Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
ANN AKITENG ROSE
ID: UNCST-2025-R019916
Assessing Healthcare Barriers and Identifying Implementation Strategies to Mitigate Cardiovascular Risks Among Market Vendors in Urban Markets in Kampala and Mbarara, Uganda
REFNo: HS6472ES

The aim of this study is to generate formative quantitative data on the health status, cardiovascular disease (CVD) risk factors, daily routines, and healthcare access and barriers of market vendors in Uganda in order to identify opportunities for culturally appropriate and feasible lifestyle modification interventions and potential implementation strategies to reduce CVD risk.
Uganda 2025-10-08 18:59:30 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PATIENCE AYESIGA
ID: UNCST-2023-R003499
The implications of wetland dynamics on water qiuality for conservation of Rwizi macro catchment south western Uganda
REFNo: SS4498ES

To characterize the spatial-temporal dynamics and explore drivers of wetland degradation for middle Rwizi catchment. 2.To assess the implications of wetland degradation on sediment for middle Rwizi catchment. 3.To analyze the influence of nutrients on water quality for middle Rwizi catchment. 4.To evaluate the effectiveness of existing conservation develop suitable restoration and conservation mechanisms for improved catchment health of middle Rwizi system.
Uganda 2025-10-08 18:58:01 2028-10-08 Social Science and Humanities Degree Award
Obondo Sande James
ID: UNCST-2019-R000241
Effect of Mycobacterium tuberculosis and its cell wall glycolipids on the HIV Reservoir in CD4+ T cells
REFNo: HS5439ES

1. To determine if MTB molecules (e.g. PIM6, LAM, MTB lysate) induce HIV expression in memory CD4+ T cells from ART-suppressed HIV infected persons.

2. To determine the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB compared to HIV infected individuals with history of documented treated TB, LTBI, and no LTBI (HIV-monoinfected).

3. To assess longitudinal changes in the size of peripheral HIV reservoir in memory CD4+ T cells in HIV infected individuals with active TB before initiation of TB treatment and at the end of treatment

Uganda 2025-10-08 18:16:22 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kansiime Cecilia
ID: UNCST-2025-R017890
OPTIMIZATION OF THE REARING SUBSTRATES FOR BLACK SOLDIER FLY LARVAE AND ITS ACCEPTABILITY AS AN ALTERNATIVE PROTEIN SOURCE AMONG POULTRY FARMERS IN THE RWENZORI REGION
REFNo: A647ES

(i) To determine the appropriate growing substrates for black soldier fly larvae as a source of protein for poultry. (ii) To assess farmers perceptions and acceptance of black soldier fly larvae as a source of protein for poultry. (iii) To determine the economic feasibility of using black soldier fly larvae as a source of protein for poultry.
Uganda 2025-10-08 13:11:23 2028-10-08 Agricultural Sciences Non-Clinical Trial Degree Award
Richard Selwanga
ID: UNCST-2025-R018576
THE EVOLUTION OF THE LINGUISTIC LANDSCAPE OF KAMPALA: LANGUAGE POLICY, MULTILINGUALISM, AND PUBLIC PERCEPTIONS
REFNo: SS4333ES

(i) To examine the language of public signs in the LL Kampala District from the colonial to post-colonial period. (ii) To analyse the impact of language policies on language visibility in the LL of Kampala District from the colonial to post-colonial period. (iii) To investigate the role that multilingualism has played in shaping the LL of Kampala District from the colonial to post-colonial period. (iv) To explore the perceptions of the target readership towards language use in the contemporary LL of Kampala District.
Uganda 2025-10-08 13:06:29 2028-10-08 Social Science and Humanities Non-Clinical Trial Degree Award
Mulebeke Ronald
ID: UNCST-2025-R017304
IMPLEMENTATION AND ASSESSMENT OF THE THRIVE PROJECT; STRENGTHENING MENTAL HEALTH AND SOCIOECONOMIC RESILIENCE AMONG YOUTH LIVING WITH HIV IN WAKISO DISTRICT, UGANDA
REFNo: HS6493ES

1. To conduct a gap assessment of the current mental health services for youth living with HIV in Wakiso District.

2. To explore the structural, social and policy related barriers to effective integration of mental health services into HIV care for YLWH in Wakiso District.

