Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Felix Magala
ID: UNCST-2024-R016043
Incidence of Post-Operative Sore Throat Among Patients Undergoing Open Abdominal Surgery: A Randomized Control Trial Comparing Video and Direct Laryngoscopy
REFNo: HS5685ES

To compare the incidence of POST, and recovery from POST following intubation using Video laryngoscopy or Direct laryngoscopy during general anaesthesia among general surgery patients undergoing laparotomy at MRRH
1. To determine the incidence of POST in the first 24 hours following intubation with either Video-laryngoscopy or Direct-laryngoscopy for patients undergoing open abdominal surgery at MRRH
2. To determine the recovery time from POST among patients intubated with Video laryngoscopy compared to Direct-laryngoscopy.
3. To describe the symptoms associated with POST amongst patients intubated for open abdominal surgery
Uganda 2025-07-11 18:00:56 2028-07-11 Medical and Health Sciences Clinical Trial Degree Award
Josephine Tumuhamye NONE
ID: UNCST-2024-R015885
Rapid detection of neonatal bloodstream infections using next generation sequencing in Uganda
REFNo: HS5942ES

1. To estimate the proportion of neonates with a possible bloodstream infection with culture-negative sepsis in whom (a) pathogen(s) is identified using NGS 2. To compare the proportion of neonates with a positive blood culture test versus the proportion of neonates with a positive next-generation sequencing test. 3. To compare the sensitivity and specificity of Blood Culture and NGS in identifying (a) pathogen(s) of possible bloodstream infection compared to a composite reference standard (consisting of all microbiological tests and clinical adjudication)
Uganda 2025-07-11 17:59:54 2028-07-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Opiyo Solomon
ID: UNCST-2025-R018201
Role of Public Libraries in Smart Cities in Uganda
REFNo: SS3927ES

1) Examine the extent to which public libraries are integrated into the technological infrastructure of Smart Cities.
2) Investigate how public libraries support/engage with the Community to foster innovative participation/interaction with Smart City Initiatives.
3) Determine whether public libraries\' involvement in smart city development is significant.
4) Develop recommendations for enhancing the role of public libraries in developing Smart Cities.
Uganda 2025-07-11 17:56:57 2028-07-11 Social Science and Humanities Non-Clinical Trial Degree Award
MUWANGUZI MOSES
ID: UNCST-2021-R013695
Early childhood adversities, resilience and HIV care outcomes among adolescents and young adults living with HIV in rural Uganda
REFNo: HS6168ES

1) To determine relationship between ACEs and HIV treatment outcomes (ART adherence and retention in HIV care) among AYLHIV at the HIV adolescent clinic in southwestern Uganda. 2) To determine the mediating role of resilience on the relationship between ACEs and HIV treatment outcomes (ART adherence and retention in HIV care) among AYLHIV at the HIV adolescent clinic in southwestern Uganda.
Uganda 2025-07-11 17:55:44 2028-07-11 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Adrian  Kakinda Ivan
ID: UNCST-2024-R015907
Exploring Perceived Barriers and Facilitators to Formal and Informal Mental Health Help-Seeking Behaviours of School-Going Adolescents in Uganda.
REFNo: SS4060ES

General Objective To explore the perceived barriers and facilitators of formal and informal mental health help-seeking behaviours among school-going adolescents in Uganda. Specific Objectives 1.To identify common MHPs affecting school-going adolescents in Uganda and their impact on their daily functioning. 2.To examine the perceived barriers to formal and informal mental health help-seeking behaviours among school-going adolescents. 3.To explore the facilitators that encourage mental health help-seeking behaviours among school-going adolescents. 4.To assess the role of mental health literacy and stigma in influencing adolescents' help-seeking behaviours.
Uganda 2025-07-11 17:53:17 2028-07-11 Social Science and Humanities Non-Clinical Trial Degree Award
Martin Ariapa
ID: UNCST-2021-R013296
HOW DOES AGENCY TRANSLATE INTO ACTION? UNDERSTANDING THE MECHANISMS OF TEACHER AGENCY AND WELL-BEING IN UGANDA
REFNo: SS4031ES

