Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Mark Kaddu
ID: UNCST-2025-R017147
 IMPACT OF ELECTRONIC LOGISTICS MANAGEMENT INFORMATION SYSTEM (eLMIS) ADOPTION AND UTILIZATION ON SUPPLY CHAIN PERFORMANCE IN PUBLIC HEALTH FACILITIES IN GREATER KAMPALA METROPOLITAN AREA.
REFNo: HS5793ES

General Objective To assess the impact of eLMIS adoption and utilization on the performance of health supply chains in public health facilities in Greater Kampala Metropolitan Area Specific Objectives 1. To determine the level of adoption and utilization of eLMIS in public health facilities in Greater Kampala Metropolitan Area. 2. To investigate the impact of eLMIS adoption and utilisation on health supply chain key performance indicators in Greater Kampala Metropolitan Area public health facilities.
 Uganda 2025-06-05 9:11:13 2028-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Barbara Castelnuovo
ID: UNCST-2019-R000802
 HEALTHy aging with HIV in Uganda cohort: screening for non-communicable diseases and geriatric syndromes. (HEALTHiv)
REFNo: HS5803ES

Specific Aim 1. To document endpoints of NCDs (and their risk factors) that are common in older PLWH exposed to the currently recommended ART regimens, particularly cardio vascular disease, renal disease (proteinuria and creatinine clearance), metabolic syndromes and bone loss (calcaneal ultrasound) and their risk factors.
Specific Aim 2. To document frailty and other geriatric syndromes in older PLWH, frailty and geriatric syndromes progression and risk factors
Uganda 2025-06-05 9:08:20 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Maren Mickeler
ID: UNCST-2024-R003691
 Understanding supportive leadership in organizations
REFNo: SS3820ES

This study investigates how supportive leadership influences bottom-up knowledge sharing within organizations. Although frontline employees often have valuable insights, their knowledge frequently fails to reach upper management—often due to supervisory barriers such as strict hierarchies, micromanagement, or a lack of psychological safety.

To address this, the research team is conducting a randomized controlled trial (RCT) in collaboration with Centenary Bank Uganda. The intervention involves providing supportive leadership training to supervisors (middle managers) in randomly selected bank branches. Control branches will not receive the training during the study period.

Our main objective therefore is to test and measure the effect of supportive leadership training on bottom-up knowledge sharing and other organizational outcomes in a real-world organizational setting.
 Germany 2025-06-05 8:57:07 2028-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Paul Mwanja
ID: UNCST-2024-R002501
 ADMINISTRATIVE VARIABLES AND DISCIPLINE OF ACADEMIC STAFF IN PUBLIC UNIVERSITIES IN KAMPALA, UGANDA
REFNo: SS3830ES

i. To investigate the relationship between staffing and academic staff discipline in public universities in Kampala, Uganda.
ii. To examine the relationship between organizing and academic staff discipline in public universities in Kampala, Uganda.
iii. To analyse the relationship between directing and academic staff discipline in public universities in Kampala, Uganda.
iv. To assess the relationship between control and academic staff discipline in public universities in Kampala, Uganda.
v. To investigate the relationship between the intervening variables and academic staff discipline in public universities in Kampala, Uganda

 Uganda 2025-06-05 8:55:27 2028-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph Kirabira
ID: UNCST-2019-R001427
 A workshop-based learning for Medical Officers, Senior House Officers, Psychiatrists, and Pediatricians (Medical Doctors) in the use of medication in treating child and adolescent mental health conditions in Uganda.
REFNo: HS5877ES

