years of age born at Mbarara Regional Referral Hospital.


ii)To describe the differences in neurocognitive characteristics between VD and CSD children at 1-2 years of age born atMbarara Regional Referral Hospital.


iii)To describe the perinatal and socio-demographic characteristics of the mothers to the VD and CSD childrenof 1-2 years of age delivered at Mbarara Regional Referral Hospital.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
 Owning our future through community engagement: enhancing uptake of COVID-19 prevention and mitigation measures”
REFNo: HS858ES

Specific Objectives
1. Ascertain the:
a) Prevailing attitudes and perceptions towards COVID-19 mitigation measures and community response and adaptation (behaviours, practices) to the “new social norms” imposed by the emergency response;
b) Short-term socioeconomic impact and community coping mechanisms
2. Develop and implement a community engagement intervention for enhancing uptake of the recommended COVID-19 public health and social mitigation measures.
3. Evaluate the effects of the intervention developed in 2 above on acceptance and uptake of the COVID-19 prevention and mitigation measures.

Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Martha Nabadda
ID:
A qualitative case study exploring health workers’ perspectives on facilitators and barriers to comprehensive management of sickle cell disease in young adults aged 18 – 25 years accessing primary care in Uganda.
REFNo: HS616ES

i. To investigate the facilitators and barriers to comprehensive management of sickle cell disease, using a focused group discussion and ten semi-structured, in-depth interviews with healthcare workers at three sickle cell clinics in Uganda.

ii. To explore the care and support needs specific to young adults with sickle cell disease accessing the health system at the point of primary care.

iii. To make care and policy recommendations for the Ministry of Health to improve guidelines for the provision of sickle cell disease care in public health facilities in Uganda.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Degree Award
Abner Tagoola
ID: UNCST-2021-R013446
 Enhancing maternal participation in neonatal hospital care using an adapted Family Integrated Care (FICare) program
REFNo: HS632ES

The purpose of this study is to adapt and test a model of enhanced maternal participation (FICare) in a neonatal hospital unit in Uganda. This is with the goal of increasing the level of patient monitoring and ultimately improving the quality of care that sick and small newborns receive in the hospital. Specifically, the study is
1. To determine the acceptability of implementing an adapted FICare model, specifically maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase I)
2. To test the feasibility of implementing maternal assessment of newborn danger signs, weight and feeding, in a neonatal hospital unit in Uganda (Phase II)

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Gorrette Nalwadda Kayondo
ID:
Analysis of Reproductive Maternal Newborn Child Adolescent Health Referral Pathways in Rural and Urban Health Care Settings in Uganda
REFNo: HS646ES

1. Examine the referral pathways relevant to RMNCAH from community level to the various health system levels that is HC II – IV, district and regional referral hospitals.
2. Explore the key challenges, lessons learnt and opportunities that enable or hinder RMNCAH referrals
3. Propose practical ways of improving the referral pathways for better RMNCAH service delivery outcomes in Uganda.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
David Ayebare Santson
ID:
Factors Influencing Cervical Cancer Screening In Sheema District
REFNo: HS661ES

To identify the socio-demographic, cultural, and economic factors influencing low uptake of Cervical Cancer Screening services among women aged 25-49 years in Sheema district.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Lydia Nakiyingi
ID:
Effect of the COVID-19 situation on vulnerable HIV-infected and -affected adolescent girls and young women: A case of Kampala district
REFNo: HS746ES


General objective
• To determine the effect of the Uganda COVID-19 response on underprivileged HIV-infected and affected adolescent girls and young women with the aim is to develop relevant interventions, informed by their experiences, to address their actual needs.
Specific objectives:
• Document experiences of underprivileged HIV-infected and -affected adolescent girls and young women in Kampala during the COVID-19 period.
• Determine unmet needs of underprivileged HIV-infected and -affected adolescent girls and young women during the COVID-19 period.
• Assess perceptions of HIV-infected and affected adolescents towards the COVID-19 prevention interventions.
• Determine effects of the COVID-19 situation on physical, mental and psychosocial wellbeing of underprivileged HIV-infected and -affected adolescent girls and young women.
• Develop COVID-19 context-specific implementable recommendations (guided by the study’s findings) to inform interventions for underprivileged HIV-infected and -affected adolescent girls and young women.

