Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
Assessing the reliability and test performance of malaria rapid diagnostic tests after expiration.
REFNo: HS4760ES

AIM 1: Estimate the reliability, defined as the proportion of malaria RDTs that function (i.e., appearance of control band) at various time-points up to one year after expiration. AIM 2: Determine the test performance (e.g., sensitivity, specificity) of malaria RDTs for the diagnosis of P. falciparum malaria at various time-points up to one year after expiration compared to non-expired RDTs and routine light microscopy performed in parallel. AIM 3: Estimate the time-to-negativity after treatment among participants with a positive RDT on enrollment.,The primary objective of the proposed project is to evaluate the performance of malaria RDTs at various states of expiration (e.g., 1-, 2-, 3-months post-expiration) compared to non-expired RDTs in routine use. If our hypothesis is correct, our results may facilitate (i) use beyond the stated expiration and/or production of RDTs with longer expiration periods, both of which could reduce medical waste. ,
Uganda 2024-09-10 11:02:24 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
MICHAEL KAWOOYA GRACE
ID: UNCST-2020-R014672
The African Breast Imaging Dataset for Equitable Cancer Care (The ABreast Data set)
REFNo: HS4709ES

1. To train community health workers to conduct breast examination using hand held ultrasound machines in the community
2. To develop the first publicly available expert-labelled ultrasound imaging data with mammograms, a wealth of clinical profiles, and where available biopsy pathology data.
3. Introduce the Abreast Challenge, as a new image segmentation grand challengevii at the 2024 Medical Image Computing and Computer Assisted Intervention Society (MICCAI) annual meeting, happening for the first time in Africa (Morocco).
4. Introduce a baseline state of the art (SOTA) model of a deep learning approach for lesion detection of breast lesions on low-cost (also low-resolution) POC-US for wider screening accessibility.
5. Train up to 70 African clinicians and researchers to develop SOTA ML lesion detection methods to ensure that SSA retains a local community of skilled experts who are knowledgeable on how to use ML data to solve local health needs.
Uganda 2024-09-10 10:56:03 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick Kagurusi Tumusiime
ID: UNCST-2021-R012687
Evaluating the Impact of DESC Approach: Comparative Quasi-Experimental Study of Community Health Worker Performance in Moyo and Adjumani Districts, West Nile Uganda
REFNo: HS4756ES

1) To evaluate the impact of the DESC Approach on CHW performance metrics, including CHW reporting rates, household visits, health services provided, and engagement in activities.
2) To generate evidence on performance-based pay options to inform policies on CHW compensation at the district level by October 2024
3) To compare CHW performance between intervention (Moyo District) and non-intervention (Adjumani District) areas.
4) To assess the effectiveness of mobile technology utilization, training, and performance-based incentives in enhancing CHW performance.
Uganda 2024-09-10 10:52:55 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JUDITH AWACORACH
ID: UNCST-2024-R004547
GREEN FINANCE INCENTIVES AND SUSTAINABLE LIVELIHOOD OUTCOMES IN UGANDA
REFNo: SS2993ES

To examine the mediating role of competitive advantage of green charcoal value chain in the relationship between Green Finance incentives and sustainable Livelihood outcomes in Uganda,To examine the mediating roles of green charcoal value chain in the relationship between Green Finance incentives and sustainable livelihood outcomes of green charcoal production in Uganda.,To examine the competitiveness of green finance incentive for green charcoal in sustainable livelihood outcomes in Uganda,To assess the contributions of green finance incentives in the green charcoal value chain to enhance sustainable livelihood outcomes in Uganda.,To assess the green finance use in green charcoal production to enhance sustainable livelihood outcomes in Uganda,To assess availability and accessibility of green finance incentives and its contributions to sustainable livelihood outcomes in Uganda,
Uganda 2024-09-10 10:49:52 2027-09-10 Social Science and Humanities Non-Clinical Trial Degree Award
Alison Elliott
ID: UNCST-2023-R006524
OBTAINING SINGLE-CELL LEVEL INSIGHTS INTO THE IMMUNOLOGICAL AND METABOLIC PATHWAYS ASSOCIATED WITH VACCINE HYPO-RESPONSIVENESS [REVERSE]
REFNo: HS4782ES

1. To measure the SARS-CoV-2 antibody response at baseline, 3 months after prime vaccination and 1 month after boost vaccination in European and Ugandan adults. 2. To characterise peripheral blood mononuclear cells (PBMCs) and their response to prime/booster vaccination with the AstraZeneca ChadOx1 nCoV-19 vaccine in European and Ugandan adults using single-cell technologies
UK 2024-09-10 10:45:15 2027-09-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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