Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Enock Matovu
ID:
Development and Evaluation of Recombinant SARS-CoV-2 Spike and Membrane Protein-Based Sub-Unit Vaccines
REFNo: NS146ES

(i) To express recombinant subunits of the RBD region of the spike protein and the M protein
(ii) To characterize the humoral and cell mediated immune response generated by the RBD region and the M protein in mouse models
(iii) To determine the safety of the vaccine candidates in mouse models
(iv) To determine the efficacy of the potential candidate vaccine in mice

Uganda 2021-05-20 2024-05-20 Natural Sciences Non-degree Award
Lena Mpalampa
ID:
FACTORS ASSOCIATED WITH PROVISION OF PHYSICAL ACTIVITY IN PRIMARY SCHOOLS IN MAKINDYE DIVISION IN KAMPALA
REFNo: SS768ES

5. To establish the school related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,4. To establish the class related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,3. To ascertain the teacher related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,2. To describe the various types of physical activity offered in primary schools in Kampala during the school term,1. To determine the proportion of schools offering sufficient time for PA among primary schools in Kampala during the school term,To analyse the factors associated with insufficient physical activity offered in primary schools in Makindye Division in Kampala during the school term.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Degree Award
Katelin Wilton
ID:
Supporting Families through Community Health Workers during COVID: A feasibility and acceptability study
REFNo: SS752ES

Main objective/ purpose
The main objective of this study is to better understand coping strategies of frontline health workers, feasibility and acceptability indicators of messaging success.
Specific Objectives
The specific objectives of this study are to:
• Understand frontline health workers perspective on their stress and psychosocial wellbeing
• Understand the feasibility and acceptability of behaviorally-informed SEL and MHPSS messaging targeted at adult and child clients delivered through frontline health workers
• Determine whether such messaging targeted at clients may also improve frontline health worker coping strategies

USA 2021-05-20 2024-05-20 Social Science and Humanities Non-degree Award
Paul Atherton
ID:
Girls’ Education Challenge Phase II: Continued Access and Learning during Covid-19 in GEC-II PEAS treatment and control schools in Uganda
REFNo: SS764ES

The final research questions for the proposed study are listed below:

a) How have PEAS sought to provide continued access to learning opportunities during school closures?
b) How are the PEAS supporting girls to return to school, and with what effects on girls’ access to learning opportunities?
c) How are PEAS identifying which girls are most at risk of not returning to school? Can a scorecard approach help projects identify those most at risk within projects in a cost-effective way?
d) How have girls’ learning levels changed during the COVID-19 period?

UK 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINNIE NAMBATYA
ID:
Evaluation of the complexity of medicine regimens and drug therapy problems among children with sickle cell anemia in Jinja Regional Referral Hospital: A prescription audit
REFNo: HS1299ES

• To determine the complexity of medication regimens prescribed to the patients with SCA.
• To determine the incidence of DTPs among medications prescribed to children with SCA.

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
ALERT – ACTION LEVERAGING EVIDENCE TO REDUCE PERINATAL MORTALITY AND MORBIDITY IN SUB-SAHARAN AFRICA
REFNo: HS1324ES

To develop and evaluate a multifaceted intervention to i) strengthen the implementation of evidence-based interventions and responsive care and ii) reduce in-facility perinatal mortality and morbidity through a multidisciplinary approach in Benin, Malawi, Tanzania and Uganda.
Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
Mark Okwir
ID: UNCST-2021-R013417
Spectrum, Outcomes, and Factors Associated with the Liver disease in a Tertiary Care Hospital, Northern Uganda: a 5 Year Retrospective Study.
REFNo: HS1333ES

General Objectives
To determine the spectrum, outcome, and factors associated with liver disease in patients admitted at Lira hospital in northern Uganda over the last five years.

Specific Objectives:
1. To describe the spectrum of liver disease among patients admitted to Medical wards in Lira Regional Referral Hospital over the last five years.
2. To determine the factors associated with liver disease among patients admitted with liver disease at Lira Hospital in the last five years.
3. Determine the admission outcomes (mortality and survival) of liver diseases among patients admitted at Lira Reginal Referral Hospital in the last five years.
4. To determine the factors associated with the admission outcomes (mortality and survival) of patients admitted with liver disease at LRRH in the last five years.

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
SHAMIM NAMUKASA
ID:
Prevalence of Sickle Cell Trait and Needs Assessment for Up-Take of Sickle Cell Screening Among Secondary School Students in Kampala City
REFNo: SS818ES

To explore the stakeholders' perceptions regarding the uptake of sickle cell screening among secondary school students in Kampala City,To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,To determine the prevalence of sickle cell trait among secondary school students in Kampala City,Determine the prevalence of sickle cell trait among secondary school students and identify student-related and stakeholders' factors influencing up-take of sickle trait screening,3. To Explore the stakeholders' perspectives regarding the uptake of sickle cell screening services among secondary school students in Central Uganda.,2. To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,1. To determine the proportion of sickle cell among secondary school students in Central Uganda.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Lubega Biyinzika
ID: UNCST-2020-R014149
Perceptions and adherence to preventive measures for Coronavirus Disease 2019 among rural community households in Wakiso district, Uganda.
REFNo: SS819ES

3. To explore community barriers and facilitators of adherence to COVID-19 preventive measures among rural community households.,2. To assess adherence to COVID-19 preventive measures as issued by the Government of Uganda among rural community households.,1. To assess perceptions towards COVID-19 preventive measures among rural community households. ,To assess community perceptions and adherence to COVID-19 preventive measures in rural community households of Wakiso district, Uganda in order to provide essential information needed by public health officials and other stakeholders to make an informed decision on the most effective strategy for reduced community transmission.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
Prevalence of Polymorphic genes of Alzheimer disease in Nodding disease Tauopathy.
REFNo: HS726ES

To determine if polymorphisms in the eight common genes associated with Alzheimer Disease (APP, MAPT, PREN-1, PREN-2, BACE-1, BACE-2, IDE, and APOE-ε4) are present in DNA of Nodding Disease patients
Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
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