 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Timothy  Muwonge Ronald
ID: UNCST-2020-R014680
 DIAL-COVID: Remote mitigation through telephone symptom surveillance in refugee settlements in Uganda
REFNo: HS901ES

The primary objective is to assess uptake and validate a mobile telephone surveillance and mitigation tool (“Dial-COVID”) in refugee settlements in Uganda.
The secondary objectives are:
1. To implement a mobile telephone interactive voice response (IVR) symptom tracker and information dissemination tool (“Dial-COVID”) and assess its uptake in the refugee population.
2. To iteratively test and validate a screening algorithm for COVID-19 using symptoms and risk factors reported by Dial-COVID users to predict infection determined by positive COVID-19 tests.
3. To assess COVID-19 risk perceptions and knowledge among refugees.
4. To understand barriers and facilitators to adoption of COVID-19 prevention and control measures in refugee settlements.
 Uganda 2020-11-04 2023-11-04 Medical and Health Sciences Non-degree Award
Sarah  Skeen
ID:
The Sharing Stories Project: Promoting playful parenting through sharing digital books in the COVID-19 era
REFNo: SS517ES

Relying on in-person book-sharing models, we will adapt this project to be deliverable over WhatsApp, and engage parents through sending digital books, holding weekly webinars, and sending individualized messages to support parents’ mental health and wellbeing. We will partner with the Regional Psychosocial Support Initiative (REPSSI) and the Africa Early Childhood Network (AfECN) to deliver this digital intervention to parents with young children with the aim to promote parenting through play, parental sensitivity, responsiveness and mental health, and child social, emotional and cognitive development.

South Africa 2020-11-04 2023-11-04 Social Science and Humanities Non-degree Award
SHEBA  NAKACUBO GITTA
ID:
How can UK Health Worker Volunteers Effectively and Sustainably Support the Development of Ugandan Health Workforce?
REFNo: HS837ES

1. To provide an overview of current approaches and priorities to health worker volunteer placements in Uganda;
2. To identify the priority needs for health worker volunteer placements in partnership with the Ministry of Health;
3. To give insight into the volume of health worker placements available and make recommendations on how such schemes can be designed to achieve mutual benefit for the UK, Uganda and other host countries.

 Uganda 2020-11-02 2023-11-02 Medical and Health Sciences Non-degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Development of a community-led intervention to prevent and control unintended immediate socio-economic and health consequences of COVID-19 among slum dwellers in Kampala, Uganda 2020
REFNo: SS638ES

1. To assess the immediate socio-economic and health vulnerabilities due to COVID-19 among slum dwellers of Bwaise I and Bwaise III, in Kampala Uganda.
2. To explore predisposing factors to the vulnerabilities.
3. To determine the level of adherence and barriers to compliance with COVID-19 prevention measures.
4. Use the Human centred design (HCD) to explore and design potential interventions to reduce vulnerabilities and determine their feasibility.
5. To explore lessons for future policy and designing inclusive outbreak interventions for slum dwellers.

 Uganda 2020-10-29 2023-10-29 Social Science and Humanities Non-degree Award
Namuguzi Namuguzi Mary
ID:
Exploring Individual Health-Promoting Lifestyle Behaviours for Prevention of Hypertension in Rural Communities of Uganda
REFNo: HS617ES

1. What knowledge do individuals have about prevention of hypertension in rural communities of Uganda?
2. What individual health lifestyle behaviours influence the prevalence of hypertension in rural communities of Uganda?
3. What is the prevalence of hypertension in two rural communities (Mende and Kasengejje) of Uganda?
4. How do individuals in rural communities of Uganda prevent hypertension?
5. What interventions are effective for the prevention of hypertension in Low and Middle-income countries?

 Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Degree Award
Viola  Nyakato Nilah
ID: UNCST-2021-R013698
 Understanding the Marginalized Indigenous Batwa People of South-Western Uganda
REFNo: SS452ES

The general objective of the study is to generate data on the livelihood of Batwa indigenous community living in the districts of Kabale, Kisoro, Rubanda and Kanungu in Southwestern Uganda, in order to build evidence around the factors that compromise their livelihoods across policy, access to services and resources, culture and their history/heritage.

