Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Francis Kanyike
ID: UNCST-2024-R003739
Characterization Of HIV, Hepatitis B And C Patients’ Data Included Within The Joint Clinical Research Centre (JCRC) Clinical Database For Long Term Patient Outcome Evaluation
REFNo: HS5062ES

4. To characterize patients with current or previous HCV infection included in the dataset for demographics, visit frequency and clinical history.,3. To characterize patients with current or previous HBV infection included in the dataset for demographics, visit frequency and clinical history. ,2. To characterize patients living with HIV included in the dataset for demographics, visit frequency and clinical history,1. To characterize all JCRC patients included in the dataset for demographics, visit frequency and clinical history. ,
Uganda 2024-11-06 10:29:23 2027-11-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Michael Lubwama
ID: UNCST-2024-R002491
Sustainable Energy Systems for Refugee and host communities in Africa (SUNNY)
REFNo: SIR416ES

Main Objective
To gain insights into local contexts for SUNNY solutions’ implementation, define their use cases and technical requirements so as to ensure that further developments of the project reach the highest possible impact.

Specific Objectives
a) To determine the energy-related local conditions in Bidibidi refugee settlement and its local host community i.e., from a social, gender, cultural, economic, institutional, market, regulatory and environmental point of view.

b) To identify the local stakeholders, and their connections in Bidibidi refugee settlement specifying “key actors” that will be engaged in the MALLs (Multi-Act Learning Labs), regular participants in co-creation processes and end-users.

c) To determine the specifications, requirements and KPIs for use cases in Bidibidi refugee settlement and SUNNY tech. Solutions

Uganda 2024-11-06 10:26:43 2027-11-06 Engineering and Technology Non-Clinical Trial Non-degree Award
Phoebe Shambaugh Elise
ID: UNCST-2024-R003211
Children of War: Evolving mobilization and conceptions of child soldiering in Uganda, 1900-2000
REFNo: SS3296ES

This is one of the case studies of a larger UK Arts and Humanities Research Council grant. The research is comparative across time, region, forms of warfare and varying forms of child recruitment and military use across Africa, from the colonial period to approximately 2000, including archival and secondary data, and three focal case studies (Uganda, Angola, DRC). We are interested to both trace the evolution of child and youth involvement in armed conflict, and humanitarian and human rights responses to children in conflict which gave rise to the concept of 'child soldiers'.

The Uganda case study is critical to the project due to Uganda's centrality in humanitarian narratives and research on children in armed conflict over the last 30 years, as well as its interconnection with regional conflict dynamics (especially with Sudan/South Sudan, DRC and Rwanda). The Uganda case study intends to historicize and culturally-ground the concept of ‘child soldier’ which came to the fore in the 1990s and 2000s, and aims to trace the evolution of this concept and its relation to broader ideas of childhood and child labour in the colonial and post-colonial context. The case study therefore takes a wider temporal frame (1900-2000) than the overall grant project (1940-2000) to capitalise on Uganda’s rich history and archival sources. The specific objectives for the Uganda case study are:

To generate a historical dataset on the involvement of children and youth in armed conflict in Uganda, which will be analyzed comparatively across the other case contexts involved in the broader grant project;

To analyse the historical and regional diversity of ideas of childhood and youth across Uganda, and how these shape children and youth’s involvement in violence

To map (across time and space) humanitarian and local social responses to children/youth involvement and use in armed conflict, focusing on developing discourses and exchange/tension between local and global frames.

To develop connections to practitioners and networks working on child soldiers, DD[R]R (disarmament, demobilization, [rehabilitation], reintegration) and child/youth development across Uganda (both regionally and nationally)
USA 2024-11-06 10:24:17 2027-11-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Anahit Tevosyan
ID: UNCST-2024-R002668
Productive Business Loans for Women in Uganda: Evaluating the Impact of Large, Uncollateralized Loans
REFNo: SS3181ES

To quantify the impact of providing large, uncollateralized loans to women entrepreneurs. The power calculation (shown in the section later) confirms that with 1,000 treated and 1,000 control entrepreneurs, this study is powered at 80% to detect a 0.135 standard deviation (SD) effect on business profits, translating to an increase of approximately USD 64 per month, or 10% of the average borrower’s profits. To test if we can generate a credit scoring model to predict which women entrepreneurs will repay the loans and, relatedly, who will benefit from the loans. To understand if the provision of large uncollateralized loans is financially viable for the lender.
Armenia 2024-11-06 10:05:12 2027-11-06 Social Science and Humanities Non-Clinical Trial Non-degree Award
Simon  Kasasa
ID: UNCST-2021-R012861
Impact and Process evaluation of the Global Alliance for Improved Nutrition (GAIN) Urban Vegetable Project in Uganda
REFNo: HS5075ES

