Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 6,466
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
David Katende
ID:
Characterization of New Childhood HIV Infections in USAID supported regions in Uganda (NCHiS)
REFNo: HS4857ES

The assessment aims to characterize those children newly diagnosed with HIV in terms of their demographics, geography, access to care, care continuum and social determinants, to inform child HIV services on targeted and effective case finding and treatment services that can support the reversal of sub-optimal case finding and viral load suppression, and the stagnation in the overall rate of new vertical infections.
a. Primary objective
To describe the determinants or associated risk factors of persisting vertical HIV infections among children.
b. Secondary objectives
i. To report on the perspectives of key stakeholders on the utilization of child HIV services from implementor to the recipient.
ii. To describe the distribution of HIV seropositive children by HIV acquisition mode e.g., vertical MTCT (PMTCT and non-PMTCT), BF, through sex, trauma/GBV.
iii. To establish the proportion of uniquely identified HIV seropositive children in the survey region.

 Uganda 2024-09-04 11:10:19 2027-09-04 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jafesi Pulle
ID: UNCST-2020-R014213
 Understanding the causes of deaths amongst persons with Rheumatic Heart Disease in Uganda
REFNo: HS4663ES

Main objective: To identify the causes of death among RHD registrants in the National RHD registry in Uganda
 Uganda 2024-09-02 15:12:28 2027-09-02 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Esther Babirekere Iriso
ID: UNCST-2024-R005372
 International Investigation into the Genetics of Severe Acute Malnutrition in Children
REFNo: HS4569ES

Determine the contributions of genetic markers to the development of ESAM vs NESAM and its clinical characteristics Elucidate the role of epigenetic mechanisms in the development of ESAM vs NESAM
 Uganda 2024-08-30 15:11:38 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Brenda Larison Jean
ID:
Investigating the Genetic Causes of Malformed Stripe Patterns in Plains Zebras
REFNo: NS831ES

Our primary objective is to understand the causes (specific genes, low heterozygosity) of abnormal striping in plains zebras

Specific Objectives:
1. Collect samples from both individuals with abnormal striping and normal striping in order to discover the genes associated with the various forms of abnormal striping

2. Use these same samples to further assess the potential relationship between aberrant striping and genomic heterozygosity
 USA 2024-08-30 15:05:53 2027-08-30 Natural Sciences Non-Clinical Trial Non-degree Award
Barnabas Bakamutumaho
ID: UNCST-2021-R012636
 MULTIDIMENSIONAL AND LONGITUDINAL IMMUNE PROFILING OF SEPSIS IN UGANDA
REFNo: HS4546ES

General Objective:
The overall goal of this project is to stratify sepsis patients in Uganda into biologically driven and therapeutically relevant subtypes.
Specific Aims/Objectives:
(1) Establish pathobiologically-driven and clinically meaningful sepsis endotypes in Uganda
(2) Define longitudinal immune response trajectories associated with sepsis-related death and disability
(3) Determine immune cell phenotypes and function unique to sepsis in persons living with HIV (PLWH).

Uganda 2024-08-30 15:04:57 2027-08-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."

NRIMS