The specific objectives of the study will be:
1.To assess and understand the vulnerable issues and factors of marginalization of the Batwa from the districts of Kabale, Kisoro, Rubanda and Kanungu
2.To generate evidence on the social, structural and other barriers the Batwa Community face for their livelihood improvement interventions
3.To undertake participatory approaches to develop and evaluate development interventions improvement for the Batwa livelihoods
4.To propose recommendations on how to develop appropriate livelihood improvement programmes and policies for Batwa indigenous people communities living South Western Uganda.

 Uganda 2020-10-27 2023-10-27 Social Science and Humanities Non-degree Award
LYNDA NAKALAWA ESTHER
ID:
The dilemma of youth empowerment in Uganda:interrogating the mindset question
REFNo: SS454ES

Research Questions
Overall Research Question: How have the mindsets of youth from selected youth empowerment programs in Uganda been shaped by the social, cultural and historical processes at play in the society within which these programs operate.
Specific research questions
1. How are youth positioned in the social, cultural and historical discourse around youth empowerment in Uganda?
2. What is the impact of this discourse on the mentalities, including attitudes, unconscious biases or ingrained beliefs of youth in selected youth empowerment programs in Uganda?
3. How are the youth’s mindsets expressed in their behavior or actions?
 Uganda 2020-10-27 2023-10-27 Social Science and Humanities Degree Award
Rodgers Tugume
ID:
prevalence and factors associated with pelvic organ prolapse among women attending gynaecological outpatient clinic of Mbarara Regional Referral Hospital
REFNo: HS706ES

1.To determine the prevalence of pelvic organ prolapse among women attending gynaecological outpatient clinic at Mbarara regional referral hospital.
2.To determine the commonest stage of pelvic organ prolapse at presentation of women attending gynecological outpatient clinic at MRRH.
3.To identify the socio-demographic, obstetric, gynaecological, and medical factors associated with pelvic organ prolapse among women attending gynecological clinic at Mbarara Regional Referral Hospital.

 Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Degree Award
George  Semivule William
ID:
MANAGEMENT PRACTICES AND IMPLEMENTATION OF STRATEGIC PLANS, IN NDEJJE UNIVERSITY UGANDA
REFNo: SS480ES

1. To determine the effect of planning implementation of of strategic plans on Ndejje University.

2. To assess the effects of organizing on implementation of the strategic plans of Ndejje University.

3. To establish how leading affects the implementation of strategic plans of Ndejje University.

4. To determine the effect of controlling on implementation of the strategic plans of Ndejje University.
Uganda 2020-10-27 2023-10-27 Social Science and Humanities Degree Award
Felix Twinomucunguzi Rutaro Baineki
ID:
A Socio-Technical Decision Support Framework for Reducing Groundwater Contamination Risk in Peri-Urban Areas, Kampala
REFNo: SS482ES

Determine the recent extent of groundwater contamination in low income peri-urban areas, with focus on emerging organic contaminants.

Investigate the specific vulnerability to emerging groundwater contamination in low income peri-urban areas.

Assess the key socio-institutional factors influencing increased risk of groundwater contamination in low income peri-urban areas.

Develop qualitative decision support framework for reducing risk of groundwater contamination in low income peri-urban areas.

 Uganda 2020-10-27 2023-10-27 Social Science and Humanities Degree Award
Hakim Sendagire
ID:
Evaluation of the World Health Organization criteria and the Uganda National Policy; antiretroviral treatment regimen switch, from first line to second line HIV drug combinations, following ‘virological failure but without drug resistance testing’.
REFNo: HS743ES

1. To determine the prevalence of virologic failure among patients receiving first line failure in Uganda.
2. Establish the resistance patterns at the time of switching therapy.
3. Validate the correctness of the decision to switch therapy, thereby evaluate the WHO public health approach in management of ART.

Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Non-degree Award
Jackson Orem
ID: UNCST-2021-R012016
 Effect of Patient Navigation Services on Patients’ Experience of Cancer Care and Adherence to Treatment at Uganda Cancer Institute 2020-2023
REFNo: HS950ES

Overall research Objective
To assess the effect of patient navigation program on patients’ experience of cancer care and adherence to treatment at Uganda Cancer Institute
Specific research Objectives
1.To assess changes in patient barriers to accessing care and adhering to treatment as a result of the implementation of patient navigation services at UCI
2.To assess the changes in patients’ experience of cancer care as a result of the implementation of patient navigation services at UCI
3.To assess the changes in adherence to treatment as a result of the implementation of patient navigation services at UCI.

 Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Non-degree Award
Patrick  Ogwok
ID:
Effectiveness of a combined food literacy and physical activity intervention to optimize metabolic health among women of reproductive age in urban Uganda
REFNo: HS974ES

1. To assess the effect of the combined food literacy and physical activity intervention on metabolic health (waist circumference, blood glucose; blood lipid profile – total cholesterol, HDL cholesterol and triglycerides; body composition and blood pressure) of WRA in urban Uganda 2. To assess the effect of the combined food literacy and physical activity intervention on moderate physical activity behavior among WRA in urban Uganda 3. To assess the effect of the combined food literacy and physical activity intervention on consumption of fruits and vegetables among WRA in urban Uganda 4. To assess the effect of the combined food literacy and physical activity intervention on the use of food, nutrition and physical activity information among WRA in urban Uganda
Uganda 2020-10-27 2023-10-27 Medical and Health Sciences Degree Award
Gloria Seruwagi Seruwagi
ID:
Adherence, Lived Experiences and Resilient Transformation among “slumdwellers” (ALERTs) in COVID-19: A study of Ki-Mombasa and Kabalagala-Kataba slums in Kampala
REFNo: SS555ES

General objective
We seek to study slum dwellers’ lived experiences, assess behavioural shifts and determine public compliance and social behaviour in light of COVID-19.
Specific objectives
1. To assess knowledge or awareness of COVID-19 and local perception of risk in urban slums. This will also capture infodemic issues, myths, fears, etc
2. To identify local pre-post COVID attitudes and practices relating to health and social norms. This will include e.g. WASH, healthseeking behaviour, community cohesion practices
3. To explore implementers’ interpretation and enforcement of COVID-19 guidelines. Implementers will include healthworkers, police, LDUs, politicians, etc
4. To determine the feasibility of, and adherence to, COVID-19 preventive measures.
Will include local interpretations, experiences, innovations, improvisations and explanatory factors
5. To identify community resources, systems and assess their efficacy in the COVID-19 response. This will cover essential systems & services including health, social care and community leadership


 Uganda 2020-10-26 2023-10-26 Social Science and Humanities Non-degree Award
Michael Olanya West
ID:
Head Teachers’ Views of their Instructional Leadership Practices; A Case Study of Four Primary School Head Teachers in Kitgum Municipal Council, Uganda
REFNo: SS568ES

a) To investigate how primary school head teachers in Kitgum Municipal Council perceive their instructional leadership practices
b) To find out head teachers’ understanding about instructional leadership practices
c) To find out factors which facilitate or hinder head teachers’ practice of instructional leadership
 Uganda 2020-10-26 2023-10-26 Social Science and Humanities Degree Award
JOAN KEMPANGO
ID:
“Assessment of Factors Associated with Acquisition of Clinical Competences Among Undergraduate Nursing Students in Ugandan Universities”
REFNo: HS639ES

1) To determine the involvement of clinical mentors in the undergraduate acquisition of clinical skills;
2) To investigate clinical mentors preparedness in facilitating undergraduate student’s clinical skills
3) To assess student perception of the learning environment in a clinical set-up among undergraduate nursing students in Uganda;
4) To identify the available learning resources for the acquisition of clinical skills among undergraduate nursing students in Uganda;
5) To establish the influence of institutional factors on competence acquisition by the undergraduate nurses in Uganda.
6) To establish the effect of student factors on clinical competence acquisition by the undergraduate nurses in Uganda.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Degree Award
Mary  Nanteza Bridget
ID:
Does recombination of polio viruses with locally circulating enteroviruses play a role in acute flaccid paralysis and vaccine-derived polioviruses?
REFNo: HS770ES

