Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Anxious   Niwaha Jackson.
ID: UNCST-2023-R008010
Patho-physiologic and metabolic characterisation of Lean Diabetes in Uganda (LEAN-D study)
REFNo: HS4533ES

1. To establish the principal cause of hyperglycemia in lean SSA diabetes. (Hyperglycemia is high blood sugar)
2. To determine the association between biomarkers of beta cell function, and body composition and lean type 2 diabetes.
3. To establish if Persistent Organic Pollutants are present in sufficient levels in individuals with lean SSA diabetes to contribute to the process of developing diabetes.
4. To translate knowledge products into formats that are accessible and usable by key stake holders to enhance lean diabetes diagnosis, and inform policy and intervention strategies.

Uganda 2024-07-15 8:24:33 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Allan Kalungi
ID: UNCST-2022-R009843
Genetic, Biological and Psychosocial predictors of Incident and Persistent Internalizing Mental Disorders among Ugandan Children and Adolescents living with HIV: A Machine Learning Approach.
REFNo: HS4521ES

1. To build a machine learning model for prediction of prevalent, incident, and persistent cases of Internalizing Mental Disorders among Ugandan children and adolescents living with HIV.
2. To evaluate the performance of the machine learning model (developed in 1 above) based on each of genetic, biological, and psychosocial factors respectively.
3. To evaluate the performance of the machine learning model based on the combination all the three factor domains of genetic, biological, and psychosocial factors.

Uganda 2024-07-15 8:22:11 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Advancing Vaccine Development: Harnessing Multiple Antigenic Epitopes for Crimean-Congo Hemorrhagic Fever in Humans and Animals
REFNo: HS4493ES

Overall objective To develop and evaluate an adenovector CCHFV vaccine candidate. Sub-study general objectives i) To design the CCHFV immunogens and construct an adenovector CCHF vaccine candidate by conjugating the immunogens into the adenovector backbone. ii) To conduct preclinical studies of the CCHF vaccine in mice and non-human primates (animal models). iii) To translate knowledge products into formats that are accessible and usable by key stakeholders to enhance CCHF vaccine discovery and scale up.
Uganda 2024-07-15 8:16:36 2027-07-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jolly  Kamugisha G.K.
ID: UNCST-2023-R005715
Evaluation of The Early Childhood Nutrition Programme In The Karamoja Region, Uganda. RefNo: JCRC-2024-78:
REFNo: HS4490ES

To assess ECD centre readiness to implement integrated early childhood nutrition interventions in order to inform programming that fosters early childhood development in the Karamoja regionTo determine the early childhood developmental status of children aged 0-24 months in the Karamoja region. To determine the contextual barriers and facilitators to implementation of comprehensive nutrition interventions in ECD centres and their catchment communities in the Karamoja region To determine the effect of comprehensive early childhood nutrition interventions on Early Childhood Developmental status among children aged 24-59 months in the Karamoja region
Uganda 2024-07-12 14:50:24 2027-07-12 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mamerito Nturanabo
ID: UNCST-2024-R004377
Social Equity Interventions and Maternal health outcomes in Bugiri District, Eastern Uganda
REFNo: SS2781ES

To establish the effect of legislation on the maternal Health in Bugiri District, Eastern Uganda,To establish the civic education effect on maternal health in Bugiri District, Eastern Uganda.,To establish Health provision effect on maternal health in Bugiri District, Eastern Uganda,To assess the relationship between social equity interventions and maternal health outcomes in Bugiri District, Eastern Uganda.,
Uganda 2024-07-10 13:41:35 2027-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
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