Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Teddy Nakubulwa
ID:
Sexual and Reproductive Health and Economic Empowerment –Supporting Out-of-school Adolescent girls’ Rights and Skills (SHE SOARS) Program
REFNo: SS1225ES

4) Identify programmatic priorities and approaches through key informant interviews with stakeholders such as government staff, community leaders, health care providers and staff from other sexual reproductive health rights projects.,3) Contribute to the evidence base surrounding Gender Equality and Sexual Reproductive Health outcomes for adolescent s through documenting evidences of how the project is rendering effective, relevant, efficient and sustainable solutions to target project participants. ,2) Examine the current knowledge, attitudes and practices related to sexual reproductive health and gender equality among adolescents, particularly out-of-school adolescents, to inform project implementation ,1) Establish baseline, mid term and endline values for all indicators for the SHE SOARS project.,
 Uganda 2022-04-02 2025-04-02 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ninsheka  Leonard
ID:
Analysis of the Effects of the Forms and Drivers of Urban Agriculture on the socio-Economic Status of Farmers in Kampala and Mbarara Cities, Uganda
REFNo: A172ES

1) Examine the forms of urban agriculture on the socio-economic status of the urban farmers
in Kampala and Mbarara Cities.
2) Examine the Drivers of urban agriculture on the socio-economic status of the urban farmers
in Kampala and Mbarara Cities.
3) Establish appropriate policy directions of urban agriculture on the socio-economic status
of urban farmers in Kampala and Mbarara Cities.
4) To establish the influence of socio-demographic characteristics on the socio-economic
status of urban farmers in Kampala and Mbarara Cities

 Uganda 2022-04-01 2025-04-01 Agricultural Sciences Non-Clinical Trial Degree Award
Alinda  Fred
ID:
ADVANCING AGRICULTURAL INSURANCE IN UGANDA’S CLIMATE CHANGE ADAPTATION: DETERMINANTS AND STRATEGIES FOR INSURANCE UPTAKE
REFNo: A181ES

1. To assess the agricultural insurance positioned in the climate change adaptation framework for Uganda and what are the critical gaps
2. To assess the demand and supply side constraints to adoption of agricultural insurance in Uganda borrowing insights from empirical literature in other countries
3. To identify the existing strategies to promoting agricultural insurance as an overarching climate change adaptation strategy.
4. To identify strategies that Uganda can adapt to effectively promote agricultural insurance as a climate change adaptation strategy.

Uganda 2022-04-01 2025-04-01 Agricultural Sciences Non-Clinical Trial Degree Award
Alfred Jatho
ID: UNCST-2021-R011710
 Barriers to and Facilitators of Prostate Cancer Screening among Men in Uganda Prisons
REFNo: HS2128ES

The goal of this study is to examine the perceptions, attitudes and beliefs of men in Uganda Prisons regarding barriers to and facilitators of PCa screening. This will enable the research team to identify potential interventional strategies to promote PCa screening among men in Uganda prisons.,
 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joaniter Nankabirwa Immaculate
ID: UNCST-2021-R012896
 Optimizing the use of SARS-Cov-2 antigen rapid diagnostic tests (Ag-RDT) for timely detection and effective response to COVID-19 in key border communities in Uganda
REFNo: HS2050ES

To evaluate the feasibility of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.

To determine the yield of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in the border districts of Tororo and Busia districts

To assess the acceptability of active surveillance using the SARS-CoV-2 Ag-RDT in high-risk populations in border districts of Tororo and Busia.

 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Non-degree Award
helen harrison
ID:
A grounded theory epistemological exploration of wellbeing for women with lived experience of conflict-affected trauma, based in Uganda
REFNo: HS2148ES

- To use thematic-induced analysis to develop a theory relating to the epistemology of wellbeing that is grounded in the interview data,- To conduct semi-structured interviews with six – eight female participants from each of the communities.,- To explore the epistemology of wellbeing for women from three specific Uganda-based communities, each of whom has lived experience of conflict-affected trauma, and who are linked through trauma counselling,
 UK 2022-04-01 2025-04-01 Medical and Health Sciences Non-Clinical Trial Degree Award
Thereza Piloya Were
ID: UNCST-2019-R000491
 Diabetes in African Youth: Improving Glucose Time-In-Range (DAY Time) Randomized Clinical Trial.
REFNo: HS2129ES

Primary Study Objectives
1. To determine if patient ability to continuously observe plasma glucose levels for 6 months using a flash intermittently scanned CGM improves glucose TIR compared to baseline. The change in glucose TIR while wearing the unblinded CGM will be compared to change in TIR in patients performing 3x/day SMBG (wearing a blinded CGM for endpoint measurement).
2. To perform a cost analysis on flash glucose monitoring compared to 3x/day SMBG, to determine whether this technology is cost effective in the setting of a low-resource nation.
Secondary Objectives: To assess the change-from-baseline impact of unblinded CGM on:
1. Percent time-in-range at 12 months
2. Percent time with glucose 180-250, >250, <70, and <54 mg/dl at 6 and 12 months
3. HbA1c at 6 and 12 months
4. Patient satisfaction and quality of life at 6 and 12 months
5. Glucose variability (coefficient of variation, CV) at 6 and 12 months

 Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
 Performance evaluation of the CheckNOW™ HIV Self-Test study
REFNo: HS2170ES

1. To evaluate the performance (Sensitivity and specificity) of the CheckNOW™ HIV SELF TEST when compared to the Genscreen ULTRA HIV1/2 Ag/Ab EIA followed by the Murex diasorin HIV1/2 Ag/Ab combination (reference testing) in the laboratory and the national testing algorithm.

2. To describe the clinical performance (sensitivity and specificity) of the CheckNOW™ HIV SELF TEST, as obtained by the professional users, when compared to the reference testing and the national testing algorithm.

3. To describe the clinical performance (sensitivity and specificity) of the CheckNOW™ HIV SELF TEST, as obtained by the lay users, when compared to the reference testing and the national testing algorithm.

4. To assess the accuracy of the lay user interpretation of the HIVST result. This will be compared with the interpretation by the RA.
5. To assess the usability of the CheckNOW™ HIV SELF TEST. The usability of the test will be evaluated by questionnaires completed by the study staff observers and by the lay users.



Uganda 2022-04-01 2025-04-01 Medical and Health Sciences Clinical Trial Non-degree Award
Samson Okello
ID: UNCST-2019-R001580
 Epidemiology of cardiac dysfunction in sub-Saharan Africa: Heart Failure Registry of HIV-infected and HIV-uninfected persons in Uganda and Zambia
REFNo: HS788ES

1. To describe the clinical characteristics, treatment outcomes, and predictors of all-cause and CV mortality among HIV-infected and HIV-uninfected heart failure adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
2. To describe echocardiographic etiology of heart failure among HIV-infected and uninfected adults hospitalized at Mbarara Regional Referral Hospital (Mbarara, Uganda) and University of Zambia Hospital (Lusaka, Zambia).
3. To determine the differences in the serum markers of cardiac fibrosis, cardiac injury, oxidative stress, and hypercoagulability in HIV-infected and HIV-uninfected individuals hospitalized with heart failure at Mbarara Regional Referral Hospital and the University of Zambia Hospital.

 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-degree Award
Jennifer Ross
ID:
Modeling Approaches to Prioritize TB Prevention in Uganda
REFNo: HS1981ES

1. Estimate national, regional- or district-level patterns in prevalence, incidence, and mortality of TB and TBHIV using a geospatial model to identify geographic areas with higher versus lower infection burden.

2. Quantify the potential impact in disease burden and cost for PT scale-up in regionalized versus uniform implementation.

3. Engage stakeholders to inform model development and evaluate strategies to improve the acceptability and feasibility of modeled strategies for TB prevention.

