Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Noeline Nakasujja
ID: UNCST-2019-R001428
ASSESSING THE IMPLEMENTATION OF THE POLICY AND REGULATIONS AGAINST SEXUAL HARASSMENT (PRASH) AT MAKERERE UNIVERSIT
REFNo: SS925ES

1. To assess the extent to which the recommendations from the 2018 committee on SM&H, and the 2018 amendments to PRASH have been implemented.
2. To conduct a dialogue among the University’s key stakeholders focused on addressing SM&H and creating a safe working and learning environment at the Makerere University.
3. To develop a set of recommendations to improve the monitoring and implementation of PRASH

Uganda 2021-07-07 2024-07-07 Social Science and Humanities Non-Clinical Trial Non-degree Award
Daniel Murokora Murokora
ID: UNCST-2024-R002689
Transition To Scale: Using the FREO2 Social Enterprise model and technology to scale up access to Oxygen in Uganda
REFNo: HS1238ES

The aim of this project is to evaluate the impact of a reliable oxygen system on improving a) oxygen reliability and affordability, b) clinical outcomes for children.

With a strong emphasis on clinical and technical training, the project activities should:
a) Improve the availability of oxygen, the detection of hypoxaemia, and the access of a sick child to oxygen when they require it
b) Reduce patient and health system costs of oxygen
c) Understand appropriateness, acceptability, and feasibility of the system in the specific context of health facilities in Western Uganda

Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Evaluation of Xpert® MTB/XDR test for susceptibility testing of Mycobacterium tuberculosis to first and second line drugs
REFNo: HS1395ES

Secondary: To evaluate factors for lab uptake o Training needs o Recording and Reporting Needs o Error rates o Proportion of results interpretable o TAT o Work flow,Assess sensitivity and specificity of Xpert® MTB/XDR test in previously stored sputum samples (previously stored) compared to the WHO-endorsed genotypic (MTBDRplus and MTBDRsl) method as a gold standard.,Assess sensitivity and specificity of Xpert® MTB/XDR test in previously stored sputum samples (previously stored) compared to the WHO-endorsed MGIT960 culture-based drug susceptibility method as a gold standard,The main objective is to independently validate the performance of the Xpert® MTB/XDR test for susceptibility testing of MTB among presumptive XDR-TB patients. The test performance indicators will be compared with current standard drug susceptibility test methods including the MGIT 960 liquid culture drug susceptibility (DST) systems, Line probe Assay and Whole genome sequencing. ,
Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Frederick Mubiru Edward
ID:
Market Research on Service Delivery Implications for a 4-month Depot Medroxyprogesterone Acetate Subcutaneous (DMPA-SC) Product
REFNo: HS1520ES

1. To explore stakeholder perceptions of client-centered communication needs for a 4-month DMPA-SC product
2. To explore potential barriers and facilitators to the introduction of a 4-month DMPA-SC product
3. To assess implications for data systems, curriculums, training, supervision, logistics, and quality assurance of introducing a 4-month DMPA-SC product

Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eugene Ruzagira
ID: UNCST-2023-R008282
The impact of COVID-19 on primary health care service provision and utilization in Uganda, Sierra Leone and the Democratic Republic of Congo
REFNo: HS1430ES

I.To determine whether COVID-19 is having an impact on the number of people seen at a selection of healthcare facilities for antenatal care, outpatient visits, routine immunisations, family planning and HIV treatment services, using routine health registration data.
II.To document primary healthcare workers’ experiences in providing care during the outbreak and to identify barriers and facilitators to primary health care provision.
III. To estimate the level of exposure to SARS-CoV-2 among healthcare workers by conducting a repeated serosurvey over a period of 4 months.
IV. To document community members’ experiences in accessing primary healthcare during the outbreak and to identify barriers and facilitators to utilisation.
V. To formulate a set of key findings and recommendations in partnership with stakeholders.

Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ronald Moses Galiwango
ID: UNCST-2024-R015239
SARS-CoV-2 infection and variants surveillance in South-central Uganda (Also known as ‘SARS-CoV-2 surveillance study’)
REFNo: HS1510ES

2.1 Primary objective
To ascertain the burden and transmission patterns of SARS-CoV-2 infection within selected communities in South-central Uganda using rapid antigen tests.
2.2 Secondary objectives
A. To survey for SARS-CoV-2 infection and variants in communities at high-risk of COVID-19 transmission in South-central Uganda through sequencing of specimens positive on both rapid antigen and RT-PCR tests.
B. To determine the acceptability of SARS-CoV-2 antigen rapid diagnostic tests among residents of South-central Uganda.
C. To assess SARS-CoV-2 transmission patterns/dynamics within households and in neighborhoods among communities in South-central Uganda.
D. To assess the burden of prior SARS-CoV-2 infection in South-central Uganda using a validated IgM/IgG antibody test.

Uganda 2021-07-06 2024-07-06 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Lauben Kyomukama Amagara
ID:
MROP-Mesh versus Desarda technique for short-term surgical outcomes in open inguinal hernia repair at Kampala International University Teaching-Hospital: A randomized controlled trial
REFNo: HS1073ES

Purpose of the study/General objective: To compare the MROP-mesh and Desarda techniques for short-term surgical outcomes in open inguinal hernia-repair among patients at Kampala International University Teaching Hospital
Specific objectives
i. To assess the perioperative factors following open inguinal hernia repair with MROP mesh versus Desarda technique at Kampala International University Teaching hospital
ii. To compare the mean operative time used for open inguinal hernia repair with MROP mesh versus Desarda technique at Kampala International University Teaching Hospital.
iii. To evaluate the occurrence rates of pain following open inguinal hernia repair with MROP mesh versus Desarda technique at Kampala International University Teaching hospital.

Uganda 2021-07-05 2024-07-05 Medical and Health Sciences Degree Award
Mary Kulabako Kulabako
ID:
Teachers burnout and students wellbeing in government aided public secondary schools in Uganda
REFNo: SS707ES

i. Examine examples and levels of burnout among secondary school teachers in selected public/government aided schools in Uganda.
ii. Explore how teacher burnout affect students’ wellbeing

Uganda 2021-07-05 2024-07-05 Social Science and Humanities Degree Award
PETER NABENDE
ID:
Improving Point-of-Care Learning for Prostate Cancer Imaging using Machine Learning
REFNo: SIR59ES

1. To develop a competence-based educational curriculum and content for teaching prostate cancer imaging tailored to the PoC.
2. To develop an ML-driven gamified interactive PoC education model for prostate cancer imaging.

Uganda 2021-07-05 2024-07-05 Engineering and Technology Non-degree Award
Adam Branch
ID:
Rethinking Vulnerability to COVID-19 Lockdowns in Gulu, Uganda
REFNo: SS786ES

Research questions
(1) Our first research question is: what are the mechanisms by which lockdowns are causing social and economic harm, in particular the hidden harms inflicted upon the most vulnerable?
(2) Our second research question is: How are people adapting to or innovating beyond lockdowns to secure livelihoods and ensure viable futures for themselves and others?
(3) How can lockdowns, and mitigation policies, be designed to minimize harm and support innovative strategies among those most vulnerable to lockdowns’ impacts?

Specific Objectives

(1) To describe the mechanisms by which lockdowns are causing social and economic harm, the hidden harms inflicted upon the most vulnerable people in urban and peri-urban areas of Gulu

(2) To explore people’s adaption to or innovation beyond lockdowns to secure livelihoods and ensure viable futures for themselves and others

(3) To explain how lockdowns and mitigation policies can be designed to minimize harm and support innovative strategies among those most vulnerable to lockdowns’ impacts

USA 2021-07-05 2024-07-05 Social Science and Humanities Non-degree Award
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