Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Christopher Dolan Gerald
ID:
Improving access and retention in inclusive education for refugee children with disabilities
REFNo: SS937ES

I.To explore stakeholder’s understanding of the processes, challenges and opportunities for refugee children in accessing and progressing in inclusive education
II.To establish the current capacity of the education system to deliver safe and inclusive quality education for refugee children with special needs and disabilities
III.To describe the extent to which RCSN and their caretakers access timely and appropriate support to improve their physical, psychological and social functionality
IV.To establish the extent to which Key stakeholders effectively champion social accountability and implementation of policies and commitments on inclusive education
V.To examine the daily needs of RCWD and their carers

UK 2021-09-23 2024-09-23 Social Science and Humanities Non-Clinical Trial Non-degree Award
Robens Mutatina
ID: UNCST-2021-R013633
Psychosocial challenges and Coping Strategies among Caregivers of Children with Cerebral Palsy in South Western Uganda
REFNo: SS762ES

To determine the psychosocial challenges faced by caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

To describe the coping strategies of caregivers of children with cerebral palsy attending MRRH in southwestern Uganda.

Uganda 2021-09-22 2024-09-22 Social Science and Humanities Non-degree Award
Samuel Biraro
ID:
Assessing the impact of COVID-19 on routine immunization demand and uptake, and understanding COVID-19 attitudes and perceptions in Uganda
REFNo: HS1679ES

1. Identify the range of factors affecting routine immunization uptake during the COVID-19 pandemic in order to inform key areas for mitigation intervention; and
2. Generate timely data on the range of factors that may influence demand and uptake of the COVID-19 vaccines among HCW and the public to identify strategies to promote optimal uptake of the COVID-19 vaccines.


Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Mary  Nanteza Bridget
ID:
ASSESSING A UGANDAN COMMUNITY FOR ACCEPTABILITY, SHORT- AND LONG-TERM SIDE EFFECTS OF COVID-19 VACCINE UPTAKE AND THE COLLECTION OF RELEVANT BIOLOGICAL SPECIMENS TO SUPPORT IMMUNOLOGICAL, HOST, AND VIROLOGICAL STUDIES ON COVID-19 VACCINE.
REFNo: HS1660ES

STUDY GOAL AND OBJECTIVES
The overall objective of this study is to assess acceptability, document short and long-term side effects, characterize break-through viruses that are linked to COVID-19 vaccination, and collect specimens for studies aimed at understanding host, viral and immunological factors associated with COVID-19 vaccine.
Specific objectives:
1. To assess the community knowledge, attitudes and perceptions (KAP) towards COVID-19 vaccines.
2. To describe the short and long-term side effects of COVID-19 vaccine provided at the UVRI clinic
Blood specimens will be collected for the following immunological and virological studies below:
3. To describe the sensitivity of COV ID-19 breakthrough viruses to prior and co-existing anti-SARS-COV-2 antibody and cellular immune responses after immunization with or without prior history of COVID-19 infection; and to also isolate SARS-CoV-2 Spike-specific human monoclonal antibodies in volunteers with strong neutralization responses.
4. To describe the correlation between pre-COVID-19 vaccination immune status, and outcome of vaccine induced immunity in newly vaccinated persons.
5. To describe COVID 19 immune responses in unvaccinated and already vaccinated persons before and after incident infections
6. To describe break-through viruses following COVID-19 immunization among the vaccinated persons

7. To describe host genetic factors that could be relevant for immune protection and disease outcome

Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Eleanor Namusoke Magongo
ID: UNCST-2021-R013199
Transitioning children to Optimal Regimens of Paediatric Dolutegravir (TORPEDO) in Uganda
REFNo: HS1596ES

the primary objective for the study is to assess patients’/ caregivers’ preference for a paediatric DTG regimen over their previous regimen, when transitioned from another regimen.

Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Clinical Trial Non-degree Award
Jihane Farhat Ben
ID:
Evaluation of two strategies part of the Differentiated Services Delivery Models (DSDM) in Fishermen’s landing sites at Lakes George and Edward, Western Uganda.
REFNo: HS1574ES

The main objective of the study is to describe acceptability and outcomes (VL suppression and
retention) relevance of MSF Landing site activities for the target populations to reorient
activities and document best practices.
The specific objectives are:
- To measure the proportion of eligible patients who enrol in CCLADs and FTR
- To compare characteristics of patients choosing CCLAD with those choosing FTR
- To measure the retention in care in CCLADS and in FTR at 6 and 12 months
- To measure the viral suppression for patients enrolled in CCLADS and in FTR for at least 1 year
- To describe acceptability and relevance of DSDM, peer zonal leaders, peers at the health facilities, VIP clinic days, OJT/CMEs for health workers and the information points.

