Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
MARGARET OYELA ONEGI
ID:
One-Year Post-Treatment Follow-up, Outcomes, and Determinants of Return Among Women Living with HIV Treated for Cervical Precancer in North Central Uganda
REFNo: HS7754ES

The overarching goal of this protocol is to evaluate one-year post-treatment follow-up rates, characterize clinical outcomes, and identify determinants of return among WLHIV treated for cervical precancer in North Central Uganda and the Primary Objectives are as follows:
a) To determine the proportion of WLHIV who return for the recommended one-year post-treatment rescreening after cervical precancer treatment.
b) To assess the clinical outcomes, such as persistent disease, among WLHIV who return for the one-year post-treatment rescreening.
c) To identify individual, clinical, and health system factors associated with returning for the one year post treatment rescreening among WLHIV

Uganda 2026-06-25 22:27:43 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
OCEN WALTER
ID: UNCST-2026-R024230
PERCEPTION OF COFFEE FARMERS ON THE DISTRIBUTION, MANAGEMENT AND EFFECTS OF DODDER WEED (CUSCUTA REFLEXA) ON COFFEE PRODUCTION IN LIRA DISTRICT, UGANDA.
REFNo: A777ES

1. To determine the farmers perception on the distribution and abundance of C. reflexa on coffee plantations. 2. To determine coffee farmers perception on management practices of C. reflexa 3. To determine coffee farmers risks that arise from C. reflexa infestation.
Uganda 2026-06-25 22:23:57 2029-06-25 Agricultural Sciences Non-Clinical Trial Degree Award
Dorothy Akongo
ID: UNCST-2023-R007564
Evaluating Essential Services provided by the Local Governments Using Citizen Report Card Endline Survey in Jinja, Uganda
REFNo: SS5329ES

1. To assess the citizens' knowledge and participation in the services provided by their local
government besides health.
2. To assess the community understanding and awareness of child focused health care and the right
of the child within the health care system
3. To explore health care providers’, children and community members understanding of child rights,
experiences and participation in health care received at health facilities and local government
Uganda 2026-06-25 22:22:13 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Andrew Walakira
ID: UNCST-2025-R022446
Combating Antimalarial Resistance: An AI-Driven Approach to Identify andPrioritize Key Parasite Mutations
REFNo: HS7367ES

1. To use AI-driven variant prediction, structural modeling, and clinical-epidemiological data integration to identify and prioritize Plasmodium falciparum mutations associated with drug and vaccine resistance.

2. To predict the pathogenicity of mutations across the P. falciparum genome.

3. To identify mutations located in active or functionally critical regions of prioritized P. falciparum genes by applying variant effect prediction and protein structure modeling tools.

4. To link predicted pathogenic mutations with available epidemiological and clinical metadata to identify variants of public health importance, including those associated with treatment failure, disease severity, or vaccine response.
Uganda 2026-06-25 22:18:53 2029-06-25 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
Evaluation of the Uzazi Salama Project on Healthy Pregnancies and Climate Resilience among Adolescent Girls and Young Women (AGYW) in Kasese district.
REFNo: SS5254ES

Primary objective:
To generate evidence on the maternal health journey of pregnant AGYW and assess health system readiness to provide quality maternal care and access health system readiness to provide quality maternal care for AGYWs in climate affected settings.
1. To assess health system readiness to provide quality youth friendly maternal health services for adolescence girls and young women in climate affected settings
2. To explore social cultural, economic and gender-related barriers influencing AGYWs access to sexual and reproductive health and maternal health services.
3. To document AGYW experiences using a journey mapping approach.
4. To assess the impact of climate related shocks (floods, landslides, droughts etc.) on access and utilization of maternal health services.
5. To identify health system challenges affecting quality of care and influence access to and utilization of maternal health care services among adolescent girls and young women (AGYWs).
6. To generate evidence to inform co design of climate resilient interventions

Uganda 2026-06-25 22:17:28 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Julius Monday Rude
ID: UNCST-2025-R019646
Transmission Dynamics, Risk Factors, and Clinical Outcomes of Monkeypox Virus in Uganda from 2024 to 2025
REFNo: HS7965ES

