Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Elizabeth Ayebare Ombeva
ID: UNCST-2020-R003666
 Experiences of the CEI members and Researchers working together during Global Health Research on Stillbirth Prevention and Bereavement Care: A grounded theory study in Sub-Saharan Africa and South Asia.
REFNo: SS4036ES

To produce an explanatory theory to underpin a working framework to support relevant research projects and programmes,To understand social processes that guide relationships between CEI members and researchers within a large global health programme,To understand researchers’ experiences of engaging with the CEI group within a large global health programme,To understand CEI group member experiences of contributing to research within a large global health programme,To gain better understanding of facilitators and barriers to effective community engagement through a grounded theory approach,
 Uganda 2025-08-18 13:51:30 2028-08-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
Joseph Ekong
ID: UNCST-2025-R017564
 Why did they get infected? Audit of MTCT risk factors among HIV-positive Infants attending Faith Based Health facilities in Uganda.
REFNo: HS5987ES

3. To identify Maternal and HIV positive Infant risk factors associated with MTCT of HIV among infants diagnosed as HIV-positive attending faith-based health facilities in Uganda. ,2. To assess the effectiveness and coverage of maternal adherence to antiretroviral therapy (ART) and infant prophylaxis by attending faith-based health facilities in Uganda.,1. To determine the socio-demographic characteristics of Mothers and HIV-positive Infants attending Faith Based Health Facilities in Uganda.,This study aims to determine the risk factors contributing to mother-to-child transmission (MTCT) of HIV among HIV-positive infants attending Faith-Based Health Facilities in Uganda, to inform targeted Ministry of Health of Uganda interventions to prevent future cases in Faith-based Health facilities.,
 Uganda 2025-08-18 13:42:26 2028-08-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Barbara Amanya Lynn
ID: UNCST-2024-R016287
 Work-Life Balance Practices, Psychological Well-being, and Employee Engagement Among Academic Staff at Uganda’s Private Universities
REFNo: SS4119ES

i. To determine the association between flexible work arrangements and employee engagement of academic staff among private universities in Uganda. ii. To investigate the relationship between leave programmes and employee engagement of academic staff among private universities in Uganda. iii. To examine the impact of wellness programmes on employee engagement of academic staff among private universities in Uganda. iv. To analyze the mediating effect of psychological well-being on the relationship between work-life balance practices and employee engagement of academic staff among private universities in Uganda.
Uganda 2025-08-18 13:38:10 2028-08-18 Social Science and Humanities Non-Clinical Trial Degree Award
MOSES ISANGA
ID: UNCST-2025-R018239
 MULTIFACETED INTERVENTIONS AND HIV RISKY SEXUAL BEHAVIORS AMONG ADOLESCENT GIRLS AND YOUNG WOMEN: A CASE STUDY OF THE DREAMS PARTNERSHIP IN MUBENDE REGION, UGANDA
REFNo: HS6319ES

1. To determine the prevalence of risky sexual behaviors (RSB) among adolescent girls and young women (AGYW). 2. To assess the reach of multifaceted interventions among adolescent girls and young women (AGYW). 3.To investigate the influence of multifaceted interventions on risky sexual behaviours among adolescent girls and young women (AGYW) 4. To identify and synthesize barriers and facilitators to multifaceted interventions for reducing risky sexual behaviors among adolescent girls and young women (AGYW).
 Uganda 2025-08-18 13:36:40 2028-08-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Joeri Smits
ID: UNCST-2025-R018883
 Search frictions in credit markets
REFNo: SS4207ES

To assess the feasibility of evaluating whether a digital loan comparison tool—providing tailored information on loan cost and predicted approval likelihood—can help prospective borrowers make better-informed application decisions in Uganda’s credit market.
Netherlands 2025-08-18 13:30:49 2028-08-18 Social Science and Humanities Non-Clinical Trial Non-degree Award
RACHEL LUWAGA
ID: UNCST-2024-R003040
 EFFECT OF A DISCHARGE EDUCATION INTERVENTION ON PREVENTION OF PUERPERAL SEPSIS AMONG MOTHERS WHO HAVE DELIVERED BY CESAREAN SECTION IN SOUTHWESTERN UGANDA
REFNo: HS5504ES

