JOSEPH Ngonzi
ID:
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Quality Improvement Initiative in the Department of Obstetrics and Gynaecology
REFNo: HS967ES
1) To measure current health outcomes in the unit
2) To describe and analyze current process, behaviors, resources and availability
3) To develop and implement changes in current practices to improve outcomes while maximizing resources.
4) To monitor and evaluate health outcomes in the department of OB/GYN
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Uganda |
2021-03-12 |
2024-03-12 |
Medical and Health Sciences |
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Non-degree Award |
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Margaret Joanita Mutumba Nakalembe
ID:
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Multi-level Analysis on Implementation of Low-Cost IVF in Sub-Saharan Africa:
A Case Study of Uganda.
REFNo: HS1214ES
The objective of this study is to explore how LCIVF has been implemented in the public health system of Uganda. The more specific questions include; 1) How has LCIVF been operationalized at the micro-level within the clinical practice? 2) How has the public hospital at the meso-level organized itself to facilitate the implementation and provision of LCIVF? 3) How have macro-level factors influenced the implementation of LCIVF within the public health system? 4) How effective has the implementation of LCIVF been in addressing accessibility and affordability of infertility services in Uganda?
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Uganda |
2021-03-12 |
2024-03-12 |
Medical and Health Sciences |
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Degree Award |
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Nixon Niyonzima
ID: UNCST-2020-R014577
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MUTATIONAL PROFILE OF TRIPLE NEGATIVE BREAST CANCER IN WOMEN SEEKING CARE AT THE UGANDA CANCER INSTITUTE
REFNo: HS1264ES
1. To describe the mutational profile of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
2. To describe the relationship between the mutational load and the primary tumor size of triple negative breast cancer in women seeking care at the Uganda Cancer Institute
3. To describe the differences in mutational profile by histological type in patients with triple negative breast cancer in women seeking care at the Uganda Cancer Institute
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Uganda |
2021-03-12 |
2024-03-12 |
Medical and Health Sciences |
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Degree Award |
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Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
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An Evaluation of the Pediatric Care Process in Uganda for Improvement of Quality of Care
REFNo: HS1227ES
The primary objective of this study is to evaluate the typical pediatric care process at a representative sample of hospitals in Uganda
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Uganda |
2021-03-11 |
2024-03-11 |
Medical and Health Sciences |
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Non-degree Award |
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Peter Olupot-Olupot
ID:
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Severe MAlaria A Research and Trials consortium: A protocol for a prospective case control observational study
REFNo: HS1231ES
To characterise the contemporary epidemiology (including features at presentation and the diagnostic and treatment pathway) of severe malaria presenting to hospital for admission in children in Africa, through conducting a prospective multicentre observational study across 7 sites in 6 countries, enrolling two cohorts of hospitalised children (i.e. stratified) with severe and non-severe malaria.
For this study, severe malaria will be defined as children with a positive POC pHRPT2 test (Paracheck) meeting WHO criteria or Teule criteri. For severe malaria, we will characterise the proportions presenting with different severe complications, or combination of any of or all of these, and compare these proportions across sites.
Secondary Objectives
i. To compare baseline characteristics of admitted children with severe and non-severe malaria.
ii. To document time from presentation to the hospital ‘gateway’ (e.g. outpatients or emergency/triage centre) to ward admission and time to first dose of parenteral artesunate to assess whether delays in initiating definitive antimalarial treatment could contribute to malaria severity.
iii. To estimate the incidence of significant post-discharge events to day-180 including readmission (all-cause and for malaria (i.e. relapse)) and all-cause mortality in severe and non-severe malaria.
iv. To develop (year 1) and evaluate (years 2 and 3) a point-of-care quantitative plasma Plasmodium falciparum histidine-rich protein2 (pfHRP2) test for estimating total body parasite burden, which could be used to swiftly identify those at greatest risk of poor outcomes.
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Uganda |
2021-03-11 |
2024-03-11 |
Medical and Health Sciences |
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Non-degree Award |
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Tom Lutalo
ID:
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Measuring adult health and mortality in Low- and Middle-Income Countries
REFNo: HS640ES
1. To evaluate the accuracy of survey data on adolescent and adult mortality collected retrospectively through siblings’ survival histories (SSH), compared to the reference mortality data collected prospectively.
