Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Eve  Namisango
ID: UNCST-2021-R014038
 Health Systems Strengthening through person-centred care: development of a feasible and acceptable theory-based workforce approach to improve quality
REFNo: HS1000ES

i) To adapt the conceptual framework of person-centred care for serious illness (MONTHS 1-10).
ii) To determine professional views on the feasibility, acceptability and necessary requirements for health systems change to deliver person-centred and values-based care (MONTHS 11-12).
iii) To design a systems-oriented strategy to enhance the person-centredness of care based on evidence from objectives i+ii (MONTHS 13-16).
iv) To refine and determine psychometric properties of a brief measure of person-centredness for subsequent evaluation of the health systems strengthening strategy (MONTHS 17-24).

Uganda 2021-02-04 2024-02-04 Medical and Health Sciences Non-degree Award
Nathan Fiala
ID: UNCST-2022-R009060
 “An exploration of groundnut Seed Quality Along the distribution chain in Uganda.”
REFNo: A109ES

The general objective of this study is to conduct an analysis of seed quality along the supply chain of groundnuts in Uganda. The selected crop for this study is important and the seed system is largely informal. Groundnuts is nearly 100% self-pollinating (98-99%) and farmers keep the seeds often beyond the recommended replacement period.
 USA 2021-02-04 2024-02-04 Agricultural Sciences Non-degree Award
Aloysius Ssennyonjo Ssennyonjo
ID: UNCST-2021-R013504
 COVID-19 Lockdown in Slums Informal Urban Settlements: Social and- Health Effects, Coping Strategies and Lessons for Improving the Livelihood of the Urban Poor in Kisenyi, Kampala, Uganda
REFNo: HS887ES

General Objective
To explore the social and health effects of COVID-19 lockdown, coping strategies and lessons for improving the livelihood of the urban poor in Kisenyi, Kampala, Uganda
Specific Objectives

1. To assess the immediate health effects of COVID 19 lockdown among the urban poor in Kampala
2. To assess the immediate social effects of COVID 19 lockdown among the urban poor in Kampala
3. To explore how the urban poor households coped with selected effects of the COVID-19 lockdown
4. To explore lessons for mitigating the effects of COVID 19 lockdown in the immediate recovery phase and consider implications for long term programming for urban poor.

 Uganda 2021-02-02 2024-02-02 Medical and Health Sciences Non-degree Award
Julius Tumusiime
ID:
Dynamics of Snail Species and Interventions to Reduce associated Schistosoma and Fasciola Parasitic Infections: A Citizen Scientists’ approach in Western Uganda
REFNo: NS148ES

1. determining the diversity and spatial-temporal distribution of freshwater snail intermediate hosts of Schistosoma/Fasciola parasites.
2. evaluating the diversity of Schistosoma/Fasciola trematodes shed per snail host: comparison of traditional and molecular methods.
3. examining the biotic (macrophyte, vertebrate hosts) and abiotic (rainfall, pH, DO, EC, temperature, inorganic ions) factors that influence the occurrence of Schistosoma/Fasciola snail hosts.
4. assessing the dependability/reliability of citizen researchers’ malacological survey, snail species identification and disease risk hotspot identification.

Uganda 2021-01-29 2024-01-29 Natural Sciences Degree Award
Alex Saturday
ID: UNCST-2023-R007459
 INVESTIGATION OF SPATIO-TEMPORAL VARIATION IN BIOLOGICAL AND PHYSICO-CHEMICAL WATER QUALITY PARAMETERS IN LAKE BUNYONYI, SOUTH-WESTERN UGANDA
REFNo: NS149ES

i. To determine the Spatio-temporal variations of bacterial fecal indicators of water in Lake Bunyonyi.
ii. To assess the Spatio-temporal variations in phytoplankton composition and biomass in the water of Lake Bunyonyi.
iii. To determine the Spatio-temporal variations of physicochemical quality of water in Lake Bunyonyi.
iv. To examine the seasonal variations of the trophic state conditions of Lake Bunyonyi ecosystem
v. To investigate the processes that governs nutrient dynamics in Lake Bunyonyi ecosystem.