1. To identify the risk factors of MPXV infection in Central and Western Uganda between 2024 and 2025. 2. To assess the routes of transmission of MPXV infection among adults in Central and Western Uganda between 2024 and 2025. 3. To assess the clinical presentation of MPXV infection among hospitalized adults in Central and Western Uganda between 2024 and 2025. 4. To assess the clinical outcomes of MPXV infection among hospitalized adults in Central and Western Uganda between 2024 and 2025. 5. To explore the three-month post-recovery effects of MPXV infection based on experiences of adult survivors of Mpox in communities of Central and Western Uganda between 2024 and 2025.
Uganda 2026-06-25 22:15:25 2029-06-25 Medical and Health Sciences Non-Clinical Trial Degree Award
John Okumu Bismarck
ID: UNCST-2025-R021281
An Exploration of the Effect of the Lower Secondary Competency-Based Curriculum on Lifelong Learning in Acholi subregion, Northern Uganda
REFNo: SS5199ES

Purpose To generate context specific evidence on how the implementation of the Lower Secondary Competency Based Curriculum contributes to the development of Lifelong Learning competencies among learners in the Acholi sub-region, Northern Uganda Specific Objectives The study will be guided by the following objectives: 1. To explore the Competency-Based Curriculum teaching/learning practices that align to lifelong learning in lower secondary schools in Acholi sub-region of Northern Uganda 2. To assess the indicators of lifelong learning on the students engaged in Competency-Based Curriculum in Acholi Sub-region of Northern Uganda 3. To explore experiences of stakeholders (Headteachers, Directors of studies, teachers and students) with CBC policy implementation in lower secondary schools in Acholi sub-region of Northern Uganda. 4. To analyse challenges in the implementation of the Competency-Based Curriculum in lower secondary schools in Acholi sub-region of Northern Uganda.
Uganda 2026-06-25 22:11:20 2029-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Wandera Yusuf
ID: UNCST-2026-R024024
"GOVERNANCE PRACTICES, FINANCIAL LITERACY PROGRAMS, AND EQUITABLE MEMBER DEVELOPMENT IN RURAL UGANDA SACCOS"
REFNo: SS5278ES

1. To assess how the effectiveness of SACCO leadership and board governance influences equitable member development.
2. To evaluate the role of transparency and accountability in promoting trust and fair distribution on equitable member development.
3. To examine the extent to which member involvement in SACCO governance affects equitable member development.
4. To investigate the impact of adherence to SACCO governance internal controls and risk management on equitable member development.
5. To evaluate how financial literacy programs affect equitable member development.
6. To develop evidence-based policy recommendations aimed at strengthening governance practices and financial literacy frameworks to enhance equitable member development in rural Uganda SACCOs.

Uganda 2026-06-25 22:09:43 2029-06-25 Social Science and Humanities Non-Clinical Trial Degree Award
WINNIE ACHOLA STELLA
ID: UNCST-2026-R024263
IMPACT OF STONE QUARRYING ACTIVITIES ON AIR, WATER QUALITY AND ASSOCIATED SELF-REPORTED RESPIRATORY SYMPTOMS: A CASE STUDY OF TE-DAM STONE QUARRY SITE IN GULU CITY
REFNo: NS1272ES

1. To determine the concentrations of particulate matter (PM10 and PM2.5) at varying distances from selected stone quarry sites in Te-dam. 2. To determine the physicochemical parameters (pH, turbidity, total dissolved solids, total suspended solids, nitrates, nitrites, iron, and color) of the surface water near Te-Dam quarry site. 3. To assess the perceived respiratory and water related health effects associated with air and water quality deterioration resulting from stone quarrying activities on individuals around Te Dam.
Uganda 2026-06-25 22:04:22 2029-06-25 Natural Sciences Non-Clinical Trial Degree Award
BOSCO Opio
ID: UNCST-2026-R023988
Modelling Seasonal Variations and the Influence of Personal-Environmental characteristics on Malaria Risk: Evidence from Lira District
REFNo: NS1304ES

Main Objective
To investigate the seasonal variations in malaria incidence and assess the influence of personal and
environmental characteristics on malaria risk in Lira District.
1.3.1 Specific Objectives
1. To Examine the seasonal variations of Malaria incidence in Lira district.
2.To Determine the influence of personal and environmental factors on the risk of malaria among
individuals in Lira District.
3. To Establish a suitable model to predict malaria risk in Lira district.
Uganda 2026-06-25 22:02:25 2029-06-25 Natural Sciences Non-Clinical Trial Degree Award
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