 USA 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bernard Kikaire
ID:
Utility of using C - reactive protein (CRP) in identifying bacteremia in children below five years presenting with fever at the Kawempe National Referral hospital.
REFNo: HS2038ES

1. To assess the performance of CRP in identifying bacterial infection among children less than 5 five years presenting with fever Kawempe National Referral Hospital
2. To assess the performance of Neutrophilia in identifying bacterial infection among children less than 5 five years presenting with fever Kawempe National Referral Hospital
3. To compare the two diagnostic criteria in identifying children with bacteremia at Kawempe National Referral Hospital

 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
HARRIET NANKYA
ID:
Toward effective community engagement for genomics research in Uganda
REFNo: SS1172ES

1. To assess Genomics Researchers’ perspectives and practices on CE for genomics research in Uganda.
2. To explore Community Stakeholders’ experiences and perspectives on CE for genomics research in Uganda.
3. To assess research regulators’ perspectives on what constitutes effective community engagement for genomics research in Uganda.
4. To develop a framework for effective community engagement for genomics research in Uganda.

 Uganda 2022-03-30 2025-03-30 Social Science and Humanities Non-Clinical Trial Degree Award
Raymond Tweheyo
ID: UNCST-2020-R014507
 Development and validation of a Medical Internship Experience Scale (MIES) for low- and middle-income countries.
REFNo: HS2062ES

4.2 General Objective
To develop and validate the Medical Internship Experiences Scale in Uganda, so as to contribute to the understanding of internship experiences for the health workforce in low- and middle-income countries.
4.3 Specific Objectives
1) To draft a Medical Internship Experiences Scale (MIES) for testing in Uganda alongside other LMICs.
2) To develop and test the Medical Internship Experiences Scale (MIES) among intern doctors in Uganda.
3) To evaluate the experiences of intern doctors and 3-year post internship doctors with their medical internship, using the MIES in Uganda.
4) To explore the perceptions of intern doctors, and intern doctor supervisors regarding the wellbeing of intern doctors during the medical internship training in Uganda.

UK 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ANITA ARINDA
ID: UNCST-2020-R014158
 AN EDUCATION PROGRAM FOR IMPROVEMENT IN HIV KNOWLEDGE FOR ADOLESCENTS WITH INTELLECTUAL DISABILITY IN ENTEBBE, UGANDA
REFNo: HS2159ES

To estimate the retention of HIV knowledge and change in attitudes to HIV of adolescents with mild-to-moderate ID at 3 months following an HIV education program.,To estimate the change in HIV knowledge and attitudes of adolescents with mild-to-moderate ID following an HIV education program education intervention.,To determine the feasibility and acceptability of the HIV education program for adolescents with mild-to-moderate intellectual disability in Entebbe.,To conduct a pilot study of an HIV education intervention program for adolescents with mild-to-moderate intellectual disability (ID) and to assess its feasibility, acceptability and ability to increase HIV knowledge at baseline and 3 months.,
 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
REBECCA NANTANDA
ID: UNCST-2019-R001533
 Understanding the Strategies, policies and stakeholders perspectives on air quality management: towards improving air quality pollution in urban settings in Uganda.
REFNo: HS2097ES

To conduct a scoping review to synthesize air quality management strategies in Africa with a focus on who is involved, what works and why.

To assess the knowledge and perspectives of stakeholders whose roles influence air pollution and related health outcomes in Kampala and Jinja Cities.
 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bukenya Fred
ID:
Evaluation of a Public-Private Partnership project of indoor residual spraying on malaria prevalence in urban slum areas of Kampala
REFNo: HS2099ES

To evaluate the effectiveness of the PPP project vector control strategies (IRS) on: 1. malaria prevalence 2. trends in catchment area health facility malaria burden indicators (e.g. test positivity rates, proportion of malaria outpatient visits) before and after implementation of IRS in 8 urban/slum areas.
 Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dominic Bukenya Yiga
ID:
Comparison of perceptions of diabetes amongst Ugandans with low and high BMI: a qualitative study
REFNo: SS1200ES

i)To describe the perceptions of the causes of the diabetes and impact of the
condition in both rural and urban populations
ii) To compare and contrast the views of those with low BMI and high BMI
iii) To develop an understanding of the interactions between patients and their
healthcare providers and whether the information provided differs in relation
to their location and BM
The overall aim of this study is to investigate perceptions of diabetes amongst Ugandan
adults with type 2 diabetes with and without obesity, and those living in rural and urban
locations
 Uganda 2022-03-30 2025-03-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Ndungutse
ID: UNCST-2022-R011044
 BURDEN OF PNEUMOCOCCAL DISEASE AMONG CHILDREN BELOW FIVE YEARS OLD FOLLOWING PNEUMOCOCCAL CONJUGATE VACCINATION: ANALYSING LOCAL SURVEILLANCE DATA IN UGANDA
REFNo: HS2102ES

The project’s overall Goal is: To contribute to the understanding of the morbidity, mortality and disability due to Pneumococcal Disease among children below five years in Uganda. The project objectives;
1. Document the burden of pneumococcal disease (invasive and non-invasive) in under 5years old children in Uganda
2. Identify and determine the distribution of the pneumococcal serotypes in under-5yrs old children and the risk factors before, during and after PC Vaccination rollout in Uganda
3. Establish the PVC coverage rates by reviewing data pertaining vaccination and adverse events following immunization (AEFI) through using the available data source documents and reporting mechanisms.
4. Document the gaps in the surveillance data that need further intervention by comparing data available with standard case definitions

Uganda 2022-03-30 2025-03-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Fred Ssewamala
ID: UNCST-2020-R014060
 Suubi4Stronger Families: Addressing Child Behavioral Health by Strengthening Financial Stability and Parenting among Families in Uganda
REFNo: SS1205ES

The study examines the mechanisms by which economic empowerment (EE) and family strengthening (FS) interventions targeting social, familial and context-specific drivers affect childhood behavioral health.

Specific aims of the study are:

Aim 1: Examine the impact of EE only, MFG-based FS only, and combined EE+MFG-based FS on children’s DBD symptoms and behavioral functioning.

Aim 2: Test the influence of EE only, MFG-based FS only, and combined EE+MFG-based FS on family financial stability (e.g., food and housing stability, material assets, savings), parenting and protective family
processes (e.g., family organization, caregiver/child interaction, cohesion, support) and perceptions related to
help seeking (e.g., stigma) on CBH and functioning; and assess whether these change mechanism mediate intervention effects on DBD symptoms and behavioral functioning, and explore moderation by context specific moderators of intervention effects.

Aim 3: Qualitatively examine participants’ experiences with each intervention arm.
 Uganda 2022-03-30 2025-03-30 Social Science and Humanities Clinical Trial Non-degree Award
Julian Bagyendera Kobutungi
ID:
Endline Survey of the Education Response Plan for Refugees and Host Communities (ERP)
REFNo: SS1234ES

Establish inclusion and contextualization of the impact level indicators, as assessed through baseline 2.0 for which data was collected in March 2021.,vi. Assess percentage of teachers that have the professional competency required for implementing the programme ,Identify opportunities to improve both the cooperation and coordination between the key stakeholders and their support aimed at the improved delivery of the education services in a set of concrete and actionable recommendations. ,Identify lessons and good practices from the implementation of the ERP I. ,Assess the sustainability of the results achieved by the ERP at national and district levels.,ii. Assess the effectiveness and efficiency of the implementation of the ERP at national and district levels; also, but not exclusively, with regard to: - Achievements of the Plan regarding increase access to education, improve quality of education for both refugee and host community children. - Strengthening of the national and district systems for effective delivery of education services considering the COVID –19 impact. - Assess the extent to which issues of gender equality, and equity have been taken into consideration. Special attention will be given to learners with disabilities from both the refugee and host communities to ensure that access to school, teacher’s capacity (training, capacity to identify needs they may have, materials) and identification methods are assessed during the evaluation. ,i. Assess the relevance and coherence of the objectives and the approach of the ERP at national and district levels.,2) To assess and validate the results partners have achieved during the implementation period as a way to ensure and support accountability for ERP support. ,1) Provide information to support learning among key stakeholders from the experience of implementing the ERP at national and district levels, with a view to informing the ERP II and similar initiatives. ,
 Uganda 2022-03-29 2025-03-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stella Otai Auma
ID:
Is transparency rhetoric or reality? Organisational performance in the public health sector during the COVID-19 pandemic: evidence from Uganda
REFNo: SS1214ES

