Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
Search By Approval Date:
Clear Filter Total: 5,833
Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Jimmy, Maguru Mugisha Maguru
ID:
The ‘unexpected visitors’ and ‘good-host’ discourse: Social Accountability, Policy and Realities of Sexual and Reproductive Health of young people in two refugee settlements in Uganda
REFNo: SS828ES

1. To examine governance and accountability mechanisms of sexual and reproductive
health service delivery of the young refugees in refugee settlements in Uganda.
2. To examine the role of young refugees in the governance mechanisms of SRH and the
accountability chain and how this influences their ability to voice and to access SRH
services in refugee settings
3. To explore the challenges faced by young refugees and their coping mechanisms in
accessing and utilizing the ASRH services in refugee settlements in Uganda.

Uganda 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Degree Award
Violet Nakibuuka
ID: UNCST-2021-R003675
PREVALENCE AND FACTORS ASSOCIATED WITH HUMAN PAPILLOMA VIRUS VACCINATION AMONG ADOLESCENTS GIRLS AGED 9 TO 19 YEARS LIVING WITH HIV AT MULAGO ISS CLINIC, KAMPALA, UGANDA
REFNo: HS1436ES

1. To determine the prevalence of HPV vaccination among HIV positive adolescent girls aged 9-19 years at Mulago ISS Clinic, Kampala, Uganda.
2. To determine the factors associated with HPV vaccination among HIV positive adolescent girls aged 9-19 years at Mulago ISS Clinic Kampala, Uganda
3. To explore the perspectives, perceptions and experiences of healthcare providers, adolescent girls and their care takers at Mulago ISS Clinic regardingHPV vaccination among HIV positive adolescent girls.

Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Derry Taylor James
ID:
Learned social knowledge in chimpanzees
REFNo: NS269ES

To understand the nature of chimpanzee social knowledge and how it is acquired
UK 2021-08-11 2024-08-11 Natural Sciences Non-Clinical Trial Non-degree Award
MOSES EGESA
ID: UNCST-2025-R015361
Epitope mapping of schistosome tegument and alimentary tract proteins in humans
REFNo: HS1463ES

1. To determine the change in antibody reactivity profile of individuals of an endemic area to epitopes of tegument and alimentary tract proteins before and after PZQ treatment
2. To identify antibody reactivity to epitopes putatively associated with protection against reinfection


Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Pontiano  Kaleebu
ID: UNCST-2020-R019901
Field Performance Evaluation of the m-PIMAâ„¢ HIV-1/2 VL plasma assay in Uganda
REFNo: HS1606ES

Main objective
To evaluate the field performance of the m-PIMATM HIV-1/2 VL plasma VL in identifying virological failure (VF) in adults on ART. The performance will be compared to standard PCR assays used at UNHLs and UVRI.
2.3.2 Primary objectives
I). To evaluate the diagnostic accuracy using the sensitivity, specificity, NPV, PPV, FPR and FNR of the m-PIMAâ„¢ HIV-1/2 VL plasma assay in comparison to a reference assay of HIV-1 RNA PCR in identifying HIV-VF at the WHO recommended threshold of 1000 copies/ml for HIV-1 infected.
II). To determine the operational characteristics of the m-PIMAâ„¢ HIV-1/2 VL plasma assay, such as ease of-use of the assay using the standardized system usability scale (SUS) by laboratory and no laboratory personnel
III). To determine changes in turn-around time and ease of clinic workflow integration.
IV).To determine acceptability of the m-PIMAâ„¢ HIV-1/2 VL plasma assay by the study participants

Uganda 2021-08-11 2024-08-11 Medical and Health Sciences Clinical Trial Non-degree Award
Hiroyuki Takeshima
ID:
Introducing market-oriented horticulture farming in refugee hosting areas of Uganda: An intervention that builds resilience against emergency
REFNo: SS946ES

