Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Esther Buregyeya
ID: UNCST-2020-R014116
USING SHORT MESSAGE SERVICE REMINDERS AND MOBILE MONEY INCENTIVES TO ENHANCE LINKAGE TO CARE OF PRESUMPTIVE TUBERCULOSIS PATIENTS IN UGANDA: A RANDOMISED CONTROLLED TRIAL
REFNo: HS993ES

To evaluate the TB diagnostic process and linkage to care by doing cohort analysis.

2. Develop and adapt an SMS reminders and MM incentives to improve linkage to care among TB patients.

3. Conduct a randomized controlled trial of SMS reminders and MM incentives sent to presumptive and confirmed TB patients to improve linkage to care and treatment.

4. To build sustainable capacity in TB research clinical trials in Uganda.

Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Jude Onyango Tadeo
ID:
FAMILY SUPPORT, DIABETES SELF-MANAGEMENT, AND GLYCEMIC CONTROL AMONG PATIENTS ATTENDING DIABETIC CLINICS OF REGIONAL REFERRAL HOSPITALS IN EASTERN UGANDA (FS-DSM-GC STUDY)
REFNo: HS1040ES

Research Study objectives:
General objective:
To examine the association between perceived family support, diabetes self-management behavior and glycemic control among patients attending Regional Referral hospitals in the eastern region of Uganda.
Specific objectives:
1. To determine the association between perceived family support and diabetes self-management behavior among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.
2. To determine association between perceived family support and glycemic control among patients attending outpatient clinics of Regional Referral Hospitals in the eastern region of Uganda.

Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Jonathan Mayito
ID:
Utility of the monocyte to lymphocyte ratio in diagnosing latent tuberculosis among HIV-infected individuals with a negative tuberculosis symptom screen.
REFNo: HS1066ES

1. To determine the diagnostic performance of the monocyte to lymphocyte ratio against IGRA in diagnosing latent TB among HIV-infected individuals with a negative tuberculosis symptom screen.
2. To determine the change in the monocytes to lymphocytes ratio measured at baseline, and three months among HIV-infected individuals during tuberculosis preventive therapy.

Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Namulema Edith
ID:
Evaluation of the Safety and Tolerability of the ‘LeVe CPAP Flow Generator’ in Healthy Volunteers at Mengo Hospital in Kampala Uganda
REFNo: HS1250ES

To determine the safety, tolerability and acceptability of the LeVe CPAP Flow Generator’ among healthy volunteers at Mengo Hospital and to ensure they do not cause harm.
Uganda 2021-03-05 2024-03-05 Medical and Health Sciences Non-degree Award
Patrice Mawa Akusa
ID:
Establishing a pool of school-going adolescent girls and boys as immunisation ambassadors in Entebbe, Uganda
REFNo: HS1215ES

Overall rationale One way of engaging and empowering mothers and communities and linking them to immunisation services is by use of their own daughters and sons. The relationship between mother and her daughter is full of learning experiences and one of the strongest bonds. Mothers also have emotional relationship with their sons and will likely listen to them. Objectives The objective of the project is to establish a pool of school-going adolescent girls and boys as‘immunisation ambassadors’ and change agents able to engage and empower mothers and community members and link them to maternal and neonatal immunisation services by training them on vaccines and leadership skills.
Uganda 2021-03-03 2024-03-03 Medical and Health Sciences Non-degree Award
Sylvia Nabukenya
ID: UNCST-2019-R000906
UNDERSTANDING STAKEHOLDER PERSPECTIVES, PREFERENCES AND EXPERIENCES FOR THE RETURN OF PHARMACOGENOMICS RESEARCH RESULTS AMONG PEOPLE LIVING WITH HIV AIDS.
REFNo: SS735ES

GENERAL OBJECTIVE

To explore stakeholder perspectives, preferences and experiences in contribution to development of locally contextualized institutional guidelines for returning individual pharmacogenomics research results to people living with HIV.

SPECIFIC OBJECTIVES

1. To explore stakeholders’ attitudes, perspectives and experiences towards the return of individual pharmacogenomics research results among people living with HIV.

2. To determine factors that influence decisional preferences for receiving individual pharmacogenomics research results among people living with HIV

3. To develop institutional guidelines for the return of individual pharmacogenomics research results to research participants.

Uganda 2021-03-03 2024-03-03 Social Science and Humanities Degree Award
Patrice Mawa Akusa
ID:
Exploring immune responses in primary and more advanced Schistosoma mansoni infection and treatment of preschool-age children using Aurora spectral flow cytometry
REFNo: HS1223ES

Objective 1: To characterize immune responses of PSAC in primary and more advanced S. mansoni infection

Objective 2: To determine the effect of PZQ treatment of S. mansoni on immune responses in PSAC.

Uganda 2021-03-03 2024-03-03 Medical and Health Sciences Non-degree Award
LYDIA NAKIGANDA JACENTA
ID:
Demographic characteristics, attitudes, behaviours and sexually transmitted infections among female sex workers using HIV Pre- Exposure Prophylaxis living in the fishing communities around Lake Victoria Basin, Uganda.
REFNo: HS813ES

i.To define demographic characteristics
ii.To explore sexual behaviours, in association with PrEP prescription,
iii. To explore self-reported adherence rates and correlates of adherence
iv. To examine the STI disease burden, use of condoms and explore associations between condom use and STIs.
v. To explore factors that might facilitate or challenge PrEP use, such as side effects and stigma, and
vi. To understand FSWs’ experiences, perceptions of & attitudes towards PrEP

Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Degree Award
Jaffer Okiring
ID:
Increasing malaria trends amidst routine core interventions among residents of varying transmission settings of Uganda
REFNo: HS1033ES

1) To compare the malaria trends measured using Test Positivity Rate and Total laboratory confirmed cases of malaria relative to incidence in high malaria settings in Uganda
2) To determine household level factors associated with malaria incidence at 68 sites with varying malaria transmission intensity.
3) To investigate the environmental factors associated with malaria incidence and how these factors modify the impact of core vector control interventions in Uganda
4) To develop a model that can predict malaria incidence in different epidemiological settings and how the incidence will vary with the roll out of different core interventions in Uganda.

Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Degree Award
Elizeus Rutebemberwa
ID: UNCST-2022-R009070
Evaluation and Scale-up Strategy for the Doctor@Distance Programme in Uganda
REFNo: HS955ES

4.3 General objective
To evaluate the Doctor@Distance programme by identifying current benefits and gaps and exploring the path for further development of the programme and potential embedment of the programme in the larger health system.

4.4 Specific objectives
1.To explore what the multi-stakeholder perceptions are on the design and daily practice of the Doctor@Distance programme
2.To analyse the design and current utilisation of the Doctor@Distance programme and identify potential gaps in its coverage (how often is it used, by whom, for which diseases, etc.)
3.To evaluate the current healthcare gaps in the communities in which the community health entrepreneurs of the Doctor@Distance programme are active
4.To explore how the Doctor@Distance programme can be scaled-up to other districts within Uganda
5.To investigate multi-stakeholder perceptions on the possibility of integration of the Doctor@Distance programme in the larger health system in Uganda


Uganda 2021-03-01 2024-03-01 Medical and Health Sciences Non-degree Award
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