Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Irene Kahimakazi
ID:
Prevalence and factors associated with gestational diabetes mellitus among women attending antenatal care at Mbarara Regional Referral Hospital
REFNo: SS854ES

1. To determine the prevalence of gestational
diabetes mellitus among women attending antenatal
care clinic at Mbarara Regional Referral
Hospital South Western Uganda
2. To establish the factors associated with
gestational diabetes mellitus among women
attending antenatal care clinic at
Mbarara Regional Referral Hospital, south
western Uganda

Uganda 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Phocas Nyandwi -
ID:
Effect of Firm Financial Strength Factors on Income Retention of General Insurers in East Africa
REFNo: SS829ES

To determine the moderating effect of firm size on the relationship between firm financial distress factors and income retention of General insurers in East Africa,To establish the effect of earnings volatility on income retention of General insurers in East Africa,To assess how liquidity affects income retention of General insurers in East Africa,To investigate the effect of leverage on income retention of General insurers in East Africa,To determine the effect of capital adequacy on income retention of General insurers in East Africa,The general objective of the study is to investigate the effect of firm financial strength factors on income retention of General insurers in East Africa.,
Burundi 2021-05-27 2024-05-27 Social Science and Humanities Non-Clinical Trial Degree Award
Simon Arunga
ID:
Management of microbial keratitis by private pharmacies in Uganda: a study of knowledge, attitude and practice
REFNo: HS1082ES

1. To determine the Knowledge of private pharmacy workers in Uganda in the management of Microbial Keratitis.
2. To describe the current practice for the management of Microbial Keratitis among private pharmacies in Uganda .
3. To explore ways to engage local pharmacy attendants to improve referral of patients with suspected Microbial Keratitis.

Uganda 2021-05-25 2024-05-25 Medical and Health Sciences Non-degree Award
Dao Ho
ID:
Palliative Care Needs Assessment in the Emergency Department in Kiruddu Hospital
REFNo: SS796ES

Objective 1: Describe the prevalence of palliative care needs among emergency care patients. In order to assess this objective, we will conduct a palliative care needs survey with patients and health care workers in the Kiruddu Hospital Emergency Department. Objective 2: Explore and illustrate identifiable strengths as well as barriers to delivery of palliative care in the emergency department. In order to assess this objective, we will conduct one-on-one interviews with health care workers in the Emergency Department to further explore this topic.
USA 2021-05-24 2024-05-24 Social Science and Humanities Non-Clinical Trial Degree Award
Gilbert Sendugwa Sendugwa
ID:
Towards Gender Balance: Understanding the Barriers and Solutions to Include Women-Led Businesses in East Africa
REFNo: SS712ES

This research will document policies and practices that exclude and include women-led businesses in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda. Specifically, it aims to: - Understand the participation of and challenges facing women-led businesses and sole proprietorships in the five countries and regionally. - Identify measures being implemented or tested to improve fairness and inclusion of women in public procurement in the selected countries. - Assess the effectiveness of the measures put in place by specific governments to improve fairness and inclusion. - Recommend actionable changes to improve the current situation, based on the findings of the research and international best practice.
Uganda 2021-05-21 2024-05-21 Social Science and Humanities Non-degree Award
Joannah Nalwoga
ID: UNCST-2024-R002651
GROUP B STREPTOCOCCUS GENITAL COLONIZATION PATTERNS AMONG NON- PREGNANT WOMEN OF REPRODUCTIVE AGE AT KAWEMPE NATIONAL REFERRAL HOSPITAL
REFNo: HS728ES

General objective
To determine how colonization with GBS changes over time among non-pregnant women of reproductive age and how the changes correlate with the host immunity
Specific objectives
1. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were uncolonized at baseline
2. To describe how the GBS colonization status changes over a three months period among non-pregnant women who were colonized at baseline

3. To determine whether the concentration of GBS IgG in serum correlates with the concentration of GBS IgG at the vaginal mucosa
4. To determine whether we can predict colonization from GBS IgG concentration in blood
5. To determine whether we can predict colonization from GBS IgG concentration in the vaginal mucosa

Uganda 2021-05-20 2024-05-20 Medical and Health Sciences Non-Clinical Trial Degree Award
Hellen Kinyi Wambui
ID:
“Effect of varying ratios of dietary macronutrients on immune system function of Swiss albino mice”
REFNo: NS159ES

i. To assess the effects of varying macronutrient ratios on the nutrition status of Swiss albino mice
ii. To evaluate the effects of varying macronutrients ratios on leucocyte count, neutrophil adhesion and cytokine production of Swiss albino mice
iii. To determine the effects varying ratios of macronutrients on the production of pro-inflammatory (TNF-α, IFN-γ, IL-6) and anti-inflammatory (IL-10) cytokines in Swiss Albino mice challenged with lipopolysaccharide
iv. To evaluate the effects of varying macronutrients ratios on delayed -type hypersensitivity and antibody titers of Swiss albino mice challenged with cow red blood cells (CRBC)

Kenya 2021-05-20 2024-05-20 Natural Sciences Degree Award
Enock Matovu
ID:
Development and Evaluation of Recombinant SARS-CoV-2 Spike and Membrane Protein-Based Sub-Unit Vaccines
REFNo: NS146ES

(i) To express recombinant subunits of the RBD region of the spike protein and the M protein
(ii) To characterize the humoral and cell mediated immune response generated by the RBD region and the M protein in mouse models
(iii) To determine the safety of the vaccine candidates in mouse models
(iv) To determine the efficacy of the potential candidate vaccine in mice

Uganda 2021-05-20 2024-05-20 Natural Sciences Non-degree Award
Lena Mpalampa
ID:
FACTORS ASSOCIATED WITH PROVISION OF PHYSICAL ACTIVITY IN PRIMARY SCHOOLS IN MAKINDYE DIVISION IN KAMPALA
REFNo: SS768ES

5. To establish the school related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,4. To establish the class related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,3. To ascertain the teacher related factors associated with insufficient physical activity offered by the primary schools in Kampala during the school term?,2. To describe the various types of physical activity offered in primary schools in Kampala during the school term,1. To determine the proportion of schools offering sufficient time for PA among primary schools in Kampala during the school term,To analyse the factors associated with insufficient physical activity offered in primary schools in Makindye Division in Kampala during the school term.,
Uganda 2021-05-20 2024-05-20 Social Science and Humanities Degree Award
Katelin Wilton
ID:
Supporting Families through Community Health Workers during COVID: A feasibility and acceptability study
REFNo: SS752ES

Main objective/ purpose
The main objective of this study is to better understand coping strategies of frontline health workers, feasibility and acceptability indicators of messaging success.
Specific Objectives
The specific objectives of this study are to:
• Understand frontline health workers perspective on their stress and psychosocial wellbeing
• Understand the feasibility and acceptability of behaviorally-informed SEL and MHPSS messaging targeted at adult and child clients delivered through frontline health workers
• Determine whether such messaging targeted at clients may also improve frontline health worker coping strategies

USA 2021-05-20 2024-05-20 Social Science and Humanities Non-degree Award
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