Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Joshua Musinguzi Bazaale
ID:
Uganda Refugee Population-Based HIV Impact Assessment (RUPHIA 2021)
REFNo: HS1443ES

Primary Objectives
To estimate the following in a household-based, representative sample of adult refugees, aged 15+ years:
1) Prevalence of HIV in adult refugees in Uganda

Secondary Objectives
To estimate the following in the Ugandan refugee population aged 15+ years:

1) Prevalence of HIV viral load suppression (VLS - defined as HIV RNA <1000 copies/milliliter (mL));
2) Prevalence of HIV-related risk behaviors, knowledge, and attitudes;
3) Behavioral and demographic determinants of HIV prevalence;
4) Exposure to, uptake of and barriers to access to HIV-related services;
5) Prevalence of primary and secondary antiretroviral (ARV) drug-resistance (DR) among refugees with viral loads greater than 200 cp/ml;
6) Assess progress towards achievement of the Joint United Nations Programme on HIV and AIDS (UNAIDS) 90-90-90 targets

Uganda 2021-06-28 2024-06-28 Medical and Health Sciences Non-Clinical Trial Non-degree Award
FRED SEMITALA COLLINS
ID: UNCST-2020-R014096
ENGAGING PRIVATE COMMUNITY PHARMACIES IN EARLY TB CASE FINDING IN KAMPALA, UGANDA
REFNo: SS804ES

1.To understand the perspectives of stakeholders on TB screening to improve early TB case finding at private community pharmacies in Kampala through a formative assessment.
2.To refine components of the proposed intervention to improve early TB case finding at private pharmacies in Kampala, based on findings of the formative research in objective 1.
3.To evaluate the feasibility, fidelity, and acceptability of the intervention to improve early TB case finding at private pharmacies in Kampala using the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework.

Uganda 2021-06-25 2024-06-25 Social Science and Humanities Non-degree Award
Christine Begumisa Titianah
ID:
Unmet Need in Essential Medicines and Health Supplies in Ugandan Public Health Facilities.
REFNo: SS886ES

Our first research aims to assess the effect of shortages of selected medicines and health supplies on patients on patients in district-level MOH facilities
The following objectives will facilitate the achievement of this aim:
1. To collect data from health facility registers in order to list 100% of prescriptions written at a representative sample of MOH health facilities over 3 National Medical Stores distribution cycles.
2. To calculate how often filled, unfilled and modified prescriptions affect 100% of patients within selected districts over a 6-month time period, or 3 (as sheduled) National Medical Stores (NMS) cycles, depending on which is longer
3. To compare and contrast the availability of 59 essential medicines throughout each NMS distribution cycles
4. To compare health supply patterns for when medicines are in stock vs. out of stock and describe differences in functioning between medicines and health supplies over 3 NMS cycles.
5. To design and pilot a template approach to tracking data over a six-month period, in order to support continuous improvement in health systems in Uganda.
Our second research aim is to share data on the extent of medicine and health supply shortages with Uganda’s MOH and other stakeholders in order to inform corrective action The following objectives will facilitate the achievement of this aim:
1. To analyse the extent of medicine and health supply shortages within health facilities in MOH over a period of 6 months
2. To provide recommendations that may influence decisions that improve medicine and health supply management, benefit patients, and can be scaled to other regions.
Uganda 2021-06-25 2024-06-25 Social Science and Humanities Non-Clinical Trial Non-degree Award
Nuwagira Catherine
ID:
Propagation and Growth performance of Schkuhria pinnata L, for Optimal Phytochemical Contents and Antimalarial Activity in Uganda
REFNo: HS1516ES

Main objective
To examine the most viable propagation avenues and growth performance in relation to phytochemical contents and antimalarial activity of S. pinnata in Uganda.
Specific objectives
1. To evaluate agronomic dynamics of S. pinnata under varying climatic conditions of AEZs of Western and South Western Uganda
2. To examine the propagation potentials of S. pinnata through micro-propagation.
3. To evaluate phytochemical components and determine quantitative variations of flavonoids at four developmental stages
4. To determine acute dose and evaluate the plant age effect on antimalarial activity of S. pinnata.


Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
ONESMUS BYAMUKAMA
ID: UNCST-2021-R013826
FACTORS ASSOCIATED WITH SHORT INTERDELIVERY INTERVAL AMONG WOMEN WITH ANTECEDENT CESAREAN DELIVERY AT MBARARA REGIONAL REFERRAL HOSPITAL.
REFNo: HS1354ES

1. To determine the proportion of women with a prior antecedent cesarean delivery who present with a short interdelivery interval at Mbarara Regional Referral Hospital.
2. To determine the factors associated with a short interdelivery interval among women delivering at Mbarara Regional Referral Hospital with a prior antecedent cesarean delivery.

Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
JUSTUS BARAGEINE KAFUNJO
ID: UNCST-2020-R014150
COMPREHENSIVE REINTEGRATION ASSISTANCE FOR WOMEN WITH FEMALE GENITAL FISTULA: INTERVENTION PILOTING
REFNo: SS890ES

Aim 1: To understand the feasibility and acceptability of a pilot reintegration program for female genital fistula. Aim 2. To assess the acceptability of the pilot reintegration intervention to patients, intervention implementors. Aim 3. To assess the preliminary effectiveness of the pilot reintegration intervention.
Uganda 2021-06-24 2024-06-24 Social Science and Humanities Clinical Trial Non-degree Award
CHARLES BENSTONS IBINGIRA RUKAMBURA
ID: UNCST-2021-R008521
: NANOBODY BASED POINT OF CARE DIAGNOSTIC KIT FOR CERVICAL CANCER
REFNo: HS1414ES

This study will to generate and characterise nanobodies for early cervical cancer diagnosis targeting non-invasive biomarkers expressed in urine. Specifically, the study will , 1. Determine the expression levels of cervical cancer discriminatory urine biomarkers at different stages among cervical cancer cases, 2. Generate nanobodies cross-reactive to target cervical cancer specific biomarkers secreted in urine/cervical mucus, and 3. Develop and validate a Nb based lateral flow based multiplex biomarker detection assay for cervical cancer.
Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Harriet Akello
ID: UNCST-2021-R013785
Relationship between mental health and health work functioning during the covid-19 pandemic in Uganda
REFNo: HS1407ES

To identify connection between depression, anxiety and stress with health functioning during COVID-19 pandemic ,To determine prevalence of depression, anxiety and stress among healthcare workers during COVID-19 pandemic ,To determine relationship between mental health and health work functioning during covid-19 pandemic in Uganda,
Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Degree Award
Jackson Amone
ID:
A usability study on the knowledge and practice of a novel Medium Pressure Reservoir oxygen prototype in Uganda
REFNo: HS1497ES

Phase 2: The primary objective of the usability study is to gather clinical and BMET feedback on the use of the MPR with patients of diverse characteristics and its ability to function through power interruptions &/or in situations where there is high patient volume,Phase 1: The primary objective of the simulated use summative evaluation is to gather evidence of safe and effective use of the device to support regulatory filing.,
Uganda 2021-06-24 2024-06-24 Medical and Health Sciences Non-Clinical Trial Non-degree Award
JUDITH NASSAAZI
ID: UNCST-2023-R007664
LONG TERM EFFECTS OF ORTHOPAEDIC INJURY ON PATIENTS IN UGANDA
REFNo: HS1047ES

General Objective
To determine long-term effects of orthopaedic injury on patients in Uganda 8years following the injury.
Specific Objectives
• To determine the long-term economic impact of tibia and femur fractures on patients and their families
• To determine the health related quality of life of the patients who sustained tibia and femur fractures 8years following their injuries.

Uganda 2021-06-23 2024-06-23 Medical and Health Sciences Non-degree Award
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