Uganda 2021-01-28 2024-01-28 Natural Sciences Degree Award
Emily Otali
ID:
A study of health and forage patterns of wild African honeybees (Apis mellifera scutellata) and their impact on the survival of Kibale National Park, its threatened chimpanzees and elephants.
REFNo: A82ES

The general objective for this study is to engage farmers and students living around Kibale National Park, Uganda, in an accessible and culturally relevant participatory science project that collects and analyzes data measuring colony health and foraging plants of wild African honeybees for a period of two years. This will be achieved through:
• Developing participatory science project appropriate for rural Ugandan farmers and partnering students.
• Establishing baseline colony health and forage patterns for the wild African honey bee in the Kibale National Park ecosystem.
• Determining if colony health and forage patterns for the wild African honey bee knowledge will help achieve maximum honey yields and increased forage diversity.

 Uganda 2021-01-28 2024-01-28 Agricultural Sciences Non-degree Award
Jackson Mukonzo
ID: UNCST-2021-R013916
 IDENTIFICATION, VALIDATION AND OPTIMIZATION OF AVAILABLE DRUG MOLECULES FOR CLINICAL TREATMENT OF COVID-19.-IVCOM
REFNo: HS1065ES

1. Explore the clinical use of combination anticoagulant: lower dose aspirin and ivermectin, an FDA-approved anti-parasitic drug therapy in treatment of COVID-19 patients in an exploratory randomized trial.
2. To identify target molecules through testing and screening for SARS-CoV-2 activity of existing substances, molecules or formulations on basis of registered activity claims or scientific evidence for anti- SARS-CoV-2 activity including herbal preparations, quinolone derivatives (chloroquine and hydroxyquinoline) in combination with zinc, HIV entry and protease inhibitors, HCV protease inhibitors and entry inhibitors as well as agents with inhibitory and down regulatory effect on ACE2 and those that might be identified thorough literature search.
3. Use bioinformatics tools to perform structural optimization of molecules identified in objective 2 above for efficacy and safety of COVID-19 patents and conduct early phase clinical trials on the resulting molecules.
Uganda 2021-01-28 2024-01-28 Medical and Health Sciences Non-degree Award
Alex Mabirizi
ID:
ASSESING THE EFFECT OF CONCURRENT VACCINE ADMINISTRATION FOR PESTE DES PETITS RUMINANTS, CAPRIPOX AND CONTAGIOUS CAPRINE PLEUROPNEUMONIA ON IMMUNITY OF SHEEP AND GOATS IN UGANDA
REFNo: A106ES

1. To determine antibody titres against PPR, CCPP and Capripox Virus following single and concurrent administration of two or three vaccines.
2. To determine cytokine responses to PPR, CCPP and Capripox Virus following single and concurrent administration of two or three vaccines.

Uganda 2021-01-28 2024-01-28 Agricultural Sciences Degree Award
faith mbabazi musinguzi
ID:
Role conflict and Burnout among university administrators in selected universities in Uganda
REFNo: SS552ES

4. To assess the influence of role conflict on burnout for administrators across universities.,3. To establish the administrators’ experience with role conflict and burnout among administrators.,2. 2. To examine the degree to which role conflict constructs predict burnout among non-academic administrators.,1.To establish the extent to which role conflict constructs predict burnout among academic administrators.,
 Uganda 2021-01-27 2024-01-27 Social Science and Humanities Degree Award
Ponsiano Ocama
ID: UNCST-2019-R000440
 Clinical and immunological impact of Schistosoma mansoni infection and treatment on the course of chronic hepatitis B virus (HBV) infection in HIVuninfected patients in Uganda
REFNo: HS1002ES

To determine Clinical and immunological impact of Schistosoma mansoni (Sm) infection and treatment on the course of chronic hepatitis B virus (HBV) infection in Uganda. This will be done through the following aims: Aim 1: To define and quantify Sm infection, treatment response, and reinfection rates within a cohort of chronic HBV patients Aim 2: To determine the impact of Sm infection and treatment on HBV virological markers, disease stage, and longer-term progression among urban Ugandans Aim3: To determine if HBV-specific immunological responses in the periphery and within the liver are altered in response to Sm infection and treatment

Uganda 2021-01-27 2024-01-27 Medical and Health Sciences Non-degree Award
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