1. General Objective
To identify polio mutations that are common to AFP, and cVDPV cases.

2. Specific Objective
i) To determine if polio/non-polio recombination has occurred in AFP cases
ii) To characterize primary recombination events in the polio virus genome that are associated with AFP, and
iii) To compare the recombination events common in AFP with published cVDPVs and characterize the events that could be common in VDPVs.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
Munshi Sulaiman
ID:
Evaluation of the Disability-Inclusive Ultra-Poor Graduation Programme (DIG) in Uganda
REFNo: SS529ES

1. To estimate the impact of the Ultra-Poor Graduation programme on poverty, livelihood and social participation of people with disabilities and their families, compared to controls who do not receive the intervention.
2. To estimate the impact of the Ultra-Poor Graduation programme on poverty, livelihood and social participation of people with disabilities and their families, compared to people without disabilities who received the intervention
Bangladesh 2020-10-22 2023-10-22 Social Science and Humanities Non-degree Award
Cristina Clerici
ID:
The Parallel Pandemic of Domestic Violence Against Women in Uganda: is the Lockdown to Blame?
REFNo: SS553ES

Our project seeks to study the relationship between IPV and the relative economic conditions of spouses in Uganda, by exploiting the implementation of COVID-19 containment measures as a source of exogenous variation in the woman's relative income.
Italy 2020-10-22 2023-10-22 Social Science and Humanities Degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 PERCEPTIONS OF HEALTHCARE WORKERS REGARDING LOCAL INFECTION PREVENTION AND CONTROL PROCEDURES FOR COVID-19
REFNo: HS867ES

Primary aim: To better understand health care worker perceptions of infection prevention and control procedures to prevent Covid-19 transmission.

Objectives:
1. To evaluate healthcare worker perceptions of their preparedness to ensure effective infection prevention and control of Covid-19 in healthcare settings, and to evaluate healthcare worker’s level of trust in their healthcare organization/facility.

2. To consider how these factors vary
a. Across age, staff role, and length of clinical experience;
b. Between respondents whose hospital is receiving suspected/ confirmed patients and those whose hospitals are not;
c. Between those who have direct experience of treating Covid-19 patients and those who have not.
d. Across different regions in the country that have dealt with other epidemics other than COVID19.
e. Between countries in different global regions where this survey is conducted.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
Imran Rasul
ID:
Firm Dynamics and Worker Resilience to the COVID-19 Shock in Uganda
REFNo: SS565ES

The overall objective of this prpject is to study the effects of the Covid-19 shock on SMEs and workers in Uganda. The study will aim at answering the following research questions:
1. What firm-level characteristics predict firm survival and growth in an expansionary business cycle? Do the same characteristics predict firm resilience to the shock of COVID-19?
2. How do markets evolve during periods of economic growth, in terms of the number of firms, firm size distribution, and level of competition? How does the COVID shock affect the structure and level of competition within markets?
3. How do different types of skills training affect workers’ resilience to the economic shock caused by COVID-19?

 UK 2020-10-22 2023-10-22 Social Science and Humanities Non-degree Award
Fred Wabwire-Mangen
ID: UNCST-2021-R013549
 Assessing the Burden of Asymptomatic SARS-COV-2 Infection among Patients Seeking Health Care at Health care facilities in Uganda
REFNo: HS889ES

To determine the prevalence of SARS-CoV-2 among a sample of patients seeking health care and HCWs at participating surveillance sites who do not meet the case definition for COVID-19.
 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
ANNETTEE NAKIMULI OLIVIA
ID: UNCST-2022-R011194
 In-depth case study of large referral maternity wards in four countries in sub-Saharan Africa: a case study of Kawempe National Referral Hospital and Mulago Specialized Women and Neonatal Hospital in Uganda
REFNo: HS907ES

1) To document the preparedness and response to COVID-19 among large maternity/newborn wards in four countries in sub-Saharan Africa over time
2) To serve as a platform for exchange of information and experiences across the contexts studied.

