Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Conrad Muzoora Kihembe
ID: UNCST-2019-R001432
Intensified tuberculosis treatment to reduce the mortality of HIV-infected and uninfected patients with tuberculosis meningitis: a Phase III Randomized Controlled Trial. ANRS 12398 INTENSE-TBM
REFNo: HS804ES

The Primary objective is to assess the efficacy of two interventions to reduce mortality from TBM in adolescent and adults with or without HIV co-infection in sub-Saharan Africa:
• Intensified TBM treatment, compared to WHO standard TBM treatment
• Aspirin compared to not receiving Aspirin (placebo).

Uganda 2020-12-10 2023-12-10 Medical and Health Sciences Non-degree Award
Irene Among Among
ID:
A Gender, youth and social inclusion analysis of Pathfinder’s family planning program in Kyegegwa, Kyenjojo, Kibaale, Kyankwanzi, Buliisa, Ntoroko, Bundibugyo, Kiryandongo, Gomba, Rakai and Butambala districts
REFNo: SS646ES

1. To identify the vulnerable/marginalized/underserved and hard-to-reach population segments in the FPA catchment districts.
2. To define the systemic barriers faced by such population segments in accessing SRH/FP information and services, structured around the six domains of USAID’s gender analysis framework - access, beliefs, practices, time/space, rights, and power.
3. To make recommendations on innovative approaches that the FPA could take to address barriers and improve access to quality reproductive health services and adoption of positive reproductive health behaviors.
4. With precision to gender and youth, to provide further recommendations as appropriate, on innovative strategies based on local needs, to mainstream gender and youth programming into national/district health planning by detailing specific gender-focused and youth-focused activities for each result area of the project.

Uganda 2020-12-10 2023-12-10 Social Science and Humanities Non-degree Award
Lawrence Mugisha
ID:
MONITORING OF DISEASES AND ANTIMICROBIAL USE IN POULTRY FARMING BY USE OF INFORMATION AND COMMUNICATION TECHNOLOGY TO CONTROL ANTIMICROBIAL RESISTANCE (AMR) IN WAKISO DISTRICT; UGANDA
REFNo: A100ES

The overall objective of the project is to provide an ICT framework for improved monitoring and control of AMU and AMR in poultry farmers in Wakiso District, Uganda.

Specific objectives

• To perform a stakeholder analysis in order to establish all players in poultry farming systems in Wakiso District
• To examine practices, attitudes, knowledge and behavior of poultry farmers in Wakiso District
• To collect data on poultry diseases, access and use of antibiotics in Wakiso district
• To develop and deploy an ICT platform to monitor AMU, AMR and disease prevalence’s in poultry in Wakiso District
• To examine the role of ICT in the implementation and management of Poultry projects in Wakiso District

Uganda 2020-12-09 2023-12-09 Agricultural Sciences Non-degree Award
Haruna Muwonge
ID: UNCST-2019-R000128
SUPPLEMENTS, HERBS AND DOPING PRODUCTS USAGE AMONG UGANDAN ATHLETES AND COACHES
REFNo: SS507ES

1. To evaluate supplement and herbal product usage amongst athletes from all major sporting codes in Uganda
2. To evaluate the usage of doping substances or methods amongst Ugandan athletes from all major sporting codes.
3. To determine the existing framework for intervening in herbal products usage among athletes and support personnel in Uganda
4. To examine the existence of anti-drug abuse interventions targeting the misuse of herbal products among Ugandan athletes and support personnel.
5. To determine the level of susceptibility to doping agent usage among Ugandan athletes and suggest recommendations for an intervention.

Uganda 2020-12-08 2023-12-08 Social Science and Humanities Non-degree Award
Dominic Kathiya Lokeris
ID:
Characterization of Cross Border Livestock Mobility and Utilization of Rangeland Resources: A Case Study of Karamoja Cluster
REFNo: A91ES

Broad Objective:
To characterize cross-border livestock mobility and assess the utilization of rangeland pastures and water in the Karamoja cluster.

Specific objectives:
1.To describe cross-border livestock mobility in Karamoja cluster.
2.To assess the knowledge, practices and perceptions of pastoral communities on utilization of rangeland pastures and water in Karamoja Cluster.
3.To establish the decision makers of livestock mobility and utilization of the rangeland pastures and water in Karamoja Cluster.

