Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Daphine Namara Arinaitwe Namara
ID:
The Risk of Diabetes and pre-Diabetes associated with use of Dolutegravir based Antiretroviral Therapy among adult persons living with HIV: A Case-control study at Mulago ISS clinic, Kampala, Uganda
REFNo: HS1077ES

Primary objective: To determine the risk of DM and pre-DM associated with the use of DTG-based ART among adult PLHIV at Mulago ISS Clinic.
Secondary objective; To determine other risk factors for DM and pre-DM among PLHIV adult PLHIV at Mulago ISS Clinic.

 Uganda 2021-02-09 2024-02-09 Medical and Health Sciences Non-degree Award
Christine Nalwadda Kayemba
ID: UNCST-2020-R014220
 A BASELINE ASSESMENT FOR THE ADVANCING SEXUAL REPRODUCTIVE HEALTH AND RIGHTS (ANSWER) PROGRAM IN THE WEST NILE AND ACHOLI SUBREGIONS IN UGANDA
REFNo: HS1079ES

General objective

To analyse the situation of sexual and reproductive health and rights (SRHR) aspects as well as GBV in the intervention districts of UNFPA’s programme targeting to advance SRHR in the Acholi and West Nile sub regions in Uganda, in order to generate scientific evidence that will inform evidence based planning, implementation and form a basis for monitoring and evaluation of the program interventions.

Specific objectives

1.To conduct Health facility assessment at targeted health facilities in West-Nile and Acholi sub regions in regards to offering quality equitable SRHR services (FP/Maternal health/Post abortion Care, HIV testing and Post GBV) that is responsive to the needs of women, girls, boys and men, refugees, and people with disabilities

2.To undertake an assessment of SRHR Knowledge, Attitudes and Practices (KAP) of adolescents and youth in school including refugees and people with disabilities from a sample of 1,800 targeted schools (primary & secondary) in the study districts on GBV and SRHR.

3.To conduct an assessment of SRHR Knowledge, Attitudes and Practices (KAP) of adolescents and youth out of school including refugees and people with disabilities in the study districts on GBV and SRHR.

4.To conduct a budget and expenditure analysis of key sectors at national level and the district local governments focusing on implementation of and accountability towards the demographic dividend priorities.
 Uganda 2021-02-09 2024-02-09 Medical and Health Sciences Non-degree Award
RUTH NAKATO
ID:
A model for assessing the Banking Sector Employees’ Ethical Behavior towards Cyber security.
REFNo: SIR34ES

1. To examine the extent to which cardinal virtue constructs can influence the cyber security behavioral intention of employees towards cyber security ethical behavior in commercial banks in Uganda. 2. To analyze the moderation effect of ethical climate on the virtue constructs in connection with the behavioral intention of employees towards cyber security ethical behavior in commercial banks in Uganda. 3. To examine the mediation effect of behavior intention on the influence of virtue ethics towards cyber security ethical behavior in commercial banks in Uganda. 4. To develop a model for assessing the Employees’ Ethical Commitment and Behavior towards Cyber security in commercial banks in Uganda. 5. To test and validate the developed model.
Uganda 2021-02-08 2024-02-08 Engineering and Technology Degree Award
Tadele Yadesa Mekuriya
ID: UNCST-2022-R010338
 Incidence, predictors and risk prediction of adverse drug reactions among inpatients 60 years and older at Mbarara Regional Referral Hospital, Mbarara, Uganda
REFNo: HS992ES

1. To determine the incidence and prevalence of ADRs among elderly inpatients at MRRH
2. To characterize (types, severity and preventability) the ADRs detected among elderly inpatients at MRRH
3. To determine the risk factors of ADRs among elderly inpatients at MRRH
4. To develop and validate an ADR risk score tool (to be named as PADR-HE) for elderly inpatients at MRRH
 Ethiopia 2021-02-08 2024-02-08 Medical and Health Sciences Degree Award
Angua Amis Mao
ID:
Energy access as a dividend for designing just transition pathways (EAJT)
REFNo: SIR48ES

1. To assess the effectiveness of different renewable energy technologies in accelerating green jobs creation and a low carbon trajectory; 2. To analyse the equity and distributional implications of energy transition in vulnerable communities across gender, age, and income groups;

3. To develop potential financial and business models to deliver a just transition pathway; and

4. To explore appropriate policy and regulatory frameworks required to support a just transition at multiple levels from grassroots to the national and regional level.

