Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Fred  Okuku Machyo
ID:
EVALUATING THE INTEGRATION OF PEGFILGRASTIM FOR THE MANAGEMENT OF CHEMOTHERAPY-INDUCED FEBRILE NEUTROPENIA AT THE UGANDA CANCER INSTITUTE
REFNo: HS8034ES

1. To assess the feasibility and uptake of pegfilgrastim prophylaxis among eligible adult chemotherapy patients at UCI, including reach, fidelity, and vial utilization patterns.
2. To compare clinical outcomes, specifically FN incidence, infection-related hospitalizations, and chemotherapy dose delays or reductions, between pegfilgrastim recipients and historical cohorts managed without routine G-CSF prophylaxis.
3. To document baseline filgrastim prescribing patterns, dosing practices, and associated clinical outcomes prior to pegfilgrastim integration.
4. To evaluate healthcare workers’ knowledge, attitudes, and perceptions regarding FN prevention and the comparative use of pegfilgrastim versus filgrastim.
5. To identify system-level, provider-level, and process-level barriers and facilitators influencing pegfilgrastim implementation and long-term sustainability within UCI.

Uganda 2026-07-09 19:40:59 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Joan Busingye
ID: UNCST-2026-R026289
COGNITIVE BEHAVIORAL INTERVENTIONS AND PATIENT RECOVERY AMONG INDIVIDUALS WITH MENTAL ILLNESS. A CASE OF SELECTED HOSPITALS IN CENTRAL UGANDA
REFNo: SS5507ES

1. To determine the influence of cognitive interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
2. To assess the effect of emotional interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
3. To examine the influence of behavioral interventions on patient recovery among individuals with mental illness in selected hospitals in Central Uganda.
4. To evaluate the moderating effect of patient-related factors (age, gender, diagnosis, duration of illness, treatment adherence, and cultural beliefs) on the relationship between cognitive behavioral interventions and patient recovery in selected hospitals in Central Uganda.

Uganda 2026-07-09 19:38:45 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
Development of a Rapid Fieldable Nanopore Sequencing-based Prognostic and Diagnostic Assay to Advance Clinical Management Decision-Making
REFNo: HS7987ES

- Verify harmonized sample preparation workflow from archived biospecimens for the integrated pathogen diagnostic and host-response assay that is run on the INSPIRE device - Verify functionality of integrated software and hardware required for the INSPIRE device on archived biospecimens
Uganda 2026-07-09 19:37:11 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Patrick ALUKU
ID: UNCST-2026-R025007
DETERMINANTS OF MARKET ACCESS FOR SMALLHOLDER HORTICULTURE FARMERS IN MBALE DISTRICT: A CASE STUDY OF ONION AND CARROT PRODUCERS IN WANALE SUB-COUNTY...
REFNo: A803ES

This study aims to examine the determinants of market access for smallholder horticulture farmers in Mbale district: a case study of onion and carrot producers in Wanale Sub-County. Specific objectives: The study aims to achieve the following objectives: 1. To assess the effect of market infrastructure on market access for smallholder horticulture farmers in Wanale Sub-county. 2. To examine the effect of institutional support on market access for smallholder horticulture farmers in Wanale Sub-county. 3. To determine the effect of transaction costs on market access for smallholder horticulture farmers in Wanale Sub-county. 4. To find out the other factors affecting market access for smallholder horticulture farmers in Wanale Sub-county.
Uganda 2026-07-09 19:36:00 2029-07-09 Agricultural Sciences Non-Clinical Trial Degree Award
Adalbert Aineomucunguzi
ID:
Conservation Research to Monitor Grey Crowned Cranes in Uganda through Colour Band Ringing and Aerial Surveys
REFNo: NS1291ES

1. To establish a standardized crane ringing program by fitting ELSA colour rings on 20 Grey Crowned Crane chicks annually over a five-year period.
2. To track and document movement patterns and habitat use of colour-marked cranes across breeding, foraging, and dispersal landscapes.
3. To estimate survival rates and recruitment of juvenile cranes through periodic resighting of marked individuals.
4. To generate baseline biological and ecological data (including morphometrics) to address key knowledge gaps in the species’ life cycle.
5. To strengthen evidence-based conservation planning and adaptive management for Grey Crowned Crane populations in Uganda.
6. Provide data on Grey Crowned Crane populations and their distribution in Uganda
7. Advance our understanding of landscape use (particularly agriculture) and its influence on size and distribution of crane populations
8. Identify areas where the potential exists for crane conservation interventions