3. To explore the structural, social and policy related facilitators to effective integration of mental health services into HIV care for YLWH in Wakiso District.
4. To assess the feasibility of integrating Group Support Psychotherapy training in improving mental health outcomes among YLWH at Mildmay Uganda Hospital in Wakiso District.
5. To assess the feasibility of economic empowerment in improving mental health outcomes among YLWH seeking care at Mildmay Uganda Hospital in Wakiso District.
6. To conduct a process evaluation of the THRIVE project among YLWH at Mildmay Uganda Hospital in Wakiso District.

Uganda 2025-10-08 11:21:31 2028-10-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert MPIIRA
ID: UNCST-2022-R005391
Community Engagement and Access to Services Related to Gender-Based Violence and Sexual Reproductive Health and Rights in Uganda: A Qualitative Study
REFNo: SS4367ES

● Do male influencers view themselves as agents of change (or potential agents of chance) for AGYW? Can they be adequately motivated to serve as champions or advocates for AGYW rights, and if so, what would incentivize them to play that role most effectively?,● What role do YDCs or other community-based support groups/networks play in supporting AGYW\'s social and economic empowerment, as well as the long-term sustainability of interventions?,● What are the current service gaps in SRHR and GBV within the targeted communities? What institutional or system-strengthening support is needed to address these gaps and improve the effectiveness of referrals?,● What are the main barriers associated with discussing SRHR and GBV topics with family members and men toward shifting social norms and what strategies can help effectively mitigate these barriers?,● What are the key barriers and enablers faced by the AIM 2.0 programme in influencing existing community structures, particularly informal structures, to improve the socio-economic conditions and empowerment for AGYWs?,To ensure the implementers fully understand the contexts where they are working and if necessary adapt the implementation activities through more enhanced community engagement in order to improve access to services for AGYW, particularly SRHR and GBV protection. ,
Uganda 2025-10-07 10:35:55 2028-10-07 Social Science and Humanities Non-degree Award
Musa Sekikubo
ID: UNCST-2021-R014010
Congenital and Maternal Point of care Rapid Testing for Syphilis Study, Uganda (COMPARTS)
REFNo: HS6397ES

Main Objective: Conduct a pilot study of the reformulated Dual Path Platform (DPP) Syphilis Test and Treat (TnT) and Congenital Syphilis (CS) test, manufactured by Chembio, for a cohort of mother-baby pairs from Uganda.


Specific Objectives
a) Assess treponemal and non-treponemal antibody levels in perinatal blood from mothers and compare these findings with IgM and IgG results from the DPP Syphilis TnT assay.

b) Assess treponemal and non-treponemal antibody levels in newborn and cord blood from paired babies and compare these findings with IgM and IgA results from the DPP Syphilis CS assay.

c) Determine the performance characteristics of the POC device by calculating the sensitivity, specificity, positive and negative predictive values, and the proportion of tests that return invalid results or errors.
Uganda 2025-10-07 10:25:59 2028-10-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patience Atukunda
ID: UNCST-2023-R005832
BUILDING ARTIFICIAL INTELLIGENCE MODELS FOR BREAST CANCER DIAGNOSIS USING CLINICAL, ULTRASOUND AND CYTOLOGY DATA
REFNo: SIR559ES

i To build and evaluate an Artificial Intelligence Model for prediction of breast cancer using clinical features ii To build and evaluate an Artificial Intelligence model for breast cancer diagnosis using ultrasound data iii To build and evaluate an Artificial Intelligence model for breast cancer diagnosis using cytology data iv To build and evaluate an Artificial Intelligence model to integrate clinical, radiology and pathology findings into one report
Uganda 2025-10-01 12:21:26 2028-10-01 Engineering and Technology Non-Clinical Trial Degree Award
Anne Akello Ruth
ID: UNCST-2022-R009131
ASSESSMENT OF OCCUPATIONAL HAZARDS AND HEALTH EFFECTS AMONG WORKERS OF GRAIN MILLS IN SOROTI CITY, UGANDA
REFNo: HS6278ES

1. To identify occupational hazards in work places within grain mills in Soroti city.
2. To establish knowledge, attitudes and practices (KAP)on occupational hazards among workers of grain mills in Soroti city.
3. To examine the status of implementation of OSH policies by owners and workers of the grain mills in Soroti city.
4. To determine the health effects of exposure to occupational hazards among workers of grain mills in Soroti city
5. To establish the factors that influence occurrence of occupational hazards and health effects among workers of grain mills in Soroti city.

Uganda 2025-10-01 12:20:18 2028-10-01 Medical and Health Sciences Non-Clinical Trial Degree Award
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