Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
NAUME MUYANGA
ID:
UNDERSTANDING THE IMPACT OF GENDER BASED VIOLENCE ON HIV/AIDS PREVENTION AND TREATMENT HEALTH SEEKING BEHAVIORS AMONG TRANSWOMEN IN THE GREATER KAMPALA METROPOLITAN AREA, UGANDA.
REFNo: SS557ES

Broad objective:
To understand the impact of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Specific objectives:
1. To document the lived gender-based violence experiences among the transwomen in the greater Kampala metropolitan area, Uganda.
2. To explore the existing gender-based violence referral pathways used by the transwomen in the greater Kampala metropolitan area, Uganda.
3. To explore the impacts of gender-based violence on HIV/AIDS prevention and treatment seeking behaviors among the transwomen in the greater Kampala metropolitan area, Uganda.
4. To identify priority issues for advocacy and programming in prevention and response to gender-based violence among the transwomen in the greater Kampala metropolitan area, Uganda.

Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Susanna (Zanna) Clay
ID:
The origins of empathy- Investigating empathy development in the first two years of life
REFNo: SS596ES

Empathy – the sharing and understanding others’ emotions and thoughts – is an essential part of what it means to be human. While empathy underpins our most meaningful social interactions, we lack knowledge about its developmental and evolutionary origins. Thus far, research on empathy development remains limited, something which may have led to inaccurate conclusions that infants lack the capacity for empathy before their second year.. Although the view that infants lack empathy has recently been challenged, current research remains constrained by a lack of research attention as well as suitable methodologies to study early empathy. A key goal of this project is to address these limitations by conducting the first major study of empathy development across the first 2 years of life. By combining observations with novel experimental techniques our goal is study how the cognitive and affective components of empathy emerge.

Another objective is to investigate the impact that the social and cultural environment have on infant socio-emotional development. Research indicates that caregiving and the socio-cultural environment shape infant development, however, there is little research looking into how these factors shape empathy development. In addition, most developmental research so far has been conducted on infants from Western societies, also denoted as WEIRD (Western Educated Industrialised Rich Democratic) whilst ignoring cross-cultural variability. By focusing on a subset of Western societies, current developmental research is thus not representative of global diversity; ignoring insights from cross-cultural variation may lead to inaccurate interpretations.

In order to address this and understand how the socio-cultural environment shapes empathy development, it is essential to study how empathy develops in a more diverse cross-cultural sample. Through doing so, we can also address which aspects of empathy may be learned or socially-mediated, and which might reflect human universals. The current project aims to address this by studying the development of empathy and the influence of the socio-cultural environment. The capacity for empathy has far reaching consequences for how we function as a species and interact with others. A lack of capacity to care about others (empathy) can have many negative consequences for individuals and our societies, including reduced wellbeing, quality of social relationships, crime and mental health. Given the importance of empathy for our social and societal functioning, it is essential to know where empathy comes from and how it is shaped by social and cultural experiences.

This project represents a continuation and extension of the research activities of a current and approved research project, led by Professor Katie Slocombe, running on infant development in the Masindi district of Uganda. This project was approved by UNCST and UVRI (UVRI-045/2017). Our current project uses very similar methods and is planned to be conducted with the same local research assistants and communities who have participated in this research.

UK 2020-11-17 2023-11-17 Social Science and Humanities Degree Award
Kenneth Katumba Rogers
ID:
Developing a country-specific EQ-5D-5L value set and an inequality parameter for Uganda
REFNo: SS597ES

The primary objective of this study is to develop an EQ-5D value set for Uganda,

secondary objectives are:
● To explore the feasibility of a ‘lite’ valuation protocol in the LMIC setting
● To elicit a health inequality aversion parameter for Uganda
Uganda 2020-11-17 2023-11-17 Social Science and Humanities Non-degree Award
Doreen Nakimuli
ID: UNCST-2021-R013668
Understanding Self Injection of DMPA-SC: Provider Research Uganda 2020
REFNo: HS938ES

The study is aimed at gaining a deep understanding of the consumer and health care provider journey is critically important to the introduction of family planning products into new districts. through answering the following questions:
1. What is the value proposition of self-inject for them?
2. What would increase their level of trust in women’s ability to successfully self-inject?
3. What would enable them to support consumers on the self-injection journey?
o What would be included in an optimal consumer initial training experience?
o What factors would support them to provide ongoing support for consumers who inject at home and experience side-effects?
o How could they better help consumers overcome barriers to access, including ensuring stock of DPMA-SC for client’s re-supply of product?
4. What factors would optimize provider training for self-injection?
o How could training be more convenient, effective, and of higher perceived value?
o What are the opportunities and barriers to using digital channels to learn and attend training on self-inject?
o What are the opportunities and barriers to using digital channels to train and support clients in using self-inject?