Uganda 2026-07-09 19:34:31 2029-07-09 Natural Sciences Non-Clinical Trial Non-degree Award
muyunga ashiraf
ID: UNCST-2025-R021888
CUSTOMARY LAND DISPUTES ADJUDICATION AND TENURE SECURITY IN UGANDA: A CASE STUDY OF ACHOLI SUB REGION
REFNo: SS5467ES

a)To examine the legal and institutional framework governing customary land tenure adjudication in Uganda and its applicability to the Acholi context. b) To examine the jurisprudential approaches and evidentiary standards adopted by superior courts in the adjudication of customary land disputes in the Acholi sub-region. c) To assess the impact of formal judicial outcomes on tenure security within the plural adjudicatory context of the Acholi sub-region d) To propose legal and institutional reforms for strengthening the adjudication of customary land disputes and tenure security based on findings from the Acholi subregion.
Uganda 2026-07-09 19:33:37 2029-07-09 Social Science and Humanities Non-Clinical Trial Degree Award
Bashemera Birungi Brenda
ID: UNCST-2025-R021775
A Deep Learning Framework for Stroke Biomarker Detection and Prediction of Post Stroke Epilepsy in Brain CT Scans
REFNo: SIR712ES

1.Collect and curate brain CT scan image datasets. 2. Develop a deep learning segmentation model to detect stroke biomark- ers. 3. Develop a deep learning prediction model to predict the likelihood of Post Stroke Epilepsy (PSE) to a high degree of accuracy. 4. Develop Large Language Models (LLM) to provide clinical reports from the deep learning models for stroke segmentation and post-stroke epilepsy prediction.
Uganda 2026-07-09 19:30:44 2029-07-09 Engineering and Technology Non-Clinical Trial Degree Award
GRACE KANSIIME
ID: UNCST-2019-R000380
POPULATION-BASED EVALUATION OF THE EPIDEMIOLOGY OF NON-COMMUNICABLE DISEASES AND SOCIOCULTURAL CONTEXT AMONG ADULTS OF TWO RURAL POPULATIONS IN UGANDA.
REFNo: HS7934ES

To build a cohort platform of adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda, with linkage to routinely collected clinical and/or medico-administrative data at the health centre to answer pertinent research questions about NCDs. ,To determine the trends in prevalence and incidence of Diabetes Mellitus and Hypertension among the cohort participants in among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,To document the sociocultural determinants of health to inform the development of community-led strategies for health promotion and improved quality of life among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda. ,To determine the burden of known risk factors such as obesity, lifestyle, smoking and diet, associated with Diabetes Mellitus and Hypertension among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,.To determine the prevalence of Diabetes Mellitus and Hypertension and examine associated sociocultural factors among the adults living in Rubirizi Town Council in Rubirizi District in Southwestern Uganda and Kabwangasi subcounty in Butebo District in Eastern Uganda.,
Uganda 2026-07-09 19:26:55 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Raymond Alinetu
ID: UNCST-2025-R022600
PREVALENCE AND PREDICTORS OF TIME-TO-DISPOSITION AMONG ROAD TRAFFIC ACCIDENT PATIENTS AT THE EMERGENCY DEPARTMENT OF MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS7584ES

To determine the mean time-to-disposition, identify its predictors, and assess its association with early clinical outcomes among adult road traffic accident patients at the Emergency Department of Mbarara Regional Referral Hospital 1) To determine the mean time-to-disposition and the prevalence of prolonged time-to-disposition (exceeding 4 hours) among adult road traffic accident patients at the Emergency Department of Mbarara Regional Referral Hospital. 2) To identify the patient-related factors (e.g., age, injury severity, impairment), attendant-related factors (e.g., presence, relationship, decision-making capacity), and system-level factors (e.g., staffing, diagnostic service availability, time of arrival) that predict prolonged time-to-disposition among adult road traffic accident patients at the Emergency Department of Mbarara Regional Referral Hospital. 3) To determine the association between time-to-disposition and early clinical outcomes (recovery status and survival at ED disposition) among adult road traffic accident patients at Mbarara Regional Referral Hospital
Uganda 2026-07-09 19:24:38 2029-07-09 Medical and Health Sciences Non-Clinical Trial Degree Award
Moffat  Nyirenda Joha
ID: UNCST-2020-R019333
Longitudinal Study of Oculomics in the General Population Cohort, Uganda Africa Oculomics Research Programme
REFNo: HS7940ES

Primary Objective: Our vision is to unlock the potential of Oculomics to better understand, diagnose and predict non-communicable disease (NCDs), to improve health outcomes and equity for African populations. Secondary Objectives: 1. Establish prospective ocular imaging and NCD phenotyping studies, nested within the existing General Population Cohort in Uganda. 2. Optimise artificial intelligence (AI) foundation models for ocular image analysis for this African population, and to fine-tune these models to detect several different systemic conditions. 3. Investigate cross-sectional and longitudinal associations between ocular biomarkers and major NCDs, to determine the diagnostic, prognostic and predictive potential of oculomics for these conditions. 4. Assess the prevalence, incidence, progression and risk factors for common ophthalmic conditions. 5. Report the long-term incidence, progression and risk factors for major NCDs (including CVD, Renal disease, liver disease, mental health, neurological conditions and musculoskeletal impairment).
Malawi 2026-07-09 19:22:22 2029-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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