Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Franklin Higenyi
ID:
Gender and Public Health Space:A case of Female Doctor's career progression in Uganda Public Medical Services
REFNo: SS732ES

The study will investigate the factors that determine FDs’ career progression in UPMS.
1.4.1. Specific Objectives
1.4.1.1. To assess gender differences in career progression of female and male doctors in UPMS.
1.4.1.2. To analyze the socio-cultural and institutional factors that influence career progression of FDs in UPMS space.
1.4.1.3. To asses lived experiences of those who have managed to have career progression.
Uganda 2021-07-12 2024-07-12 Social Science and Humanities Degree Award
Cosmas Mwikirize
ID:
Efficacy of a Deep Learning-aided Platform for Diagnosis of Breast Cancer using Ultrasound Images in the Ugandan Population
REFNo: SIR57ES

General Objective: To develop and evaluate the efficacy of a deep learning-based computer-aided platform for screening of breast cancer in the Ugandan population. Specific Objectives: 1. To collect, and curate and label breast US data from ECUREI Radiology department. 2. To develop deep learning models for lesion detection and pixel-wise segmentation in breast US images. 3. To integrate the learned models in an offline computer-aided detection platform for breast cancer, and clinically evaluate its performance. 4. To develop and integrate learned models for breast cancer detection, in a real-time portable ultrasound imaging platform.
Uganda 2021-07-12 2024-07-12 Engineering and Technology Non-degree Award
Onesmus  Ahabwe Magezi
ID:
COMMON CAUSES OF ABNORMAL VAGINAL DISCHARGE AND ANTIBIOTIC SUSCEPTIBILITY AMONG WOMEN ATTENDING THE GYGAECOLOGICAL OUTPATIENT CLINIC OF MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS1456ES

1.To determine the common bacterial isolates among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital.
2.To describe the antibiotic susceptibility patterns of bacterial isolates among women with abnormal vaginal discharge attending the gynecological clinic of Mbarara Regional Referral Hospital.
3.To identify the factors associated with antibiotic resistance to commonly used antibiotics among women with abnormal vaginal discharge attending the gynecological outpatient clinic of Mbarara Regional Referral Hospital

Uganda 2021-07-12 2024-07-12 Medical and Health Sciences Non-Clinical Trial Degree Award
Josylin Ekochu Arimpa Bananuka
ID:
Corporate Governance Practices and Performance of Pharmaceutical Manufacturing Firms in Uganda
REFNo: SS571ES

i. To analyze the effect of corporate leadership on the performance of pharmaceutical manufacturing firms in Uganda
ii. To assess the effect of boards of directors on the performance of pharmaceutical manufacturing firms in Uganda
iii. To investigate the consequences internal control systems have on the performance of pharmaceutical manufacturing firms in Uganda

Uganda 2021-07-09 2024-07-09 Social Science and Humanities Degree Award
Francis Ocheng
ID:
Helichrysum odoratissimum: Isolation and identification of bioactive compounds and their effects on oral bacteria
REFNo: HS1441ES

2-To determine whether the isolated and purified compounds from Helichrysum odoratissimum maintain their antibacterial effects on oral bacteria,1-To isolate and identify the bioactive compounds in the plant Helichrysum odoratissimum plant extracts ,The general objective of the study is to isolate and identify the bioactive compounds in the Helichrysum odoratissimum plant extracts and also further investigate the effects of the isolated compounds on oral bacteria ,
Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Catriona  Waitt John
ID: UNCST-2019-R001068
Implementation of a "bundle of care" to improve anticoagulation control in patients receiving warfarin in Uganda and South Africa
REFNo: HS1422ES

Primary objective is to evaluate whether implementation of warfarin bundle improves time in therapeutic range

Secondary objectives are:
-To evaluate whether implementation of the warfarin bundle improves time to achieving a therapeutic INR
-Whether implementation of the warfarin bundle affects the occurrence of adverse events(death, bleeding and thrombotic events)
-whether staff find the interventions contained in the bundle acceptable
-To explore patients' experiences and acceptability of the package of care, and
-Whether the bundle represents good value for money
UK 2021-07-09 2024-07-09 Medical and Health Sciences Clinical Trial Non-degree Award
Maureen Ayikoru
ID:
REVISED PROPOSAL IN RESPONSE TO THE OUTCOME OF ROUND 1 OF COMMITTEE REVIEW OF THE PROJECT “INDIRECT IMPACTS OF COVID-19 ON HEALTHCARE SYSTEMS: A CASE STUDY OF UGANDA’S HEALTHCARE PROFESSIONALS”
REFNo: HS1524ES

To document what lessons can be learnt from Uganda’s response to COVID-19,To analyse the impact of information and communication technologies and the media, including digital, print and broadcast media in containing the COVID-19 pandemic in Uganda.,To analyse what if any, political economy factors influence misinformation, resource reallocation and prioritisation during the ongoing pandemic and to document the perceived effects on the entire healthcare system including those most vulnerable,To identify what threats COVID-19 has had on physical, psychosocial, and overall well being of HCPs and to assess what if any formal and informal coping mechanisms have so far been available to them,To generate empirical evidence on the indirect impacts of Uganda’s response to COVID-19, focusing on the healthcare professionals.,
Uganda 2021-07-09 2024-07-09 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adoke Yeka
ID: UNCST-2021-R004300
Efficacy and safety of artemether-lumefantrine, pyronaridine-artesunate, artesunate-amodiaquine and dihydroartemisinin – piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda.
REFNo: HS1363ES

The general objective of this study is to assess the therapeutic efficacy and safety of artemether-lumefantrine (AL), pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP) for the treatment of uncomplicated P. falciparum malaria in three sentinel sites in Uganda.
The primary objectives are:
• to measure the clinical and parasitological efficacy of 4 artemisinin-based combination therapies (ACT), artemether-lumefantrine (AL) Pyronaridine-artesunate (PA), artesunate-amodiaquine (ASAQ) and dihydroartemisinin-piperaquine (DP).
• to differentiate recrudescence from new infection of Plasmodium falciparum by molecular techniques.
The secondary objectives are:
• to evaluate the incidence of adverse events; and
• to determine the polymorphism of molecular markers mediating resistance for Artemsinin, Pyronaridine, Piperaquine and Lumefantrine resistance.
• to determine the blood concentration of Lumefantrine after treatment with Artemether- Lumefantrine .


Uganda 2021-07-08 2024-07-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Aubryn Sidle Allyn
ID:
Emplacing Agency in Girls' Education Practice: An Evaluation of Impact
REFNo: SS651ES

1. To evaluate the impact of CDOs’ programs on girls' Agency outcomes.
2. To understand how and why programs influence agency in adolescent girls, and what aspects of program design impede or speed this development.
3. To understand the relationship between girls’ agency and educational outcomes.
4. To evaluate the relationship between girls’ agency and teenage pregnancy incidence and determine what effect, if any, increased agency has on teenage pregnancy.
USA 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
Angelique Murorunkwere
ID:
DIAGNOSTIC DELAY AND ITS CAUSES AMONG PEDIATRIC CANCER PATIENTS AT MBARARA REGIONAL REFERRAL HOSPITAL CANCER UNIT
REFNo: SS857ES

1. To determine the average time between onset
of symptoms and diagnosis among children
with cancer at MRRH
2. To outline caregiver self-reported reasons
for delayed diagnosis among children with
cancer at MRRH
3. To establish the correlates of delayed
diagnosis among children with cancer at
MRRH

Rwanda 2021-07-07 2024-07-07 Social Science and Humanities Degree Award
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