Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Maureen Ayikoru
ID:
REVISED PROPOSAL IN RESPONSE TO THE OUTCOME OF ROUND 1 OF COMMITTEE REVIEW OF THE PROJECT “INDIRECT IMPACTS OF COVID-19 ON HEALTHCARE SYSTEMS: A CASE STUDY OF UGANDA’S HEALTHCARE PROFESSIONALS”
REFNo: HS1524ES

To document what lessons can be learnt from Uganda’s response to COVID-19,To analyse the impact of information and communication technologies and the media, including digital, print and broadcast media in containing the COVID-19 pandemic in Uganda.,To analyse what if any, political economy factors influence misinformation, resource reallocation and prioritisation during the ongoing pandemic and to document the perceived effects on the entire healthcare system including those most vulnerable,To identify what threats COVID-19 has had on physical, psychosocial, and overall well being of HCPs and to assess what if any formal and informal coping mechanisms have so far been available to them,To generate empirical evidence on the indirect impacts of Uganda’s response to COVID-19, focusing on the healthcare professionals.,
 Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
 Efficacy and safety of artemether-lumefantrine, pyronaridine-artesunate, artesunate-amodiaquine and dihydroartemisinin – piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda.
REFNo: HS1363ES

The general objective of this study is to assess the therapeutic efficacy and safety of artemether-lumefantrine (AL), pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP) for the treatment of uncomplicated P. falciparum malaria in three sentinel sites in Uganda.
The primary objectives are:
• to measure the clinical and parasitological efficacy of 4 artemisinin-based combination therapies (ACT), artemether-lumefantrine (AL) Pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP).
• to differentiate recrudescence from new infection of Plasmodium falciparum by molecular techniques.
The secondary objectives are:
• to evaluate the incidence of adverse events; and
• to determine the polymorphism of molecular markers mediating resistance for Artemsinin, Pyronaridine, Piperaquine and Lumefantrine resistance.
• to determine the blood concentration of Lumefantrine after treatment with Artemether- Lumefantrine .


 Uganda 2021-07-08 2024-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aubryn Sidle Allyn
ID:
Emplacing Agency in Girls' Education Practice: An Evaluation of Impact
REFNo: SS651ES

1. To evaluate the impact of CDOs’ programs on girls' Agency outcomes.
2. To understand how and why programs influence agency in adolescent girls, and what aspects of program design impede or speed this development.
3. To understand the relationship between girls’ agency and educational outcomes.
4. To evaluate the relationship between girls’ agency and teenage pregnancy incidence and determine what effect, if any, increased agency has on teenage pregnancy.
 USA 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Angelique Murorunkwere
ID:
DIAGNOSTIC DELAY AND ITS CAUSES AMONG PEDIATRIC CANCER PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL CANCER UNIT
REFNo: SS857ES

1. To determine the average time between onset
of symptoms and diagnosis among children
with cancer at MRRH
2. To outline caregiver self-reported reasons
for delayed diagnosis among children with
cancer at MRRH
3. To establish the correlates of delayed
diagnosis among children with cancer at
MRRH

 Rwanda 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Roseline Katusiime
ID:
Detecting and analysing micronutrient gaps in dietary patterns in Western Uganda: A comparison of different methods
REFNo: A122ES

1. To compare the 24-hour recall method with direct observation and weighing of food portions, so as to generate knowledge on their accuracy and make expert recommendations by the end of 2021.
2. To use the CIMI to identify nutrient deficiencies in particular gaps of Vitamin A, Zinc and Iron and generate CIMI based recommendations and suggestions on improved diets for the research participants at the end of June 2021.
3. To calculate the costs of improved diets and develop recommendations on affordable nutrient adequate diets for study participants by the end of 2021
4. To assess the advantages and disadvantages of different strategies used by development organizations in western Uganda in encouraging communities to embrace affordable nutrient adequate diets and feeding practices by June 2021

Uganda 2021-07-07 2024-07-07 Agricultural Sciences Degree Award
Deborah  Ojiambo
ID:
Efficacy of Group Activity Adherence Counselling (GAAC) for Adolescents with Unsuppressed HIV viral load at three large HIV clinics in Uganda: Randomized controlled trial
REFNo: SS805ES

1.To examine the barriers such as behavior problems and mental health problems to adherence experienced by adolescents living with HIV.
2.To evaluate the efficacy of GAAC in addressing barriers to adherence among adolescents living with HIV.

3.To assess whether GAAC is associated with viral load suppression, among adolescents living with HIV compared to Standard Service Provision (SSP)
 Uganda 2021-07-07 2024-07-07 Social Science and Humanities Clinical Trial Non-degree Award
Omony Geoffrey
ID:
Safeguarding the war-affected community in Gulu district in Northern Uganda
REFNo: SS830ES

1) To explore and document the impact of research and projects on former child soldiers, both the benefits and the harms, and capture how future projects which focus on the war-affected community can benefit them and what they require for their empowerment
2) to contribute new evidence on the impacts, both direct and indirect, of COVID-19, on persons with disabilities, led by persons with disabilities, with a focus on war-related disabilities in Northern Uganda. This evidence and data will include solutions for disability-inclusive pandemic recovery informed by persons with disabilities
3) to contribute towards the evidence and literature on safeguarding war-affected and post-conflict communities, and create outputs which are accessible to various audiences, including policymakers, academics, journalists, NGOs, and general public
4) to build the esteem of ex-child soldiers, persons with disabilities, and other war-affected groups in Northern Uganda, through involving them in participatory-action research, the design of outputs, and dissemination activities to foster confidence-building, inclusion, and empowerment
Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Georgina Pearson
ID:
Living the Everyday: Health-seeking in times of sickness and epidemics at Uganda’s borders
REFNo: SS878ES

1. To document everyday knowledge production on illness, among academics, media, public health practitioners and people living on and across border regions. 2. To identify patterns and practices of health-seeking across the border region., 3. To explore interactions between bodies of knowledge produced by various groups at the border, and detail convergences and divergences., 4. The above objectives will lead on to inform policies in response to potential and emergent threats in border regions.
 UK 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Degree Award
Gertrude Kiwanuka
ID:
ETHICAL ISSUES IN RECRUITMENT AND CONDUCTING RESEARCH DURING OUTBREAKS IN RESOURCE LIMITED SETTING
REFNo: SS883ES

1. To determine community voluntariness, understanding and preparedness to participate in research during life threatening infectious disease outbreaks.
2. To explore the perceptions of investigators and policy makers regarding the conduct of research during outbreaks of life threatening diseases in a resource limited setting. Investigators and policy makers play a critical role in setting and driving the research agenda.
3. To examine the ethical issues raised by members of research ethics committees regarding enrollment of participants in research during epidemic situations and the application of alternative designs.
4. To develop a short course on ‘‘Ethical issues in research during epidemics in a resource limited setting”. This will be based on findings from community, investigators and policy maker interactions and extensive review of the literature.

Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Annet Khaoya Irene
ID:
Women (in VSLA) Respond
REFNo: SS847ES

The study will be guided by the following key objectives which will also inform the key assessment questions during the survey • To assess how VSLAs (as collectives) and VSLA members are being affected by and coping with the pandemic • To assess the role VSLAs (as collectives) are playing in local response, including not only financial but also social (including health) and political roles • What action and support VSLAs need or want to see from other stakeholders including local and national authorities
Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
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