France 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
IVAN IBANDA
ID:
Diagnostic and Treatment Delay of Tuberculosis: An In-depth Analysis of the Health-Seeking Behavior of Patients and the Health System Response in Kampala District
REFNo: HS1654ES

To determine the patient and system related factors that contribute to both diagnosis and treatment delays in Kampala District,To determine the proportion of patients that have a treatment delay for tuberculosis in Kampala District.,To determine the proportion of patients with tuberculosis diagnostic delay in Kampala District.,To evaluate the extent of diagnostic and treatment initiation delays of TB patients, identify the major contributors to such delays (patient or system), and study their various determinants.,
Uganda 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Goylette Chami
ID: UNCST-2023-R006262
SchistoTrack: Determinants of schistosomiasis infection and morbidity as part of the Oxford-Uganda Collaboration on Schistosomiasis
REFNo: HS1664ES

Determine whether infection indicators are informative for measuring morbidity risks
associated with schistosomiasis;
2. Prioritize the most common morbidities associated with schistosomiasis, by age, that
require treatment and further research;
3. Understand the relative importance of environmental factors versus current infections for
schistosomiasis- associated morbidities.
4. Assess the feasibility of large-scale tracking of individuals with wearable GPS;
5. Determine whether spatial indicators from wearable devices can better predict individual
infection risk when compared to conventional approaches such as household surveys;
and
6. Develop methods to classify water contact sites based on individual usage and
contamination to understand whether there are focal points for transmission or super
spreaders.
USA 2021-09-22 2024-09-22 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Freddy Kitutu Eric
ID: UNCST-2020-R014751
Development and implementation of a patient-centred peer support intervention to promote the detection, reporting and management of adverse drug reactions among people living with HIV in Uganda
REFNo: HS1206ES

To estimate the effectiveness of the peer support intervention on the rate of ADR-reporting by PLHIV receiving DTG and/or IPT in Uganda,To describe the patterns of ADR-reporting (number, rate, time to reporting, seriousness) by PLHIV receiving DTG and/or IPT in whom the peer support intervention is implemented in Uganda,To determine the barriers and facilitators to implementation of the peer support intervention to promote ADR detection, reporting and management among PLHIV on DTG and/or IPT in Uganda,To develop an innovative peer support intervention for promoting the detection, reporting and management of ADRs in PLHIV receiving DTG and/or IPT in Uganda,
Uganda 2021-09-21 2024-09-21 Medical and Health Sciences Non-degree Award
Maxson Anyolitho Kenneth
ID: UNCST-2021-R013447
Community Engagement and Schistosomiasis Prevention: A Sociological Analysis of the Citizen Science Model among Selected Communities of Western Uganda
REFNo: SS836ES

Purpose of the study
The purpose of the study is to examine the effectiveness of the Citizen Science model in community engagement to the prevention of schistosomiasis among selected communities of western Uganda. To do this, the study will determine the socio-cultural barriers to the uptake of preventive measures to guide in the development of health education initiatives that can be executed by the Citizen Scientists to help change the behaviour of the community for the prevention of schistosomiasis.

Objectives of the study
This shall be guided by the following research objectives:
1. To determine the level of knowledge, attitude, and practice regarding schistosomiasis among communities of Western Uganda;
2. To explore the health-seeking practices, attitudes, and behaviour associated with schistosomiasis prevention among communities of Western Uganda
3. To understand the lived experiences and perceptions of schistosomiasis by communities of Western Uganda to determine how citizen scientists can be useful in shaping community perspectives
4. To develop and implement contextualized communication strategies for schistosomiasis prevention based on the outcome of the objectives above with help of the citizen scientists
5. To assess the role of the citizen science model of community engagement in the prevention of schistosomiasis among communities of western Uganda

Uganda 2021-09-21 2024-09-21 Social Science and Humanities Non-Clinical Trial Degree Award
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