Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
JOSELYN RWEBEMBERA
ID: UNCST-2021-R013915
Rheumatic Heart Disease Community Streptococcal Treatment Program “RESET”
REFNo: HS1580ES

To improve the algorithm of the Strepic® device for Group A Strep Pharyngitis detection and then to test the performance as compared to microbiological culture (gold standard) and clinical decision rule.,To increase health seeking behavior for sore throat through a multifaceted community awareness campaign.,To improve guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based care through frontline healthcare provider education on clinical decision rules and guideline-based primary prevention.,To determine the impact of a pragmatic RHD primary prevention program in Uganda,
Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-Clinical Trial Non-degree Award
ELIZABETH NALINTYA
ID: UNCST-2021-R012882
Long title: A community-based Phase III, cluster randomized trial of point-of-care CD4 testing and enhanced screening and prophylaxis in advanced HIV disease Short title: An enhanced package of care to reduce mortality in advanced HIV disease
REFNo: HS1605ES

Primary Objectives:
1. To assess 24-week survival with retention in care in persons with advanced HIV disease (CD4<200 cells/µL) with point-of-care CD4 testing compared to standard flow cytometry
2. To assess 24-week survival with retention in care with an enhanced diagnostic OI screening and prophylaxis strategy compared to standard WHO package of care in persons with advanced HIV disease
Secondary Objectives:
1. To determine incidence of OIs
2. To measure adverse events with enhanced prophylaxis regimens
3. To assess tolerability and adherence of enhanced prophylaxis regimens
4. To determine incidence and cause of hospitalization for persons with advanced HIV disease
5. To determine cause of death for persons with advanced HIV disease
6. To determine HIV outcomes of viral suppression in persons with advanced HIV disease.
7. Measure cost, cost-effectiveness, and budgetary impact of the CD4 testing strategies, and OI screening and prophylaxis strategies.

Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Clinical Trial Non-degree Award
Graham Birch John
ID:
Title of research project: Oxidative shielding and the inter-generational costs of reproduction in male wild banded mongooses
REFNo: NS164ES

(1) To understand transgenerational influences on health and reproductive success in
wild mammals.
(2) To investigate the impact of paternal health on the development and reproductive
success of offspring, using banded mongooses as a model system.
UK 2021-09-20 2024-09-20 Natural Sciences Degree Award
Fabian Mwosi
ID:
RETIREMENT PLANNING AND SOCIO-ECONOMIC STATUS OF CIVIL SERVANTS IN BUSOGA SUB-REGION, UGANDA.
REFNo: SS843ES

i. Investigate the relationship between saving culture and socio-economic status of retired civil servants in Busoga sub-region, Uganda
ii. Examine the relationship between financial planning and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iii. Assess the relationship between lifestyle and socio-economic status of retired civil servants in Busoga sub-region, Uganda
iv. Explore the moderating effect of demographic factors on the relationship between retirement planning and socio-economic status in Busoga sub-region, Uganda
Uganda 2021-09-20 2024-09-20 Social Science and Humanities Non-Clinical Trial Degree Award
Asenath Kwagalakwe
ID:
Dry Rifting in the Albertine-Rhino graben, Uganda (DRIAR)
REFNo: NS252ES

Investigating the physics of strain accommodation in the magma-poor Albertine-Rhino Graben of the East African Rift System using geodynamic modeling and GNSS geodesy
Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Hillary Mwongyera
ID:
Dry Rifting in the Albertine-Rhino Graben (DRIAR)
REFNo: NS264ES

To conduct a geological investigation of faulting associated with continental rifting in the magma-poor rift environment in the northernmost Western Branch of the East African Rift System.
Uganda 2021-09-20 2024-09-20 Natural Sciences Non-Clinical Trial Degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
Determining the Effectiveness of Dispensing Messages (DEDIM) on Adherence and Viral Suppression among Children with an Unsuppressed Viral Load in Uganda
REFNo: HS1544ES

General Objective
To determine the effectiveness and implementation of dispensing messages on adherence and viral suppression among children with an unsuppressed viral load in Uganda

Specific objectives
1. To determine the facilitators and barriers to the delivery of dispensing messages to caregivers of children (< 15 years) living with HIV with an unsuppressed viral load in Uganda to inform the implementation strategy.
2. To assess the effectiveness of dispensing messages on outcomes of adherence and viral load suppression among children (<15 years) living with HIV with non-suppressed viral loads in Uganda.
3. To identify processes and contextual factors that explain the uptake, reach, and fidelity of delivery of ART dispensing messages to caregivers of children (< 15 years) living with HIV with unsuppressed viral load in Uganda

Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eve  Namisango
ID: UNCST-2021-R014038
The development and evaluation of a mobile phone-based intervention to facilitate continuity of care, symptom monitoring and self-management in palliative care patients in Uganda
REFNo: HS1600ES

vi. To develop best practices for patient-public engagement to empower cancer patients to support research in palliative care at different stages,v. To identify mechanisms of action for the intervention in supporting palliative care patients and their families ,iv. To determine uptake, patterns of clinical palliative care practice and factors influencing engagement with the mobile application ,iii. To deliver the novel intervention to two cohorts of palliative care patients , ii. To determine optimal implementation within routine palliative care practice at Yumbe Regional referral hospital palliative care unit and New Life Hospice ,i. To develop and evaluate a mobile phone-based (mpalliative) intervention to collect outcomes data and COVID-19, TB and hepatitis B symptoms from palliative care patients alongside developing a web-based application to communicate data to palliative care teams and facilitate continuity of care and self-management in palliative care patients in Uganda ,
Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Achilles Katamba
ID: UNCST-2019-R000540
Uganda TB Care Cascade
REFNo: HS1718ES

1. To evaluate the accuracy of DHIS2 TB surveillance data using quantitative and mixed-methods approaches. 1a. To compare the accuracy of TB quality indicators measured with aggregate data compared to those measured with individual-level data. 1b. To explore discrepancies in the DHIS2 data using qualitative interviews.
2. To use routine surveillance data to describe the quality of TB care in Uganda.
3. To measure the impact of Xpert MTB/RIF on TB indicators in Uganda.
Uganda 2021-09-20 2024-09-20 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Nelson Sewankambo K
ID: UNCST-2020-R014578
THRiVE Research Enrichment: Community and Public Engagement for Enhanced Impact
REFNo: HS1586ES

1. To enable doctoral trainees to work with young people in schools who will identify their preferred ways for engagement with THRiVE research.
2. To co-create and co-design at least one engagement project at each school led by student champions in collaboration with doctoral trainees and implemented based on one or more ways identified in objective 1 above.
3. To co-design and implement at least one student-centred drama skit and/or games for engagement of students with THRiVE doctoral trainees’ research, utilizing findings from objective one.
4. To publicize the public engagement in research work to stakeholders as a way of stimulating engagement of young people and doctoral trainees in PER.

Uganda 2021-09-17 2024-09-17 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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