5. To ascertain how the outcomes of transparency impact organisational performance of the public health sector in Uganda and to propose evidence based areas for improvement including processes and tools ,4. To explore the impact transparency has on the health sector processes during the COVID-19 response. ,3. To scope the challenge which public health sector managers in Uganda have in maximizing transparency effectively. ,2. To map how the domains of transparency impacts on organisational processes in order to effectively maximise the role of transparency on in shaping organisational performance.,To map the domains that transparency impacts on and also its processes in order to effectively maximise the role of transparency on organisational performance.,To explore the impact transparency has on the health sector processes during COVID-19 response in order to ascertain how the outcomes of transparency impact organizational performance in the health sector in Uganda.,
 Uganda 2022-03-29 2025-03-29 Social Science and Humanities Non-Clinical Trial Degree Award
Samuel kirimunda
ID: UNCST-2021-R012738
 Childhood Burkitt Lymphoma survival rates in Uganda: A retrospective cohort study of histologically confirmed BL cases diagnosed between 2011 and 2015 in Northern Uganda
REFNo: HS2135ES

Main Objective
1. To determine if tumor stage at diagnosis, treatment protocol, and HLA class I & II allele genotype are associated with the five-year survival rate among children diagnosed with eBL in Uganda
Specific Objectives
1. To determine whether tumor staging at diagnosis is associated with survival among a retrospective cohort of eBL cases in northern Uganda.
2. To determine whether treatment protocols are associated with survival among a retrospective cohort of eBL cases in northern Uganda.
3. To determine whether HLA class I & II allele types are associated with survival among a retrospective cohort of eBL cases in northern Uganda.
 Uganda 2022-03-29 2025-03-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Matovu Nicholas
ID:
Colorectal cancer in Uganda: exploring prevention strategies
REFNo: HS1889ES

3. To investigate the knowledge and awareness of CRC, screening and barriers to biomedical presentation among the central Ugandan population through conducting a public cross-sectional survey (Study III),To investigate current challenges regarding the development and implementation of CRC prevention and screening strategies in Uganda through key informant interviews (Study II),To profile the epidemiology of CRC using data from the local Ugandan population-based cancer registries (Kampala and Gulu) (study 1),
 Uganda 2022-03-25 2025-03-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Christine Semambo Sempebwa
ID: UNCST-2021-R011977
 Higher Education Policy influence on Access and Resilience for South Sudanese students from Bidi Bidi settlement
REFNo: SS1186ES

2. To explore how refugee higher education policy practice influences HE access and resilience for South Sudanese refugees from Bidi Bidi settlement in Uganda.,1. To explore how refugee higher education policy formulation influences HE access and resilience for South Sudanese refugees from Bidi Bidi settlement in Uganda. ,To explore how refugee higher education policy influences higher education access and resilience for South Sudanese refugees from Bidi Bidi settlement in Uganda.,
 Uganda 2022-03-25 2025-03-25 Social Science and Humanities Non-Clinical Trial Degree Award
Stella Nassolo
ID:
Improving mental health and resilience among children living with HIV in Uganda.
REFNo: SS1197ES

The baseline will establish the current status of mental health and wellbeing of children living with HIV in target districts before being exposed to the Stepping Stones with Children approach (using the short or longer version of the manual) and the existing perceptions, knowledge, attitudes and practices surrounding mental health in the target districts.,To determine the baseline quality of mental health among children living with HIV in three selected districts of Uganda.,
 Uganda 2022-03-25 2025-03-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nathan Nshakira
ID:
Accountability mechanisms, practices and challenges for RMNCAH services in Uganda’s health sector
REFNo: HS598ES

a) Document and analyze the current definition and structuring of health accountability mechanisms (structures and processes) at the different levels of the Uganda health system;
b) Examine the processes, progress and results of health accountability implementation; and the factors influencing these at the different levels of the health system;
c) Describe the specific relationships and influences between current health accountability processes and results; and RMNCAH service delivery and utilization.
d) Generate recommendations for strengthening health accountability and enhancing its specific influence on RMNCAH service delivery, utilization and results.

 Uganda 2022-03-24 2025-03-24 Medical and Health Sciences Non-degree Award
Sharifah Nabambejja
ID:
Vitamin D levels and its potential role in COVID19 Pathogenesis in a Ugandan Population
REFNo: HS1572ES

1.To assess the serum Vitamin D3 levels in Uganda.
2.To establish the Ugandan reference range of Vitamin D3.


 Uganda 2022-03-24 2025-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Susan  Nabadda
ID: UNCST-2020-R014331
 COVID-19 rapid antigen test screening validation and diagnosis study in symptomatic and asymptomatic populations at border crossings in Uganda to support efficient testing practices
REFNo: HS2105ES

Secondary Objective 2 (Phase 1 and 2): Enhance truck driver awareness on COVID-19 symptoms, prevention and response.,(Phase 1): Provide evidence and advocate for policy change at a national level to: (a) permit Ag RDT COVID-19 screening in asymptomatic populations and (b) accept negative Ag RDT test results in asymptomatic individuals as proof they are not infected with COVID-19.,(Phase 2): Assess the feasibility, acceptability, efficiency, and cost-effectiveness of Ag RDTs for COVID-19 screening compared to RT-PCR testing in both symptomatic and asymptomatic individuals.,(Phase 1): Validate WHO EUL COVID-19 Ag RDTs for screening of asymptomatic truck drivers at border crossings (and optionally at a select site in Kampala) in Uganda.,
 Uganda 2022-03-24 2025-03-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kukunda Bacwayo Elizabeth
ID: UNCST-2021-R011603
 CONSPIRACY BELIEFS AND COVID-19 VACCINATION HESITANCY IN UGANDA
REFNo: SS1174ES

Objectives of study
(i) To measure the extent of the spread of conspiracy beliefs regarding vaccination against Covid-19 among Ugandans
(ii) To establish the relationship between conspiracy belief and vaccination hesitancy in Uganda;
(iii) To explore the interaction between exposure to COVID-19 conspiracy theories and individual vaccination decisions;
(iv) To examine the gendered impact of conspiracy belief on vaccination hesitancy; and
(v)To examine how the conspiracy beliefs of adults are likely to affect decision to vaccinate children for COVID-19.

Uganda 2022-03-23 2025-03-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Tophil Odoy Owino
ID:
HUMAN RESOURCE MANAGEMENT PRACTICES AND HEALTH SERVICE DELIVERY IN UGANDA: A CASE STUDY OF TORORO DISTRICT LOCAL GOVERNMENT HC IV.
REFNo: SS1005ES

1. Examine the influence of hiring practices on Health service delivery in TDLG HC IV.
2. Determine the influence of staff development practices on Health service delivery in TDLG HC IV.
3. Assess the influence of performance evaluation practices on Health service delivery in TDLG HC IV.