. To determine the prevalence, factors, and outcomes associated with readmission of
mothers who had undergone cesarean section delivery due to sepsis in Mbarara Regional
Referral Hospital
2. To describe the experiences and practices of mothers in the prevention of puerperal sepsis
post cesarean section in Mbarara Regional Referral Hospital
3. To explore the barriers and facilitators to the provision of discharge instructions
regarding puerperal sepsis prevention for mothers who have delivered by cesarean
section in Mbarara Regional Referral Hospital
4. To determine the effect of a discharge education intervention in the prevention of puerperal of
sepsis in post-cesarean section mothers.

Uganda 2025-08-18 13:28:40 2028-08-18 Medical and Health Sciences Clinical Trial Degree Award
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
 Determining the Risk of Rheumatic Heart Disease Following Prophylaxis Discontinuation (GOAL-Keep)
REFNo: HS6310ES

Aim 1: Determine the risk of developing moderate/severe rheumatic heart disease (RHD) up to 3 years after Secondary antibiotic propylaxis (SAP) discontinuation among children and adolescents with mild RHD, who have shown echocardiographic stability for at least 2 years on SAP.
Aim 2: Determine the risk of developing moderate/severe RHD up to 6 years after SAP discontinuation among children and adolescents originally with mild RHD, who have shown echocardiographic normalization.

Uganda 2025-08-18 13:25:57 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Dickens Akena Howard
ID: UNCST-2019-R000179
 Cultural adaptation of the coordinated specialty care (NAVIGATE) in Uganda
REFNo: HS6280ES

Study objective: The study objectives will include

Objective 1. Culturally adapting and locally contextualizing NAVIGATE into a CSC manual (NAVIGATE-UG) for use in Uganda.

Objective 2: Documenting the feasibility and acceptability of using the adapted NAVIGATE-UG manual

Uganda 2025-08-18 13:24:11 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Moses Sainge Nsanyi
ID: UNCST-2025-R019399
 Cloud immersion and the future of tropical montane forests (CLOUDFOR)
REFNo: NS991ES

This project aims to quantify water input, tree growth and future species distribution models in the Bwindi Impenetrable Forest National Park, Uganda with three main objectives:
1) To determine the importance of cloud immersion for maintaining annual water inputs and tree growth,
2) To quantify the consequences of future changes in cloud immersion for carbon stocks and fluxes,
3) To assess how different dominant tree species respond to changes in cloud immersion.

 Cameroon 2025-08-18 13:22:39 2028-08-18 Natural Sciences Non-Clinical Trial Non-degree Award
PATRICIA NAKASI
ID: UNCST-2022-R009767
 Prevalence, Symptoms and Baseline characteristics across Menopausal Stages in Women Living with HIV: A cross-sectional study in Uganda.
REFNo: HS6289ES

Objective 1: To describe the prevalence of premenopause, perimenopause and postmenopause among WLHIV aged 35-60years Objective 2: To describe the menopause symptoms experienced by WLHIV Objective 3: To compare the baseline characteristics across menopausal stages in WLHIV
 Uganda 2025-08-18 13:20:32 2028-08-18 Medical and Health Sciences Non-Clinical Trial Degree Award
Semitala Fred
ID: UNCST-2020-R014202
 3HP Self-Administered Therapy Strategy, Cluster Randomized Trial (Year 1):Formative Research Study
REFNo: HS6228ES

Aim 1: To collect data on site and patient characteristics to inform stratified randomization with restriction.
Aim 2: To collect patient-level, routinely collected demographic, clinical, and outcome data from clinic registers to establish baseline 3HP initiation and completion rates.

 Uganda 2025-08-18 13:19:26 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Phionah  Ssemambo Kibalama
ID: UNCST-2025-R018119
 COMPASS: Community Perspectives and Behavior Change Strategies for Integrated Long-Acting Reversible Contraception and Long-Acting Injectable PrEP Roll Out for Adolescent Girls and Young Women in Uganda
REFNo: HS6232ES

The overall objective of this study is to enhance the adoption and utilization of integrated LARC and LAI-PrEP services among AGYW in Uganda by understanding their preferences, willingness to use these services, and the influencing perceptions, practices, and norms of key stakeholders.