Main Objective
1. To assess the current level of knowledge, skills, and practice of prescribing medications to address children and adolescents’ mental health conditions among medical doctors in Eastern Uganda.
2. To develop, evaluate and administer a workshop-based training materials on the use of medication in treating child and adolescent mental health conditions in Eastern Uganda.
Specific Objectives
1. To explore the knowledge, skills and practices of medical doctors regarding use of medications in treating child and adolescent mental health conditions in Eastern Uganda.
2. To develop and implement a workshop-based training for 50 medical doctors working with children and adolescents in Eastern Uganda.
3. To conduct an evaluation of the training programme among the medical doctors.
 Uganda 2025-06-05 8:49:35 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Cluster randomized trial of intermittent preventive treatment of malaria in school-age children to improve the health of students and decrease community transmission (CRITICal)
REFNo: HS5878ES

To estimate the effectiveness of IPTsc with DP in reducing community level malaria burden. We will test the hypothesis that malaria incidence will be lower in intervention clusters (randomised to receive IPTsc) than in control clusters (randomised to not receive IPTsc).
 Uganda 2025-06-05 8:47:33 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Amina Hassan
ID: UNCST-2025-R017065
 A STUDY OF CHILD MOTHERS’ EXPERIENCES ON COMMUNITY-BASED REHABILITATION IN MBALE DISTRICT, EASTERN UGANDA
REFNo: SS3834ES

Main objective/ purpose
The major objective of the study is to highlight the experiences of the child mothers' community-based rehabilitation services in Mbale District, Uganda.
Specific Objectives
1. To identify the challenges that the child mothers experience
2. To establish the support services they received from the community during pregnancy
3. To examine the support services they received from the community after delivery

 Uganda 2025-06-05 8:44:56 2028-06-05 Social Science and Humanities Non-Clinical Trial Non-degree Award
Aldomoro Burua
ID: UNCST-2024-R002082
 Characterization and treatment outcomes of asymptomatic pulmonary tuberculosis from community screening in Uganda
REFNo: HS5744ES

1) To assess the factors associated with asymptomatic compared with symptomatic pulmonary tuberculosis
2) To determine the infectiousness of asymptomatic compared with clinical pulmonary tuberculosis.
3) To evaluate the treatment outcomes of subclinical compared to clinical pulmonary tuberculosis.

 Uganda 2025-06-05 17:49:08 2028-06-05 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary Namukisa
ID: UNCST-2025-R016850
 PARTICIPANT COMPENSATION IN MEDICAL RESEARCH: PRACTICES AND PERSPECTIVES OF INVESTIGATORS AND RESEARCH ETHICS COMMITTEES IN UGANDA
REFNo: HS5901ES

1. To identify the factors influencing research compensation in medical research in Uganda.
2. To explore the perspectives of investigators and REC members regarding research compensation in medical research in Uganda.
3. To determine the common research compensation practices utilized in medical research conducted in Uganda.
 Uganda 2025-06-05 17:17:52 2028-06-05 Medical and Health Sciences Non-Clinical Trial Degree Award
Lorna Magara Florence
ID: UNCST-2025-R017918
 An Inquiry into the Phenomenon of Innovation Hubs in Uganda
REFNo: SS3976ES

1) To examine stakeholder perceptions and definitions of innovation hubs – Understanding how the founder, innovators, and university faculty conceptualize the role and function of innovation hubs within Uganda’s socio-economic context. 2) To identify the challenges and support mechanisms influencing stakeholder engagement – The study will assess the barriers and constraints that innovators, university faculty, and the founder face in their interactions with MoTIV, as well as the available resources that support innovation and entrepreneurship. 3) To analyze how collaboration influences the innovation culture at MoTIV Innovation Hub – The research will explore how partnerships among industry, academia, and government impact knowledge exchange, creativity, and technological advancement within the innovation hub.
Uganda 2025-06-05 17:04:33 2028-06-05 Social Science and Humanities Non-Clinical Trial Degree Award
Henry Ddungu
ID: UNCST-2019-R000966
 Feasibility and acceptability of red blood cell exchange among patients with sickle cell disease in Uganda.
REFNo: HS5971ES

1.To determine the availability and accessibility of RBCX in Uganda

2.To assess the willingness of patients with SCD to undergo therapeutic apheresis.