1. Assess the effectiveness of GAIN’s Urban Vegetable Project in Uganda for increasing the quantity of vegetables consumed and improving the diet quality of BoP consumers, specifically women and children. 2. Conduct a process evaluation of GAIN’s program that provides data for a PIP analysis to support the findings of the impact evaluation.,This aims at conducting an impact and process evaluation of GAIN’s Urban Vegetable Project in Uganda in order to generate evidence that will contributes to the body of knowledge that will be used to guide future dietary interventions in the country ,
Uganda 2024-11-06 10:01:53 2027-11-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hellen Opolot
ID: UNCST-2019-R001724
Assessing Knowledge and Perceptions of Gene Therapy Use Towards the Establishment of a National Regulatory Guidance Document in Uganda
REFNo: HS5136ES

1.2 Overall Objective
To explore the knowledge and perceptions of gene therapy use and application towards the establishment of a contextual regulatory guidance document for Uganda.
1.2.1 Specific Objectives
i. To determine the current state of gene therapy research in Uganda.
ii. To explore the knowledge and perceptions of researchers and regulators on gene therapy research and application in Uganda
iii. To examine the existing national, regional and international guidance documents governing gene therapy and identify areas that can be incorporated in the gene therapy guidance development for Uganda.
iv. To identify challenges and opportunities for advancing gene therapy in Uganda.

Uganda 2024-11-01 23:10:40 2027-11-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Hellen Opolot
ID: UNCST-2019-R001724
Assessing the Determinants of the Intention to Adhere to a Research Integrity Code and Open Science Practices in Four Selected Countries In Sub-Saharan Africa
REFNo: SS3376ES

5.1 General Objective
The broad objective of this study is to assess the determinants of the intention to adhere to a RI CoC and open science practices among research stakeholders across the four selected countries in Sub-Saharan Africa.
5.2 Specific Objectives
The specific objectives of the study will be:

1. To describe the participant background information, the six predictor domains, the moderating domain and the outcome domain.

2. To determine whether the six predictor domains, the moderating domain and the outcome domain vary by participant background.

3. To investigate the pair-wise relations between the participant background, the six predictor domains, the moderating domain and the outcome domain.


4. To determine the extent to which the pair-wise relations in Objective 3 vary by participant background characteristics and the moderating domain.

5. To analyze the perspectives of stakeholders on the facilitators and barriers to implementing Research Integrity Code of Conduct in Uganda.




Uganda 2024-11-01 23:09:26 2027-11-01 Social Science and Humanities Non-Clinical Trial Non-degree Award
ARINAITWE ENID
ID: UNCST-2024-R002911
SPILLOVER, BOUNDARY MANAGEMENT, SOCIAL NORMS AND EMPLOYEES’ WORK-LIFE BALANCE IN NATIONAL REFERRAL HOSPITALS IN KAMPALA – UGANDA
REFNo: SS3333ES

To analyse the combined effect of positive spillover, boundary management and social norms on employees’ work-life balance in national referral hospitals in Kampala.,To explore the effect of social norms on the work-life balance of employees in national referral hospitals in Kampala.,To evaluate the influence of boundary management practices on the work-life balance of employees in national referral hospitals in Kampala.,To assess the impact of spillover on the work-life balance of employees in national referral hospitals in Kampala.,The primary goal of this study is to investigate how spillover, boundary management, and social norms impact the work-life balance of employees at national referral hospitals in Kampala.,
Uganda 2024-10-31 17:33:43 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Mary Bekoreire Baremirwe
ID: UNCST-2024-R003317
Civil Society Organizations and Anti-Corruption Efforts in Uganda: Examining their Impact and Challenges
REFNo: SS3307ES

