Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
NELSON NSEREKO
ID:
FROM STANDARD SWAHILI TO THE SWAHILI VARIETY SPOKEN IN UGANDA: EVOLUTION AND MORPHOSYNTACTIC VARIATIONS
REFNo: SS2348ES

i) Describe the morphosyntax of the Kiswahili variety spoken in Uganda
ii) Compare and contrast the morphosyntax of Standard Kiswahili with that of the
Kiswahili spoken in Uganda
iii) Account for the emergence of the Kiswahili variety spoken in Uganda

Uganda 2024-02-26 13:35:31 2027-02-26 Social Science and Humanities Non-Clinical Trial Degree Award
Julian Adong
ID: UNCST-2021-R013487
Retention through mHealth for adolescents and young adults with HIV in care
REFNo: HS3722ES

Test the acceptability, feasibility, and preliminary impact of the developed adolescent-tailored mHealth intervention for retention in care of AYWH who are new to or newly re-engaging in care,Iteratively develop a social media-based adolescent-tailored mHealth intervention to improve retention in care for AYWH who are new or newly re-engaging in care,Define the cognitive, environmental, and behavioural challenges and their impact on behavioural intention for AYWH who are new or newly re-engaging in HIV care,To develop and test an mHealth intervention for retention in care for adolescents and young adults with HIV,
Uganda 2024-02-26 13:34:00 2027-02-26 Medical and Health Sciences Clinical Trial Non-degree Award
alfred andama andama
ID: UNCST-2022-R011051
TONGUE SWAB TUBERCULOSIS DIAGNOSTIC YIELD STUDY
REFNo: HS3761ES

Aim 1. To determine the proportion of people presenting to primary health centers with signs and symptoms of TB who: a. can provide a sample for TB testing (sputum vs. tongue swab) b. have a valid molecular test result (sputum vs. tongue swab) c. are detected as TB-positive (sputum vs. tongue swab) d. prefer providing a sputum vs. tongue swab sample
Uganda 2024-02-26 13:32:44 2027-02-26 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Bruce Kirenga J
ID: UNCST-2019-R001460
SOLIDARITY TRIAL-A phase I/II Randomized Placebo controlled trial to evaluate the Safety and Immunogenicity of Sudan Ebolavirus in Uganda
REFNo: HS3190ES

Phase I (rVSV-SUDV)
1. To determine the safety of rVSV-SUDV candidate SUDV vaccine among adult healthy volunteers in Uganda.
2. To determine the immunogenicity of rVSV-SUDV candidate SUDV vaccine.

Phase II (ChAdox1, CAd3 and rVSV-SUDV)
Primary objectives
1. To determine the safety of ChAdox1, CAd3 and rVSV-SUDV candidate SUDV vaccines among healthy volunteers and persons with stable comorbidities.
2. To determine the immunogenicity of ChAdox1, CAd3 and rVSV-SUDV candidate SUDV vaccines.
Secondary objectives
1. To determine the durability of SUDV-specific induced immune responses following vaccination.
2. To determine the factors associated with optimal vaccine-induced immune responses.
3. To determine the putative cross reactivity by the SUDV vaccine candidates against other ebolaviruses (e.g. Bundibugyo ebolavirus (BUDV) and EBOV).

Exploratory objectives
1. To determine the effect of SUDV vaccines on host gene expression.
2. To determine the T and B cell specific responses and immune profiling in response to vaccination.
3. To determine the effect of SUDV vaccines on the host metabolome.
4. To determine the effect of SUDV vaccines on host innate immune responses.

Uganda 2024-02-26 13:31:25 2027-02-26 Medical and Health Sciences Clinical Trial Non-degree Award
Rhona Mijumbi M
ID: UNCST-2023-R006843
Building a Culture of Evidence-informed Policy-Making in Uganda (B-CuE)
REFNo: SS2257ES

3) To improve collaboration for better coordinated and complementary support to EIDM in Uganda.,2) To design a sustainable and relevant capacity-building program for pre- and in-service training to ensure individuals and institutions acquire relevant and adequate knowledge and skills to support timely EIDM.,1) To scale-up the activities of the Center for Rapid Evidence Synthesis as a knowledge brokerage institution to strengthen support for timely EIDM in Uganda.,
Uganda 2024-02-26 13:23:45 2027-02-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
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