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Theoretical analysis of the pediatric discharge process in Uganda: A process evaluation
REFNo: HS929ES

The primary objective of this study is to build a theoretical model of the current pediatric discharge pathway from the time of admission until post-discharge follow-up.
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
DAVID KATEETE PATRICK
ID: UNCST-2020-R004018
Co-infection of SARS-CoV-2 with M. tuberculosis & other respiratory pathogens (SARS-CoV-2-
REFNo: HS940ES

(1) Estimate the prevalence of coinfection of SARS-CoV-2 with other respiratory pathogens, (2) Investigate the impact of coinfections on molecular testing for COVID-19 infection and, (3) Apply metagenomics whole genome sequencing for unbiased detection of respiratory pathogens directly in respiratory samples
Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Dinah Amongin
ID: UNCST-2020-R014663
Rapid Assessment of COVID-19 Impact on Family Planning Access and Use
REFNo: HS952ES

1. Document the proportion of Viamo 3-2-1 users who have their demand for family planning satisfied by modern methods during the pandemic and the recovery process;
2. Measure the proportion of current modern contraceptive users who have obtained their preferred contraceptive method among women who initiated or resupplied their method during the pandemic and the recovery process;
3. Describe barriers in accessing family planning services to ensure voluntary method use and choice during the pandemic and the recovery process.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
International Registry of Healthcare Workers Exposed to COVID-19 Patients (UNITY Global) at Selected Health facilities in Uganda
REFNo: HS964ES

Primary Objective
To assess the association of potential prophylactic treatments with reduced risk of COVID-19 (or SARS-CoV-2 infection) in HCWs caring for COVID-19 patients at selected health facilities in Uganda.

Secondary objectives
i) To characterize the type of potential prophylactic treatments, by dose and duration, overall, and by region and or selected health facilities (sites) in Uganda.
ii) To explore the key factors (for example, use of PPE, HCW and healthcare facility characteristics, underlying co-morbidities, household history and COVID-19 exposure) modifying the risk of COVID-19 among HCWs at selected health facilities (sites) in Uganda.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
Margaret Lubwama
ID: UNCST-2019-R000636
Antibacterial activity of Rosmarinus officinalis L. and Curcuma longa against bacteria from clinical specimens in Uganda- A therapeutic option for multidrug resistant bacteria (ARC study)
REFNo: NS141ES

Main objective
To determine the activities of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts against bacteria isolated from clinical specimens at the Makerere University Microbiology Clinical Laboratory (MUCML) from January 2018 to December 2019

Specific objectives
1. To develop the chemical composition of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) extracts
2. To determine the Minimum Inhibitory Concentration of plant extracts from Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) against bacteria isolated from clinical specimens
3. To determine the synergistic effects of combination of Rosmarinus officinalis L. (rosemary) and Curcuma longa (turmeric) and antibiotics against bacteria isolated from clinical specimens in the MUCML
Uganda 2020-11-17 2023-11-17 Natural Sciences Non-degree Award
Wenceslaus Sseguya
ID: UNCST-2019-R000877
The Effect COVID-19 Pandemic on the Management and Control of Diabetes in Patients Receiving Support from a Life for a Child-Supported Diabetes Program in Kasese District, Western Uganda
REFNo: HS987ES

• To describe problems and challenges experienced by patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To explore personal experiences of health workers and primary caregivers regarding diabetes management and control of patients with insulin-requiring diabetes during the COVID-19 pandemic.
• To document mechanisms used to solve problems and overcome challenges encountered by patients with insulin-requiring diabetes, caregivers and health workers during the COVID-19 pandemic.
• To describe the perceived support needs for patients with insulin-requiring diabetes during the COVID-19 pandemic period and post the COVID-19 period.

Uganda 2020-11-17 2023-11-17 Medical and Health Sciences Non-degree Award
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