 Uganda 2021-02-08 2024-02-08 Engineering and Technology Non-degree Award
David Musoke
ID:
Distribution of antibiotic profiles and antibiotic resistance associated with tuberculosis treatment regimens from wastewater treatment plants in Africa
REFNo: HS1017ES

Specific objectives
1. To determine the profile and concentration of antibiotics used in TB treatment in raw and treated sewage.
2. To investigate the efficiency of the WWTP treatment process in relation to removal of antibiotics post chlorination.
3. To determine the prevalence of antibiotic resistant bacteria (ARB) in raw and treated wastewater in these WWTPs.
4. To evaluate the prevalence of antibiotic resistance genes (ARGs) in raw and treated wastewater.

 Uganda 2021-02-08 2024-02-08 Medical and Health Sciences Non-degree Award
Francis Ssali
ID: UNCST-2021-R012134
 An open-label, roll-over study with rilpivirine in combination with a background regimen containing other antiretrovirals (ARVs) in human immunodeficiency virus type 1 (HIV-1) infected subjects who participated in rilpivirine pediatric studies
REFNo: HS1083ES

In view of the primary objective of the study to provide continued access to RPV, no primary endpoint is defined for this study.Secondary Endpoint
The secondary endpoints are applicable for all subjects until data collection is terminated, as indicated.
Major Secondary Endpoints
The proportion of subjects experiencing adverse events (AEs) considered to be at least possibly related to RPV, AEs leading to discontinuation, serious adverse events (SAEs), pregnancies, and grade 3/4 rash regardless of causality throughout the study. Results of routine safety laboratory tests will only be collected if related to these types of AEs.
Other Secondary Endpoint
The proportion of subjects maintaining viral suppression (ie, <50 HIV-1 RNA copies/mL) based on available viral load data throughout the study. In case of virologic failure, emergence of resistance will also be evaluated based on available genotype/phenotype data.


 Uganda 2021-02-08 2024-02-08 Medical and Health Sciences Non-degree Award
Jonathan Mwiindi Thuranira
ID:
EMERGENCY CESAREAN SECTION AND LENGTH OF STAY IN HOSPITALS IN UGANDA
REFNo: HS1093ES

1. To determine if payer-type (SAFE vs. self-pay) is associated with the decision to delivery interval (DDI) for rural Uganda women undergoing an emergency C-section in Nyakibale Hospital and Rushoroza Hospital. The DDI is the first phase of the aggregated LOS. 2. To determine if payer-type (SAFE vs. self-pay) is associated with the aggregate LOS for rural Uganda women undergoing an emergency C-section in Nyakibale Hospital and Rushoroza Hospital in rural Uganda while adjusting for the Decision to Delivery Interval (DDI). 3. To describe the experience of eight young mothers (aged 18-25) having their second (or more) C-Section delivered by emergency C-section in Southwest Uganda under the SAFE program during April 2020.
 Kenya 2021-02-08 2024-02-08 Medical and Health Sciences Degree Award
Bonaventure Ssebyanzi Wasswa
ID:
PRIMARY SCHOOL SUPPORT SYSTEMS TO DEAF CHILDREN LEADING TO THEIR TRANSITION TO POST-PRIMARY EDUCATION IN UGANDA
REFNo: SS590ES

(i) To investigate the support systems for deaf children at the completion of primary school studies.
(ii) To examine the situation of deaf children at the completion of primary studies.
(iii) To explore the self of deaf children at the completion of primary studies.
(iv) To establish the strategies for transition to post-primary level of deaf children at the completion of primary studies.

Uganda 2021-02-05 2024-02-05 Social Science and Humanities Degree Award
Alex Taremwa Taremwa
ID: UNCST-2020-R014302
 VIABILITY OF DIGITAL SUBSCRIPTION IN EAST AFRICA – AN ANALYSIS OF VIUSASA AND CHIMPREPORTS’ PAYWALLS
REFNo: SS629ES

1. To identify critical success factors for subscription-based models in digital media platforms.
2. To establish the barriers to subscription uptake among digital media in East Africa.
3. To assess the critical success factors against the ChimpReports and Viusasa’s strategies.
4. To analyse the consumption habits of audiences in line with payment for digital content on Viusasa and Chimp.

Uganda 2021-02-05 2024-02-05 Social Science and Humanities Degree Award
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