The main objective of the study is to understand how teacher agency translates into action and its relationship with teacher well-being among primary school teachers in Uganda The study aims to address the following specific objectives: (i) To establish the reliability and validity of the teacher agency measurement tool. (ii) To examine the relationship between teacher agency and teacher well-being. (iii) To examine the relationship between teacher agency and the socially recognised actions teachers undertake in their schools.
Uganda 2025-07-11 17:51:27 2028-07-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jedediah Silver
ID: UNCST-2023-R007939
Uncertainty and Incentives for Quality Upgrading: Evidence from Ugandan Cassava
REFNo: SS4053ES

Our project is designed to answer two main research questions:
1. How does increasing access to small-scale processing technology affect the supply of food crops to commercial value and investments in quality, at both the farmer and trader level?
2. How does reducing exposure to output market risk affect demand for quality-upgrading technology, at both the farmer and trader levels?

USA 2025-07-11 17:41:00 2028-07-11 Social Science and Humanities Non-Clinical Trial Non-degree Award
WEKOYE CORNEL
ID: UNCST-2024-R016586
Policy Environment and the Participation of Persons with Disabilities in the Administration of Primary Schools in Uganda
REFNo: SS3984ES

To examine the administrative structures’ influence on PWDs participation in the administration of primary schools in Uganda.
2. To determine the level of participation of persons with disabilities in administration of primary schools in Uganda.
3. To determine the relationship between the policy environment and participation of PWDs in administration of primary schools in Uganda.
4. To create a framework of strategies to support the participation of PWDs in administration of primary schools in Uganda.

Uganda 2025-07-11 17:30:39 2028-07-11 Social Science and Humanities Non-Clinical Trial Degree Award
Dithan Kiragga
ID: UNCST-2025-R018677
Assessing the multifaceted factors influencing HIV Pre-Exposure Prophylaxis (PrEP) uptake and continuation among young women aged 15-24 years in Mulago, Uganda.
REFNo: HS6230ES

This study investigates factors influencing the uptake and continuity of PrEP among young women in Uganda. The research is divided into three manuscripts. Manuscript 1 focuses on the relationship between the perceived susceptibility to HIV, the socio-demographic factors of the PrEP clients, and the uptake of PrEP among young women. Manuscript 2 investigates the association between HIV behavioral risk factors, perceived benefits of PrEP, and PrEP uptake among young women. Manuscript 3 assesses the impact of the PrEP service delivery mode (health facility-based or community-based) on the continuity of PrEP among young women.
Uganda 2025-07-11 17:27:21 2028-07-11 Medical and Health Sciences Non-Clinical Trial Degree Award
Korenilo Duot Ajang
ID: UNCST-2024-R016022
Environmental Law Compliance on Oil and Gas Exploration and Production in South Sudan: An Analysis
REFNo: SS4125ES

iii. To analyze the compliance of oil and gas exploration and production in South Sudan with international best practices on the environment,ii. To examine the environmental protection mechanisms for oil and gas exploration and production in South Sudan.,i. To establish the legal framework governing critical environmental issues in oil and gas exploration and production in South Sudan.,The main objective of the study will be to analyze environmental law compliance regarding oil and gas exploration and production in South Sudan.,
South Sudan 2025-07-11 17:18:38 2028-07-11 Social Science and Humanities Non-Clinical Trial Degree Award
Mildred  AKANDINDA
ID: UNCST-2023-R005963
FACTORS AFFECTING TURNAROUND TIME OF POSTGRADUATE RESEARCH ETHICS APPROVAL AND THE PERCEPTIONS OF GRADUATE STUDENTS ON THE REVIEW PROCESS IN SOUTHWESTERN UGANDA
REFNo: SS3996ES

To determine the turnaround time of research ethics approval of postgraduate research proposals at MUST and KIU-WC.
ii. To explore the factors affecting the turnaround time of research ethics approval of postgraduate research proposals at MUST and KIU-WC.
iii. To assess the perceptions that postgraduate students have on the research ethics approval process at MUST and KIU-WC.