 Uganda 2022-03-22 2025-03-22 Social Science and Humanities Non-Clinical Trial Degree Award
Patience Kibbedi
ID:
Evaluating Positive Youth Development Intervention Programs Promoting Character Virtues AmongUgandan Youth Living in Poverty: Innovations using Idiographic Methods and Measures
REFNo: SS1110ES

To investigate methods and measures to capture the diverse and unique individual pathways towards character virtue development amongst Ugandan youth living in poverty
 Uganda 2022-03-22 2025-03-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
 Integrated Sexual and Reproductive Health & Rights Programme in High Burden Districts of Uganda (ISPHD) or HEROES4GTA Project: Evaluation Study Protocol
REFNo: SS1194ES

Main objective
1. The purpose of the study is to benchmark and monitor the status of key performance areas as defined in the program key outcome indicators; conduct a power mapping of stakeholders and service providers; carry out a gender and vulnerability analysis in relation to access/utilisation of improved Sexual Reproductive Health and Rights (SRHR) and Gender Based Violence (GBV) services; and to enhance sustainability measures of the programme.


Specific objectives:
i. Assess the level of knowledge, beliefs, perceptions, attitudes, and norms (empirical and normative) about SRHR and SGBV across key structures and beneficiaries in the ISPHD districts

ii. Establish baseline values for specific Programme key performance outcome indicators as stipulated in the ISPHD Programme Results framework.

iii. Establish the power dynamics and influence concerning the program overall objective – (stakeholder and power mapping) of stakeholders and service providers in the target districts.

iv. Establish the current level of commitment of key structures to gender equity and SRHR services. This should be based on the minimum intervention services package, capacity including the quality of services, resources, and protocols, among others.

v. Assess the extent of involvement of beneficiary groups in implementation, monitoring and improving services, satisfaction and/or perceptions of beneficiary groups about the quality of existing mechanisms in meeting their needs.

vi. Identify existing policies, laws, and ordinances and establish how these impact on power inequity in relation to SRHR and GBV service provision and utilization.

vii. Identify SGBV and SRHR inequality hot spots in the target districts to facilitate differentiated implementation and targeting.

viii. Assess the relevance, validity, and sustainability measures for the ISPHD program including validation of risks and assumptions concerning the Theory of Change(TOC)
 Uganda 2022-03-22 2025-03-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
David Kyaddondo
ID: UNCST-2020-R014906
 Enhancing Community Training for Student Mental Health Nurses in Uganda
REFNo: SS1199ES

1) Identify students’ class-based community nursing learning needs;
2) identify community MH nurse CPD support needs;
3) Plan a CPD curriculum deliverable online by educators at BPSN
 Uganda 2022-03-22 2025-03-22 Social Science and Humanities Non-Clinical Trial Non-degree Award
DAVID AGABA COLLINS
ID: UNCST-2019-R000301
 PREVALENCE OF AND FACTORS ASSOCIATED WITH ABNORMALOBSTETRIC SHOCK INDEX AMONG IMMEDIATE POST-PARTUMWOMEN AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS2138ES

1. To determine the prevalence of abnormal obstetric shock index among women in the immediate post-partum period following vaginal delivery at Mbarara Regional Referral Hospital
2. To determine the factors associated with abnormal obstetric shock index among women in the immediate post-partum period following vaginal delivery at Mbarara Regional Referral Hospital
 Uganda 2022-03-22 2025-03-22 Medical and Health Sciences Non-Clinical Trial Degree Award
Raymond Odokonyero Felix
ID: UNCST-2020-R014183
 ALCOHOL USE, GENDER, AND HIV IN UGANDA: YOUNG PEOPLE’S RISK OF HIV, LIVED EXPERIENCES, PROVIDERS’ PERCEPTIONS, AND FUTURE CARE OUTCOMES.
REFNo: HS2001ES

This study aims to: 1) Systematically review literature on the risk of HIV infection by gender among young people who use alcohol in Low and Middle Income Countries (LMIC); 2) Explore the lived experiences of alcohol use by gender among young people living with HIV (YPLH); 3) Explore the perceptions of HIV care providers regarding the care of young people living with HIV who use alcohol by gender; and 4) Determine the association between age at initiation of alcohol use and health related quality of life and viral suppression rates among PLWH in Southwestern Uganda.
Uganda 2022-03-21 2025-03-21 Medical and Health Sciences Non-Clinical Trial Degree Award
SIMON ARUNGA
ID: UNCST-2021-R013498
 Cluster randomised controlled trial of a complex intervention package to reduce blindness from severe microbial keratitis in Uganda.
REFNo: HS1814ES

To determine if a complex intervention package delivered at the Primary Health Centres (PHCs) including early recognition, prompt chlorhexidine 0.2% treatment and rapid referral can result in reduced rates of blindness from severe MK at three months
 Uganda 2022-03-21 2025-03-21 Medical and Health Sciences Clinical Trial Non-degree Award
Johanna  Blomgren
ID: UNCST-2021-R012309
 MIDWIZE - Strengthening midwives to implement and sustain quality improvements to optimise maternity care: A longitudinal observational study in Uganda
REFNo: HS1885ES

This PhD project aims to explore how midwives can take the lead in implementing or enhancing QI components within maternal health care in Uganda. The overall goal of this project is to improve the health of women and newborns. The way to achieve this is through enhancing the quality of care by capacitating midwives. Sub-study 1 - Co-creating and developing the intervention and the implementation Specific objectives: To explore multisectoral stakeholders' perspectives and ideas on how to strengthen midwives' capacity to implement QI components. To explore which QI components the midwives will implement or enhance. Sub-study 2 - Implementation and evaluating the sustainability of the implementation Specific objectives: -To measure the uptake of evidence-based QI components when midwives lead, organise and provide enhanced intra- and postpartum care. -To measure the long-term sustainability of the midwives' QI projects. Sub-study 3 – Process evaluation Specific objective: To evaluate the process of strengthening midwives' capacity to implement QIs in maternal care.
 Sweden 2022-03-21 2025-03-21 Medical and Health Sciences Clinical Trial Degree Award
John  Kirabira Baptist
ID:
Evaluation of nanoscale materials as candidate adjuvants and delivery systems for SARS CoV-2 subunit vaccine
REFNo: HS2103ES

a) To green synthesize and evaluate the physio-chemical properties of silver nanoparticles (AgNPs)
b) To design Lipid nanoparticle (LNP) and Chitosan nanoparticles (CNPs)
c) To develop nano adjuvant vaccine delivery system
d) To evaluate the immunogenicity of nano adjuvants (CNPs, LNPs and AgNPs) loaded with SARS CoV-2 sub-unit vaccine in mice.
e) To determine the safety of designed nano vaccine delivery systems using mice.

 Uganda 2022-03-21 2025-03-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano Kaleebu
ID: UNCST-2021-R013577
 A Randomized, Observer-Blind, Phase 2 Clinical Trial of COVAC-2 in Generally Healthy Adults
REFNo: HS2124ES

Primary Objective:
• To evaluate the safety and tolerability of the COVAC-2 vaccine (25 ?g dosing of S1 antigen) in generally healthy adults ages 18+.
Secondary Objectives:
• To determine spike-binding and pseudovirus neutralizing antibody responses against the Wuhan strain of SARS-CoV-2 induced by COVAC-2; and
• To determine a cellular immune response induced by COVAC-2.
Exploratory Objectives:
• To determine Receptor-Binding Domain (RBD)-binding antibody responses induced by COVAC-2; and
• To determine the neutralizing antibody response induced by COVAC-2 against one or more Variant(s) of Concern (VOC) and/or Variant(s) of Interest (VOI).


Uganda 2022-03-21 2025-03-21 Medical and Health Sciences Clinical Trial Non-degree Award
Richard Ntwari
ID: UNCST-2022-R004889
 Model for enhancing security in a Bring Your Own Device (BYOD) environments
REFNo: SIR40ES

The main objective: - To improve mobile devices security and integration in enterprises through the development of a security model for the usage of BYOD devices.


