Manjari Quintanar-Solares
ID:
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MICROARRAY PATCH FOR PEDIATRIC ANTIRRETROVIRAL TREATMENT STAKEHOLDER INTERVIEWS IN UGANDA
REFNo: HS1359ES
To define the target product profile (TPP) and preferred user characteristics, identify stakeholder needs, and evaluate potential acceptability of a pediatric ARV MAP
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Mexico |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Eun Seok Kim
ID:
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Cross-sectional prevalence study of schistosomiasis and soil-transmitted helminthiasis with nested open-label randomised controlled study of evaluating the impact of fatty meal co-administration and double-dosing on albendazole effectiveness against hookworm infection among school-aged children in Mayuge district: Implications for Mayuge NTDs Elimination (MANE) Project
REFNo: HS1411ES
Objective 1: To determine the effect of albendazole administration with a fatty meal such as avocado, versus albendazole administration without a fatty meal, on hookworm cure rate and egg reduction rate.
Objective 2: To determine the effectiveness of dual-dose (400mg/day, two consecutive days) versus single-dose (400mg) albendazole treatment regimens on hookworm cure rate and egg reduction rate.
Objective 3: To identify and evaluate environmental, social and cultural variables affecting hookworm infection, and cure rate and egg reduction rate of albendazole against hookworm.
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South Korea |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Clinical Trial |
Degree Award |
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Carmen Logie
ID: UNCST-2021-R013185
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Kuwawezesha Vijana (Empowering Youth): An HIV Self-Testing and Comic Intervention with Refugee Adolescents and Youth in a Refugee Settlement in Northern Uganda
REFNo: SS884ES
The primary study aim is to compare the effectiveness of adding HIV self-testing, education- comics, or both to the standard of care approaches of HIV testing among refugee youth in Bidi Bidi in increasing HIV status knowledge.
The primary outcome is HIV testing uptake (HIV status knowledge, verified through asking HIV serostatus and verifying with voluntary point of care testing).
The secondary outcomes include HIV knowledge, HIV-related stigma, use of SRH services (e.g., condoms, contraception), and linkage to a clinic for confirmatory testing.
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Canada |
2021-08-16 |
2024-08-16 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Doris Kakuru
ID:
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Representation of Young Motherhood: Performing young womanhood, subjectivities and agency in Sexual and Reproductive Health in Uganda
REFNo: SS960ES
To find out the implications of representations of young motherhood on reproductive justice,To establish alternatives of young parenthood which are made available through motherhood performances by young mothers in Uganda (Including their lived experiences, identity formation and agency to adhere, comply or resist dominant subjectivities). ,To examine how dominant notions about young motherhood affect SRHR rights of young mothers in Uganda.,To ascertain how dominant assumptions of young motherhood by different SRHR actors position young mothers in urban poor locales in Uganda. ,
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Uganda |
2021-08-16 |
2024-08-16 |
Social Science and Humanities |
Non-Clinical Trial |
Degree Award |
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Rosalind Parkes-Ratanshi Parkes
ID: UNCST-2019-R000717
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Acceptability and feasibility of mhealth technology for sensitization and contact follow up for high-risk communities for infectious disease outbreaks; Call for Life-COVID (CFL-C) and Call for Life Ebola (CFL-E)
REFNo: SS865ES
1.To document experiences of using an IVR service to support COVID positive patients and for those in COVID quarantine.
2.To evaluate the acceptability of using an IVR service for post COVID-19 mental health screening in Uganda.
3.To assess feasibility of using an IVR service for outbreak response, through documentation of the experience and lessons learned of using CFL-C by health care workers, policy makers, developers and implementing actors
4.To explore barriers and enablers to health seeking behaviour and vaccinations, perceptions/ stigma/ fears/concerns of COVID and other epidemic outbreaks including EVD and mitigation measures (e.g. cancelling funerals – Ebola, school and business closures – COVID, including comparisons of the two) within at risk and hard to reach communities.
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UK |
2021-08-16 |
2024-08-16 |
Social Science and Humanities |
Non-Clinical Trial |
Non-degree Award |
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Stella Muyanja Zawedde
ID: UNCST-2021-R014037
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Computer aided detection of Tuberculosis using chest radiography: A clinical validation of the CAD4TB version 7 system.
REFNo: HS1575ES
The primary objective will be to:
a) To determine the sensitivity and specificity of different CAD4TB v7 scores for the detection of bacteriologically confirmed tuberculosis (using Xpert Ultra® as the reference standard) in the Ugandan population.
The secondary objectives will be to
b) To determine the optimal combination of symptoms and chest x-ray features to be used to when triaging patients at the outpatient and HIV clinics.