Uganda 2025-07-10 18:50:06 2028-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
HERBERT CHERUKUT
ID: UNCST-2025-R017737
Leveraging Wearable Technology and Machine Learning for Predictive Monitoring and Management of Diabetes in Kampala, Uganda (DIABETECH-Study)
REFNo: HS5869ES

1. To conduct a pilot study to assess the feasibility of measuring behaviours objectively, such as physical activity, dietary habits, stress levels and sleep patterns using wearable devices and food-intake app among adults living in Kampala, Uganda.

2. To assess the impact of behavioural factors (physical activity, food intake, stress, sleep, as measured using wearable technology) and infectious diseases (malaria and upper respiratory infections) on blood glucose levels (as measured by Continuous Glucose Monitors (CGMs)) among diabetic patients in Kampala, Uganda.

3. To integrate and visualize behavioural data from smartwatches (physical activity, stress, sleep) and a food-intake app with the blood glucose data from Continuous Glucose Monitors (CGMs) into a user-friendly dashboard, and providing healthcare workers and patients with clear, accessible summaries to aid diabetes management in Kampala, Uganda.

4. To develop and apply machine learning algorithms that predict blood glucose fluctuations based on behavioural factors (physical activity, food intake) and upper respiratory infections, with the aim of generating predictive insights and personalized intervention strategies for managing diabetes among adults in Kampala, Uganda.


Uganda 2025-07-10 18:39:38 2028-07-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Namara Mable
ID: UNCST-2022-R010662
Assessment of Quality Assurance Practices on Performance of Graduates of selected Private Universities in Western Uganda
REFNo: SS2465ES

To assess the contribution of accredited programs to performance of graduates
2 To analyse the contribution of monitoring/evaluation to performance of graduates
3. To evaluate the effect of quality of teaching staff on performance of graduates
4. To evaluate the effect of external assessment on performance of graduates

Uganda 2025-07-10 16:59:02 2028-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
NASSIFU SSEMWANGA
ID: UNCST-2022-R010829
Developing a framework for integrating continuous professional education on the Uganda Nurses and Midwives’ Council mandate within healthcare institutions
REFNo: HS6185ES

i. To explore the nurses’ and midwives’ understanding of the mandate of the UNMC.
ii. To assess the nurses’ and midwives’ level of knowledge regarding the mandate of the UNMC.
iii. To explore barriers to continuous professional development among nurses and midwives in Uganda
iv. To develop a framework for integrating continuous professional education on the UNMC mandate within healthcare institutions

Uganda 2025-07-10 16:56:59 2028-07-10 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ASHIRAF MABANJA
ID: UNCST-2025-R018962
Emotional Intelligence Critical thinking, and Doctoral Success in Ugandan universities
REFNo: SS4035ES

i.To analyze the influence of emotional intelligence on doctoral success in Uganda universities. ii.To analyze the influence of critical thinking on doctoral success in Uganda universities. iii.To analyze the combined influence of emotional intelligence and critical thinking on doctoral success in Ugandan universities. iv.To compare the levels of emotional intelligence between doctoral graduates who completed their studies on time and those who experienced delays in completion. v.To compare the levels of critical thinking between doctoral graduates who completed their studies on time and those who experienced delays in completion.
Uganda 2025-07-10 16:54:51 2028-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Mike Kyewalyanga
ID: UNCST-2021-R013531
FACILITATORS AND BARRIERS OF EXCLUSIVE BREASTFEEDING AMONG MOTHERS WITH YOUNG INFANTS IN MBARARA CITY
REFNo: HS6152ES

1.To determine the magnitude of exclusive breastfeeding among mothers with young infants in Mbarara City.
2.To describe the commonest modes of feeding among young infants in Mbarara City.
3.To explore facilitators and barriers to exclusive breastfeeding among mothers with young infants in Mbarara City.

