Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Nicholus Nanyeenya
ID:
Infection Prevention and Control (IPC): Profiling, Barriers, Facilitators and Effectiveness of an IPC Community-of-Practice in Central Uganda
REFNo: HS4570ES

The objectives are to;
a) Characterize the uptake of IPC measures in selected health facilities in Central Uganda
b) Explore the facilitators and barriers to the uptake of IPC measures in selected health facilities in Central Uganda
c) Determine the effectiveness of an IPC community-of-practice, using peer-to-peer mentorships in enhancing the uptake of IPC measures in Central Uganda.

Uganda 2024-07-22 12:12:29 2027-07-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Grace Kisitu Paul
ID: UNCST-2024-R004102
UNIVERSAL1: Pharmacokinetic study of an optimized dose ratio of dolutegravir/emtricitabine/tenofovir alafenamide fumarate: expediting a UNIVERSAL first line regimen for all children living with HIV in Africa
REFNo: HS4280ES

Primary objective:
To evaluate the pharmacokinetics and short-term safety of DTG and FTC/TAF administered to children living with HIV using a novel dose ratio

Secondary objective:
To evaluate the short-term efficacy of DTG and FTC/TAF
formulations in children using a novel dose ratio

Uganda 2024-07-19 3:45:20 2027-07-19 Medical and Health Sciences Clinical Trial Non-degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
PROMOTING MENTAL HEALTH OF TEACHERS AND CAREGIVERS USING A PERSONALIZED MHEALTH TOOLKIT IN UGANDA
REFNo: HS4431ES

3. To examine feasibility of mWEL-T and mWEL-P with parents and teachers from urban and rural regions (including examining feasibility of the implementation procedures and intervention efficacy) (n=160, 80 parents and 80 teachers from urban and rural regions).,To conduct a user-centered testing study to optimize usability of the Teacher and Parent versions of mWEL- mWEL-T and mWEL-P,1. To build a school system capacity (by establishing a cross-discipline digital health leadership & learning collaborative (n=10) and training a group of peer-community health workers (P-CHW) (n=30; 15 peer teachers and 15 peer parents) to implement the mWEL that is developed,The aim of the study is to test mWEL a newly developed mobile app and user-engagement strategies for mental health management and promotion targeting teachers and parents,
Uganda 2024-07-17 14:03:01 2027-07-17 Medical and Health Sciences Clinical Trial Non-degree Award
Emmanuel Musisi
ID: UNCST-2020-R004472
Assessing feasibility, acceptability and utility of Tuberculosis-Molecular Bacterial Load Assay for monitoring TB treatment in three HIV clinics in Kampala
REFNo: HS4475ES

iii. To innovate and describe a shortened RNA extraction protocol that will contribute to the reduction of the overall turn-around time of the TB-MBLA. This objective will support Ms. Kasinga Sharifah’s MSc in Molecular Biology at Makerere University. ,ii. Acquire knowledge about the adoptability, acceptability, feasibility, compatibility, satisfaction, and complexity of including TB-MBLA in routine TB care. This will be achieved through conducting end-of-study key informant interviews (KIIs), focus group discussions (FGDs), and surveys.,i. Understanding the baseline issues regarding the pathway to healthcare access, prior use of antibiotics and/or previous TB treatment, and socioeconomic status. This will be achieved by conducting a structured questionnaire study at different medical clinics around Kampala.,The overall objective of this study is to assess the feasibility, acceptability, and utility of the Tuberculosis-Molecular Bacterial Load Assay for monitoring TB treatment in three HIV clinics in Kampala and evaluate approaches that will reduce the turnaround time of the TB-MBLA assay.,
Uganda 2024-07-17 13:59:42 2027-07-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAMYENYA NAKITYO MARIAM
ID:
SELF-MANAGEMENT PRACTICES AND GLYCEMIC STATUS OF TYPE 2 DIABETES MELLITUS ADULT OUTPATIENTS ATTENDING THE DIABETES CLINIC AT KIRUDDU NATIONAL REFERRAL HOSPITAL
REFNo: HS4456ES

To determine the predictors of glycemic status among T2DM adult outpatients attending the diabetes clinic at KNRH.,To establish the relationship between self-management practices and glycemic status of T2DM adult outpatients attending the diabetes clinic at KNRH.,To evaluate the self-management practices of T2DM adult outpatients attending the diabetes clinic at KNRH.,To assess the glycemic status of T2DM adult outpatients attending the diabetes clinic at KNRH.,To investigate the self-management practices and the glycemic status of T2DM adult outpatients attending the diabetes clinic at KNRH.,
Uganda 2024-07-17 13:49:23 2027-07-17 Medical and Health Sciences Non-Clinical Trial Degree Award
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