Approved Research This page provides a searchable list of all research protocols that have been reviewed and approved by the Uganda National Council for Science and Technology(UNCST).
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Name Title Nationality Approval Date Expiry Date Field of Science/Classification Trial Type Research Type  
Akatukwasa  Cecilia
ID: UNCST-2021-R013537
PrEP preferences around the time of pregnancy among mobile women.
REFNo: SS1105ES

The objective of this study is to elucidate the role of mobility in attitudes and preferences regarding PrEP initiation and engagement during the perinatal period.
Uganda 2021-12-09 2024-12-09 Social Science and Humanities Non-Clinical Trial Non-degree Award
Jane  Kabami
ID: UNCST-2021-R012588
Effects of the COVID-19 pandemic on the HIV Care Continuum in South Western Uganda
REFNo: HS1855ES

1.To evaluate the effect of the COVID-19 pandemic across the HIV Care Cascade including: ART initiation, retention in care, and viral suppression among PLWH in South Western Uganda
To explore the changing practices, barriers and facilitators to the delivery of HIV services during the COVID-19 pandemic from the perspective of PLWH, health workers and community members
Uganda 2021-12-08 2024-12-08 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Deborah Ekusai-Sebatta
ID: UNCST-2021-R003878
Willingness and Feasibility of Using Injectable Antiretroviral Therapy Among Women From Prevention- of- Mother- to- Child- HIV- Transmission- Programs In Uganda
REFNo: SS1095ES

Aim 1: To explore participant perceptions about willingness to use and roll out of LART in PMTCT programs.
Aim 2: To explore the fears, concerns, potential barriers and hindrances in delivering LART to women in PMTCT programs.
Aim 3: To establish the health facility readiness of PMTCT programs to support LART

Uganda 2021-12-08 2024-12-08 Social Science and Humanities Non-Clinical Trial Non-degree Award
Shillah  Kwikiiriza
ID: UNCST-2021-R012682
Improving the production and marketing of squash by smallholder youth farmers in Kamuli, Uganda
REFNo: A76ES

1.evaluate the effect(s) of soil mulching and cultivar for improved squash production and yield. 2.determine market vendor requirements for buying and selling of squash. 3.determine the partial cost budgets and the gross margin of cultivars of squash produced with or without soil mulch and in experimental plots. 4.investigate the potential of farmer cooperatives for in- and out of school youth farmers (15 – 35 years) participating in schools’ home gardening projects.
Uganda 2021-12-07 2024-12-07 Agricultural Sciences Non-Clinical Trial Degree Award
JULIET MWANGA-AMUMPAIRE
ID: UNCST-2022-R009420
An open-label, multicentre, randomized, adaptive platform trial of the safety and efficacy of several therapies, including antiviral therapies, versus control in mild/moderate cases of COVID-19
REFNo: HS1789ES

Primary objective: to compare the efficacy of alternative treatment strategies versus control on the risk of progression to severe respiratory disease
The secondary objectives are:
ï‚§ To compare the safety of each study arm to control, up to Day 21 of follow-up
ï‚§ To compare the rate of hospitalizations due to COVID-19 in each study arm versus control
ï‚§ To compare the time to hospitalization due to COVID-19 in each study arm versus control
ï‚§ To compare the rate of hospitalizations for other reason than Covid-19 in each study arm versus control
ï‚§ To compare the disease-free rate in each study arm versus control
ï‚§ To compare the death rate in each study arm versus control
ï‚§ To compare time to worsening of SpO2 < 93in each study arm versus control
ï‚§ To compare the capacity to prevent severe progression between study arms
ï‚§ To identify risk factors for severe progression
ï‚§ To assess efficacy in sub-groups of patients e.g. with pre-existing conditions/co-morbidities, by age group, sex, BMI, timeframe between onset of symptoms and randomization.

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Clinical Trial Non-degree Award
Herbert Muyinda
ID: UNCST-2019-R000373
Cango Lyec Study (Healing the Elephant): Developing and Testing Interventions to Reduce HIV Risk, Increase Access to Treatment and Promote Resilience in War Affected Populations in Northern Uganda (Follow-up Study)
REFNo: HS1816ES

To pilot the feasibility and acceptability of Wayo/Nero and mHealth intervention packages to support both prevention and care for HIV/AIDS, Hepatitis B, and war related trauma.,Investigate associations between posttraumatic stress, resilience, and depression, with HIV/Hepatitis B incidence among conflict-affected populations in Northern Uganda,Estimate prevalence and incidence of HIV, syphilis, Hepatitis B, and identify associated risk factors among conflict-affected populations in Northern Uganda ,Our overarching goal is to develop, test and scale up culturally-safe, strengths-based, trauma-informed, technology-enhanced (CSTT) interventions among war affected populations. ,
Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Edith Wakida K
ID: UNCST-2019-R001225
Enhancing the Capacity for Providers in Mental Health Integration (ECaP-MHI): A pilot intervention study in Lira district, Northern Uganda
REFNo: HS1847ES

1.4.1 To gather baseline data on the mental disorder diagnoses recorded by PHCPs at a selected HC IV in Lira district before the pilot intervention (in objective four)
1.4.2 To explore contextual barriers and/or challenges likely to affect the ability of Lira DHMT to support PHCPs using the adapted ECaP-MHI intervention
1.4.3 To adapt the training component of the ECaP-MHI intervention
1.4.4 To assess implementation of the DHMTs supporting PHCPs to integrate mental health
services into using the adapted ECaP-MHI intervention
Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Tana Chongsuwat
ID:
Evaluation of Understanding, Perceptions, and Attitudes Toward Cervical Cancer Screening, Prevention, and Treatment Services Available to Women in Gulu City, Uganda
REFNo: HS1862ES

Understand attitudes and perceptions regarding seeking cervical cancer screening, treatment, or prevention services.,Assess the level of knowledge of men and women on cervical cancer etiology, risk factors, screening, and prevention services available to them.,
USA 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Ezekiel Mupere
ID: UNCST-2021-R011972
Adaptive immunity to Mtb-infection and TB disease among young Ugandan children”
REFNo: HS1870ES

1.To recruit Ugandan children 5 years and younger (< 60 months), with and without perinatal HIV-exposure and/or infection, who are household contacts of an adult with confirmed TB disease
2.To identify immunologic phenotypes that correlate with TB disease, versus remaining asymptomatic following TB household contact, in young children with and without perinatal HIV-exposure and/or infection
3.To determine if MTB-specific T cell and/or antibody profiles can be used to distinguish TB disease from asymptomatic MTB infection, in young children with and without perinatal HIV-exposure and/or infection
4.To determine how perinatal HIV exposure/infection alters MTB-specific adaptive immune profiles

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
Richard Muhindo
ID:
Tackling coronavirus disease-2019 Vaccine Hesitancy among People Living with HIV in Kampala, Uganda
REFNo: HS1902ES

To describe the prevalence and factors associated with COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
2. To explore the drivers of COVID-19 vaccine hesitancy among adult PLHIV in Kampala, Uganda.
3. To develop and pilot educational materials to promote COVID-19 vaccine uptake among adult PLHIV in Kampala, Uganda

Uganda 2021-12-07 2024-12-07 Medical and Health Sciences Non-Clinical Trial Non-degree Award
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