Specific Objectives

i.To identify key BYOD security issues and existing models through literature review with the aim of identifying their strengths, shortcomings, and functional requirements for the proposed model.

ii. To design a security model for usage of BYOD devices in SMEs through defining relationships of the components identified in objective I above.

iii. To examine the usability of the developed model through expert reviews to enable establish whether it provided satisfactory performance

 Uganda 2022-03-18 2025-03-18 Engineering and Technology Non-Clinical Trial Degree Award
Brenda Okech Apio
ID: UNCST-2022-R011031
 Using Implementation Research to Understand the Impact and Effectiveness of the Pediatric Breakthrough Partnership in Mozambique, Nigeria and Uganda.
REFNo: HS2119ES

Objective 1: To evaluate the acceptability and feasibility of the SDF implementation strategies used within the PBP.

Objective 2: To assess adoption of the SDF implementation strategies.

Objective 3: To document lessons learned to support potential scalability of the PBP and SDF.

The effectiveness objective of this study is to: Objective 4:
To assess the impact of the SDF implementation strategies on pediatric HIV outcomes as measured by the percent change in locating, testing and linking to care undiagnosed children, adolescents and pregnant women living with HIV before, during and after the PBP implementation

 Uganda 2022-03-18 2025-03-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Florence Tushemerirwe Basiimwa
ID: UNCST-2020-R014552
 The Extent and Nature of food advertising targeted to children and adolescents in Uganda (FACe-U Project)
REFNo: HS1990ES

General objective: To examine the extent, nature, attitudes and perceptions around food and non-alcoholic beverages advertised to children and adolescents in Uganda between January 2018 and December 2019. Specific objectives i. To identify and categorise advertising channels and types of food and non-alcoholic beverages advertised to children ii. To analyse the food and non-alcoholic beverages advertising content used to persuade children to consume advertised food on TV, radio, print media and outdoor school zones. iii. To describe the trends of food and non-alcoholic beverages advertising to children in Uganda. iv. To establish the association between children’s self-reported exposure to advertised foods and their nutritional status v. To explore children, parental and policy stakeholder attitudes and perceptions towards food and non-alcoholic beverages advertising to children
 Uganda 2022-03-17 2025-03-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Annet Kabanyoro Kasigwa
ID:
Innovative Teaching and Learning Strategies for Large Classes of Undergraduate Nursing Students in Uganda
REFNo: SS1142ES

4. Design innovative strategies that could guide teaching and learning for large classes of undergraduate nursing students in Uganda.,3. Identify the available strategies employed by nurse educators while teaching large classes of undergraduate nursing students.,2. Explore the challenges that undergraduate nursing students face while learning in large classes,1. Explore the challenges that nurse educators face while teaching large classes of undergraduate nursing students,The purpose of the study is to develop innovative strategies that could be used to enhance teaching and learning in large classes of undergraduate nursing students in Uganda.,
 Uganda 2022-03-17 2025-03-17 Social Science and Humanities Non-Clinical Trial Degree Award
Rhoda Wanyenze
ID: UNCST-2021-R013352
 Willingness for COVID-19 vaccination, adherence to non-pharmaceutical interventions and associated factors among adults in Uganda: a computer assisted telephone interview survey
REFNo: HS1742ES

To determine the influence of vaccine introduction on adherence to COVID-19 NPIs among adults in Uganda.,To determine the influence of trust on willingness to vaccinate and adherence to NPIs among adults in Uganda.,To determine the adherence to COVID-19 NPIs and associated factors among adults in Uganda.,To determine the willingness for COVID-19 vaccination and associated factors among adults in Uganda.,To assess willingness for COVID-19 vaccination, adherence to NPIs and associated factors including trust among adults in Uganda to identify strategies to improve uptake of these interventions for COVID-19 prevention and control. ,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Andrew Mujugira
ID: UNCST-2019-R000871
 Preventing Intimate Partner Violence and Improving HIV Outcomes in Kampala, Uganda
REFNo: HS1843ES

AIM 1: Assess the reach, effectiveness, adoption, implementation and maintenance of national IPV guidance in HIV treatment and prevention settings in Uganda. We will conduct a cross-sectional evaluation using programmatic data from health facilities engaged in the parent study in order to determine the extent to which current national IPV guidance is implemented alongside existing HIV treatment and prevention services.

AIM 2: Identify provider-level barriers and facilitators to implementing national IPV guidance within HIV treatment and prevention settings in Uganda. We will conduct in-depth interviews with HIV providers from health facilities engaged with the parent study. Qualitative data will be thematically analyzed to explore opportunities to optimize and adapt strategies to more effectively intervene upon IPV in HIV care settings.

 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Degree Award
Solomon Wafula Tsebeni
ID: UNCST-2021-R013883
 Healthcare workers’ Proficiency and Quality of Management for Snakebites in high burden Districts in Uganda
REFNo: HS2121ES

To explore the barriers faced in the management of snakebites in high burden districts in Uganda. ,To assess the quality of management for snakebites in high burden districts in Uganda.,• To assess the knowledge of health workers on snakebite management in two high burden districts in Uganda.,The overall objective is to assess health worker proficiency and quality of management of snakebites and associated barriers in high burden districts of Arua and Gulu so as to guide design of appropriate interventions to improve the quality of patient management and enhance favourable clinical outcomes. ,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joweria Nambooze
ID: UNCST-2019-R001118
 Socio-demographic inequities in the risk of and response to Covid-19 in Uganda: a comparison of slum and estate communities
REFNo: HS2059ES

To determine the associations of practice of preventive measures with key social-demographic factors and other study variables between slum communities and suburb resident,To assess the variation in Psychosocial and economic impacts of Covid-19 between slum communities and suburb resident,To determine the difference Knowledge, perceptions and access to Covid-19 information between slum communities and suburb resident,To assess the difference in adoption of Covid-19 preventive measures and access to health services between slum communities and suburb resident,To conduct a comparative analysis of slum dwellers with economically-advantaged communities,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 Integration of SARS-CoV-2 surveillance in the active and reactive screening activities of the Intensified Sleeping Sickness Elimination Program (ISSEP) in West Nile districts, Uganda
REFNo: HS2104ES

3. To demonstrate the feasibility of using a new tool to digitalize data capture and facilitate real-time data reporting of the HAT reactive and active community screening campaigns.,2. To conduct a serosurvey for antibodies against the SARS CoV-2 spike and nucleocapsid proteins to estimate the prevalence of community exposure.,1. To demonstrate the feasibility of integrating SARS-CoV-2 in the HAT reactive and active community screening campaigns to detect active symptomatic SARS-CoV-2 infection.,
 Uganda 2022-03-16 2025-03-16 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Uganda Gender and Tuberculosis Key Populations Assessment
REFNo: HS1864ES

1. To establish the gender differences evident in TB care cascade (diagnosis through treatment) records in Uganda. 2. To determine the gender barriers and facilitators to TB prevention, diagnosis, treatment and treatment completion in Uganda. 3. To generate information to guide the listing of TB KVPs relevant to Uganda context, and for designing interventions for addressing the gaps among prioritized KVPs. 4. To determine to what extent the National TB response (NSP and policies/guidelines) addresses gender and KVP issues in Uganda.
 Uganda 2022-03-14 2025-03-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pauline Byakika-Kibwika
ID: UNCST-2019-R001206
 Exposure-Response Evaluation of IV Artesunate in Children with Severe Malaria
REFNo: HS2027ES

Primary:
• To determine the relationship between dihydroartemisinin (DHA) exposures following intravenous dosing and markers of physiologic dysfunction associated with severe malaria
Secondary:
• To determine the relationship between DHA exposures and time to hospital discharge
• To determine the relationship between DHA exposures and parasite clearance associated with treatment of severe malaria.
Exploratory:
• To determine the relationship between DHA exposures and neurodevelopmental outcomes associated with treatment of severe malaria outcomes and explore predictors that may affect this relationship
• To evaluate the role of parasite clearance as a mediator of the relationship between DHA exposures and markers of physiologic dysfunction associated with severe malaria
• To develop a score comprised of markers of physiologic dysfunction and describe its relationship to clinical outcomes
• To assess P. falciparum infections for artemisinin resistance

