Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Paul Atherton
ID:
Girls’ Education Challenge Phase II: Continued Access and Learning during Covid-19 in GEC-II PEAS treatment and control schools in Uganda
REFNo: SS764ES

The final research questions for the proposed study are listed below:

a) How have PEAS sought to provide continued access to learning opportunities during school closures?
b) How are the PEAS supporting girls to return to school, and with what effects on girls’ access to learning opportunities?
c) How are PEAS identifying which girls are most at risk of not returning to school? Can a scorecard approach help projects identify those most at risk within projects in a cost-effective way?
d) How have girls’ learning levels changed during the COVID-19 period?

UK 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
WINNIE NAMBATYA
ID:
Evaluation of the complexity of medicine regimens and drug therapy problems among children with sickle cell anemia in Jinja Regional Referral Hospital: A prescription audit
REFNo: HS1299ES

• To determine the complexity of medication regimens prescribed to the patients with SCA.
• To determine the incidence of DTPs among medications prescribed to children with SCA.

 Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Waiswa Peter
ID: UNCST-2020-R014921
 ALERT – ACTION LEVERAGING EVIDENCE TO REDUCE PERINATAL MORTALITY AND MORBIDITY IN SUB-SAHARAN AFRICA
REFNo: HS1324ES

To develop and evaluate a multifaceted intervention to i) strengthen the implementation of evidence-based interventions and responsive care and ii) reduce in-facility perinatal mortality and morbidity through a multidisciplinary approach in Benin, Malawi, Tanzania and Uganda.
 Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
Mark Okwir
ID: UNCST-2021-R013417
 Spectrum, Outcomes, and Factors Associated with the Liver disease in a Tertiary Care Hospital, Northern Uganda: a 5 Year Retrospective Study.
REFNo: HS1333ES

General Objectives
To determine the spectrum, outcome, and factors associated with liver disease in patients admitted at Lira hospital in northern Uganda over the last five years.

Specific Objectives:
1. To describe the spectrum of liver disease among patients admitted to Medical wards in Lira Regional Referral Hospital over the last five years.
2. To determine the factors associated with liver disease among patients admitted with liver disease at Lira Hospital in the last five years.
3. Determine the admission outcomes (mortality and survival) of liver diseases among patients admitted at Lira Reginal Referral Hospital in the last five years.
4. To determine the factors associated with the admission outcomes (mortality and survival) of patients admitted with liver disease at LRRH in the last five years.

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-degree Award
SHAMIM NAMUKASA
ID:
Prevalence of Sickle Cell Trait and Needs Assessment for Up-Take of Sickle Cell Screening Among Secondary School Students in Kampala City
REFNo: SS818ES

To explore the stakeholders' perceptions regarding the uptake of sickle cell screening among secondary school students in Kampala City,To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,To determine the prevalence of sickle cell trait among secondary school students in Kampala City,Determine the prevalence of sickle cell trait among secondary school students and identify student-related and stakeholders' factors influencing up-take of sickle trait screening,3. To Explore the stakeholders' perspectives regarding the uptake of sickle cell screening services among secondary school students in Central Uganda.,2. To Assess the factors influencing uptake of sickle cell screening services among secondary school students in Central Uganda.,1. To determine the proportion of sickle cell among secondary school students in Central Uganda.,
 Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
Grace Lubega Biyinzika
ID: UNCST-2020-R014149
 Perceptions and adherence to preventive measures for Coronavirus Disease 2019 among rural community households in Wakiso district, Uganda.
REFNo: SS819ES

3. To explore community barriers and facilitators of adherence to COVID-19 preventive measures among rural community households.,2. To assess adherence to COVID-19 preventive measures as issued by the Government of Uganda among rural community households.,1. To assess perceptions towards COVID-19 preventive measures among rural community households. ,To assess community perceptions and adherence to COVID-19 preventive measures in rural community households of Wakiso district, Uganda in order to provide essential information needed by public health officials and other stakeholders to make an informed decision on the most effective strategy for reduced community transmission.,
 Uganda 2021-05-20 2024-05-20 Social Science and Humanities Non-Clinical Trial Non-degree Award
MISAKI WAYENGERA
ID:
Prevalence of Polymorphic genes of Alzheimer disease in Nodding disease Tauopathy.
REFNo: HS726ES

To determine if polymorphisms in the eight common genes associated with Alzheimer Disease (APP, MAPT, PREN-1, PREN-2, BACE-1, BACE-2, IDE, and APOE-ε4) are present in DNA of Nodding Disease patients
 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
Obondo Sande James
ID: UNCST-2019-R000241
 Selecting Single Component Adjuvants for Vaccine Formulations
REFNo: HS821ES

1. To determine if adjuvants induce maturation of dendritic cells from healthy donors, LTBI and asymptomatic VL
2. To determine if adjuvants induce antigen-independent proliferation of different lymphocyte populations from healthy donors, LTBI and asymptmatic VL.
3. To measure levels of cytokine production induced by the different adjuvants
4. To determine if adjuvants induce cytotoxicity (as measured by annexin V).

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Idro
ID: UNCST-2021-R013599
 Neurodevelopmental, Behavioural and Physical Growth Outcomes of Children born to Mothers with Nodding Syndrome in Northern Uganda.
REFNo: HS852ES

Primary Objective
To determine the neurodevelopmental and behavioural outcomes of children born to mothers suffering from nodding syndrome compared to children of healthy mothers.

Secondary Objectives
1.To describe adverse medical conditions children of mothers of nodding syndrome have experienced from birth
2.To determine physical growth outcomes among children born to NS patients.
3.To determine the effect of seizure burden (frequency and duration) during pregnancy on child neurodevelopmental outcomes.
4.To determine the effect of caregiver emotional wellbeing on child neurodevelopmental outcomes.

 Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Non-degree Award
Wilson  Tumuhimbise
ID:
A mobile health framework for public private mix in Tuberculosis prevention and care in Uganda
REFNo: HS963ES

1). To explore the barriers and motivators to private hospital engagement in TB care among private healthcare workers with particular focus on understanding the current Public Private Mix frameworks utilized.
2). To develop a mobile phone based framework for enhancing the tracking of TB patients referred from private to public hospitals and assess its initial acceptability and feasibility
3). To assess the preliminary impact of the mobile phone based framework on TB patients’ adherence to referrals for TB diagnosis and treatment in public hospitals.

Uganda 2021-05-18 2024-05-18 Medical and Health Sciences Degree Award
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