 Uganda 2020-10-22 2023-10-22 Medical and Health Sciences Non-degree Award
Joyce Kambugu Balagadde
ID: UNCST-2020-R014996
 A regional approach to improved childhood cancer drug access in East Africa: Understanding access and coordinating procurement
REFNo: HS681ES

1. Undertake detailed institutional and health system data collection to obtain key metrics of drug availability and price in participating jurisdictions 2. Describe policies and practices related to childhood cancer drug procurement and provision in partner jurisdictions 3. Analyse the key determinants of childhood cancer drug access in the health system context 4. In partnership with national governments, establish agreements and mechanisms for coordinated procurement of essential childhood cancer medicines, based on evidence-based estimates of need.
Uganda 2020-10-21 2023-10-21 Medical and Health Sciences Non-degree Award
Brian Kanaahe Mwebaze
ID:
“Understanding And Addressing The Sexual Reproductive Health And Rights Needs Of Young Women And Girls In Humanitarian Settings In Nigeria And Uganda"
REFNo: SS611ES

1.Synthesize existing literature on the Sexual Reproductive Health and Rights challenges of young refugee women and girls, highlighting promising solutions and best practice service delivery models.
2.Conduct participatory, mixed methods formative research to generate evidence on the Sexual Reproductive Health and Rights knowledge and challenges of young women and girls in the target refugee settings.
3.Assess existing service provision models against global standards and best practice guidelines for adolescent/youth friendly Sexual Reproductive Health and Rights services in humanitarian settings with a comparison between refugees and Internally Displaced Persons (IDPs).
4.Support existing Sexual Reproductive Health and Rights initiatives in refugee camps in the target countries to use emerging evidence to improve advocacy for, demand for, and provision of Sexual Reproductive Health and Rights services for adolescent girls.
 Uganda 2020-10-21 2023-10-21 Social Science and Humanities Non-degree Award
Harriet Mpairwe
ID: UNCST-2025-R017439
 Psychosocial well-being and urbanisation among adults in Uganda: A pilot study
REFNo: HS831ES

1. To assess the feasibility of collecting data on psychosocial factors among adults in urban (Kampala) and rural (Mpigi and Wakiso) Uganda
2. To establish the hair cortisol concentration assay in our immunology laboratory
3. To assess the acceptability of scalp hair sample collection for research purposes

 Uganda 2020-10-19 2023-10-19 Medical and Health Sciences Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4STEM: A signature program to advance STEM education in Africa
REFNo: SS475ES

Objective 1. Test the feasibility, acceptability, and preliminary impact of innovative Suubi4STEM intervention in promoting educational STEM opportunities and life options for young people in Uganda.

Objective 2. Qualitatively examine participants’ and facilitators’ intervention experiences and identify individual, family and institutional-level facilitators and barriers to Suubi4STEM intervention implementation and participation. Objective 3. Evaluate the cost of implementing Suubi4STEM. Objective4. Disseminate program findings to promote the Suubi4STEM intervention on a larger scale

 Uganda 2020-10-16 2023-10-16 Social Science and Humanities Non-degree Award
Mandela Wangoola Robert
ID:
FACTORS INFLUENCING TRYPANOSOMA BRUCEI RHODESIENSE STABILITY IN CATTLE RESERVOIR IN LANGO SUB REGION
REFNo: NS135ES

General Objective
• Evaluate the factors influencing Trypanosoma brucei rhodesiense infections persistence and stability in the cattle reservoir in Lango sub region
Specific objectives
(i) To determine the prevalence of bovine trypanosomiasis in Lango sub region.
(ii) Assess the stability of T. b rhodesiense in naturally infected cattle in Lango sub region
(iii) Evaluate risk factors leading to continued cattle trypanosomiasis infection in Lango sub region

 Uganda 2020-10-16 2023-10-16 Natural Sciences Degree Award
Sara Nsibirwa
ID: UNCST-2021-R012889
 Antimicrobial resistance in trauma and burn patients with blood stream or wound infections – an observational cohort study from Kampala, Uganda
REFNo: HS815ES

The primary aims:
• To determine the prevalence of blood stream due to specific bacterial and fungal pathogens resistant to first choice empirical treatment in trauma and burn patients.
• To determine the prevalence of wound infections due to bacterial and fungal pathogens resistant to first choice empirical treatment in trauma and burn patients
The secondary aims:
• To describe the proportion of burns and trauma patients requiring a switch of antibiotic or antifungal treatment following wound swab and blood culture results.
• To describe the clinical outcomes of trauma and burn patients with blood stream and wound infections due to bacterial and fungal pathogens resistant to first choice empirical treatment
• To identify risk factors for the development of wound and blood stream infections due to resistant bacterial and fungal pathogens among trauma and burn patients.