Uganda 2022-03-14 2025-03-14 Medical and Health Sciences Clinical Trial Non-degree Award
Danielle Falk
ID:
Educators in Emergencies: The Lived Experiences and Professional Identities of Refugee and National Primary School Teachers in Uganda and South Sudan
REFNo: SS1213ES

To determine in what ways teachers conceptualize their professional identities,To understand how protracted conflict, forced displacement, and recurrent migration influences teachers’ lived experiences in their classrooms, schools, and communities in refugee-producing and receiving countries,To explore the lived experiences and professional identities of refugee and National Primary School Teachers in Uganda and South Sudan,
 USA 2022-03-14 2025-03-14 Social Science and Humanities Non-Clinical Trial Degree Award
Mathias Wambuzi
ID:
Community Engagement Strengthening for future HIV Vaccice trial participation in fishing communities around Entebbe,Uganda( CEVAC)
REFNo: SS1201ES

1. To assess knowledge on HIV vaccine trials among people living in FCs around Entebbe, Uganda.
2. To assess willingness to participate in future HIV vaccine trials among people living in FCs around Entebbe, Uganda.
3. To understand HIV vaccine trials experiences and motivators to participation among former participants.
4. To explore communities’ experiences, perceptions and preferences for community engagement among FCs around Entebbe, Uganda.

 Uganda 2022-03-11 2025-03-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Ambrose Oruni
ID:
Impact of escalating insecticide resistance on malaria control tools and parasite transmission in An. funestus from Uganda
REFNo: HS2063ES


i. Temporal monitoring of super-resistance every 6 months for 3 years. The frequency of the known resistance markers, changes in transcription profiles of resistance genes and variations in the genome will be monitored.

ii. Assess the impact of super-resistance on the effectiveness of the current and novel bednets against An. funestus.

iii. Assess the impact of super-resistance on malaria entomological transmission indices.

 Uganda 2022-03-11 2025-03-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Rahel Nkola
ID:
Depression, Suicidality and associated factors among people with Diabetes and/or Hypertension at a Tertiary Hospital in South Western Uganda.
REFNo: HS1818ES

To determine the prevalence and factors associated with Depression and Suicidality among individuals with DM and/or HTN at Mbarara Regional Referral Hospital, southwestern Uganda.
 Tanzania 2022-03-10 2025-03-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Cissy  Kityo
ID: UNCST-2021-R013663
 Rapid Proof-of-Principle Study: Diversity in the Spike gene of Sars Cov-2 and duration of SARS-Co-2 infection in immunologically compromised People Living with HIV-1
REFNo: HS2006ES

1.To characterize the SARS-CoV-2 virus found in HIV positive patients
2.To assess the impact of HIV immunosuppression on SARS-CoV-2 diversity
3.Determining the duration of SARS-CoV-2 infection in HIV infection
Uganda 2022-03-10 2025-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Alison Kinengyere Annet
ID:
Communication of research findings: a case study of medical researchers at the College of Health sciences, Makerere University
REFNo: HS2030ES

To assess the facilitators and barriers of medical research communication by researchers at MAKCHS.,To develop video documentaries, cartoons, podcasts, webinars and research briefs to communicate research findings of selected research studies at the college of health Sciences, Makerere University,To assess the factors associated with communication of medical research findings by researchers at the college of health sciences, Makerere University,To determine communication channels used by Makerere University College of Health sciences (MAKCHS) researchers in disseminating their research findings ,To investigate communication of medical research findings to different stakeholders by researchers at the college of health sciences, Makerere University,
 Uganda 2022-03-10 2025-03-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ruth Nanyonga
ID:
The Impact of Health Cooperative Membership on Health Agency and Economic Status of Women in Uganda’ Study
REFNo: SS1121ES

The main objective of the study is to quantify the impact of health cooperative membership on women’s health agency and economic status. The specific objectives include:

1. The health care access
• Safe delivery/pre-natal care
• Access to health trainings/education
• Access to regular primary care/check-ups

2. The health knowledge level
• Knowledge about health care resources (location of nearest clinic, where to get information regarding health)
• Knowledge about health itself (self-efficacy)
• Knowledge about insurance

3. The ability to set goals
• Preference to have a role in making the decisions about family planning?
• Preference to make the decision about when to seek health care for yourself?
• Preference to have a role in making the decisions about seeking health care for your family members/children?

4. Perceived ability and control
a. Ability to make decisions about family planning
b. Ability to make the decision to seek health care without delay
c. Ability to make decisions to seek health care for family members/children without delay

5. Action taken
a. Demonstrated decision-making power to seek health care without delay
b. Demonstrated decision-making power about family planning
c. Demonstrated decision-making power in seeking health care for family/children

 Uganda 2022-03-09 2025-03-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Dianah Aharimpisya
ID: UNCST-2021-R012528
 Elder Abuse and Welfare Status: Interrogating the deterrent gerontological mechanisms. A case of selected districts in south-western Uganda.
REFNo: SS1015ES

1. To examine the effect of elder abuse on welfare status in 5 selected districts of south-western Uganda. 2. To examine the mediating role of quality relationships on the association between elder abuse and welfare status in 5 selected districts of south-western Uganda. 3. To analyse the mediating effect of gerontological services access on the relationship between elder abuse and welfare status in 5 selected districts of western Uganda.
Uganda 2022-03-07 2025-03-07 Social Science and Humanities Non-Clinical Trial Degree Award
Divya Rayamajhi
ID:
Child and Adolescent mental health services in Uganda
REFNo: HS1786ES

i. To explore the availability of child and adolescent mental health services (CAMHS) in health facilities of Mbale district. ii. To identify barriers that may prevent people from accessing child and adolescent mental health services in Mbale from the perspective of health care providers. iii. To identify possible solutions to those barriers which may encourage or improve people`s access to child and adolescent`s mental health services in Mbale from the perspective of health care providers.
 Nepal 2022-03-07 2025-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Agnes Rwashana Semwanga
ID:
A WEB-BASED HISTOPATHOLOGY REPOSITORY SYSTEM FOR BREAST CANCER MANAGEMENT
REFNo: HS2002ES

To validate the slides to establish the intra and inter observer agreement in morphological assessment of breast core cancer cases using glass slides and digital slides.,To establish the requirements and develop a web-based Histopathology Repository System (NHRS) for breast cancer case,To digitize core breast cancer glass slides for morphological assessment of core breast cancer cases.,To develop a national digital histopathology reporting system storing digitized slides for assessment of morphological characteristics of core breast cancer.,
 Uganda 2022-03-07 2025-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phillip Wanduru
ID: UNCST-2019-R000381
 Determining short and medium-term sequelae, their predicting factors, and experiences of caring for newborns with intrapartum hypoxic-ischemic insults: Studies in Eastern rural Uganda
REFNo: HS2057ES

To understand caregivers’ experiences of caring for newborns with encephalopathy.,To determine the risk, and predicting factors of NDD at 6 and 12 months of age among infants who survived hypoxic-ischemic insults at birth.,To understand the interaction between healthcare providers and caregivers in the Newborn Care Units (NCU) when caring for newborns with hypoxic-ischemic insults at two high-volume hospitals in Eastern Central Uganda,To determine the predicting factors of hypoxic-ischemic insults and encephalopathy among newborns at two high-volume hospitals in Eastern Central Uganda,
 Uganda 2022-03-07 2025-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Sarah Kiguli
ID: UNCST-2021-R013020
 Sickle Pan-African Research Consortium (SPARCO) Uganda: Strengthening Capacity for Clinical Care, Research and Training in Sickle Cell Disease - SCRT Project.
REFNo: HS2012ES

