Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Sina Kulwijira Sosthenes
ID:
Proportion of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
REFNo: HS1552ES

To determine proportional of episiotomy and factors associated with episiotomy among mothers delivering at Mbarara regional referral hospital
2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Muhmood Kiryowa Haruna
ID:
Periodontal disease in diabetic patients attending Kiruddu Referral Hospital, Kampala: Prevalence, Factors and Association with Glycemic control and Insulin resistance
REFNo: HS1853ES

1) To determine the prevalence and factors associated with periodntal disease in patients with diabetes mellitus
2) To determine the bacteria associated with periodntal disease in patients with diabetes mellitus
3) To determine the association between periodntal disease and insulin resistance in patients with diabetes mellitus
Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Degree Award
Victoria Namuggala Flavia
ID: UNCST-2019-R000991
Young Women and Men’s Aspirations and Resilience: Prospects for Livelihoods, Employment and Accountability before, during and beyond COVID – 19
REFNo: SS1093ES

The overall objective of this project is to explore and interrogate the aspirations and resilience of young women and men in Africa; how these may or may not have shifted through the COVID-19 crisis and the implications presented for public policy in Africa with case studies in Ethiopia, Ghana, Kenya, Nigeria, Rwanda, Senegal and Uganda. Specific objectives are to:
1. Examine Ugandan young women and men’s aspirations for their futures.
2. Identify and analyse gender and social norms that guide the lives and aspirations of young men and women in Uganda.
3. Establish whether young women and men’s aspirations have changed with the advent of COVID-19.
4. Analyse what the young women and men are experiencing in their lives and livelihoods in a COVID-19 world.
5. Determine the extent to which the various provisions, regulations and policies in the study countries are aligned with young women and men’s aspirations and ideas about what they see themselves doing in the future.
6. Document lessons learned about the adaptability and resilience of young women and men’s aspirations.

Uganda 2021-11-30 2024-11-30 Social Science and Humanities Non-Clinical Trial Non-degree Award
Stephen Okoboi
ID: UNCST-2019-R001356
Controlled Trial of Game Changers: A Group Intervention to Train HIV Clients to be Change Agents for HIV Prevention in Uganda
REFNo: HS1896ES

1. To conduct a fully powered RCT of Game Changers to test intervention effects on the primary outcomes of increased HIV testing, reduced condomless sex, and decreased enacted HIV stigma among social network members of participating PLWH.
2. To test intervention effects on the secondary outcomes of reduced internalized HIV stigma, increased HIV serostatus disclosure, and increased viral load suppression among participating PLWH, and PrEP uptake among their social network members.
3. To examine whether increased HIV prevention advocacy by PLWH mediates intervention effects on their social network members’ increased HIV testing and condom use, and whether increased HIV disclosure by PLWH mediates intervention effects on social network members’ reduced HIV stigma.
4. To conduct a cost-effectiveness analysis of the intervention.
We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to a no-intervention control
Uganda 2021-11-30 2024-11-30 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Jenna Amlani Nahid
ID:
PATHWAYS FOR AGILE IMPLEMENTATION: IDENTIFYING THE ACTIVE ELEMENTS OF RAISING VOICES’ GOOD SCHOOL TOOLKIT
REFNo: SS1060ES

to elicit feedback from stakeholders on the program and specific activities to improve the GST ,to understand which aspects of the GST most important for changing relationships within schools and ultimately reducing violence against children ,
Canada 2021-11-29 2024-11-29 Social Science and Humanities Non-Clinical Trial Non-degree Award
Kamya Moses
ID: UNCST-2020-R014203
Social-spatial networks and Tuberculosis Infection in Children and Youth in Rural Uganda (SONET)
REFNo: HS1844ES

General Objective
To characterize, on a population-level, where and from which social network youth acquire TB infections and to assess variations throughout stages in the early life-course (early childhood: 1-5 years; school-age: 6-11 years; adolescence: 12-18 years).