Uganda 2020-10-15 2023-10-15 Medical and Health Sciences Non-degree Award
Emmanuel Gusango Humphrey
ID:
Constructivist informed teaching and preparation of students in Primary Teachers Colleges of South Eastern Region in Uganda
REFNo: SS498ES

i. Explore the constructivist principles used in the instruction of students in Primary Teachers Colleges.
ii. Examine the constructivist practices applied to the school practice supervisory process in Primary Teachers Colleges.
iii. Examine the implementation of coaching in the preparation of students’ professional growth.

Uganda 2020-10-14 2023-10-14 Social Science and Humanities Degree Award
Robert Tweyongyere
ID:
Optimizing SMART Dairy Technologies for Efficient Sustainable Productivity of Dairy Farmers in Uganda
REFNo: A80ES

Specific objectives
1. Determine the dairying problems and constraints, current solution options and priority list of solutions which are gender sensitive across age and space.
2. Determine the dairy farmers’ cattle feeding and breeding practices in the milk sheds of Uganda
3. Determine local feed ingredients nutrient profile for optimal dairy feed ration formulation
4. Develop a farmers’ community based breeding program
5. Increase Farmers’ access to elite genetics by artificial breeding technologies (artificial insemination(AI) and Embryo transfer(ET))
6. Determine the nutritional-metabolic profiles among the dairy cattle in selected DaFaN clusters to Optimize cost-effective forage production, preservation and utilization
7. Determine animal health and breeding profile parameters generated by ruminal or collar sensor technology for effective monitoring of individual animals on farms in Uganda

 Uganda 2020-10-14 2023-10-14 Agricultural Sciences Non-degree Award
Robert Newton Edward
ID: UNCST-2023-R006537
 Community surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and of coronavirus disease-2019 (COVID-19) in high risk and general populations.
REFNo: HS823ES

1. To measure the changing incidence and prevalence of SARS-CoV-2 over time and, associated mortality. 2. To assess the impact of co-morbidities on acquisition and survival of SARS-CoV-2. 3. To examine in greater depth the public understanding of COVID-19 and the experience of the surveillance exercise.
UK 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Robert Tweyongyere
ID:
EFFECTIVENESS OF ANTHELMINTICS IN CATTLE AND GOATS IN MIXED FARMING COMMUNITIES IN MBARARA, KIRUHURA SEMBABULE AND NAKASONGOLA DISTRICTS
REFNo: A83ES

General Objective:
To assess effectiveness of dewormers and generate information that would support decision on improving management of anthelmintics in Uganda

Specific objectives:
1. To document the knowledge, attitude and deworming practices of selected livestock farmers in Mbarara, Kiruhura, Sembabule and Nakasongola districts
2. Determine the worm burden among cattle and goats on the selected farms
3. To determine the ‘clinical efficacy’ of five identified dewormers commonly available to the farmers

Uganda 2020-10-14 2023-10-14 Agricultural Sciences Non-degree Award
Simon Peter Kibira Peter Sebina
ID: UNCST-2019-R000492
 Improving quarantine in Uganda as a key measure to combat COVID-19: Compliance, experiences, gaps and opportunities
REFNo: HS832ES

1. To determine compliance with COVID-19 quarantine measures among self and institutional quarantined persons in Uganda.

2. To determine factors associated with compliance with COVID-19 quarantine measures among self and institutional quarantined persons in Uganda.