The overall goal of the project is to join and become one of the sites of the Collaborative Consortium of the SCD in Sub-Saharan Africa Network (SPARCO) with a goal of strengthening capacity for clinical care research and training in sickle cell disease in Uganda through implementation of evidence-based interventions. We shall do this by: Aim 1: Developing a centralized, electronic, patient consented, sickle hemoglobinopathy registry for Uganda. AIM 2: To improve SCD patient outcomes in Uganda by establishing regional SCD standards of care. AIM 3. To advance SCD related research by conducting cohort studies and implementation science studies on patients enrolled in the SCD registry, and an additional study on transition from pediatric to adult care by SCD adolescents.
 Uganda 2022-03-07 2025-03-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Emma Riley-Green
ID:
Financial Diaries Uganda
REFNo: SS1178ES

Test if taking women through a report on their business highlighting areas of improvement and a comparison to similar businesses results in additional improvements in business outcomes,Test if the act of frequently asking the women about aspects of their businesses makes these dimensions more salient and results in improvements in business outcomes,Understand more about female-owned microenterprises using high-frequency data collected in the form of diaries.,To examine the impact of financial diaries for female entrepreneurs, with and without reports and comparisons to similar businesses, on a range of business outcomes.,
 UK 2022-03-07 2025-03-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Mwangi Fridah Gakii
ID:
PREVALENCE OF DYSLIPIDEMIA AMONG WOMEN WITH PRECANCEROUS AND CANCEROUS LESIONS ATTENDING CERVICAL CANCER CLINIC AT UGANDA CANCER INSTITUTE
REFNo: HS2087ES

General objectives
1. To determine the prevalence of dyslipidemia and its association with precancerous and cancerous lesions among women attending cervical cancer clinic at Uganda Cancer Institute for screening
Specific objectives
1. To determine the prevalence of dyslipidemia among women with precancerous and cancerous
lesions attending cervical cancer clinic at Uganda Cancer Institute for screening.
2. To determine the association between dyslipidemia, and grades of precancerous lesions among women attending cervical cancer clinic at Uganda Cancer Institute for screening.
3. To determine the association between dyslipidemia and grades of cancerous lesions among women attending cervical cancer clinic at Uganda Cancer Institute for screening
 Kenya 2022-03-07 2025-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Michael  Ediau
ID:
Stakeholders’ perspectives on early infant male circumcision for HIV prevention in a traditionally non-circumcising community in Northeastern Uganda
REFNo: HS2109ES

To explore the stakeholders’ perspectives on the feasibility of introducing and scaling up EIMC in Katakwi and Soroti districts, traditionally non-circumcising communities – northeastern Uganda,To assess the health system-related facilitators and barriers for introduction and scale-up of EIMC for HIV prevention in Katakwi and Soroti districts, traditionally non-circumcising communities – northeastern Uganda,To explore the health workers individual-level and parents’ related perspectives regarding EIMC for HIV prevention in Katakwi and Soroti districts,To explore the knowledge, attitudes, norms, behavior control, intention and experiences on EIMC for HIV prevention among parents of male children in Katakwi and Soroti districts, traditionally non-circumcising communities – northeastern Uganda,To explore stakeholders’ perspectives on early infant male circumcision for HIV prevention in Katakwi and Soroti districts, traditionally non-circumcising communities – northeastern Uganda,
 Uganda 2022-03-07 2025-03-07 Medical and Health Sciences Non-Clinical Trial Degree Award
Florence Ndagire
ID:
Access to Maternal, sexual and reproductive health for persons with disabilities in Uganda
REFNo: SS1062ES

The aim of this study is to conduct empirical research on access to maternal, sexual and reproductive health services for persons with disabilities in Uganda to ascertain whether the services, programmes and policies are inclusive of persons with disabilities.
Specific objectives
1. To analyse the legal and policy framework on access to maternal, sexual and reproductive health services to ascertain whether they mainstream reproductive health needs of persons with disabilities in Uganda.
2. To assess the barriers faced by persons with disabilities in accessing MSRH services.
3. To examine the lived experiences of persons with disabilities in accessing MSRH services.
4. To assess the effects of COVID 19 on access to maternal, sexual and reproductive health services by persons with disabilities in Uganda.

 Uganda 2022-03-04 2025-03-04 Social Science and Humanities Non-Clinical Trial Degree Award
Justus Atwijukire
ID:
Understanding the context in which it is profitable for various vanilla agricultural market actors to invest in stronger relationships and adopt product quality standards to meet the needs of higher-value markets
REFNo: A185ES

Identify the context in which it is profitable for agricultural actors, particularly producers and processors, to comply with and invest in higher product quality standards.,Assess the types of market linkages that best enable multinationals to collaborate with emerging agricultural markets to increase efficiency and effectiveness along the value chain in a mutually beneficial manner.,Evaluate the extent to which strengthening linkages and relationships between supply chain actors increasing horizontal and vertical market linkages among agricultural actors at various levels (companies, SMEs, smallholders, and intermediaries) promote economic benefits for the different actors and market expansion. ,To understand how existing vanilla supply chains in Uganda and targeted interventions designed to strengthen relationships between market actors affect production, quality, market access, profits and investment within supply chains. ,
 Uganda 2022-03-03 2025-03-03 Agricultural Sciences Non-Clinical Trial Non-degree Award
ALEX KAYONGO
ID: UNCST-2019-R001641
 In-vitro Susceptibility of Broncho-alveolar-derived Macrophages to Mycobacterium tuberculosis among persistently IGRA-negative TB household contacts in Uganda
REFNo: HS1767ES

Study Aim:
Phenotypic characterization of persistently IGRA-negative individuals based on in-vitro killing of luciferase-expressing recombinant Mtb in broncho-alveolar lavage.

Specific Objectives
1. To demonstrate in-vitro BAL and blood monocyte derived macrophage killing of luciferase-expressing recombinant Mtb among persistently IGRA-negative individuals.

2. To validate in-vitro BAL-derived macrophage killing assays using virulent Mtb strains identified from “the Ugandan TB cohort.

3. To compare BAL-derived macrophage expression profiles for selected cytokines, phagocytic receptors, phagosome maturation and microbial killing genes between IGRA-negative and positive individuals.

4. To compare levels of selected macrophage cytokines and chemokines in BAL supernatant between IGRA-negative and positive individuals.
 Uganda 2022-03-03 2025-03-03 Medical and Health Sciences Non-Clinical Trial Degree Award
Charlotte Brown Louise
ID: UNCST-2021-R012078
 Local urban initiatives for displaced populations in Gulu and Arua cities in Uganda
REFNo: SS1167ES

To understand the role of locally situated actors in protection for refugees and asylum seekers
To understand refugees' experiences of urban life and different forms of protection in urban areas
To explore how local actors understand 'protection'
To understand how locally situated actors understand their role in relation to Uganda's national refugee response framework
To produce learning materials to inform policy responses in other cities experiencing displacement
To disseminate findings to support to local discussions of refugee integration
 UK 2022-03-03 2025-03-03 Social Science and Humanities Non-Clinical Trial Degree Award
RACHEAL ALINAITWE
ID: UNCST-2020-R014509
 Detection and referral of depression among adolescents living with HIV in Uganda
REFNo: HS2055ES

• To determine whether depression is screened for among adolescents living with HIV in care • To assess the effect of self-assessment by adolescents on the rate of detection of depression • To determine reasons for failure to access care for depression among adolescents living with HIV at the referral point
Uganda 2022-03-03 2025-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jonathan Kayondo
ID: UNCST-2021-R008325
 Target Malaria Protocol A1: Entomological Studies To Characterize Field Sites In Uganda To Support The Evaluation Of Novel Mosquito-Targeted Malaria-Control Methods
REFNo: HS1884ES