To examine the impact of CSOs in the fight against corruption in Uganda and their limitations in the pursuit of their goals,3. To recommend practical strategies can be adopted to enhance a conducive environment for CSOs operation in the fight against corruption in Uganda.,2. To examine the structural and process barriers that have affected the effectiveness of CSOs in the fight against corruption in Uganda.,
Uganda 2024-10-31 17:32:27 2027-10-31 Social Science and Humanities Non-Clinical Trial Non-degree Award
RICHARD ANGUALIA LAUS
ID: UNCST-2024-R002829
Organisational Politics and quality of road infrastructure Services in Kampala Capital City Authority in Uganda
REFNo: SS3375ES

3. Examine the influence of ethical management practices on sustainability of road infrastructure services in KCCA,2. Assess the contribution of institutional structures to resilience of roads infrastructure services delivery in KCCA,1. Analyze the influence of power dynamics on safety of road infrastructure service delivery in KCCA.,The main objective of the study is to examine the contribution of organizational politics to quality of roads infrastructure services deliverer in Kampala Capital City Authority (KCCA),
Uganda 2024-10-31 17:29:41 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
John Bosco Ddamulira Mayanja
ID: UNCST-2022-R010819
Evaluation of the Integrated Community-Based HIV Service Delivery Model (ICSDM) in Uganda: Analysis of Outcomes, experiences, and Cost.
REFNo: HS4916ES

The overall objective of the evaluation is to assess the implementation of ICSDM in Uganda to generate evidence on how well the model is working, and whether the desired health outcomes are being achieved.
1) To assess to what extent the implementation process for the delivery of ICSDM services is in accordance with the implementation guidelines and plan.
2) To assess the outputs as well as the primary (viral load re-suppression) and secondary outcomes of the implementation of ICSDM.
3) To explore the experiences, facilitators, challenges and lessons learned implementing ICSDM—the implementer and beneficiary perspective.
4) To determine annual and unit costs of the ICSDM program

Uganda 2024-10-31 17:27:42 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Olivia Nakisita
ID: UNCST-2020-R014431
A community Intervention to Improve the Sexual and Reproductive Health of Adolescents and Young People in Wakiso District, Uganda
REFNo: HS4875ES

To asses the impact of the multi strategy intervention to improve the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,To implement a multi component intervention to improve the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,To assess the baseline situation of the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,To improve the sexual and reproductive health of adolescents and young people in Wakiso District, Uganda,
Uganda 2024-10-31 17:24:11 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Buregyeya
ID: UNCST-2020-R014116
Secondary distribution of HIV self-testing by Female Sex Workers, pre-exposure prophylaxis (PrEP) starter packs and brief counseling to promote PrEP initiation and persistence among high-risk men in Uganda
REFNo: HS4891ES

Determine acceptability, feasibility, and safety of the intervention, and preliminary estimates of the potential for the intervention, compared to the control, to promote PrEP initiation, adherence, and persistence among male clients,Conduct an initial (stage 1a) small pilot of the intervention and refine it in preparation for the stage 1b pilot trial,Create the proposed Kayungirizi intervention to promote PrEP initiation and persistence among male clients of FSW through qualitative research informing adaptation and integration of components of local models and aspects of evidence-based interventions,Our overall hypothesis is that secondary distribution of HIVST by FSW to their male clients as an entry point to generate demand for PrEP, followed by an FSW-led intervention to address ongoing structural, interpersonal, and individual-level barriers (convenience, confidentiality/stigma, flexibility) will promote PrEP initiation, adherence, and persistence among male clients. ,
Uganda 2024-10-31 17:21:44 2027-10-31 Medical and Health Sciences Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
AIR QUALITY AND FOOD PREPARATION IN LOW -INCOME COMMUNITY IN KAMPALA-UGANDA: ACOMPARATIVE STUDY OF TWO COOKING STOVES
REFNo: HS5085ES

The overall purpose of the study is to determine if the novel samuchit steam cookers use a different amount of fuel, generate lower levels of PM, and have reduced cooking times compared to the traditional sigiri charcoal stoves,
Uganda 2024-10-31 17:14:55 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
NAOME KAKUNDWA
ID: UNCST-2023-R007057
Corporate governance practices and financial performance of Saving and Credit Cooperatives (SACCOs) in Bushenyi Uganda
REFNo: SS3030ES

To examine the influence of member participation on the financial performance of SACCOs in Western Uganda,To establish the effect of Transparency & accountability on the financial performance of SACCOs in Western Uganda,To examine the influence of Audit committee practices on the financial performance of SACCOs in Western Uganda,To assess the effect of Board practices on the financial performance of SACCOs in Western Uganda,
Uganda 2024-10-31 16:50:17 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Brown Alice
ID: UNCST-2023-R006208
A Longitudinal Study of the Development of Multimodal Combinational Communication in Chimpanzees
REFNo: NS834ES