3. To evaluate the perceived benefits and drawbacks of therapeutic apheresis among patients with SCD.

4. To explore the potential barriers to the implementation and uptake of therapeutic apheresis in Uganda.
 Uganda 2025-06-02 17:42:17 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Steven  Puleh Sean
ID: UNCST-2021-R013722
 R21 MALARIA VACCINATION AMONG COMMUNITIES IN NORTHERN UGANDA DISTRICTS: UPTAKE, ADHERENCE TO SCHEDULE, ASSOCIATED FACTORS AND VACCINE EFFECTIVENESS
REFNo: HS5968ES

General objective To assess the uptake and adherence to vaccine schedules, associated factors, and the effectiveness of the R21 malaria vaccine in reducing test positivity rates, disease severity, and hospitalization rates among targeted children in selected communities in Northern Uganda. Specific objectives: 1. To assess the knowledge, attitude, and perceptions among communities of northern Uganda (Study I) 2. To assess the level of uptake (at least 1 dose) of malaria vaccine in children in children targeted for vaccination and its associated factors among communities in northern Uganda (Study II) 3. To evaluate adherence to the first three (3) malaria vaccine schedules for control of malaria in children under five years and associated factors in communities of northern Uganda (Study III) 4. To evaluate the effectiveness of malaria vaccine on test positivity rate, severity of the cases, mortality rates in the control of malaria one year after the introduction of the vaccine among children under five years in northern Uganda (Study IV)
Uganda 2025-06-02 17:40:17 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Annet Namusisi Mary
ID: UNCST-2025-R017592
 Evaluation of the Uganda Public Health Bulletin impact
REFNo: HS5978ES

1. Determine the reach of the UPHB among national, district, and international stakeholders 2. Explore how readers perceive the relevance, quality, and usefulness of the UPHB 3. Assess Content Quality Using Standardized Scorecards 4. Analyze trends in digital engagement as measured by email open rates, click-through rates, and website traffic over the past five years 5. Evaluate the impact of the UPHB on public health decision-making within 9 years of existence
Uganda 2025-06-02 17:38:50 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WALAKIRA FELIX JOSHUA
ID: UNCST-2023-R007993
 COMMUNITY PERCEPTIONS ON HERBAL MEDICINES USE IN TREATING UPPER RESPIRATORY INFECTIONS IN KATANGA SLUM, UGANDA; A WAY OF SPARING ANTIBIOTICS.
REFNo: HS5902ES

1. To explore prevailing perceptions and beliefs within the community regarding the efficacy of herbal medicines in treating upper respiratory infections.
2. To explore the perceived barriers and facilitators to the adoption of herbal medicines in treating Upper Respiratory Infections as a means of sparing antibiotics.
3. To determine the proportion of people in Katanga who have suffered from Upper Respiratory Infections.

 Uganda 2025-06-02 17:37:03 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Holly Parsons Jane Emily
ID: UNCST-2024-R002678
 Case Study: Exploring the Effectiveness of Village Health Teams in Uganda's 12 Refugee-Hosting District
REFNo: SS3874ES

The main objective on this research is to drive the narrative on a successful method of transition from humanitarian-funded to government ownership of health systems for refugees in low- and middle-income countries that depends on responsibility-sharing as part of the Global Compact on Refugees. The specific objective is to explore the effectiveness of Village Health Teams (VHTs) in Uganda's 12 refugee-hosting districts in preventing and treating human malaria by identifying key successes and key challenges of this health system, and then exploring how successes can be proliferated and how challenges can be mitigated.
Canada 2025-06-02 17:20:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Amon Tayebwa
ID: UNCST-2024-R002098
 THE ANATOMICAL VARIATIONS AND DISTRIBUTION OF THE HUMAN CORONARY ARTERIES: A CADAVERIC STUDY AT MBARARA REGIONAL REFERRAL HOSPITAL IN SOUTH WESTERN UGANDA.
REFNo: HS6003ES