1. To characterize malaria vector species composition and abundance in selected study sites, other mosquitoes present and the ancillary fauna of larval habitats.
\r\n2. To support insectary colony (wild-type) establishment/replenishment and insecticide resistance surveys.
\r\n3. Geographical and meteorological characterization of field sites.
\r\n
 Uganda 2022-03-03 2025-03-03 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
 ‘SD Biosensor STANDARD™ M10 SARS-COV-2’ – Diagnostic sensitivity and diagnostic specificity
REFNo: HS2100ES

establish the diagnostic sensitivity and diagnostic specificity of the STANDARD™ M10 SARS-CoV-2 test according to the WHO Instructions and requirements for Emergency Use Listing (EUL) Submission: In vitro diagnostics detecting SARS-CoV-2 nucleic acid or antigen, version 5; 02 June 2021, and to provide data to demonstrate the product is safe and effective for its intended use.,
 Uganda 2022-03-02 2025-03-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tom  Ngabirano Denis
ID: UNCST-2020-R014491
 Adapting and Validating the STARx Transition Readiness Questionnaire for Ugandan Young People Living with HIV/AIDs (YPLHIV) and their Parents
REFNo: SS1134ES

To understand the impact of COVID-19 on the health and well-being of YPLHIV,To validate the Event History Calendar (EHC) which was previously developed with Ugandan youth,To modify and validate The STARx, a transition tool for Ugandan youth,Our primary aim is to modify and validate a transition tool for Ugandan youth for use in transition from adolescent to adult HIV Care. ,
 Uganda 2022-02-28 2025-02-28 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jonathan Kayondo
ID: UNCST-2021-R008325
 Target Malaria Protocol C1: Stakeholder Engagement Protocol for Target Malaria Activities in Uganda
REFNo: HS1890ES

1. Co-developing the project pathway with stakeholders directly affected by the project and ensuring that all steps of the project receive appropriate community acceptance (in addition to regulatory approval) before they are implemented. 2. Building an enabling environment in which potential beneficiaries are at the heart of the decision-making process. 3. Position genetic approaches as a potential credible complementary tool to fight malaria and creating an enabling environment for its evaluation. 4. Ensure consent/community acceptance for field entomological and insectary activities (please refer to protocols on entomological and Insectary activities). 5. Collect stakeholder knowledge and expectations to inform and improve project activity implementation.
Uganda 2022-02-28 2025-02-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
 Lung Cancer in East Africa in Relation to HIV-1 Infection: Epidemiological, Molecular Characterization and Imaging (LCH Study)
REFNo: HS1922ES

1. To determine the clinical epidemiology of lung cancer and its relationship to HIV-1 infection in Uganda and Tanzania. 2. To determine the molecular determinants of lung cancer in HIV infected and uninfected individuals in Uganda and Tanzania 3. To Characterize Lung Cancer in HIV infected and uninfected populations in Uganda and Tanzania using Artificial Intelligence.
 Uganda 2022-02-28 2025-02-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joseph Ngonzi
ID: UNCST-2019-R001579
 Automated visual evaluation and geospatial mapping for cervical cancer screening optimization in sub-Saharan Africa (AVE-Map)
REFNo: HS2069ES

3. To use AVE and geospatial analysis to scale up cervical cancer screening in Uganda ,2. To determine access to cervical cancer screening and referral pathways in Uganda ,1. To validate and expand use of AVE for cervical cancer screening in SSA ,We aim to leverage and develop data science expertise at our sites to first optimize and then combine AVE-based screening by health workers at peripheral health facilities with geospatial-analysis and needs-driven assessment to inform scale-up of cervical cancer screening in Uganda ,
 Uganda 2022-02-28 2025-02-28 Medical and Health Sciences Clinical Trial Non-degree Award
Richard Cartland
ID:
Techno-economic Analysis of Solar Photovoltaic Mini-grids for Enhancement of Sustainable Livelihoods of Remote Communities: Case Study Uganda
REFNo: SIR97ES

iv. To develop a tool for assessing the sustainable livelihoods of communities supplied by power from renewable energy-based mini-grids,iii. To carry out economic modelling and simulation of the operation and performance of solar photovoltaic mini-grids versus other competing options ,ii. To analyze the technical operation of solar PV mini-grids in the context of developing nations,i. To analyze the development and installations of Renewable energy-based mini-grids in Uganda,To assess how sustainable livelihood of remote communities is enhanced through the use of solar PV based mini-grids and other competing options.,
 Uganda 2022-02-28 2025-02-28 Engineering and Technology Non-Clinical Trial Degree Award
GODFREY ASIIMWE BERINDE
ID:
Public Services, Security and the Legacy of Pre-colonial States in Uganda
REFNo: SS917ES

1) examine how the legacy of pre-colonial states shapes citizens’ willingness to contribute to public services in Uganda today, focusing on crime prevention and security services
2) examine the underlying mechanisms, focusing on persistence in culture and institutions.
Uganda 2022-02-24 2025-02-24 Social Science and Humanities Non-Clinical Trial Non-degree Award
DeeAnn Reeder Marie
ID: UNCST-2021-R012240
 Tolerance and resistance responses of African bats to viral antigens: Immunological tradeoffs in zoonotic reservoir hosts.
REFNo: NS300ES

The overall goals of the proposed work are (1) to understand the role that infection tolerance plays in the ability of African bat species to serve as reservoir hosts for virulent zoonotic viruses (especially Ebola), and (2) identify the molecular and behavioral mechanisms that contribute to these tolerance phenotypes.


 USA 2022-02-24 2025-02-24 Natural Sciences Non-Clinical Trial Non-degree Award
Eliot Atekwana Anong
ID:
Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS322ES

Our project objectives are to (1) map the lithospheric and mantle structure below segments of the rift in the northern Western Branch, (2) map magma melt depth, thickness and spatial distribution along the rift, (3) map the rift and fault architecture and determine their relationship to rifting, (4) determine fault communication with deep magma sources via volatiles and gas chemistries, (5) provide constraints on surface motions and rift opening rates from GPS measurements, and (6) test the three hypotheses with numerical models. During this project we will:
1. Use magnetotellurics (MT), gravity and passive source seismology to determine variations in lithospheric thickness, mantle-flow or frozen lithospheric anisotropy, and to assess the presence or absence of melt at depth.
2. Use magnetics, gravity, and seismology to determine the thermal structure and thickness of the crust beneath the rift zone.
3. Constrain surface motions with new GNSS observations.
4. Collect geomorphic samples for Quaternary geochronology for landforms cut and offset by the rift-bounding faults to determine their fault slip rates.
5. Use industry seismic reflection data acquired over the Albertine-Rhino graben to investigate fault evolution and strain migration through time.
6. Conduct field observations to examine the geometry and kinematics of rift related structures for the Albertine-Rhino Graben and Precambrian structures to evaluate the possible presence of a Precambrian suture zone that was reactivated during rift evolution.
7. Use the geochemistry of hot springs and measurements of magmatic gas fluxes along the border faults to establish the presence or absence of shallow magma chambers and the presence of magmatic volatiles-assisted faulting, while also quantifying variability of tectonic CO2 flux to the atmosphere from the northern Western Branch of EARS
8. Incorporate the above observations into a geodynamic model that test hypotheses about the role of melts beneath magma-poor rifts and how variations in lithospheric thickness and asthenospheric flow or the properties of the lithosphere relate to strain localization.
The different rift basins of the northern segment of the Western Branch of EARS exhibit distinct geomorphological features from south to north that are probably controlled by processes operating in the asthenosphere and lithosphere. Thus, a field experiment designed to investigate the along axis variability of the lithosphere and upper mantle structure along this entire segment from Lake Edward in the south to the Rhino graben in the north and its termination against the Aswa Shear Zone will provide critical insights on geodynamic processes operating in the asthenosphere, lithosphere, and at the surface which drive magma poor rifting.
USA 2022-02-24 2025-02-24 Natural Sciences Non-Clinical Trial Non-degree Award
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