Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Moses Chemurot
ID:
Exploring stingless bee products for nutritional and medicinal values in Uganda (Bee-Nutri-Medicine project)
REFNo: HS1131ES

Investigate the potency of stingless bee honey and propolis as medicines for wounds and skin infections,Explore antimicrobial properties of honey and propolis collected from stingless bee colonies in Uganda,Determine the nutritional profiles of pollen and honey harvested from two stingless bee species in Uganda. This will guide in the promotion of bee pollen consumption as alternative sources of protein especially for poor rural households.,Explore stingless bee products for nutritional and medicinal purpose in Uganda,
Uganda 2020-12-24 2023-12-24 Medical and Health Sciences Non-degree Award
Margaret Kabahenda
ID:
Strengthening the capacity of teachers to integrate nutrition education in school curricula to improve children’s dietary practices and physical actlivity so as to combat malnutrition [TEACH-Nutrition Project]
REFNo: A93ES

Determine the effectiveness of the proposed intervention model in improving: (a) teachers nutrition knowledge and ability to monitor pupils’ nutritional status; (b) pupils’ dietary practices and physical activity patterns; (c) parents’ knowledge of their children’s nutritional needs and their capacity to provide nutritious foods to their children; and (d) schools management’s commitment to address food and nutrition issues,Determine the barriers and supports for integrating nutrition education in school curricula,Develop an effective nutrition education intervention model that can easily be integrated in lower primary school curricula,Characterize the available nutrition education training programs, materials, and the types and innovation habits of actors engaged in school nutrition education,
Uganda 2020-12-21 2023-12-21 Agricultural Sciences Non-degree Award
Chrispo Maali
ID:
Remuneration and Performance of Teachers in Government Aided Secondary Schools in Kasese District, Western Uganda
REFNo: SS512ES

1.To explore the forms of remuneration in government aided secondary schools in Kasese District.
2.To examine the level of teachers performance in government aided secondary schools in Kasese District
3.To examine the relationship between remuneration and teacher performance in government aided secondary schools in Kasese District.

Uganda 2020-12-21 2023-12-21 Social Science and Humanities Degree Award
Clement Okello Dove
ID: UNCST-2020-R014649
TREATMENT RESPONSE AND TREATMENT RELATED MORTALITY IN PATIENTS WITH ACUTE MYELOID LEUKAEMIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS946ES

1. To describe the clinical characteristics of patients with acute myeloid leukaemia at the Uganda Cancer Institute. 2. To determine the induction treatment response rate in patients with acute myeloid leukaemia at the Uganda Cancer Institute. 3. To determine the rate of induction treatment related mortality in patients with acute myeloid leukaemia at the Uganda Cancer Institute. 4. To determine the predictors of induction related mortality in patients with acute myeloid leukaemia at the Uganda Cancer Institute.
Uganda 2020-12-21 2023-12-21 Medical and Health Sciences Non-degree Award
Lydia Nakiyingi
ID:
Development of large-scale panel of TB patient urine and serum samples to serve as standards for detection of TB LAM in HIV-positive and negative presumptive TB patients
REFNo: HS1006ES

Primary:
•Estimate the sensitivity of the investigational urine LAM test for detection of culture-confirmed Mycobacterium tuberculosis infection among individuals with clinical signs and/or symptoms of TB.
•Examine the effect of HIV infection and CD4 cell level on sensitivity of these assays
•Compare the sensitivity of the existing FujiLAM and AlereLAM assays with new investigational LAM tests

Secondary:
•Use large-scale samples to compare the immunological properties of urinary LAM in different patients, and to perform structural analyses of the urinary LAM antigens
• Develop and distribute aliquots of characterized large-scale urine samples for standardization and optimization of a point-of-care format of the investigational urine LAM assay.


Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Janet Nakigudde
ID: UNCST-2019-R000444
Effectiveness and Implementation of an Early Childhood School-Based Mental Health Intervention in Low-Resourced Communities in Hoima and Kampala districts-Uganda
REFNo: HS1057ES

1. To evaluate the short and long term effectiveness of Professional Development (PD alone) and Professional Development plus wellness Training (PDT)
2. To examine the effectiveness mechanisms and theory of change underlying the EBIs
3. To examine implementation contextual factors and mechanisms that contribute to teachers' uptake and sustainment of EBI strategies within PD and PDT schools.
Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Carolyne Onyango
ID:
Re-Calibration of Quantitative and Contextual Factors to Predict Child Cognitive Deficits in HIV-Exposed Children in the PROMISE/PROMOTE Study Cohorts (CD PROMOTE Study) Version 2.0, dated 08 March 2020
REFNo: HS795ES

1. To identify clinical, maternal, home-environment factors that are associated with the risk of CD among HIV exposed but uninfected children.
2. To develop a CD risk prediction tool for HIV exposed uninfected children informed by identified risk factors observed in Aim 1 and existing literature

Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Bruce Twinamasiko
ID:
FEASIBILITY OF A COMMUNITY HEALTH WORKER-LED INTERVENTION TO CONTROL HIGH BLOOD PRESSURE IN SOUTHWESTERN UGANDA: A PILOT PRAGMATIC CLUSTER RANDOMIZED TRIAL (CHIP TRIAL)
REFNo: HS881ES

1.To test whether a multifaceted intervention program will lead to blood pressure control among patients with uncontrolled blood pressure over a 12-month period compared to usual care.
2.To evaluate whether a multifaceted intervention program will improve hypertension control among hypertensive patients over a 12-month period, compared to usual care.

Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Grace Ndeezi
ID: UNCST-2019-R001802
Effect of Vitamin D supplementation on Sickle cell disease hospitalisation and related complications among Children in Mulago Hospital: A randomised clinical trial
REFNo: HS985ES

Objectives
The overarching goal for this study is to evaluate whether vitamin D supplementation can decrease the need for hospitalisations in Ugandan children with SCD
Primary objectives:
1. To determine the frequency of hospitalisation among children with SCD supplemented with vitamin D versus placebo.
2. To determine the effect of vitamin supplementation on serum levels of 25 Hydroxyvitamin D levels in children with SCD

Secondary objectives:
To determine the:
1. Incidence of vaso-occlusive crises (VOC)
2. Incidence of acute severe respiratory illnesses
3. Severe adverse events
4. Requirements for blood transfusion among children supplemented with vitamin D versus Placebo in children with sickle cell anaemia

Uganda 2020-12-18 2023-12-18 Medical and Health Sciences Non-degree Award
Tumuhairwe Juliet
ID:
The Challenge Initiatives Approach to City engagement – Coaching case study
REFNo: SS645ES

This study is meant to explore the successes, challenges and innovations of The Challenge Initiative’s (TCI) coaching model


Specific objectives
1. Document the intensity and focus of TCI coaching to-date, including which high-impact approaches governments most commonly request coaching for, how often, and what their impact has been.
2. Explore how local governments and service providers perceive the TCI coaching model, including, whether they believe it has been beneficial, and if so, how.
3. Understand if TCI’s coaching has led to system strengthening and improvements in the healthcare system both related to family planning and AYSRH service delivery, but also beyond. Additionally, document which system strengthening elements of coaching are most notable to TCI beneficiaries.
4. Document the ways in which TCI’s coaching has worked well and, perhaps, not worked as planned. Use this information to develop recommendations for how TCI can strengthen its coaching model.
5. Understand how the TCI coaching model can be sustained by TCI supported geographies even after a city ‘graduates’ from TCI (i.e., achieves program success and certain milestones, indicating the city no longer needs TCI’s support)

Uganda 2020-12-18 2023-12-18 Social Science and Humanities Non-degree Award
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