3. To explore experiences and coping mechanisms among self and institutional quarantined persons in Uganda.

4. To identify gaps in the management and opportunities for improvement of the quarantine process in Uganda.
 

 Uganda 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 A multicenter, phase III, double-blind, randomised, active-controlled study to evaluate the efficacy and safety of VPM1002 in comparison to BCG in prevention of Mycobacterium tuberculosis infection in newborn infants
REFNo: HS838ES

Primary objectives
1. To demonstrate that VPM1002 is non-inferior to BCG SII in providing protection against incident Mtb infection
2. To demonstrate that vaccination with VPM1002 is superior to BCG SII in providing protection against incident Mtb infection

Secondary objectives
1. To compare the safety and tolerability profile of VPM1002 and BCG SII administered as a single dose to newborn infants
2. To compare the protective efficacy of VPM1002 versus BCG SII against TB disease
3. To compare the protective efficacy of VPM1002 versus BCG SII against sustained Mtb infection

Exploratory objectives
1. To evaluate the immunological response to vaccination with a single dose of VPM1002 compared to BCG SII in a subset (immunogenicity cohort) of HIV-exposed and HIV-unexposed newborn infants in terms of the following parameters:
o Concentration of Interferon (IFN)-γ in the supernatant after antigen re-stimulation as determined by ELISA
o CD4+ and CD8+ T-cells after antigen stimulation as determined by Fluorescence-activated cell staining/Intracellular cytokine staining (FACS/ICS)
o Transcriptomics
o Antibody production
2. To evaluate occurrence of QuantiFERON® Gold Plus In-tube test (QFT) conversion, where conversion is defined using alternative QFT thresholds (e.g. > 4 IU/ml); and sustained QFT conversion, where sustained conversion is defined as QFT ≥ 4IU /ml maintained for approximately 6 months following initial QFT conversion, compared across trial arms in all participants.
3. To determine the mortality rate in children receiving VPM1002 compared to BCG SII

Uganda 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Victoria Nankabirwa
ID: UNCST-2021-R011871
 SARS-CoV-2 infection and COVID-19 in women and their infants in Kampala, Uganda
REFNo: HS915ES

Overall aim
To describe how the COVID-19 epidemic and Uganda's countermeasures affect women and their newborns, especially newborns of HIV-1 positive mothers, and to test whether BCG vaccination offers protection against SARS-CoV-2 infection and COVID-19.

Specific objectives
1. To investigate if BCG vaccination of HIV-1 exposed infants at birth or at 14 weeks of age protects them against SARS-CoV-2 infection and COVID-19 until 14 weeks of age or against COVID-19 between 15 and 52 weeks of age, respectively.
2. To estimate the evolving prevalence of SARS-CoV-2 infection and of COVID-19 among HIV-1 positive as well as among HIV-1 negative women who have recently given birth, and describe their association with hospitalization on the day of birth, complications during delivery, low birth weight, and other adverse outcomes
3. To estimate the evolving 14-week cumulative incidence of SARS-CoV-2 infection and of COVID-19 among mothers and babies, and evaluate whether maternal HIV-1 infection affects maternal and infant risk of developing COVID-19 of varying severity
4. To evaluate the impact of wide-ranging preventive measures to control COVID-19 on women giving birth during the epidemic, their children, and their families

 Uganda 2020-10-14 2023-10-14 Medical and Health Sciences Non-degree Award
Emanuel  Peter L
ID:
Development of Standardized Herbal Formulation: Synergy between Momordica charantia, Aloe vera and Abelmoschus esculentus for Glycemic Control
REFNo: NS119ES

Objectives
1. To establish ethnomedical use of M. charantia and A. esculentus among indigenous community in Tanzania.
2.To establish physicochemical and stability parameters of freeze dried aqueous extracts of the three plant species separately in pre-formulation studies.
3. To evaluate efficacy of combined freeze dried extracts in different ratios of doses of M. charantia, A. esculentus and A. vera in vivo.
4. To establish safety profile of best optimal dose combination of M. charantia, A. esculentus and A. vera on healthy Wistar female rats.
5. To design a solid pharmaceutical dosage form of the optimal dose combination and evaluate its stability, safety and efficacy in vivo.

Tanzania 2020-10-12 2023-10-12 Natural Sciences Degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS