Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Susan Adakun
ID:
Comparing adherence to MDR-TB treatment among patients on self-administered therapy and those on Directly Observed Therapy: Non Inferiority Randomized Controlled Trial
REFNo: HS1796ES

Primary Objectives
1. To determine if adherence to MDR-TB treatment among patients on self-administered therapy (measured by Medication Events Monitoring System (MEMS) technology) is non-inferior to that among patients on Directly Observed Therapy (DOT)
Secondary objectives

1. To determine the correlation between serum MDR-TB drug concentrations and adherence as measured by MEMS technology


2. To compare treatment outcomes between MDR-TB patients on self-administered therapy and DOT

Uganda 2021-10-20 2024-10-20 Medical and Health Sciences Clinical Trial Non-degree Award
Winfred Naamara
ID:
Understanding social support for family caregivers of patients with schizophrenia in greater Kampala metropolitan area, Uganda
REFNo: SS1038ES

The overall objective of this study is to examine how family caregivers of patients with schizophrenia generate and experience social support in greater Kampala metropolitan area.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
Sandra Lamwaka
ID:
TOWARDS A NEWS INDUSTRY FRAMEWORK FOR TACKLING THE VICE OF BROWN ENVELOPE JOURNALISM: PERCEPTIONS OF JOURNALISTS AND PUBLIC RELATIONS PRACTITIONERS IN UGANDA
REFNo: SS1014ES

1. To examine journalists and PR practitioners’ perception of the brown envelope. 2. To identify the various forms that BEJ takes in Uganda. 3. To find out journalists and PR practitioners' perceptions on why BEJ is prevalent and enduring in Uganda. 4. To find out journalists and PR practitioner's perspectives on the policies that the media industry can employ to address the practice of BEJ in Uganda.
Uganda 2021-10-19 2024-10-19 Social Science and Humanities Non-Clinical Trial Degree Award
JANISCH Judith Judith
ID:
Ecological influences on Locomotor Performance in Free-Ranging Primates: a phylogenetic investigation
REFNo: NS299ES

- to investigate the evolution of arboreal locomotion in primates and discern which aspects of the arboreal environment most directly influence their locomotor performance.
- to describe kinematics of different primate species (Cercopithecus mitis, Cercopithecus ascanius, Cercopithecus lhoesti, Chlorocebus aethiops,
Lophocebus albigena, Papio anubis, Colobus guereza and Piliocolobus badius) in
their natural habitat and analyze the variation in a phylogenetic context.

Austria 2021-10-19 2024-10-19 Natural Sciences Non-Clinical Trial Non-degree Award
Sheila Balinda Nina
ID: UNCST-2021-R013804
Exploration of the Virologic Characteristics of Recently Transmitted HIV-1 Viruses in Uganda and Kenya
REFNo: HS1635ES

1. To identify key unique molecular features of T/F virus strains and characterize them
2. To relate these unique genetic features to viral protein structures and in vitro virus phenotypes.
3. To determine the difference between HIV-1 co-receptor usage of the T/F virus variants and NT virus strains.
4. To determine particle infectivity of T/F virus strains in comparison to that of the NT virus strains.
5. To compare the resistance of T/F virus strains to the antiviral effects of type I interferons to that of the NT strains
6. To determine the sensitivity of T/F virus strains to broadly neutralizing antibodies in comparison to the non-transmitted virus strains.
Uganda 2021-10-15 2024-10-15 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Noah Kalengo
ID:
LIVED EXPERIENCES OF UNCIRCUMCISED POKOT WOMEN IN AMUDAT DISTRICT
REFNo: SS1046ES

To explore the characteristics of uncircumcised Pokot women in Amudat District.

To explore the psychosocial experiences of uncircumcised Pokot women in Amudat District.

To analyze the protective factors/coping resources among the uncircumcised Pokot women that enable them to survive despite their experiences.

Uganda 2021-10-15 2024-10-15 Social Science and Humanities Non-Clinical Trial Degree Award
Joseph  Matovu KB
ID: UNCST-2020-R014654
Feasibility and acceptability of integrating PrEP and safer conception messaging into assisted partner notification
REFNo: HS1625ES

To examine the feasibility and acceptability of integrating gain-framed vs. loss-framed messages on PrEP and safer conception into the assisted partner notification (APN) program in Uganda
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nathan Kenya-Mugisha
ID: UNCST-2021-R013752
Smart Triage + QI: A digital triaging platform to improve quality of care for critically ill children
REFNo: HS1745ES

To identify and examine opportunities for ongoing improvement to strengthen the health system. ,To enable healthcare workers to recognize the most urgent children more rapidly and allocate existing resources more efficiently,To implement Smart Triage + QI to improve the quality of care at three UCMB health care facilities and Gulu Regional Referral Hospital (a government facility). ,
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
Uganda Paediatric and Adolescent HIV Cohort on Antiretroviral Therapy: Study Protocol (UP-ART)
REFNo: HS1699ES

The objectives of this study are to:
1) Describe the characteristics of children and adolescents living with HIV receiving paediatric care in the participating centres and coverage of ART
2) Describe the uptake of new antiretroviral drugs such as DTG across age groups and regions
3) Assess the effectiveness and safety of new antiretroviral drugs such as DTG, including viral suppression, incidence of adverse events, serious adverse events and discontinuation of drug
4) Assess broader clinical outcomes including retention in care, mortality, disease progression, immune response, viral suppression, overall and by age and treatment regimen/treatment history
5) Assess (i) the prevalence of HIV drug resistance among children/adolescents start of treatment and the impact on treatment response, and (ii) among those who experiencing virological failure on DTG to describe the risk of accumulation of drug resistance (see sub-study Section 4).

Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Clinical Trial Non-degree Award
Isaac Ssewanyana
ID: UNCST-2020-R014336
Integration of phone-based data capture tool to support real-time reporting and quality assurance of SARS-CoV-2 Ag RDT in Uganda
REFNo: HS1723ES

1. To pilot the integration of phone-based data collection tool and real-time reporting via a dashboard
2. To monitor quality and post-market surveillance of the Ag RDT in Uganda
3. To demonstrate the use of remnant Ag RDT samples in the routine surveillance of SARS –CoV-2 variants in Uganda
Uganda 2021-10-14 2024-10-14 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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