1.What are the different branching and dominance patterns of the human coronary arteries amongst unclaimed bodies at Mbarara Regional Referral Hospital?
2.What are the different patterns of origin of coronary arteries at the sinotubular junction amongst unclaimed bodies at Mbarara Regional Referral Hospital?
 Uganda 2025-06-02 17:17:36 2028-06-02 Medical and Health Sciences Non-Clinical Trial Degree Award
Gloria Naome Aduku
ID: UNCST-2024-R015930
 IMPACT OF ANTHROPOGENIC ACTIVITIES (TOURISM) AND PARASITISM ON PHYSIOLOGIAL STRESS IN GORILLAS (Gorilla beringei beringei) IN BWINDI IMPENETRABLE NATIONAL PARK
REFNo: NS971ES

• To evaluate six different Enzyme Immunoassays (EIA) for quantifying fGCMs in mountain gorillas.
• To investigate the effect of bacterial metabolism and environmental factors on the stability of faecal glucocorticoid metabolite (fGCM) concentrations post-defaecation
• To examine variation in parasitic burden and fGCM concentrations of spatially separated mountain gorilla groups.
• To examine parasitic burden and fGCM concentrations of mountain gorillas during high and low tourism activity.
• To identify specific parasitic infections that correlate with elevated fGCM concentrations in mountain gorillas.

 Uganda 2025-06-02 17:16:50 2028-06-02 Natural Sciences Non-Clinical Trial Degree Award
AHEEBWA ROGGERS COLLINS
ID: UNCST-2025-R017036
 Tax Policies And Financial Performance Of Small & Medium Enterprises (SMEs) in Uganda: A Case Of SMEs in Kabale District
REFNo: SS3844ES

i. To examine the effect of tax compliance costs on the financial performance of small and medium enterprises in Kabale district
ii. To examine the effect of tax incentives on the financial performance of small and medium enterprises in Kabale district.
iii. To examine the effect of tax rates on the financial performance of small scale and medium enterprises in Kabale district.


 Uganda 2025-06-02 17:15:52 2028-06-02 Social Science and Humanities Non-Clinical Trial Degree Award
Kamya Moses
ID: UNCST-2020-R014203
 A case-control study to assess the effectiveness and safety of the R21/matrix-M malaria vaccine
REFNo: HS6009ES

To assess the Vaccine Effectiveness (VE) of R21/Matrix-M vaccine against severe malaria caused by Plasmodium falciparum.

To assess the Vaccine Effectiveness (VE) of the R21/Matrix-M vaccine against clinical malaria in high-transmission perennial areas caused by Plasmodium falciparum.

To assess if the R21/Matrix-M vaccine recipients are at an increased risk of death (all-cause).
 Uganda 2025-06-02 17:04:40 2028-06-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 PROTOCOL FOR THE PERFORMANCE EVALUATION OF ALINITY M HIV-1 ASSAY USING DRIED BLOOD SPOT SPECIMENS HIV VIRAL LOAD ASSAY FOR WHO PREQUALIFICATION ASSESSMENT
REFNo: HS6061ES

• To assess the Alinity m HIV-1 DBS assay’s agreement with a cobas HIV-1 Quantitative nucleic acid test for use on the cobas 6800/8800 Systems (Roche Diagnostics GmbH) on clinical specimens, including:
o Quantitative assessment of bias, limits of agreement and correlation
o Misclassification above or below the clinical threshold (1000 copies/mL)
• To assess the analytical performance of the Alinity m HIV-1 assay using DBS:
o Precision (repeatability and within-laboratory reproducibility)
o Linear range on the main subtypes
o Limit of detection
o Cross-contamination
• To describe the operational characteristics and ease of use of the Alinity m HIV-1 assay using DBS and its suitability for use in countries with limited infrastructure.

 Uganda 2025-05-29 17:20:17 2028-05-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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