To determine the most cost-effective algorithm to be used while to screen for TB among patients presenting to the outpatient and HIV clinics in Gulu and Kitgum.
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Uganda |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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VICTOR TUMUKUNDE SPECTOR
ID:
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Assessment of the validity of the measurement of kangaroo mother care duration in a hospital in Uganda: an observational study
REFNo: HS1589ES
o To assess the accuracy of caregiver report on duration of skin-to-skin contact (SSC) in the KMC position among neonates ≤2000g before stabilization.
o To assess the accuracy of healthcare workers’ report on duration of SSC in the KMC position among neonates ≤2000g before stabilization.
o To assess the reproducibility of the two methods of measuring KMC duration.
o To assess the reliability (inter-observer agreement) of gold standard direct observation.
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Uganda |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Degree Award |
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Stephen Watya
ID: UNCST-2025-R021507
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UNDERSTANDING PROSTATE CANCER IN MEN OF AFRICAN ANCESTRY.
REFNo: HS1514ES
GENERAL OBJECTIVE
The goal of this project is to understand the genetics and epidemiology of prostate cancer in men of African ancestry.
Specific Objectives (SO):
1. To study common and rare germline variation in association with prostate cancer risk in men of African ancestry, using cutting edge genotyping and sequencing techniques. (UGPCS)
2. To determine non-genetic risk factors associated with prostate cancer among men of African ancestry. (UGPCS)
3. To identify germline and tumor genomic/molecular determinants of aggressive prostate cancer and disease progression in men of African ancestry. (UGPCS)
4. To determine the acceptability and validity of a rapid screening kits for prostate cancer in the Ugandan population. (UGPCS-epi)
5. To assess population level determinants of high PSA (≥4 n/gm) in men of African ancestry (UGPCS-epi).
6. To explore whether circulating tumor cells and circulating tumor DNA can be detected in the blood of men with aggressive prostate cancer and may be used to screen for aggressive disease (UGPCS-screen).
7. To determine disease progression of prostate cancer from the time of presentation among Ugandan men. (UGPCS-screen).
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Uganda |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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Violet Korutaro
ID: UNCST-2019-R000618
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IMPAACT 2017: Phase I/II Study of the Safety, Acceptability, Tolerability, and Pharmacokinetics of Oral and Long-Acting Injectable Cabotegravir and Long-Acting Injectable Rilpivirine in Virologically Suppressed HIV-Infected Children and Adolescents. Short title: ‘MOCHA’ (More Options for Children and Adolescents), DAIDS # 30070, IND # 138,754
REFNo: HS1512ES
To assess the safety of CAB LA + RPV LA through Week 24 in HIV-infected, virologically suppressed adolescents,To confirm the doses for oral CAB followed by injectable CAB LA in HIV-infected, virologically suppressed adolescents by evaluating: Safety and multiple dose PK of oral CAB through Week 4, Safety and multiple dose PK of CAB LA through Week 16, and to confirm doses for injectable RPV LA in HIV-infected, virologically suppressed adolescents by evaluating safety and multiple dose PK of RPV LA through Week 16,To confirm the dose and evaluate the safety, tolerability, acceptability, and pharmacokinetics (PK) of oral cabotegravir (CAB), long-acting injectable cabotegravir (CAB LA), and long-acting injectable rilpivirine (RPV LA) in virologically suppressed HIVâ€1 infected children and adolescents aged 12 to <18 years.,
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Uganda |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Clinical Trial |
Non-degree Award |
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Helen Ndagije Byomire
ID: UNCST-2021-R013939
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Skepticism on the Safety and Quality of Generic Medicines from countries with Non-stringent Regulatory Authorities in Uganda.
REFNo: HS1550ES
3. To establish knowledge, attitude and perceptions of health workers and the general population towards generic medicines from countries with the SRAs and those from the N-SRA including Uganda.,2. To compare the quality of selected registered generic medicines on the Ugandan market sourced from countries with SRAs and those from N-SRA including Uganda against the innovator product. ,1. To compare the nature and proportion of adverse drug reactions (ADRs) received by NDA in the period of June 2016 to June 2020 for selected generics from SRAs and those from the N-SRA against the innovator product.,To compare the quality and safety of selected generic medicines on the Ugandan market sourced from countries with Stringent Regulatory Authorities (SRAs) with those from non-stringent regulatory authorities N-SRAs including Uganda. ,
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Uganda |
2021-08-16 |
2024-08-16 |
Medical and Health Sciences |
Non-Clinical Trial |
Non-degree Award |
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