To understand and explore the ontogeny of combinational communication in chimpanzees (Pan Troglodytes) to provide insights to the evolution of human language. To understand how non-adult chimpanzees develop the multimodal combinatorial communication that has been seen in adult chimpanzees. To assess the role social learning may play in the acquisition of multimodal combinatorial communication, by (i) comparing non-adult repertoires to those of their mother (social learning model) and father (not a social learning model) and (ii) by examining cross -community differences in adult repertoires.
UK 2024-10-31 16:48:44 2027-10-31 Natural Sciences Non-Clinical Trial Degree Award
ROVINE NALUYIMBAZI
ID: UNCST-2024-R005302
Expanding laparoscopic simulation in Uganda
REFNo: HS4783ES

Aim 3: Create, conduct, and review a hybrid laparoscopic surgery training course for practicing Ugandan surgeons.,Aim 2: Create a low-cost, high-fidelity laparoscopy training model. We will utilize the Duke-Muk educational partnership that forms the foundation for the Shipping Container MakerSpaces to develop and build a laparoscopic training model, demonstrating the effectiveness of the previously developed infrastructure for biomedical engineering.,Aim 1: Assess level of baseline laparoscopic training and experience for Ugandan surgeons. We will survey the members of the Ugandan Surgical Society regarding their needs, expectations, and willingness to participate in a laparoscopic training course,We will assess the needs of local surgeons and trainees about their needs and experiences in laparoscopy to develop a low-cost box-trainer that is manufactured locally. This box will enable LMIC surgeons to develop the fundamental skills necessary to perform laparoscopy and improve surgical patient outcomes. The developed box trainer will form the foundation of a hybrid laparoscopy training course to be facilitated by local surgical and medical educators.,
Uganda 2024-10-31 16:41:56 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ombeva  Malande Oliver
ID: UNCST-2024-R004335
LIVED EXPERIENCES OF SURVIVORS OF VACCINE PREVENTABLE DISEASES IN UGANDA
REFNo: HS4189ES

3. To analyze the views of the caregivers to and survivors of vaccine preventable diseases in Uganda concerning the role of vaccines and vaccination in disease prevention?,2. To determine and document the lived experiences of caregivers to people suffered from or died from vaccine preventable diseases in Uganda?,1. To determine and document the lived experiences of survivors of vaccine preventable diseases in Uganda?,
Kenya 2024-10-31 16:35:06 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
Validation of the liquid biopsy to diagnose endemic Burkitt lymphoma in children in Uganda.
REFNo: HS4525ES

To compare the performance of the liquid biopsy test with conventional pathology in diagnosing endemic Burkitt lymphoma in Uganda. ,To evaluate the turnaround times for liquid biopsy and conventional pathology for diagnosing EBVL in real life settings in Uganda,To compare the sensitivity and specificity of liquid biopsies versus locally enhanced available pathology in Uganda.,To validate the liquid biopsy to diagnose endemic Burkitt lymphoma in children and young adults in Uganda.,
Uganda 2024-10-31 16:17:43 2027-10-31 Medical and Health Sciences Non-Clinical Trial Non-degree Award
PIUS MATOVU DDUMBA
ID: UNCST-2024-R004025
Family Environment and Depressive Symptom among older adults in Central Uganda: The Mediating Role of Patient Factors
REFNo: SS2854ES

6. To test the causal model indicating whether patient factors have a mediating effect on family environment and depressive symptoms among older adults in Central Uganda using SEM modeling.,5. To assess the influence of patient factors on depressive symptoms among older adults in Central Uganda.,4. To examine the relationship between patient factors and family environment among older adults in Central Uganda.,3. To examine the influence of system maintenance on depressive symptoms among older adults in Central Uganda.,2. To assess the effect of personal growth on depressive symptoms among older adults in Central Uganda.,1. To analyze the influence of interpersonal relations on depressive symptoms among older adults in Central Uganda.,The purpose of this study is to analyze the effect of family environment on depressive symptoms among older adults in Central Uganda.,
Uganda 2024-10-31 16:12:27 2027-10-31 Social Science and Humanities Non-Clinical Trial Degree Award
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