The objective of the proposed study is to introduce training programs to farmer groups in Northern Uganda, that aim to improve the market profitability of horticulture and thus increase incomes and employment for small farmers in these refugee-hosting regions in Uganda. Such investments are urgently needed to stabilize livelihoods in this region that has suffered through the combinations of challenges posed by the influx of refugees and other challenges including desert locust invasions, and health and economic risks caused by the COVID-19 pandemic. Specifically, the training program target fostering of lead farmers who will then further train other farmers within the community, and transform farmers’ mindset to “produce strategically to sell” rather than “produce and then sell”. Disseminating knowledge through lead farmers (also sometimes known as “model farmers” “village agents”) to a wider group of farmers has been considered an important way to reach and enhance the capacity and mindset of farmers at scale. The program will contribute to stabilizing and boosting farm incomes in vulnerable, refugee-hosting communities and will build the resilience of local livelihoods to COVID-19. The study then collects data on farmers’ market interaction activities and farm production practices before and after the training programs to assess the impacts of these training programs.
Japan 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
HAPPY WALUSAGA.G. ANNET
ID:
Patients’ Perceptions and Factors Influencing Choice of differentiated service delivery (DSD) models of care in Kampala, Uganda: A Case Study of Immune Suppression Syndrome (ISS)-Clinic Mulago
REFNo: SS957ES

1.To determine the prevalence of utilization of Community clients Led ART model of care among HIV/AIDS clients at ISS clinic- Mulago
2.To determine the factors associated with patients choice of CCLAD model of care among HIV/AIDS clients at ISS clinic- Mulago
3.To explore patients’ perceptions regarding the HIV differentiated models of care

Uganda 2021-08-11 2024-08-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Charity Okaba
ID:
Addressing barriers to HIV self-testing in the Private sector among young sexually active females and males in Uganda: A human centred design framework to developing private sector HIVST demand creation, distribution, and linkage models
REFNo: SS955ES

PSI and the Busara Center for Behavioral Economics will conduct qualitative market research that will use targeted questions to gather opinions on barriers and enablers of HIV self-testing in the private sector to uncover insights, opportunities, motivators, and unmet needs. Specifically, the research will employ in-depth interviews and focus group discussions to gather insights on both demand and supply aspects of HIVST as these relate to sexually active females and males of ages 18- 29.

Focus group discussions and in-depth interviews shall be conducted among potential beneficiaries, sexually active females and males of 18 – 29 years to better understand the perceptions and attitudes, barriers and motivators of these groups towards HIV self-testing and responding to the questions with regards to the design of interventions, including delving into the issues or experiences that exacerbate behavioral biases, thereby affecting uptake of HIVST by these populations. The focus group discussions shall consider individuals with experience of using HIV self-test kits and those without experience.
We will also conduct in-depth interviews with private pharmacists, pharmaceutical technologists, and retailers of community drug shops for an understanding of the service provider perspective in selling HIV self-test kits to the target population. In addition, we will also conduct in-depth interviews with manufacturers and distributors of HIV self-test kits to understand supply side barriers and interventions that may hinder or facilitate uptake of HIVST by the target population. Further, we will conduct in-depth interviews with Ministry of Health officials in charge of managing the national HIVST programs including regulatory mechanisms to understand policy and regulatory side barriers and interventions for rolling out HIVST in the private sector.
Uganda 2021-08-10 2024-08-10 Social Science and Humanities Non-Clinical Trial Non-degree Award
Hannah Kibuuka
ID: UNCST-2020-R014355
A parallel-group, Phase III, multi-stage, modified double-blind, multi-armed study to assess the efficacy, safety, and immunogenicity of two SARS-CoV-2 Adjuvanted Recombinant Protein Vaccines (monovalent and bivalent) for prevention against COVID-19 in adults 18 years of age and older
REFNo: HS1638ES

1. To assess, in participants who are SARS-CoV-2 naïve, the
clinical efficacy of the CoV2 preS dTM-AS03 vaccines for
the prevention of symptomatic COVID-19 occurring ≥ 14
days after the second injection.

2. To assess the safety of the CoV2 preS dTM-AS03 vaccines
compared to placebo throughout the study.
Uganda 2021-08-10 2024-08-10 Medical and Health Sciences Clinical Trial Non-degree Award
Twalib Aliku Olega
ID: UNCST-2019-R000474
Uganda Heart Institute Cardiac Catheterization Registry: Patient profile, procedural complications and long-term outcomes
REFNo: HS1081ES

1) to determine the clinical and demographic profile of patients undergoing cardiac catheterization at the UHI
2) to describe complications associated with adult and pediatric cardiac catheterization procedures performed at the UHI and
3) to describe the immediate and intermediate outcomes of patients undergoing adult and pediatric interventional cardiac catheterization at the UHI

Uganda 2021-08-09 2024-08-09 Medical and Health Sciences Non-degree Award
View Sort By:

"A prosperous Science and Technology Led Ugandan Society."