2. To test whether the siblings of respondents can be reached and interviewed via mobile phone, in order to collect data on the risk factor of adult mortality
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Uganda |
2021-03-10 |
2024-03-10 |
Medical and Health Sciences |
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Non-degree Award |
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Levicatus Mugenyi
ID: UNCST-2020-R014759
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Understanding Factors Associated with IPT Completion among Recipients of Care on ART/IPT Aligned Multi-month Refills across the Differentiated Service Delivery Models
REFNo: HS1228ES
The primary objective is to understand factors associated with completion of IPT among clients in MoH’s integrated IPT/ART models.
Specific objectives:
1.To compare IPT completion rates amongst clients across the five DSD models: Facility-Based Individual Management (FBIM), Facility-Based Group (FBG), Fast Track Drug Refill (FTDR), Community Client Led ART Delivery (CDDP), and Community Drug Distribution Points (CCLAD).
2.To understand individual and facility level factors associated with IPT completion across the different DSD models
3.To compare IPT uptake across the different DSD models
4.To compare the frequency of adverse events (AEs) reported by clients on IPT across the different DSD models
5.To document patient and service provider KAP towards the IPT/ART integrated model
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Uganda |
2021-03-10 |
2024-03-10 |
Medical and Health Sciences |
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Non-degree Award |
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Pontiano Kaleebu
ID: UNCST-2021-R013577
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A Phase 1 Trial of ChAdOx1- and MVA-vectored Conserved Mosaic HIV-1 Vaccines in Healthy, Adult HIV-1-negative Volunteers in Eastern and Southern Africa
REFNo: HS844ES
Safety
ï‚· To evaluate the safety and tolerability of a prime boost vaccine regimen utilizing non-replicating simian adenovirus (ChAdOx1) followed by non-replicating poxvirus modified vaccinia virus Ankara (MVA) in adults in Eastern and Southern Africa
Immunogenicity
ï‚· To evaluate the specific T-cell immune responses induced by the ChAdOx1.tHIVconsv1 followed by MVA.tHIVconsv3&4 vaccines in vaccine recipients.
SECONDARY
ï‚· To assess tHIVconsvX-specific T-cell responses of for their frequency, breadth and duration in vaccine recipients.
ï‚· To assess functional T-cell responses in vaccine recipients that inhibit replication in vitro of viruses of major HIV-1 clades A, B, C and D.
EXPLORATORY
ï‚· To assess induction of plurifunctional tHIVconsvX-specific memory T cells in the vaccine recipients.
ï‚· Characterization of the gut microbiome composition and richness.
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Uganda |
2021-03-05 |
2024-03-05 |
Medical and Health Sciences |
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Non-degree Award |
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Esther Buregyeya
ID: UNCST-2020-R014116
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USING SHORT MESSAGE SERVICE REMINDERS AND MOBILE MONEY INCENTIVES TO ENHANCE LINKAGE TO CARE OF PRESUMPTIVE TUBERCULOSIS PATIENTS IN UGANDA: A RANDOMISED CONTROLLED TRIAL
REFNo: HS993ES
To evaluate the TB diagnostic process and linkage to care by doing cohort analysis.
2. Develop and adapt an SMS reminders and MM incentives to improve linkage to care among TB patients.
3. Conduct a randomized controlled trial of SMS reminders and MM incentives sent to presumptive and confirmed TB patients to improve linkage to care and treatment.
4. To build sustainable capacity in TB research clinical trials in Uganda.
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Uganda |
2021-03-05 |
2024-03-05 |
Medical and Health Sciences |
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Non-degree Award |
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Jude Onyango Tadeo
ID:
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FAMILY SUPPORT, DIABETES SELF-MANAGEMENT, AND GLYCEMIC CONTROL AMONG PATIENTS ATTENDING DIABETIC CLINICS OF REGIONAL REFERRAL HOSPITALS IN EASTERN UGANDA (FS-DSM-GC STUDY)
REFNo: HS1040ES
Research Study objectives:
General objective:
To examine the association between perceived family support, diabetes self-management behavior and glycemic control among patients attending Regional Referral hospitals in the eastern region of Uganda.
Specific objectives:
1. To determine the association between perceived family support and diabetes self-management behavior among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.
2. To determine association between perceived family support and glycemic control among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.
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Uganda |
2021-03-05 |
2024-03-05 |
Medical and Health Sciences |
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Non-degree Award |
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