Uganda 2021-11-29 2024-11-29 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Arnold Moses  Okello Moses
ID:
Addressing Child Trafficking and Slavery in Uganda (ACTS)
REFNo: SS871ES

1. The Standards of Care (SOC) workstream seeks to develop evidence-based nationwide standards of care for survivors and victims of trafficking and slavery. This will involve a desk-based evidence review, online surveys, workshops with the staff of civil society organisations, and analysis of survivor workshop and monitoring and evaluation data collected by project lead Hope for Justice.
2. The Network Strengthening (NSing) component seeks to engage key stakeholders to strengthen internal technical capacity for the Coalition against Trafficking in Persons in Uganda (CATIPU). The aim of this workstream is to increase the capacity of this network of counter-trafficking civil society organisations to improve prevention, protection prosecution and partnership outcomes and capacity for increased collaboration with wider government structures. Therefore, the Unit of Analysis is the network (see Section 12, page 8 below for more detail).

Uganda 2021-11-26 2024-11-26 Social Science and Humanities Non-Clinical Trial Non-degree Award
Susan Babirye
ID: UNCST-2021-R013201
Analysis of formal and informal institutions of socializing places and their role in shaping vulnerability to HIV: a case of young people (15-24 years) working in socializing places in Uganda
REFNo: HS1536ES

This study aims to analyze formal and informal institutions of socializing places and their role in shaping vulnerability to HIV using a case of YPSP in Uganda. The specific objectives are:
1. To profile socializing places in Uganda and the young people who work in such places
2. To explore the formal and informal institutions of socializing places and their influence on HIV risk and vulnerability of YPSP
3. To determine how YPSP navigate workplace rules and procedures that expose them to HIV risk and vulnerability
4. To explore compliance gaps of the formal and informal institutions of socializing places with the existing laws and opportunities for reducing youth vulnerability to HIV in socializing places

Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Non-Clinical Trial Degree Award
Flavia Matovu Kiweewa
ID: UNCST-2021-R013337
PURPOSE 1: GS-US-412-5624/ A Phase 3, Double-Blinded, Multicenter, Randomized Study to Evaluate Safety and Efficacy of Twice Yearly Long-Acting Subcutaneous Lenacapavir, and Daily Oral Emtricitabine/Tenofovir Alafenamide for Pre-Exposure Prophylaxis in Adolescent Girls and Young Women at Risk of HIV Infection. Version 2.0, dated 10 March 2021.
REFNo: HS1920ES

1. Primary Objectives i) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection. 2. Secondary Objectives/ end points i) To compare the efficacy of LEN with F/TDF for HIV PrEP in AGYW at risk of HIV infection. ii) To evaluate the efficacy of LEN for HIV PrEP in AGYW at risk of HIV infection in participants adherent to LEN. iii) To evaluate the efficacy of F/TAF for HIV PrEP in AGYW at risk of HIV infection in participants adherent to F/TAF. iv) To compare the efficacy of F/TAF with F/TDF for HIV PrEP in AGYW at risk of HIV infection. v) To evaluate the safety and tolerability of LEN, F/TAF, and F/TDF for HIV PrEP in AGYW at risk of HIV infection. vi) To evaluate the safety and tolerability of LEN and F/TAF for HIV PrEP in AGYW ≥ 16 to < 18 years of age who have sex with male partners and are at risk for HIV infection. 3. Exploratory objectives i) To assess the adherence rate to LEN as assessed by on-time LEN injection ii) To assess LEN plasma levels iii) To assess the adherence rate to F/TAF and F/TDF using intracellular TFV-DP levels in DBS. iv) To evaluate the acceptability of a once every 26 weeks LEN injection for HIV PrEP in AGYW at risk of HIV infection. v) To assess LEN plasma levels during pregnancy. vi) To explore concentrations of hormonal contraceptives in LEN participants.
Uganda 2021-11-25 2024-11-25 Medical and Health Sciences Clinical Trial Non-degree Award
Julie Teichroeb Annette
ID:
Social decision-making in Angolan colobus (Colobus angolensis ruwenzorii) and vervet monkeys (Chlorocebus pygerythrus) at Lake Nabugabo
REFNo: NS131ES

Understanding the effects of social constraints on group size and composition, movements, and foraging decisions.
Canada 2021-11-24 2024-11-24 Natural Sciences Non-Clinical Trial Non-degree Award
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