Primary objectives:
1. Determine preferences and willingness to use LARC and LAI-PrEP by AGYW in Uganda.
2. Characterize stakeholder perceptions, practices, and norms that may influence the adoption of integrated LARC and LAI-PrEP services for AGYW, using the Capability, Opportunity, and Motivation-Behavior (COM-B) model to identify facilitators and barriers, alongside the Behavior Change Wheel (BCW) to develop targeted behavior change strategies.

Uganda 2025-08-18 13:06:49 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Kazibwe Herman
ID: UNCST-2025-R017099
 IDENTIFICATION OF MINIMAL DATA ELEMENTS FOR PHYSIOTHERAPY OF TRAUMATIC BRAIN INJURY PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL AND MULAGO NATIONAL REFERRAL HOSPITAL
REFNo: HS6201ES

Research Question: What minimal data elements related to physiotherapy are acceptable and feasible for addition into a TBI database maintained at national & regional hospitals in Uganda? Objectives 1.To identify the minimal rehabilitation data elements, informed by international TBI databases, that are appropriate to propose for addition to the current TBI database at two Ugandan hospitals: Mulago National Referral Hospital(MNRH), and Mbarara Regional Referral Hospital (MRRH). 2.To retrospectively assess data quality in medical documentation for each element at MNRH and MRRH. 3.To identify user perspectives of barriers and facilitators to consistent data collection of the identified and proposed data elements across both MNRH and MRRH.
Uganda 2025-08-18 13:05:10 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Robert Mutumba
ID: UNCST-2025-R019247
 CHARACTERIZATION OF INCONCLUSIVE SAMPLES ACCORDING TO RAPID TEST FOR RECENT INFECTION (RTRI) IN UGANDA
REFNo: HS6130ES

Main objective of the study is to determine the status of inconclusive samples tested in the field for HIV-1 recent infection.
Specific objectives
1.To perform additional characterization on field tested samples where RTRI results are discrepant with the national HIV testing algorithm (i.e., RTRI “Inconclusive”) to understand patterns or reasons for discrepant results.
2.To identify potential sources of testing errors to help improve quality of recency testing.
3.To compare Asante field tested results with results of the national HIV testing algorithm for RTRI Inconclusive samples

 Uganda 2025-08-18 12:55:05 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
WINFRED NANNOZI
ID: UNCST-2024-R004301
 PREVALENCE AND FACTORS ASSOCIATED WITH TOMOPHOBIA AMONG PRE-OPERATIVE PATIENTS AT KYABIRYA SURGICAL CENTER, BUDONDO SUB-COUNTY, JINJA CITY
REFNo: HS5857ES

To establish the institutional predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To assess the patient-related predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To determine the prevalence of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,To assess the predictors of tomophobia among pre-operative patients at Kyabirya surgical center, Budondo sub-county, Jinja city,
 Uganda 2025-08-18 12:53:37 2028-08-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ALPHONSINA MUJAWIMANA
ID: UNCST-2024-R015924
 PREVALENCE, PATTERNS AND FACTORS ASSOCIATED WITH NEURODEVELOPMENTAL DELAY AMONG YOUNG CHILDREN ATTENDING THE PAEDIATRIC OUT PATIENT DEPARTMENT CLINIC AT MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS6113ES

General Objective To determine the prevalence, patterns, and factors associated with Neurodevelopmental Delay among young children attending the Paediatric OPD Clinic at Mbarara Regional Referral Hospital Specific objective 1.To determine the prevalence of neurodevelopmental delay among children under five years at the paediatric OPD at MRRH. 2.To describe the patterns of neurodevelopmental delay among children under five years at the paediatric OPD at MRRH. 3.To assess the factors associated with neurodevelopmental delay among children under five years at the paediatric OPD at MRRH
Uganda 2025-08-08 16:28:48 2028-08-08 Medical and Health Sciences Non-Clinical Trial Degree Award
Edirisa Kibuuka
ID: UNCST-2025-R016973
 Improving care and support of children with Cerebral palsy: Feasibility and Acceptability of Family care-group model in Kawempe division, Uganda
REFNo: HS6115ES