Uganda 2020-12-08 2023-12-08 Agricultural Sciences Degree Award
Wilfred Eneku
ID:
Molecular and Sero-epidemiology of zoonotic rickettsia in five districts of Uganda
REFNo: HS897ES

1. To determine seroprevalence and risk factors to rickettsioses in the five districts from archived serum samples and the accompanying secondary data
2. To characterize rickettsia in Vectors in five districts of Uganda
3. To assess the relative densities of ticks and fleas on animals and environment in the five districts of Uganda

Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Degree Award
Kristie McComb
ID:
Evaluation of the Patient Navigation Program at Uganda Cancer Institute
REFNo: HS1014ES

The goal of this study is to document the experiences and lessons learned (through a baseline and endline process evaluation), and the ways in which this program improved outcomes for cancer patients (through an outcome evaluation). These evaluations will document best practices for other countries considering similar projects, provide programmatic evidence on the usability and effectiveness of the program development methodology, and guide development of a resource toolkit for other health institutions like UCI seeking to start a patient navigation program.

The evaluation questions are:

Process Evaluation (2020 and 2021)
1. Coordination and Referral: Has the patient navigation program increased coordination/ referral of patients within Uganda Cancer Institute (UCI) and with other support services (e.g. Civil Society Organizations (CSO), psychosocial services and other necessary services)?
2. Fidelity and Adaptation: To what extent is the patient navigation program implemented as intended and what changes to the program have been made over time?
3. Improving Understanding of Care: To what extent does the patient navigation program reduce barriers to understanding cancer diagnosis and accessing treatment services and how does patient navigation increase adherence to patient treatment plans?
4. Training and Technical Assistance: How effective is the training and technical assistance provided by American Cancer Society (ACS) in supporting new patient navigation program design, preparation and implementation?
5. Sustainability: How prepared is the program to transition to UCI ownership?

Outcome Evaluation (2023)
1. To what extent, if at all, are the program activities focused on addressing the needs of the target population?
2. To what extent do decision makers and other stakeholders view patient navigation as the right intervention to address challenges to patient access to cancer treatment?
3. How effective is the patient navigation program at improving hospital processes and service delivery?
4. How effective is the patient navigation program at improving desired outcomes at the individual patient and caregiver level?
5. How effective is the training and technical assistance provided by ACS in supporting new patient navigation program design, preparation and implementation?
6. To what extent is the patient navigator program likely to continue after ACS support ends?

USA 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
Clinical characterization and preparedness for COVID-19 disease (CCP)
REFNo: HS1041ES

• Describe the clinical features of COVID-19 and monitor the progress of all hospitalized patients including what is working and what is not.
• Describe, where appropriate, the response to treatment, including supportive care and novel therapeutics.
• Observe, where appropriate and feasible, pathogen replication, excretion and evolution, within the host, and identify determinants of severity and transmission using high throughput sequencing of pathogen genomes obtained from respiratory tract, blood, urine, stool and other samples.
• Characterise, where appropriate and feasible, the host responses to infection and therapy over time, including innate and acquired immune responses, levels of immune signaling molecules in relevant body compartments and gene expression profiles in peripheral blood.
• Understand transmissibility and the probabilities of different clinical outcomes following exposure and infection.
• To describe COVID 19 related haematological and biochemical changes

Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
Charity Okaba
ID:
Understanding Community-oriented Prosocial Behaviors in Uganda
REFNo: SS641ES

The proposed study aims to investigate and contextually define relevant categories of prosocial behaviors and the demographics and individual characteristics associated with such prosocial behaviors, in Uganda. There are three major reasons that motivate why this research is much needed:
Firstly, this research will aim to define prosocial behaviors in the context of Uganda and demonstrate methods to capture and categorize them, both of which have currently been defined by Western research. We seek to understand the variations in the way people perceive and engage in prosocial behaviors in an under-researched context and contribute our results to the existing body of literature.
Second, this research will further explore how individual characteristics (both demographics and psychographic) are associated with different contextualized categories of prosocial behaviors. Existing research has largely explored demographic links to some extent but has overlooked the link between other individual differences to the level of engagement with prosocial behaviors.
Finally, the results from the proposed research will have far-reaching impacts for social and community development, including but not limited to community-based groups, as well as researchers, practitioners, and policymakers. Our research can be easily used to guide the design and framing of communication to encourage engagement in prosocial behavior that promote community development and improve welfare.
Uganda 2020-12-08 2023-12-08 Social Science and Humanities Non-degree Award
Daniel  Kaye Kabonge
ID:
COUNTRY-WIDE ESTIMATES OF THE INCIDENCE OF ABORTION AND ABORTION-RELATED MORBIDITY IN UGANDA
REFNo: HS1074ES

To systematically generate reliable nationwide evidence on the scale and distribution of the burden of unsafe abortion in Uganda and its effects, so as to engage policy and decision makers through further discussion of the subject in a amore contextualized manner. Specifically, to establish the incidence and distribution of unsafe abortion in Uganda, to estimate the effects of the burden of unsafe abortion in Uganda (in terms of magnitude of abortion complications) and to provide recommendations for decision makers on future programming for abortion care in Uganda
Uganda 2020-12-08 2023-12-08 Medical and Health Sciences Non-degree Award
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