Uganda 2025-07-10 14:24:00 2028-07-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Mary Samantha
ID: UNCST-2025-R017849
Potential effectiveness, Feasibility, and Acceptability of an Implementation Strategy for Alcohol Use Disorder Management by Primary Healthcare Providers: A case of Isingiro District
REFNo: SS4085ES

1. To Co-design an implementation strategy for AUD management by PHC providers guided by Consolidated Framework of Implementation Research (CFIR) in the Isingiro district 2. To evaluate the potential effectiveness of an implementation strategy for AUD management measured by the number of AUD cases recorded by PHC providers in the Isingiro district. 3. To assess the feasibility and acceptability of an implementation strategy for AUD management measured by ease of use and approval by PHC providers in the Isingiro district.
Uganda 2025-07-10 14:20:54 2028-07-10 Social Science and Humanities Non-Clinical Trial Degree Award
Robert Muyinda
ID: UNCST-2025-R019365
BIOREMEDIATION OF AFLATOXIN IN SELECTED FOODS AND ANIMAL FEEDS USING LIGNINOLYTIC ENZYME EXTRACTS FROM SPENT SUBSTRATES OF OYSTER MUSHROOM (Pleurotus ostreatus)
REFNo: A611ES

The main objective of the study is to evaluate the postharvest practices of maize and groundnuts, aflatoxin levels, cancer risks and the biodegradation potential of ligninolytic enzyme extracts from used P. ostreatus substrates on the total aflatoxin.
1.3.2 Specific objectives
The specific objectives of the study are to:
1.Determine postharvest handling practices as drivers of AF contamination in food in Teso and Busoga subregions.
2.Determine the total AF content (AFB1, AFB2, AFG1 and AFG2) in food (maize and groundnuts products).
3.Assess dietary exposure and the risks to the consumers (adults and children) of maize and groundnuts products.
4.Determine the AFB1, AFB2, AFG1 and AFG2 levels, formed metabolites and their toxicity in food (maize) after the ligninolytic enzyme bioremediation.

Uganda 2025-07-10 14:15:03 2028-07-10 Agricultural Sciences Non-Clinical Trial Degree Award
Susan Asiimwe
ID: UNCST-2025-R016828
Improving Adolescent Reproductive Health in Uganda: Assessing Challenges and Opportunities in the Development and Implementation of Policies on Adolescent Pregnancies
REFNo: HS6231ES

1.To assess current reproductive health policies targeted at addressing adolescent pregnancies in East Africa 2.To determine the trends in prevalences and associated factors of adolescent pregnancies in Uganda using the Uganda Demographic and Health Survey (UDHS) 3.To study barriers, facilitators, and coping mechanisms for the development and implementation of selected ARH policies in Uganda. 4.To co-create feasible recommendations to improve ARH policies' content and implementation
Uganda 2025-07-10 14:09:39 2028-07-10 Medical and Health Sciences Non-Clinical Trial Degree Award
Moses  Anyit Wany
ID: UNCST-2024-R002083
PREVALENCE, ANTIMICROBIAL SENSITIVITY AND FACTORS ASSOCIATED WITH VAGINAL BACTERIAL COLONIZATION AMONG WOMEN WITH CERVICAL CANCER AT MBARARA REGIONAL REFERRAL HOSPITAL
REFNo: HS5800ES

1. To determine the prevalence of vaginal bacterial colonization among women with cervical cancer at Mbarara Regional Referral Hospital.
2. To identify the bacteria commonly isolated from the vagina among women with cervical cancer at Mbarara Regional Referral Hospital.
3. To describe the antimicrobial sensitivity of vaginal bacteria isolated among women with cervical cancer at Mbarara regional Referral Hospital.
4. To determine the factors associated with vaginal bacterial colonization among women with cervical at Mbarara Regional Referral Hospital
South Sudan 2025-07-10 14:08:02 2028-07-10 Medical and Health Sciences Non-Clinical Trial Degree Award
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