To evaluate coverage, appropriateness, adoption, acceptability, feasibility, fidelity and costs of implementing CP-family care-group model in improving supportive care of children with CP in peri-urban communities of Kawempe division,To assess perceived barriers and facilitators to implementing CP-family care-group model in improving care and support of children with CP at community, facility and division. ,We intend to roll-out cerebral palsy family care-group model in selected health facility catchment areas to reduce stigma/discrimination and improve supportive care of CP children in Kawempe division,
 Uganda 2025-08-08 16:27:42 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Victor Lomonyang
ID: UNCST-2025-R017018
 Prevalence of perceived stigma and associated factors among patients with tuberculosis (TB). A cross-sectional study in Napak district, Karamoja region, Uganda.
REFNo: HS6105ES

Overall Objective: To determine the prevalence of perceived stigma and associated factors among patients with tuberculosis in Napak district, Karamoja region, Uganda. Specific Objective 1: To determine the prevalence of perceived stigma among patients with tuberculosis in Napak District. Specific Objective 2: To identify the factors associated with perceived TB stigma among patients with tuberculosis in Napak District.
Uganda 2025-08-08 16:26:22 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ESTHER NANSAMBA
ID: UNCST-2024-R002776
 SUCCESSION PLANNING PRACTICES, ORGANIZATIONAL CULTURE AND SURVIVABILITY OF HOTELS IN WESTERN UGANDA
REFNo: SS3479ES

i.To examine the effect of skill development on hotel survivability in western Uganda.
ii.To determine the effect of mentorship on hotel survivability
iii.To establish the effect of internal promotion on hotel survivability in western Uganda
iv.To determine the moderating effect of organizational culture on the relationship between succession planning practices and the survivability of hotels in western Uganda.
v.To determine the level of survivability of hotels in western Uganda.
 Uganda 2025-08-08 16:24:31 2028-08-08 Social Science and Humanities Non-Clinical Trial Degree Award
Edgar Mulogo Mugema
ID: UNCST-2023-R008170
 Evaluation of a point-of-care molecular diagnostic test for brucellosis
REFNo: HS6127ES

Aim 1. Evaluate a point-of-care, rapid recombinase polymerase amplification, lateral flow detection assay (RPA-LF) for Brucella using clinical specimens from children and adults in rural southwestern Uganda with suspected brucellosis. Aim 1a: Determine the sensitivity, specificity, positive predictive value, and negative predictive value of the RPA-LF assay as compared to the current gold standard, blood culture, and quantitative PCR (qPCR). At Epicentre Uganda Research Laboratory, we will retrospectively perform the RPA-LF test on blood collected from patients presenting to health facilities in the Kazo and Kasese districts with malaria-negative fever for 1 week and one or more of the following symptoms: night sweats, headache, weight loss, fatigue, myalgia or arthralgia, and anorexia. We hypothesize that the RPA-LF assay can be successfully conducted in Uganda in a reference laboratory setting. In addition, we postulate that its sensitivity will be better than that of the currently available qualitative slide agglutination test and blood culture and will match that of qPCR. Aim 2b: Demonstrate the preliminary feasibility of RPA-LF test use at a peripheral health center in rural southwestern Uganda. We will conduct a small pilot sub-study to assess the acceptability and feasibility of test implementation by laboratory technicians at one of the study sites. We hypothesize that the assay can be successfully performed by local laboratory staff with minimal capacity investment. Aim 2: Explore the use of the RPA-LF assay for testing of cow and goat milk. For participants who test positive for brucellosis by slide agglutination test or blood culture, we will test self-collected pooled milk samples from their households using the Brucella Milk Ring Test and the RPA-LF assay and assess concordance between the two diagnostic methods.,The objective of this proposal is to preliminarily validate an RPA-LF assay for brucellosis that can be implemented in rural contexts in LMIC to improve brucellosis diagnosis and management.,
 Uganda 2025-08-08 16:22:39 2028-08-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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